Enterococcus lactis: I4Q40_09130
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Entry
I4Q40_09130 CDS
T07069
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
elac
Enterococcus lactis
Pathway
elac00300
Lysine biosynthesis
elac00550
Peptidoglycan biosynthesis
elac01100
Metabolic pathways
elac01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
elac00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
I4Q40_09130
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
I4Q40_09130
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
I4Q40_09130
Enzymes [BR:
elac01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
I4Q40_09130
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QPL59384
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Position
complement(1887850..1889340)
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AA seq
496 aa
AA seq
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MTSIHSLLVDMDGHYLKKYGDLDRNIQDVEYFSGHLKRNMDYSDTMFVCVSPERRSYVNR
KVVRWRDGNEQIIGKENWFGVIVTEKPIMDPSVTTPQFIVEDSWKFLLELSAKLRSCFVN
PVVAITGSAGKTSTRMMITHLLQEEKVLENRGNHNVRFAVPLYMSKLLSNPDVLNLEVSV
NALNSYDTGSMSNLIQPDIAIVTSIGEAHLSSLKNTKGVAVHKAKIFEGLKQDGIAIING
DIGKEEFSILVSAAEKRTSKIVVYSLHDASRGVFVKQISQKREYCEVLVSFFGEDILLKL
AVSSEGMIANSLAALIVAKELKKEISPYIKKFETFKPLPKILERTIYTSETGTDFTFIDD
THNASLPSMKNAINYFDGIQPFYKGNKVLILGQIADLGDSTKQIHRFVQEELNQSAATHI
YGYGEHFKLLFEEGQKIDDRLQWFDSLQELCNDLETKLIEDSLVLAKGSVTGSDFHEIGK
YVRQIGNKHNMKSQTL
NT seq
1491 nt
NT seq
+upstream
nt +downstream
nt
atgacttctatacattcattattagttgatatggatggccattatttaaagaaatatgga
gatttagatagaaatatccaagatgttgaatatttctcaggccacttaaaacgaaacatg
gattattctgatacgatgtttgtttgtgtttcgccagaaagaaggagttacgtcaatcga
aaggtcgtgagatggcgagatggaaatgaacaaatcatcggaaaagaaaattggtttggt
gtgatcgttactgaaaaaccaatcatggatccgtcagtgacgacaccacagttcatcgta
gaagacagttggaaatttttattggaattatccgcgaaattgcggtcctgttttgtaaat
ccggttgttgcgattaccgggtcagcagggaagacttctacgcgaatgatgatcactcat
ttgcttcaagaagagaaagttttggaaaacaggggaaaccacaacgttcggtttgctgtt
cctttatacatgagtaaattactttctaatcctgatgtcttgaatcttgaagtttctgtc
aatgctttgaattcatatgatacagggtcgatgtctaatttgatacaaccagatattgct
attgtgacttcaattggagaagcacatcttagttctttaaaaaatacaaaaggagtagca
gtgcataaagcaaaaattttcgaaggcctgaaacaagatggaatcgccatcatcaatgga
gatataggaaaagaagaattttcaattttagtaagcgctgctgagaaaagaaccagcaaa
atagtggtctattcattacatgatgcttcaagaggtgtttttgtgaaacaaatctcacaa
aaaagagaatattgcgaagtcctagtttcttttttcggagaagatattttattgaaactt
gcagtttcttcagaagggatgatcgctaattcattggctgcgttgattgtagcaaaagaa
ctgaaaaaagagatctctccatatataaaaaaatttgagacattcaaaccactacctaag
atattggaacgtacgatttatacatcagaaacagggacagacttcacctttattgatgat
acgcataacgcttcattgccttccatgaaaaatgcaatcaattactttgatgggatacaa
ccattttataaaggaaataaagtcttgatacttggacaaatcgctgatttaggcgattca
acaaagcaaatccaccgctttgtacaagaggagttaaaccaatcggctgccacgcatatt
tatggttatggggaacattttaaattgctttttgaagaaggacagaaaatagatgatcgg
cttcaatggttcgattcacttcaggaattatgcaatgatctggaaacaaaactaatagaa
gacagtttagttttagcaaaaggatcagttactggaagtgattttcatgaaatcggcaaa
tatgtgcgtcagatcggaaacaagcataatatgaaaagtcagactttatag
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