Eumetopias jubatus (Steller sea lion): 114215501 Help Entry 114215501         CDS       T07240                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism eju  Eumetopias jubatus (Steller sea lion) Pathway eju04072   Phospholipase D signaling pathway eju04115   p53 signaling pathway eju04140   Autophagy - animal eju04150   mTOR signaling pathway eju04151   PI3K-Akt signaling pathway eju04152   AMPK signaling pathway eju04211   Longevity regulating pathway eju04218   Cellular senescence eju04714   Thermogenesis eju04910   Insulin signaling pathway eju04919   Thyroid hormone signaling pathway eju05163   Human cytomegalovirus infection eju05165   Human papillomavirus infection eju05168   Herpes simplex virus 1 infection eju05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:eju00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     114215501 (TSC2)    04151 PI3K-Akt signaling pathway     114215501 (TSC2)    04152 AMPK signaling pathway     114215501 (TSC2)    04150 mTOR signaling pathway     114215501 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     114215501 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     114215501 (TSC2)    04218 Cellular senescence     114215501 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     114215501 (TSC2)    04919 Thyroid hormone signaling pathway     114215501 (TSC2)   09149 Aging    04211 Longevity regulating pathway     114215501 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     114215501 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     114215501 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     114215501 (TSC2)    05163 Human cytomegalovirus infection     114215501 (TSC2)    05165 Human papillomavirus infection     114215501 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:eju01009]     114215501 (TSC2) Protein phosphatases and associated proteins [BR:eju01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      114215501 (TSC2) SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP HEAT Cnd1 Motif Other DBs NCBI-GeneID:  114215501 NCBI-ProteinID:  XP_027967295 LinkDB All DBs Position Unknown AA seq 1747 aa AA seqDB search MAKPTSKDSGLKEKFRILLGLGTPRPNPRSAEGKQTEFIITADILRELSVECGINNRIRV IGQICEVAKTKKFEEHAVEALWKAVADLLHPERPPEARHAVLALLKAIVQGQGDRLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAGFVLQWMDIGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMICLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRRELQAVAWDI LLNIMERLLQQLQSLDSPELRAIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE SSLLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNESRSAVRIKVLDVLSFVLLINRQFY EEELISSVVISQLSHVPEDKDPQVRKLATQLLVDLAEGCHTHHFNSLLDIVEKVIARSLS PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYALPASHAVRVYETLVSHMELHYRR DYTLPIASSIRLQAFDFLLLLRADSLHRLGLPSKDGAVRFSPYCVCDAMEPERGPEKKAS GPLSPPTGPPGSAPVGPAVRLGSLPYSLLFRVLLQCLKQEADWKVLKLVLSKLPESLRYK VLIFTSPCSVDQLSSALCSVLSGPRTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL DKTRQREMVYCLEQGLIHRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPFITKGLRSNVLLPFDDTPEKDSFRARSTSLNERPKSRIQTSLTSASLGSA DENSMAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVG NKLVTVTTSVGTGTRSLLGLDSGELQGGPESSSDPGAHVRQTKEAPAKLESQAGQQVCRG ARDRVRSMSGGHGLRVGALDSPASHFPGGPTSPGAQTALTSKSERASAGTQFPVQEKTSL AAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKE RRDTALYKSLSVPAAGSSKPPPPPRSNTDSAVVPEEGSTSETHLSAEPMELEDFEATLGT DRRGDRAEAYSRSSSSSSQEEKFPAEELAAGGIPIERAVSSEGTRPSVELSFQPSQPLSK SSSSPELQTLQDVLGDPGDKTDVGRLSPEAKARSQSGILDGAGASWSAPGAESRGRGPAQ PEGPLPSSCPRSPSGLRPRGYTISDSAPSRRGKRAEKDAFKSRAGASNTEKVPGINPSFV FLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSSSELAIL SNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIA TLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIRGQFNFVHVIITPLDYECNL VTLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIA RLRHIKRLRHRIREEAHYSNPSLPLMQMHPPGHAKAPAQAPAEPTPTYETGQRKRLISSV DDFTEFV NT seq 5244 nt NT seq  +upstreamnt  +downstreamnt atggccaagccaacaagcaaagattcaggcttgaaggagaagttcaggattctcttggga ctgggaaccccgaggccaaaccccaggtctgcagagggcaaacagacggagtttatcatc acggcggacatcctgagagaactgagtgttgaatgtggtatcaacaatcgcatccgggtg atagggcagatctgtgaagttgcaaaaacgaagaaatttgaagagcatgccgtggaggcg ctgtggaaggccgtggcggacctgctgcacccggagcggcccccggaggcccggcatgcg gtgctggctctgctgaaggccatcgtgcagggacagggggaccggttgggtgttctcagg gccctcttcttcaaggtcataaaggattacccctctaatgaagacctccacgagagactg gaagtgttcaaggccctcacggacaatgggagacacatcacctacttggaagaagaactg gctgggtttgtcctgcagtggatggacatcggcctatcctcagaattcctcctggtgctt gtgaacttggtcaagttcaacagctgctacctggatgaatatattgcatcaatggtccac atgatctgcctgttgtgcgtccagaccgtgtcgtccgtggacatagaggtctccctgcag gtgctggatgccgtggtctgttacaactgcctgccggctgagagcctccccctgttcatt gtcaccctctgccgtaccatcaatgtcaaggagctttgtgagccttgctggaagctgatg cgtaacctcctgggcacccacctgggccacagtgccatctacaacatgtgtcgtatcatg gaggacagagcctacatggaagatgccccactgctgagaggggctgtgttctttgtgggc atggcgctctggggagcgcaccgactctactccctcaagaactccccgacgtccgtgctg ccatcgttttatgaggccatgacctgtccaaacgaggtggtgtcctacgaaatcgtgctt tctataaccagactcatcaagaagtaccgcagggagctccaggctgtggcgtgggacatc ctgctgaacatcatggagcgcctgcttcagcagctccagagcctggacagcccagagctc agagctatcgtccacgacctgctgaccacagtggaagagctgtgtgaccagaacgagttc cacggctctcaggagagatactttgagctggttgagcgatgcgcagaccagaggcctgag tcctccctcttaaacttaataacctacagggcacagtcaatccatccggcgaaggacggc tggattcacaacctgcagttgctgatggagagattcttcaggaatgaatcccgcagtgcc gttcgcatcaaggtgctggatgtcctgtccttcgtgctgctcatcaacaggcagttctat gaggaggagctgatcagctcagtggtcatctcccagctctcccacgtccctgaggacaaa gacccccaagtccggaaactggccacccagttgctggtggacctggccgaaggctgtcat acccaccacttcaacagcctgctggacattgtggaaaaggtgattgcccgctccctttct ccaccccctgagctggaggagagagatgtggcggcgtactcagcctccttagaggatgtg aagaccgccgtcttggggctcctggtcatccttcagaccaagctgtacgccttgcctgcc agccacgcggtgcgtgtgtacgagacgctcgtcagccacatggagctgcattacaggcgc gactacaccctacccatcgcaagcagcatccggctgcaggccttcgacttcctgctgctg ctgagggccgactcactgcaccgcctcggcctgcccagcaaggatggggccgtgaggttc agcccttactgcgtctgtgacgccatggagccggagaggggcccggagaagaaggccagc ggccccctgtcgcctcccaccgggccgcctggctctgcgcccgtaggccccgcggtgcgg ctcggctctctgccctactccctgctcttccgcgtcctcctacagtgcttgaagcaggag gcagactggaaggtgctgaagctcgtgctcagcaagctgcccgagtccctgcgctacaag gtgctcatcttcacgtctccgtgcagcgtcgaccagctgtcttccgccctctgctccgtg