| Entry |
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| Symbol |
ABCC1
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| Name |
(RefSeq) multidrug resistance-associated protein 1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
eju Eumetopias jubatus (Steller sea lion)
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| Pathway |
| eju04977 | Vitamin digestion and absorption |
| eju04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:eju00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
114219840 (ABCC1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
114219840 (ABCC1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
114219840 (ABCC1)
04981 Folate transport and metabolism
114219840 (ABCC1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
114219840 (ABCC1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
114219840 (ABCC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:eju02000]
114219840 (ABCC1)
Enzymes [BR:eju01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
114219840 (ABCC1)
Transporters [BR:eju02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
114219840 (ABCC1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1541 aa
MLPDIPPCTGQPHNRIVWFQMSAVPKAWDVTWNTSNPDFTKCFQNTFLMWVPCSYLWVCF
PFYFLYLSRHDRGYIQMTYLNKTKTALGFLLWIVCWADLFYSFWERSWGKFLAPVFLVSP
TLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALLCALAILRSKIMTALKEDAEINVF
RDVTFYIYFSLVLMQLGLSCFSDRPPLFSETIHDPNPCPESSASFLSRVTFWWITGLMVR
GYRQPLESTDLWSLNKEDTSEQVVPVLVKNWKKECAKSKRQQAKMAYSSKDSAKPKGGSQ
VDVNEEAEVLIVKSPQKEREPSLFKVLYKTFGPYFLMSFLFKALHDLMMFAGPEILKLLI
NFVNDQKAPDWQGYFYTALLFVSACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVI
TNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGV
AVMILMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLA
IRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTIDKNNILDAQKAFVSLALFN
ILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPIKDGGGANSITVKNAT
FTWARSDPPTLSGITFSIPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAY
VPQQAWIQNDSLRGNILFGRQLQERYYKTVIEACALLPDLEILPSGDRTEIGEKGVNLSG
GQKQRVSLARAVYCDSDIYLFDDPLSAVDAHVGKHIFENVIGPKGMLRSKTRLLVTHSIS
YLPQVDVIIVMTGGKISEMGSYQELLARDGAFAEFLRTYASTEQERAEPDDGLTSVSSPG
KEVKQMENGMLVTDVTGKQLQRQLSNSSSYSGDISRHRTSTAELQKAGAENEDAWKLVEA
DKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHIAALASNYWLSLWTDDPIVNGTQE
HTKVRLSVYGALGISQGISVFGYSMVVSIGGILASRRLHLDLLQNVLRSPMSFFERTPSG
NLVNRFSKELDTVDSMIPQVIKMFMGSLFNVMGACIIILLATPIAAIIIPPLGLIYFFVQ
RFYVASSRQLKRLESVSRSPVYSHFSETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYY
PSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRM
SSEMETNIVAVERLKEYSETEKEAPWQVQEMTPPSTWPQVGRVEFRDYGLRYRENLDLVL
KHINVTIDGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIVIDDINIAKIGLHDLRFKI
TIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLNHECAEGGENL
SVGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNT
IMDYTRVIVLDKGEIRECGQPSDLLQQRGLFYSMAKDAGLV |
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| NT seq |
4626 nt +upstreamnt +downstreamnt
atgctgccggacatcccgccatgcacaggacagcctcacaacagaattgtctggtttcag
atgtcagctgtgccaaaggcgtgggacgtcacgtggaacaccagcaaccccgacttcacc
aagtgctttcagaacacgttcctcatgtgggtgccttgttcttacctctgggtctgcttc
cccttctacttcctctatctctcacgccatgaccggggctacattcagatgacctatctc
aacaaaaccaaaactgccttgggatttttgctgtggatcgtctgctgggcagacctcttc
tactctttctgggaaagaagttggggcaaattcctggccccagtgtttctggtcagccca
accctcttgggcatcaccatgctgcttgctacctttttgattcagctcgagagaaggaag
ggagtccagtcctcggggatcatgctcactttctggcttgtagccctactgtgtgccctt
gctatcttgagatccaaaatcatgactgccttaaaagaggatgctgaaatcaacgtgttt
cgcgatgtcactttctacatttacttttccctcgtgctgatgcagcttgggctgtcctgt
ttctcggaccgaccgcccctgttctctgaaaccatccacgaccccaatccctgcccggaa
tccagcgcctccttcctttccagagtcaccttctggtggatcacagggctgatggtccgg
ggctaccgccagcccctggagagcactgacctctggtccctgaataaggaggacacatca
gaacaagttgtgcctgttttggtaaagaactggaagaaggagtgtgccaaatccaaaagg
