KEGG   Eumetopias jubatus (Steller sea lion): 114217931
Entry
114217931         CDS       T07240                                 
Symbol
NFKBIA
Name
(RefSeq) NF-kappa-B inhibitor alpha isoform X1
  KO
K04734  NF-kappa-B inhibitor alpha
Organism
eju  Eumetopias jubatus (Steller sea lion)
Pathway
eju04024  cAMP signaling pathway
eju04062  Chemokine signaling pathway
eju04064  NF-kappa B signaling pathway
eju04210  Apoptosis
eju04380  Osteoclast differentiation
eju04519  Cadherin signaling
eju04620  Toll-like receptor signaling pathway
eju04621  NOD-like receptor signaling pathway
eju04622  RIG-I-like receptor signaling pathway
eju04623  Cytosolic DNA-sensing pathway
eju04625  C-type lectin receptor signaling pathway
eju04657  IL-17 signaling pathway
eju04658  Th1 and Th2 cell differentiation
eju04659  Th17 cell differentiation
eju04660  T cell receptor signaling pathway
eju04662  B cell receptor signaling pathway
eju04668  TNF signaling pathway
eju04722  Neurotrophin signaling pathway
eju04920  Adipocytokine signaling pathway
eju04926  Relaxin signaling pathway
eju04931  Insulin resistance
eju04936  Alcoholic liver disease
eju05132  Salmonella infection
eju05134  Legionellosis
eju05135  Yersinia infection
eju05140  Leishmaniasis
eju05142  Chagas disease
eju05145  Toxoplasmosis
eju05160  Hepatitis C
eju05161  Hepatitis B
eju05162  Measles
eju05163  Human cytomegalovirus infection
eju05164  Influenza A
eju05166  Human T-cell leukemia virus 1 infection
eju05167  Kaposi sarcoma-associated herpesvirus infection
eju05168  Herpes simplex virus 1 infection
eju05169  Epstein-Barr virus infection
eju05170  Human immunodeficiency virus 1 infection
eju05171  Coronavirus disease
eju05200  Pathways in cancer
eju05203  Viral carcinogenesis
eju05208  Chemical carcinogenesis - reactive oxygen species
eju05215  Prostate cancer
eju05220  Chronic myeloid leukemia
eju05222  Small cell lung cancer
eju05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
eju05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:eju00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    114217931 (NFKBIA)
   04668 TNF signaling pathway
    114217931 (NFKBIA)
   04024 cAMP signaling pathway
    114217931 (NFKBIA)
  09133 Signaling molecules and interaction
   04519 Cadherin signaling
    114217931 (NFKBIA)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    114217931 (NFKBIA)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    114217931 (NFKBIA)
   04621 NOD-like receptor signaling pathway
    114217931 (NFKBIA)
   04622 RIG-I-like receptor signaling pathway
    114217931 (NFKBIA)
   04623 Cytosolic DNA-sensing pathway
    114217931 (NFKBIA)
   04625 C-type lectin receptor signaling pathway
    114217931 (NFKBIA)
   04660 T cell receptor signaling pathway
    114217931 (NFKBIA)
   04658 Th1 and Th2 cell differentiation
    114217931 (NFKBIA)
   04659 Th17 cell differentiation
    114217931 (NFKBIA)
   04657 IL-17 signaling pathway
    114217931 (NFKBIA)
   04662 B cell receptor signaling pathway
    114217931 (NFKBIA)
   04062 Chemokine signaling pathway
    114217931 (NFKBIA)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    114217931 (NFKBIA)
   04926 Relaxin signaling pathway
    114217931 (NFKBIA)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    114217931 (NFKBIA)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    114217931 (NFKBIA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    114217931 (NFKBIA)
   05208 Chemical carcinogenesis - reactive oxygen species
    114217931 (NFKBIA)
   05203 Viral carcinogenesis
