KEGG   Eumetopias jubatus (Steller sea lion): 114216197
Entry
114216197         CDS       T07240                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
eju  Eumetopias jubatus (Steller sea lion)
Pathway
eju04010  MAPK signaling pathway
eju04015  Rap1 signaling pathway
eju04218  Cellular senescence
eju04380  Osteoclast differentiation
eju04620  Toll-like receptor signaling pathway
eju04664  Fc epsilon RI signaling pathway
eju04668  TNF signaling pathway
eju04750  Inflammatory mediator regulation of TRP channels
eju04912  GnRH signaling pathway
eju04935  Growth hormone synthesis, secretion and action
eju04936  Alcoholic liver disease
eju05014  Amyotrophic lateral sclerosis
eju05022  Pathways of neurodegeneration - multiple diseases
eju05132  Salmonella infection
eju05135  Yersinia infection
eju05145  Toxoplasmosis
eju05161  Hepatitis B
eju05163  Human cytomegalovirus infection
eju05167  Kaposi sarcoma-associated herpesvirus infection
eju05169  Epstein-Barr virus infection
eju05170  Human immunodeficiency virus 1 infection
eju05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
eju05417  Lipid and atherosclerosis
eju05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:eju00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114216197 (MAP2K6)
   04015 Rap1 signaling pathway
    114216197 (MAP2K6)
   04668 TNF signaling pathway
    114216197 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    114216197 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    114216197 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    114216197 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    114216197 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    114216197 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    114216197 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    114216197 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    114216197 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    114216197 (MAP2K6)
   05161 Hepatitis B
    114216197 (MAP2K6)
   05163 Human cytomegalovirus infection
    114216197 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    114216197 (MAP2K6)
   05169 Epstein-Barr virus infection
    114216197 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    114216197 (MAP2K6)
   05135 Yersinia infection
    114216197 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    114216197 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    114216197 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    114216197 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    114216197 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    114216197 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    114216197 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:eju01001]
    114216197 (MAP2K6)
Enzymes [BR:eju01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     114216197 (MAP2K6)
Protein kinases [BR:eju01001]
 Serine/threonine kinases: STE group
  STE7 family
   114216197 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 114216197
NCBI-ProteinID: XP_027968440
LinkDB
Position
Unknown
AA seq 334 aa
MSQSKGRKRNPGLKIPKEAFEQPQPSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSDEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaggaagcgaaaccctggccttaaaattccaaaagaagcattt
gaacaacctcagcccagttccacgccacctcgagacttagactctaaagcttgcatttct
attggaaatcagaactttgaggtgaaagcagatgacctggagcctataatggaactgggg
cgaggtgcgtacggggtggtggagaagatgcgacacgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacagtaaatagccaggagcagaaaaggctactgatggatttg
gatatttccatgaggacagtggactgtccttttaccgtcaccttttatggtgcactcttc
cgggagggtgatgtttggatctgcatggagctcatggatacgtcgctagataaattctac
aaacaagtgatcgataaaggccaaacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagctttagaacacttacacagtaagctctctgtcattcatcgagacgtc
aagccttccaacgtgctgatcaacactctgggccaagtaaagatgtgcgattttggaatc
agtggctaccttgtagactctgtcgctaaaactattgatgcaggatgcaaaccgtacatg
gcccctgaaagaataaacccagagctcaaccagaagggatacagtgtgaagtctgacatt
tggagtctgggcatcacaatgattgagttggcgatccttcggtttccctacgactcttgg
ggaacccccttccagcagctcaaacaggtggtcgaggaaccctcaccacaactcccggca
gacaaattctccgacgagtttgttgactttacctcacagtgcttgaagaagaattccaaa
gaacggccaacatatccagagcttatgcaacatccatttttcaccctacacgaatccaaa
gcaacagacgtggcatcttttgtaaaactgattcttggagactaa

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