Enterococcus lactis: I4Q40_00970
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Entry
I4Q40_00970 CDS
T07069
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
elac
Enterococcus lactis
Pathway
elac00300
Lysine biosynthesis
elac00550
Peptidoglycan biosynthesis
elac01100
Metabolic pathways
elac01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
elac00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
I4Q40_00970
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
I4Q40_00970
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
I4Q40_00970
Enzymes [BR:
elac01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
I4Q40_00970
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF3323
Motif
Other DBs
NCBI-ProteinID:
QPL60262
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All DBs
Position
193050..194402
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AA seq
450 aa
AA seq
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MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGTRDGHEFIQQAITNGAS
ASFWSLPVEQAPKDFPVIPVADPLKAMQQLATYYLEKVGAEVVAITGSNGKTTTKDLTAS
VLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMGMDHANEITELSLMAQPKAAA
ITMIGEAHIENLGSREGIAKAKMEITDGLVPDGLLVVPADEPLLTPLTATLVQTVTTFGI
GNGDVHAEVTAEGKAQTDFVVEGETFTIPLPGSYNVTNALIAYTIGRFFELSIPEIRQGL
AHVSITQNRTEWLTAGNGAAILSDVYNANPTAMGLVLDTFKNLPTKGRRIAVLADMLELG
KDSLNMHAQMSEHIDPEKFAMIFLYGEQMHALKEDLNQKYPQLPVFYFEKEKNKLIEAVK
QTLESTDSIMLKGSNSMGLFEVVEQLQQMK
NT seq
1353 nt
NT seq
+upstream
nt +downstream
nt
atgaatctaacaatacaagaaattgcacaagccgtgggcagcgaatgctctgcactgaca
aagattaccaatgtcgaatttgacagccggaagataaccgaaggaagtttattcgttcct
cttgccggtacgcgagatggacatgaatttatccagcaagcgatcacaaacggcgcatct
gcttcattttggagcttgcctgttgaacaagcaccaaaagattttccagttatccctgta
gcagatcctttgaaagccatgcagcaattggcaacctattacttggaaaaagtaggcgca
gaagtcgttgcaattacaggaagcaatggtaaaaccaccacgaaagatctaaccgcgtct
gtcttgtctgaaaaatacaaaacatataagacgcaaggaaattacaacaataatattggt
cttccttacacgattttgcacatgccgcaagatacagaaaaaatcgttttggaaatgggc
atggatcacgccaatgaaatcacagaactttcacttatggctcaaccaaaagctgcagca
atcacaatgatcggtgaagcacacatagaaaatcttgggtcgcgagaaggaatcgctaaa
gccaaaatggaaatcactgacggacttgtaccagacggattactcgttgtgcccgcagat
gaaccgttgctgacacctttaacggcaacattagtacaaacagtcacaacattcggtatt
ggaaatggcgatgttcatgcagaagtgacagcagaaggaaaagcgcaaaccgattttgta
gtagaaggagaaacatttacgatcccgctgcctggaagttataatgtaacgaatgctttg
attgcgtatacgatcgggcgcttctttgaactgtccatacctgagatacgccaagggctc
gctcatgtttctatcacacaaaatagaactgaatggctaacggcaggaaatggtgcagct
attttgagcgatgtctacaatgcaaatccaacagccatgggactagtattagatactttt
aaaaatctgccaacaaaagggcgcagaatcgctgtgttagcagatatgctggaattaggg
aaagattcattaaacatgcatgcgcaaatgagtgaacatatcgatcctgagaaatttgcc
atgattttcttgtacggggaacaaatgcatgcattaaaagaagacttgaatcaaaaatat
ccgcaactacctgtgttctattttgaaaaagaaaagaataaattgattgaagctgtcaaa
caaactcttgaatcaacagacagtattatgctgaaaggcagcaacagcatgggcttattc
gaagtagtagaacagcttcagcaaatgaaataa
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