Eumetopias jubatus (Steller sea lion): 114217524 Help Entry 114217524         CDS       T07240                                  Symbol HIF1A Name (RefSeq) hypoxia-inducible factor 1-alpha   KO K08268   hypoxia-inducible factor 1 alpha Organism eju  Eumetopias jubatus (Steller sea lion) Pathway eju04066   HIF-1 signaling pathway eju04137   Mitophagy - animal eju04140   Autophagy - animal eju04148   Efferocytosis eju04659   Th17 cell differentiation eju04919   Thyroid hormone signaling pathway eju05167   Kaposi sarcoma-associated herpesvirus infection eju05200   Pathways in cancer eju05205   Proteoglycans in cancer eju05208   Chemical carcinogenesis - reactive oxygen species eju05211   Renal cell carcinoma eju05230   Central carbon metabolism in cancer eju05231   Choline metabolism in cancer eju05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:eju00001]  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     114217524 (HIF1A)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     114217524 (HIF1A)    04137 Mitophagy - animal     114217524 (HIF1A)    04148 Efferocytosis     114217524 (HIF1A)  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     114217524 (HIF1A)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     114217524 (HIF1A)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     114217524 (HIF1A)    05205 Proteoglycans in cancer     114217524 (HIF1A)    05208 Chemical carcinogenesis - reactive oxygen species     114217524 (HIF1A)    05230 Central carbon metabolism in cancer     114217524 (HIF1A)    05231 Choline metabolism in cancer     114217524 (HIF1A)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     114217524 (HIF1A)   09162 Cancer: specific types    05211 Renal cell carcinoma     114217524 (HIF1A)   09172 Infectious disease: viral    05167 Kaposi sarcoma-associated herpesvirus infection     114217524 (HIF1A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:eju03000]     114217524 (HIF1A) Transcription factors [BR:eju03000]  Eukaryotic type   Basic helix-loop-helix (bHLH)    Factors with PAS domain     114217524 (HIF1A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  bHLH_HIF1A PAS_3 PAS_11 HIF-1a_CTAD PAS HIF-1 PAS_9 PAS_4 HLH DDRGK Motif Other DBs NCBI-GeneID:  114217524 NCBI-ProteinID:  XP_027970230 LinkDB All DBs Position Unknown AA seq 822 aa AA seqDB search MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGR TMNIKSATWKVLHCTGHIHVYDTNSNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTET DDQQLEEVPLYNDVMLPSSNDKLQSINLAMSPLPASETPKPLRSSADPALNQEVALKLEP NPESLELSFTMPQIQDQPASPSDGSTRQSSPEPNSPSEYCFDVDSDMVNEFKLELVEKLF AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSTNPQSASTVTVFQ PTQIQEPPVTTTSTTTTDELKTVTKDGIEDIKILIASPSPTHVPKVTASATTSPYSDTGS RTASPNRAGKGVIEQTEKSHPRSPNVLSVTLSQRTTIPEEELNPKILALQNAQRKRKIEQ DGSLFQAVGIGTLLQQPDDRAATTSLSWKRVKGCKSSEHSGMEQKTIILIPSDLACRLLG QSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN NT seq 2469 nt NT seq  +upstreamnt  +downstreamnt atggagggcgccggcggcgcgaacgacaagaaaaagataagttctgaacgtagaaaagaa aagtctagagatgcagctagatctcggagaagtaaagagtccgaagttttttatgagctt gctcatcagttgccacttccccataatgtgagctcgcatcttgataaggcttctgttatg aggcttaccatcagctatttgcgtgtaaggaaacttctggatgctggtgatttagatatt gaagatgaaatgaaggcacagatgaattgcttttatttgaaagccctagatggttttgtt atggttctcacagatgatggtgacatgatttacatttctgataatgtgaataaatacatg ggattgactcagtttgaactaactggacacagtgtgtttgattttactcatccatgtgac catgaggaaatgagagaaatgcttacacacagaaatggccttgtgaaaaagggtaaagag cagaatacacagcgaagcttttttctcagaatgaagtgtaccctaactagccgggggaga actatgaacataaagtcagcaacatggaaagtacttcactgcacaggccatattcatgtc tacgataccaacagtaaccaatctcagtgtgggtataagaaaccacccatgacgtgcttg gtgctaatttgtgaacccattcctcatccatcaaatattgaaattcctttagatagcaag acttttctcagtcgtcacagtctggatatgaaattttcttactgtgatgaaagaattact gaattgatgggatatgagccagaagaacttttgggccgctcaatttatgaatattatcat gctttggactctgaccatctgaccaaaactcatcatgatatgtttactaaaggacaagtc accacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaactcaa gcaactgtcatatataacactaagaactctcaaccacagtgcattgtatgtgtaaattat gttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgtgtc ctcaaaccagttgaatcttcagatatgaaaatgactcagctattcaccaaagttgaatca gaagatacaagtagtctctttgataaacttaagaaggaacctgatgctttaactttgctg gccccagctgctggagacacaatcatatctttagatttcggcagcaatgacacagaaact gatgaccaacaacttgaggaggttccgttgtataatgatgtaatgctcccctcatccaac gacaaattacagagtataaatttggcaatgtctcccttacctgcttctgaaactccaaag ccacttcgaagtagtgctgatcctgcactcaatcaagaagttgcattaaaattagagcca aatccagagtccctggaactttcttttactatgccccagattcaagatcagccagctagt ccttctgatggaagcactagacaaagttcacctgagcctaacagtcccagtgaatattgt tttgatgtggatagtgatatggtcaatgaatttaagctggaattagtagagaaacttttt gctgaagacacagaagcaaagaatccattttccacccaggacactgatttagacttggag atgttagctccttatatcccaatggatgatgacttccagttacgttccttcgatcagttg tcaccgctggaaagcagttctacgaaccctcaaagtgcgagcacagttacagtattccag ccgacgcaaattcaagagcctcctgttaccactaccagtaccactaccactgatgaatta aaaacagtgacaaaagatggtatagaagacattaaaatattgattgcatctccatctcct acccatgtacctaaagtaactgctagtgccacaacatcaccatacagtgatactggaagt cggacagcctcaccaaacagagcaggaaaaggagtcatagaacagacagaaaaatctcat ccaagaagccctaacgtgttatctgtcactttgagtcaaagaactaccattcctgaggaa gaactaaatccaaagatactagctttgcagaatgctcagagaaagcgaaaaatagaacag gatggttcactttttcaagcagtaggaattggaacattattacagcagccagacgatcgt gcagctactacatcactttcttggaagcgcgtaaaaggatgcaaatctagtgaacacagt ggaatggagcaaaagacaattattttaataccctctgatttagcgtgtagactgctgggg caatcaatggatgagagtggattaccacaactgaccagttatgattgtgaagttaatgct cctatacaaggcagcagaaacctactgcagggtgaagaattactcagagctttggatcaa gttaactga

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