Eumetopias jubatus (Steller sea lion): 114218318
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Entry
114218318 CDS
T07240
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
eju
Eumetopias jubatus (Steller sea lion)
Pathway
eju00230
Purine metabolism
eju00670
One carbon pool by folate
eju01100
Metabolic pathways
eju01523
Antifolate resistance
Module
eju_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
eju00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
114218318 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
114218318 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
114218318 (GART)
Enzymes [BR:
eju01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
114218318 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
114218318 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
114218318 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
ATP-grasp_3
ATP-grasp_4
Dala_Dala_lig_C
Sacchrp_dh_NADP
RimK
ATP-grasp_5
Motif
Other DBs
NCBI-GeneID:
114218318
NCBI-ProteinID:
XP_027971124
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAAQVLVIGSGGREHTLAWKLAQSNHVKHVLVAPGNAGTACLEKISNTAISVNDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TARWRAFTKPEEACSFIMSADFPALVVKASGLAAGKGVIVAKSTEEACRAVQEIMQDRAY
GAAGETIVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDHGPNTGGMGAYCPAP
QVSKDLFLKIKNIVLQRTVDGMQQEGMPYTGVLYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWHENRTAITVVMASKGYPGDHTKGVEITGFPEA
QALGLEVFHAGTALKDGKVVTNGGRVLTVTAIQENLILALEEAKKGLATIKFEGAIYRKD
IGYRAVAFLQQPRGLTYKESGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLNTTEAVVAGIARACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDVVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPEGCGDQTLGDLLLTPTR
IYSHSLLPVLRAGHIKAFAHITGGGLLENIPRVLPQKFGVDLDAQTWRVPRIFSWLQQEG
NLSEEEMARTFNCGIGAALVVSKDLTEQILRDIKQHKEEAWVIGKVVAWPEGSPRVKVKN
LIKTMQINGSVLENGTLKNHFSVQTKKARVAVLISGTGSNLQALIDSTREPSSCAHIVVV
ISNKAAVAGLDKAERAGIPTRVINHKLYKSRVEFDTTIDQVLEEYSTDIVCLAGFMRILS
GPFVRKWDGKMLNIHPSLLPSFKGSNAHEQALEAGVTVTGCTVHFVAEDVDAGQIILQES
VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGAVQLGENGKIRWVTEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccaagtacttgtaattggcagtggaggaagggaacacacactggcctggaaa
cttgcacagtctaatcatgtcaaacatgtgttggttgccccaggaaatgcaggcactgcc
tgcttggaaaagatttcaaatactgccatctcagtcaatgaccacactgcccttgctcag
ttctgcaaagatgagaaaattgaattcgtagttgttggaccagaggcacctctggctgct
ggaattgttgggaacctgacatctgcaggagtccgatgttttggtcccactgcagaagca
gctcagttagagtccagcaagagatttgccaaagagtttatggaccgacatggaatccca
actgcacggtggagagctttcaccaaacctgaagaagcctgcagctttataatgagtgca
gacttccctgctttagttgtgaaggccagtggtcttgcggctggaaaaggggtgattgtt
gccaagagcacagaagaggcctgcagggctgtacaggagatcatgcaggatagagcttat
ggagcagctggagaaacaattgtcattgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggaaggaccgtggcccccatgcccccagcacaagaccataagcga
ttgctggagggagatcatggccccaacacagggggaatgggagcctactgtccagcacct
caggtttctaaggatttgttcctgaaaataaaaaatatcgttcttcagaggacagtggat
ggcatgcagcaggagggtatgccatacacaggtgttctctatgctggtataatgctgacc
aaggatggcccaaaagttctggagtttaattgccgtttcggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgatctttatgaagtgatccagtctaccttggatggcctg
ctgtgcacatctctgcctgtttggcatgaaaaccgcactgccataactgtcgtgatggca
agtaaaggctatccaggagaccacaccaagggtgtggagataacaggatttcctgaagct
caagctttaggactggaggtgttccacgcaggcactgccctgaaagatggcaaagtggtg
actaatgggggtagagtccttacggtaacagcaattcaggaaaatctcatcttggccctt
gaagaagccaagaaaggactagctactataaaatttgagggagccatttacaggaaggac
attggctatcgtgccgtagcttttctccagcagcccaggggcctgacttacaaggaatct
ggggtagacattgcagctggaaatatgctggtcaagaaaattaaacctttagcaaaagct
acctccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctcttctggcaagtggaacagatggtgttggaactaaactg
aagattgcccaacagtgtaataaacatgataccattggtcaagatttggttgcaatgtgt
gtcaatgacattctggcccaaggggcagagcctcttttcttcctcgattacttttcctgt
ggaaaacttgacctcaatacaactgaagctgttgttgctggaatcgccagagcttgtgga
aaagctggatgtgctctccttggaggtgaaactgcagaaatgcccgacatgtatcctcca
ggagaatatgacctagctggttttgctgttggtgccatggagcgggatcagaaacttcct
cacctggaaagaatcactgaaggggatgttgttattggaatagcttcatctggtcttcac
agcaatgggttcagccttgtaaggaaaattgtagcaaaatcttccctccagtactcgtct
ccagcacctgaaggctgtggtgaccagaccttaggggacttacttctcactccaaccaga
atctacagccattcactgctacctgtcctacgtgcaggacacatcaaggcctttgcccat
attactggtgggggattgctagaaaacatccccagagtccttcctcagaagtttggggtg
gatttagatgcccagacctggagggttcccaggatcttctcatggttacagcaggaagga
aacctctctgaggaagagatggccagaacatttaactgtgggattggggctgccctcgtg
gtatcaaaggatctgacagagcagattctgagggatattaagcagcacaaggaagaagca
tgggtgattggcaaggtggttgcatggcctgaaggttctcctcgtgtgaaagtgaagaat
ctgataaaaaccatgcaaataaatgggtcagtattggagaatggcaccctgaaaaatcat
ttctctgtccaaacaaaaaaggcaagagtggctgttttaatatctggaacaggatcaaac
ctgcaagctctcatagacagtacaagggagccaagtagctgtgcacacattgttgttgtt
atctctaacaaagccgcagtggctggtttagataaagccgaaagagccggaattcccacc
agagtaattaatcataaattatataaaagtcgtgtagaatttgacaccacaattgaccaa
gtccttgaagagtactccacagacatagtctgtcttgcaggattcatgagaattttatcc
ggcccctttgtcaggaaatgggatgggaagatgctcaacatccacccatccttgctgcct
tcttttaagggttcaaatgcccacgagcaagccctagaagccggggtcacagtcactggg
tgtactgtgcactttgtagctgaagatgtagatgctggacaaattattttacaagaatct
gttccagtgaagagaggtgacactgttgcaactctgtctgaaagagtgaaattagcagag
cacaaaatatttcctgcagccctccagctggtggccagtggagctgtacagcttggagaa
aacggcaagattcgttgggtcacagaagagtga
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