KEGG   Enhydra lutris kenyoni (northern sea otter): 111146005
Entry
111146005         CDS       T05871                                 
Name
(RefSeq) 78 kDa glucose-regulated protein isoform X1
  KO
K09490  endoplasmic reticulum chaperone BiP [EC:5.6.1.10]
Organism
elk  Enhydra lutris kenyoni (northern sea otter)
Pathway
elk03060  Protein export
elk04141  Protein processing in endoplasmic reticulum
elk04156  Integrated stress response (ISR) signaling pathway
elk04612  Antigen processing and presentation
elk04918  Thyroid hormone synthesis
elk05012  Parkinson disease
elk05014  Amyotrophic lateral sclerosis
elk05020  Prion disease
elk05022  Pathways of neurodegeneration - multiple diseases
elk05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:elk00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03060 Protein export
    111146005
   04141 Protein processing in endoplasmic reticulum
    111146005
 09140 Cellular Processes
  09143 Cell growth and death
   04156 Integrated stress response (ISR) signaling pathway
    111146005
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    111146005
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    111146005
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    111146005
   05014 Amyotrophic lateral sclerosis
    111146005
   05020 Prion disease
    111146005
   05022 Pathways of neurodegeneration - multiple diseases
    111146005
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    111146005
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:elk03110]
    111146005
   04131 Membrane trafficking [BR:elk04131]
    111146005
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:elk04147]
    111146005
Enzymes [BR:elk01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.1  Enzymes altering polypeptide conformation or assembly
    5.6.1.10  non-chaperonin molecular chaperone ATPase
     111146005
Chaperones and folding catalysts [BR:elk03110]
 Heat shock proteins
  HSP70 / DNAK
   111146005
Membrane trafficking [BR:elk04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   ER-Golgi intermediate compartment (ERGIC) proteins
    111146005
 Autophagy
  ER-phagy
   ER stress-related proteins
    111146005
Exosome [BR:elk04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   111146005
  Exosomal proteins of other body fluids (saliva and urine)
   111146005
  Exosomal proteins of colorectal cancer cells
   111146005
SSDB
Motif
Pfam: HSP70 MreB_Mbl Hydantoinase_A FtsA FGGY_C DDR
Other DBs
NCBI-GeneID: 111146005
NCBI-ProteinID: XP_022357075
UniProt: A0A2Y9JH21
LinkDB
Position
Unknown
AA seq 654 aa
MKLSLVAAVLLLLGAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGDEEPADKDEL
NT seq 1965 nt   +upstreamnt  +downstreamnt
atgaagctgtccctggtggctgcggtgctgctgctgctcggcgcggcgcgggccgaggag
gaggacaagaaagaggacgtgggcacggtggtaggcatcgacctggggaccacctactcc
tgcgtcggggtgttcaagaacggccgcgtggaaatcatcgccaacgatcagggcaaccgc
atcacgccgtcttatgtggccttcactccggaaggggagcgtctgatcggcgacgcagcc
aagaaccagctcacctccaaccctgagaacacggtcttcgacgccaagcggctcatcggc
cgcacgtggaacgacccgtccgtgcagcaggacatcaagttcctgccgttcaaggtggtt
gagaagaagactaaaccatacattcaagttgatattggaggtgggcaaacaaagacattt
gctcctgaagaaatttctgccatggttctcaccaaaatgaaggaaactgcagaggcttac
ttgggaaagaaggtgacccatgcagttgttactgtaccagcctatttcaatgatgcccaa
cgacaggcaaccaaagatgctgggactattgctggattgaatgtcatgaggatcattaat
gagcctacagcagctgctattgcttatggcttggataagagggaaggggagaagaatatc
ctggtgtttgacctgggtggtggaactttcgatgtgtctcttctcaccattgacaatggt
gtcttcgaagtcgtagctactaatggagatactcatctgggtggagaagactttgaccaa
cgtgtcatggaacacttcatcaaactctacaaaaagaagactggcaaagatgttagaaaa
gataacagagctgtgcagaaactccggcgggaggtagaaaaggccaaacgggccctgtct
tctcaacatcaagcaagaattgaaattgagtctttctatgaaggagaagacttctctgag
actctgacacgggccaaatttgaagagctaaatatggacctgttccgttctaccatgaag
cctgtccagaaggtgctggaggattctgacttaaagaagtctgatattgatgaaattgtt
cttgttggtggctctactcgaatcccaaagattcagcaactggttaaagagttcttcaat
ggcaaggagccatcccgtggcatcaacccagatgaggctgtagcatatggtgctgctgtc
caggctggtgtcctctctggtgatcaagatacaggtgatctggtactgcttgatgtgtgt
ccccttacacttggtattgagactgtgggaggtgtcatgaccaaactgattccaaggaac
actgtggtgcccaccaagaagtctcagatcttttctacagcttctgataaccaaccaact
gttacaatcaaggtctatgaaggtgaacgaccccttacaaaagacaatcaccttctggga
acttttgatctgactggaattcctcctgctccccgtggggtcccacagattgaagttacc
tttgagatagatgtgaatggcattcttcgagtgacagccgaagacaagggtacaggcaac
aaaaacaagattacaattaccaatgaccaaaatcgcctgacacctgaagaaattgaaagg
atggttaatgatgctgagaagtttgccgaggaagacaaaaagctcaaggagcgcattgac
accaggaatgaattggaaagctatgcttattctctaaagaatcagattggagataaagaa
aagctgggaggtaaactctcctccgaagataaggagaccatggaaaaagccgtagaggaa
aagattgaatggctagaaagtcaccaagatgctgacattgaagatttcaaagctaaaaag
aaggaactagaagaaattgttcagccaattatcagcaaactctatggaagtgcaggccct
cccccaactggtgatgaggaaccagcagacaaagatgagttgtag

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