cagcaggcaaagatggcgtactcctccaaggactccgccaagccgaaagggggctcgcag
gtggatgtgaatgaggaggctgaggttttgattgtcaagtccccccagaaggagcgggag
ccgtctctgttcaaggtgttatacaagacctttggaccctacttcctcatgagcttccta
ttcaaggccctccacgacctgatgatgtttgcaggcccagagatcctaaaattgctcatc
aacttcgtgaacgatcagaaggccccggactggcagggctacttctacaccgcgctgctc
ttcgtcagcgcctgcctccagaccctcgtcctgcaccagtacttccacatctgcttcgtc
agcggcatgaggatcaagacggccgtcatcggcgccgtctaccggaaggccttggtgatc
accaactccgccagaaaatcctccaccgtcggggagattgtcaacctcatgtctgtggac
gcccagaggttcatggacctggccacgtacattaacatgatctggtcagctcctctgcaa
gtcatccttgctctctacctcctgtggctgaacctgggtccatccgtcctggccggggtg
gctgtgatgatcctcatggttcccctcaatgctgtgatggccatgaagaccaagacctac
caggtggcgcacatgaagagcaaagacaatcggattaagctgatgaacgagattctcaat
gggatcaaagtgctcaagctttatgcctgggaactggccttcaaagacaaggtgctggcc
atcaggcaggaggagctgaaggtgctcaagaaatcggcctacctggcagctgtgggaacc
ttcacctgggtctgcacacctttcctggtggccctgtctacctttgctgtctacgtgacc
atcgacaagaacaacatcctggatgcccagaaagcttttgtgtccttggccttgttcaac
atcctccgatttcccctgaatattctccccatggtcatcagcagcatcgtgcaggcgagt
gtctccctcaaacgcctcaggatctttctgtctcacgaggagctggagcctgacagcatc
gagcgaaggcccatcaaagacggcgggggcgcaaacagcatcactgtgaagaacgccacg
ttcacgtgggccaggagcgaccctccgacgctaagtggcatcacgttctccattccggaa
ggttccttggtggccgtcgtgggccaggtgggctgtggaaagtcgtctctgctctcagca
ctcctggccgagatggacaaggtggaggggcacgtggctatcaagggttcagtggcctac
gttccgcagcaggcctggattcagaatgattccctccgaggaaacatcctttttggccgc
cagctacaggaacggtattataagaccgtcatcgaggcctgtgccctcctcccagatctg
gaaatcctgcccagtggggaccggacagagattggtgagaagggcgtgaacctgtctggg
ggccagaagcagcgagtgagcctggcccgggccgtgtactgtgactccgacatctacctc
ttcgatgaccccctgtcggcggtggatgcccacgtgggcaaacacatatttgaaaatgtc
attggccccaaggggatgctgaggagcaagacgcggctcctggtcacgcacagcatcagc
tacctgccccaggtggatgtcatcatcgtcatgactggcggcaagatctcggagatgggc
tcctaccaggagctgctagcccgggacggcgccttcgccgagttcctgcgcacgtatgcc
agcaccgagcaggagcgggccgagccggatgacgggttaacaagtgtcagcagcccaggg
aaggaggtgaagcagatggagaatggcatgctggtgaccgatgtcacggggaagcagctg
cagagacagctcagcaactcctcctcttacagcggggacattagccgccaccgcaccagc
acggccgagctgcagaaagccggggccgagaacgaggacgcgtggaagctggtggaggcg
gacaaggcgcaaacagggcaggtcaagctgtccgtgtactgggactacatgaaggcgatc
ggacttttcatctcctttctgagcatcttccttttcctgtgtaaccacattgctgctctg
gcctctaactactggctcagcctctggactgatgaccccatcgtcaatgggacccaggaa
cacactaaagtccggctgagcgtctatggagccctgggcatttcacaaggtatctctgtg
ttcggctactccatggtggtgtccatcggggggatcttggcttcccgccgcctgcacctg
gacctgctacagaacgtcctccggtcacccatgagcttcttcgagcggacccccagcggg
aacctggtgaaccgcttctctaaggagctggacacggtggactcgatgatcccgcaggtc
atcaagatgttcatgggctccctgttcaatgtcatgggcgcctgcatcatcatcctgctg
gccactcccattgctgccatcatcatcccgccactgggcctcatctacttcttcgtccag
aggttctacgtggcctcatcccggcagctgaagcgcctcgagtcggtgagccgctccccg
gtctactcccacttcagtgagaccttgctgggcgtcagcgtcatccgcgccttcgaggag
caggaacgcttcatccaccagagtgacctgaaggtggatgagaaccagaaggcctattac
cccagcatcgtggccaacaggtggctggcggtgcggctggagtgtgtaggcaactgcatc
gtcctgttcgccgccctgttcgccgtgatttccagacacagtctcagcgctggcttggtg
ggcctgtctgtgtcgtactcgctgcaggtcaccacgtacttgaactggctggttcgcatg
tcgtccgagatggagaccaacattgtggcggtggagaggctgaaggagtattcagaaacg
gagaaggaggctccttggcaagtccaggaaatgactccgcccagcacctggcctcaggta
ggccgagtagaattccgtgactacggcctgcgataccgagaaaacctggacttggttctc
aagcacatcaacgtcaccatcgatggaggggaaaaggtcggcatcgtggggcggacagga
gctgggaagtcgtccctgaccctgggcttgtttcggatcaatgagtctgctgaaggggag
atcgttattgatgacatcaacattgccaagatcggcctgcacgatctgcgcttcaagatc
accatcatcccgcaggaccctgttttgttctcgggttccctccgcatgaacctggacccg
ttcagccagtactcagatgaggaagtctggacgtccctggagctggctcacctgaaggac
ttcgtgtccgcccttcccgacaagctgaaccacgagtgtgcggaaggcggggagaacctg
agcgtcgggcagcgccagcttgtgtgcctggcccgggctctgctgcggaagaccaagatc
cttgtgttggacgaggccacggcggccgtggacctcgaaacggacaacctcatccagtcg
accatccggacgcagtttgaggactgcaccgtgctcaccattgcacaccggctcaacacc
atcatggactacacgagggtcatcgtcctggacaagggagagatccgggagtgcggccag
ccctccgacctcctccagcagagaggtcttttctacagcatggccaaagatgctggcctg
gtgtga |
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