    114217931 (NFKBIA)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    114217931 (NFKBIA)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    114217931 (NFKBIA)
   05215 Prostate cancer
    114217931 (NFKBIA)
   05222 Small cell lung cancer
    114217931 (NFKBIA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    114217931 (NFKBIA)
   05170 Human immunodeficiency virus 1 infection
    114217931 (NFKBIA)
   05161 Hepatitis B
    114217931 (NFKBIA)
   05160 Hepatitis C
    114217931 (NFKBIA)
   05171 Coronavirus disease
    114217931 (NFKBIA)
   05164 Influenza A
    114217931 (NFKBIA)
   05162 Measles
    114217931 (NFKBIA)
   05168 Herpes simplex virus 1 infection
    114217931 (NFKBIA)
   05163 Human cytomegalovirus infection
    114217931 (NFKBIA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    114217931 (NFKBIA)
   05169 Epstein-Barr virus infection
    114217931 (NFKBIA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    114217931 (NFKBIA)
   05135 Yersinia infection
    114217931 (NFKBIA)
   05134 Legionellosis
    114217931 (NFKBIA)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    114217931 (NFKBIA)
   05140 Leishmaniasis
    114217931 (NFKBIA)
   05142 Chagas disease
    114217931 (NFKBIA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    114217931 (NFKBIA)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    114217931 (NFKBIA)
   04931 Insulin resistance
    114217931 (NFKBIA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:eju03000]
    114217931 (NFKBIA)
   04131 Membrane trafficking [BR:eju04131]
    114217931 (NFKBIA)
Transcription factors [BR:eju03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Ankyrin only
    114217931 (NFKBIA)
Membrane trafficking [BR:eju04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    114217931 (NFKBIA)
SSDB
Motif
Pfam: Ank Ank_2 Ank_3 Ank_5 Ank_4 ANK_LRRK2 TBC2_C
Other DBs
NCBI-GeneID: 114217931
NCBI-ProteinID: XP_027970675
LinkDB
Position
Unknown
AA seq 358 aa
MFQPAEHAQDWAMDGPRDALKKERLLDDRHDSGLDSMKDEDYEQLVKELREIRLEPQEAP
RGAEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDLAFLNFQNNLQQTPLHLAVI
TNQPEIAEALLEAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQTCRTQHLYSILQATN
YNGHTCLHLASIHGYLGIVELLVSLGADVNAQVSASCLQTECIKAARPSLIRLHVLLLQA
EIPNSAINISNSFWFQEPCNGRTALHLAVDLQNSDLVSLLLKCGADVNRVTYQGYSPYQL
TWGRPSTRIQQQLGQLTLENLQLLPESEDEESYDTESEFTEDELPYDDCVLGGQRLTL
NT seq 1077 nt   +upstreamnt  +downstreamnt
atgtttcagcccgccgagcacgcccaggactgggccatggacggtccccgggacgcgctc
aagaaggagcggctgctggacgaccgccacgacagcggcctggactccatgaaggacgag
gactacgagcagttggtgaaggagctgcgggagatccgcctggagccgcaggaggcgccg
cgcggcgccgagccctggaagcagcagctcaccgaggacggagactcgttcctgcacttg
gccatcatccatgaagagaaggcactgaccatggaagtgatccgccaagtgaagggcgac
ctggccttcctcaacttccagaacaacctgcagcagactccactccacttggctgtgatc
accaaccaaccagaaattgctgaggcacttctggaagctggctgtgatcctgagctccga
gactttcgaggaaatacccccctacaccttgcctgtgagcaaggctgcctggctagtgtg
ggagtcctgactcagacctgcaggacccagcacctctactccatcctccaggccaccaac
tacaatggtcacacgtgtctacacttagcctctatccatggctacttgggcatcgtggag
cttttggtgtctttgggtgctgatgtcaatgctcaggtgagtgcttcatgtctccagacg
gaatgcatcaaggctgcaaggccctccttaataagacttcacgtgctcttgttacaagca
gaaattccaaactcagccataaacatctcaaattccttttggtttcaggagccctgtaat
ggccgaaccgccctgcatcttgcagtggacttgcagaattctgatctcgtgtcactcttg
ttgaagtgtggggctgatgtcaacagagtgacctaccagggctactccccataccagctc
acctggggccgcccaagcacgcggatacagcagcagctgggccagctgaccctcgaaaac
cttcagctgctgccagagagcgaggatgaggagagctacgacacggagtcagagttcaca
gaggacgagctgccctatgatgactgtgtgcttggaggccagcgcctgacgttatga

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