Eumetopias jubatus (Steller sea lion): 114220439
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Entry
114220439 CDS
T07240
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2 isoform X1
KO
K04688
ribosomal protein S6 kinase beta [EC:
2.7.11.1
]
Organism
eju
Eumetopias jubatus (Steller sea lion)
Pathway
eju01521
EGFR tyrosine kinase inhibitor resistance
eju01522
Endocrine resistance
eju04012
ErbB signaling pathway
eju04066
HIF-1 signaling pathway
eju04140
Autophagy - animal
eju04150
mTOR signaling pathway
eju04151
PI3K-Akt signaling pathway
eju04152
AMPK signaling pathway
eju04211
Longevity regulating pathway
eju04213
Longevity regulating pathway - multiple species
eju04350
TGF-beta signaling pathway
eju04371
Apelin signaling pathway
eju04666
Fc gamma R-mediated phagocytosis
eju04714
Thermogenesis
eju04910
Insulin signaling pathway
eju04931
Insulin resistance
eju05163
Human cytomegalovirus infection
eju05165
Human papillomavirus infection
eju05170
Human immunodeficiency virus 1 infection
eju05200
Pathways in cancer
eju05205
Proteoglycans in cancer
eju05207
Chemical carcinogenesis - receptor activation
eju05210
Colorectal cancer
eju05212
Pancreatic cancer
eju05221
Acute myeloid leukemia
eju05224
Breast cancer
eju05225
Hepatocellular carcinoma
eju05226
Gastric cancer
eju05231
Choline metabolism in cancer
eju05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
eju00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
114220439 (RPS6KB2)
04350 TGF-beta signaling pathway
114220439 (RPS6KB2)
04371 Apelin signaling pathway
114220439 (RPS6KB2)
04066 HIF-1 signaling pathway
114220439 (RPS6KB2)
04151 PI3K-Akt signaling pathway
114220439 (RPS6KB2)
04152 AMPK signaling pathway
114220439 (RPS6KB2)
04150 mTOR signaling pathway
114220439 (RPS6KB2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
114220439 (RPS6KB2)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
114220439 (RPS6KB2)
09152 Endocrine system
04910 Insulin signaling pathway
114220439 (RPS6KB2)
09149 Aging
04211 Longevity regulating pathway
114220439 (RPS6KB2)
04213 Longevity regulating pathway - multiple species
114220439 (RPS6KB2)
09159 Environmental adaptation
04714 Thermogenesis
114220439 (RPS6KB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
114220439 (RPS6KB2)
05205 Proteoglycans in cancer
114220439 (RPS6KB2)
05207 Chemical carcinogenesis - receptor activation
114220439 (RPS6KB2)
05231 Choline metabolism in cancer
114220439 (RPS6KB2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
114220439 (RPS6KB2)
09162 Cancer: specific types
05210 Colorectal cancer
114220439 (RPS6KB2)
05212 Pancreatic cancer
114220439 (RPS6KB2)
05225 Hepatocellular carcinoma
114220439 (RPS6KB2)
05226 Gastric cancer
114220439 (RPS6KB2)
05221 Acute myeloid leukemia
114220439 (RPS6KB2)
05224 Breast cancer
114220439 (RPS6KB2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
114220439 (RPS6KB2)
05163 Human cytomegalovirus infection
114220439 (RPS6KB2)
05165 Human papillomavirus infection
114220439 (RPS6KB2)
09167 Endocrine and metabolic disease
04931 Insulin resistance
114220439 (RPS6KB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
114220439 (RPS6KB2)
01522 Endocrine resistance
114220439 (RPS6KB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
eju01001
]
114220439 (RPS6KB2)
Enzymes [BR:
eju01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
114220439 (RPS6KB2)
Protein kinases [BR:
eju01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
114220439 (RPS6KB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Kinase-like
Pkinase_fungal
ABC1
Seadorna_VP7
Motif
Other DBs
NCBI-GeneID:
114220439
NCBI-ProteinID:
XP_027974124
LinkDB
All DBs
Position
Unknown
AA seq
481 aa
AA seq
DB search
MAAVFDLDLETEEGSEGEPELSPSDVCPLAESRAAGLEPVGHCEEVELTETSVNLGPERI
GPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNI
LESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLAL
GHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILV
RSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLTLPPYLTPDARDLVKK
FLKRNPSQRIGGGLGDAADVQRHPFFRHIIWDDLLARRIDPPFRPSLQSEEDVSQFDTHF
TRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRTPV
SPLKFSPFEGFRPSSGSLEPMEPPLPPLLPPPPPPSSTAPLPIRPPSGTKKSKRGRGRPG
R
NT seq
1446 nt
NT seq
+upstream
nt +downstream
nt
atggcggccgtgtttgacctggacctggagacggaggaaggcagcgagggcgagccagag
ttgagcccctcggacgtgtgtccccttgccgagtcgagggcggctggcctggagcctgtg
ggacactgtgaggaggtggagctgactgagaccagtgtgaatttgggccctgagcgcatc
ggaccccactgctttgagctgctgcgtgtgctgggcaaggggggctatggcaaggtgttc
caagtgcgaaaggttcagggcaccaacttgggcaaaatatatgccatgaaagtcctgagg
aaggccaaaattgtgcgcaacgccaaggacacagcacacacgcgggctgaacggaacatt
ctagagtcagtgaagcaccccttcattgtggaactggcctatgccttccagactggtggc
aaactctacctcatcctcgagtgtctcagtggcggtgagctcttcacgcatctggagcga
gagggcatcttcctggaagacacggcctgtttctacctggcagagatcacactggccctg
ggccatctccactcccaaggcatcatctaccgggacctcaaacctgagaacatcatgctc
aacagccagggccacatcaaactgacagactttggactctgcaaggagtcgatccacgag
ggcgccgtcacccatactttctgtggcaccattgagtacatggcccctgagattctggta
cgcagtggccacaaccgggcggtggactggtggagcctgggggccctgatgtatgacatg
ctcactggatcgccacccttcactgcagagaaccggaagaaaaccatggacaagatcatc
aaagggaagctgacgctgcccccctacctcaccccggatgcccgggaccttgtcaaaaag
tttctgaagcggaatcccagccaacggatcgggggtggccttggggatgctgctgatgtg
cagaggcaccccttctttcggcacattatttgggacgacctcctggctcgccgcatcgac
ccccctttcaggccctctctgcagtcagaggaggatgtgagccagtttgacacccacttc
acgcggcagacgccagtggacagtcccgatgatacggccctcagtgagagcgccaaccag
gccttcctgggcttcacatatgtggcaccctccgtcctggacagcatcaaggagggcttc
tccttccagcccaagctgcgctcccccaggcgcctcaacagcagtccccggaccccggtc
agccccctgaagttctcgcccttcgagggattccggcccagctctggctcactggagccc
atggagccccctctacctcctctcctgccgccaccgccaccaccctcgagcactgccccc
ctccccatccgacccccctcggggaccaagaagtctaagaggggccgtgggcgcccaggg
cgctag
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