ctttcaggtcccagaaccctggagcggcttcgaggcaccccggaaggattttccagaacc gacctgcatctggctgtggttcctgtgctgacggcgctgatctcttaccataattacttg gacaagaccagacagcgggagatggtgtactgcctggagcaaggcctgatccaccgctgt gctagccagtgtgtggtggcgttggccatctgcagcgtggagatgcccgacatcatcatt aaggcgcttcccgtcctggtcgtgaagctcacacacatctcagccacggccagcatggcc attccacttctcgaattcttatcaactctggcccggctgccccacctctaccggaacttt gcagctgagcagtacgcgagcgtctttgccatttccctgccttacaccaacccctccaag tttaatcagtacatcgtgtgcttggcccatcatgttatagccatgtggttcattagatgc cgcctgcccttccggaaggattttgttccttttatcactaagggcttgcgctccaacgtt ctcctgcccttcgatgacacccctgagaaggacagcttcagagctcgaagcaccagtctc aacgagaggcccaagagcaggatccagacgtccctcaccagcgccagcttggggtctgca gatgagaattcgatggcccaggctgatgacaacttgaaaaatctccacctggagctcaca gaaacatgtctggacatgatggccagatacgtgttctccaatttcacagcggttcccaag aggtcacctgtgggcgagttcctcctggctggtggcaggaccaaaacctggctggttggg aacaagcttgttaccgtgacaacgagcgtggggaccgggacccggtcgctgctgggcttg gattcaggagagctgcagggtggccccgagtcgagctcagaccctggcgcgcatgtgaga cagaccaaggaggcgcctgccaagctggagtcccaggctgggcagcaggtgtgccgcggg gcccgggaccgggtccgctccatgtccgggggccatggccttcgtgttggtgccctggac agtccagcctcccacttcccgggtggccccacttccccgggtgcacagactgctctcacc agcaagtctgagagggcgtcagctggtacccagttcccagtgcaggagaagacgagcctg gcagcctatgtccccctgctgacccagggctgggcagagatcctggtccggaggcccaca gggaacaccagttggctgatgagcctggagaacccactcagccccttctcctcagacatc aacaacatgcccctgcaggagctgtccaacgcgctcatggccgccgagcgctttaaggag cgtcgcgacacagctctgtacaagtcgctgtcggtgccggcggcgggctcatccaagccc cctccacccccgcggtctaacacggactcggcagtggttccggaggaggggagcacaagc gagactcatttgtccgcggagcccatggagttggaggactttgaggcgacgctaggcaca gaccggcgtggtgaccgtgctgaggcttacagcaggtcatcttcaagctccagccaagag gagaagttccctgcagaggagctggcggctggagggatccccatcgagcgggccgtctct tctgagggcacccggccttctgtggagctctccttccagccctcccagcccctcagcaag tccagctcctcgcctgagctgcagaccctgcaggacgtgctgggggaccctggagacaag actgacgttggccggctgagccctgaggccaaggcccggtcgcagtccgggatcctggac ggggcaggtgcctcctggtcagccccaggcgcagagagccggggccggggccccgcgcag cccgagggtcccttgccttctagctgcccccgctcccccagtggcctgcggcccagaggc tacaccatctctgattcggccccatcacgcagaggcaagagagcagagaaggacgccttc aagagcagagcgggggcctccaatactgagaaggtgccaggcatcaatcccagttttgtg ttcctgcaactctaccattcacctttctttggtgacgagtccaacaagcccatccttcta cccaatgagtccttcgagcggtcagtgcagcttctcgaccagattccatcctatgacacg cacaagattgccgtcctgtacgtgggagaaggccagagcagcagcgagctggccatcctg tccaatgagcacggctcgtacaggtacacggagttcctgaccggcctgggcaagctcatc gagctcaaggactgccagccggacaaggtgtacctggggggtctggatgtgtgtggggag gacggccagtttacctactgctggcacgacgacatcatgcaagctgtcttccacatcgcc accctgatgcccaccaaggacgtggacaagcaccgctgtgacaagaagcgtcatctgggc aatgacttcgtgtccattgtgtacaatgactccggcgaggacttcaagctgggcaccatc agaggtcagttcaacttcgtccatgtcatcatcacccccctggactatgagtgcaacctg gtgaccctgcagtgcaggaaagacatggagggtctcgtggataccagcgtggccaagatc gtgtcagaccgcaacctgccttttgtggcccgtcagatggctctgcacgcaaacatggcc tcacaggtacatcacagccgctccaaccccactgacatctacccctccaagtggatcgcc aggctccgccacatcaagcggctccgccaccggatccgggaggaagcccactattccaac cccagcctgcccctgatgcagatgcaccccccgggccacgccaaagcccctgctcaggcg ccggcagagcccacgcccacgtatgagacgggccagcggaagcgcctcatctcctcagtg gatgacttcacggagttcgtgtga

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