Eumetopias jubatus (Steller sea lion): 114223582
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Entry
114223582 CDS
T07240
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
eju
Eumetopias jubatus (Steller sea lion)
Pathway
eju00010
Glycolysis / Gluconeogenesis
eju00020
Citrate cycle (TCA cycle)
eju00620
Pyruvate metabolism
eju00785
Lipoic acid metabolism
eju01100
Metabolic pathways
eju01200
Carbon metabolism
eju01210
2-Oxocarboxylic acid metabolism
eju04066
HIF-1 signaling pathway
eju04922
Glucagon signaling pathway
eju05230
Central carbon metabolism in cancer
eju05415
Diabetic cardiomyopathy
Module
eju_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
eju00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
114223582 (PDHA1)
00020 Citrate cycle (TCA cycle)
114223582 (PDHA1)
00620 Pyruvate metabolism
114223582 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
114223582 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
114223582 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
114223582 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
114223582 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
114223582 (PDHA1)
Enzymes [BR:
eju01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
114223582 (PDHA1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
114223582
NCBI-ProteinID:
XP_027978350
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLRYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRAGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctcgccgctgtctctcgcgtgttgtcgggcgtcgcccagaagccggca
agcagagtgctcgtggcctcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgcgatcttcatcggctagaagagggccctcctgtcaccacagtgctcaccagggaggac
gggctcaggtactacaggatgatgcagactgttcgccggatggagttaaaggcagatcag
ctgtataaacagaaaatcattcgtggtttctgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggccggcataaatcccacagaccatcttatcacagcctatcgggct
catggctttacctttacccgtggactttctgtccgagaaattctcgcagagcttacagga
cgaagaggaggctgtgctaaaggaaaaggtggatcgatgcatatgtatgccaagaacttc
tacgggggcaatggcatcgttggagctcaggtgcccctgggagcagggattgcgctggcc
tgtaagtacaacggaaaggacgaggtctgcttgactctgtatggcgacggtgctgccaat
cagggtcagatatttgaagcttacaacatggcagctttgtggaaattgccatgtattttc
atctgtgagaataaccgctatggaatgggaacgtctgttgagagagcagcggctagcact
gattactacaagagaggcgacttcattcctgggctgagggtggatggaatggatatcttg
tgtgtccgggaggcaacaagatttgcagctgcttactgtagagctggaaaggggcccata
ctgatggagctacagacttaccgttaccatggacacagcatgagcgaccccggcgtcagt
taccgaacacgagaagagattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaacagcaatctggccagtgttgaagaattaaaggaaattgatgtt
gaagtgaggaaagaaattgaggatgctgcccagtttgccactgctgatcctgaaccgcct
ttggaagaactaggctatcacatttacagcagcgatccaccttttgaagttcggggtgca
aatcagtggatcaagtttaagtccatcagttaa
DBGET
integrated database retrieval system
