Enhydra lutris kenyoni (northern sea otter): 111146140
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Entry
111146140 CDS
T05871
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
111146140
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
elk03021
]
111146140
Enzymes [BR:
elk01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
111146140
5.6.2.5 RNA 5'-3' helicase
111146140
Transcription machinery [BR:
elk03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
111146140
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
nSTAND3
AAA_22
ResIII
SLFN-g3_helicase
Helicase_RecD
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
111146140
NCBI-ProteinID:
XP_022357260
UniProt:
A0A2Y9JHG2
LinkDB
All DBs
Position
Unknown
AA seq
2682 aa
AA seq
DB search
MSTCCWCTPGGISTVDFLQRYASRTHSGEFQTADEDLCYCLECVAEYHRARDDLPFLHEV
LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSILEKGKLILLPSHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQSDDDSVDPFWPALHCFMVILDRL
GSKVWGQRIDPIEAFQTIINNVSYNKEIQNIRNSSVRTKLEPESYSGDMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQTDAVCDKVTEFFLLILVSVIELHRHKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTTQETHELQTCLKQIIKNIKVKVP
QYNTFVDLSPACKSSPASYSKEENEQIDRKSNKDLPCLESSSPTFPKEPMKAETYQMQEN
ILIKASNTIEEDNEQNFIKDWKLEDHVPAESCIKKSSKNLFTEKGQDQVKRSTGKQKSVK
ENCTSRNDPERGCDRGIIMSTRLLTSSSTESLEKASTSTENFSFKDDALGKTSKSKTKAR
KDEICAKLSHVIKKQHRKGTLVSNTGNLEENLAVSNIDRFYSRKDSGGQKGDGFMHNLSL
DPNGILDDKNGEQKSQNSLLLKKKPLKSEELDVFSSHENSYQMQECHIDDKDLVSFTEVT
NTFVKKTSPFKDPVTVFESRDKESSKNSSPLSSHLREQALGLSPQSDTLTDSQVDRDLHK
LSLLAQASVIKFPSDSTQKSSCQLQRRVKDDRRCFLADQNNTGEACRGQIIIISDSDDDD
DDDEILGFERPIKQDKIGIKNECPEQHTSIASANVEKKLIKEEETKSLLQFEESDSQFFE
FESPCEVFSVWQDQEPDKNSVQENEKNSFSADIADITNDWGYETDYVSEEVIKKVAEGIE
KHTEPQSSISVGEIREIEVKKRKRKRFEKPMAEDRPRPSPSDRNEDQPDILNERSLTKND
FKSMDLRTSPSSSVQRDKDTTVALKKSSPKLRTYSRPIRRVPLSKTPKKAHSDTKKGQNK
SSNYISCRTTPAIVPPKKLRQCPEPTSKVEKLGLKKAPRRAFELSQRSLDYLVKLRRHGT
SVGVVDTRKKTKLISPQTLSVKNNKKLLTSQDLQLRRQMRSKSQKNRQGLSDYESKDTTR
AGPCAAQNSDILVPESDGSDYSYKGGTEAVANTTGKQSIKRVSSEPEPMKTKYVSQVTDD
TCLLSPCASVVLNGRIPTNEINVSASADPLGGSDPTVHRLELATLKDGELDSNSDTEDEN
IFLTQHNPEDMDLCSQMENGNEKLIEVIRGKDTAQVEEDSLSRHQLESWSSTKCKYKDCV
ETPKNQGEYCAKHCEAKAADEDVFRKPGLPLSASKPSRPSTAKIFSSSSTSRIANLSKSL
ESTPALPPALKNKSSGTQAVLKVPQPASVLSPKPVGEVKSLCNILHPQTPNNSNRQGYKL
TFGESKSFSASTPVNILLSSQSISDTFVKEVLKWKYEMFVNFDQCGPPASLCQSISRPVP
IRFQDCGDYFNVFFPLMILNTFETVAQEWISSPNKEKFYQLHLRKFPADYKKYWEFVVHL
EECELAKQLHPKENDLVFLIPERQNGENKDTERDHMEDLRDYHCAYVHKFRRTSVMRNGK
SECSLSIQIQDNLPVNLNELVKCIVISSLVTTQRKLKAMSLLSGRNQLARAVLNPNPMDF
CTKDLLTTTSERIITYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIV
GLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNP
LGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSHVQEMHRRKEFLDRQLDEL
SRQRALCRGGREMQRQELDEEIAKVSKERQELASKIKEVQGRPQKTQSIIILESHVICCT
LSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPT
VISMKAQEYGYDQSMMARFYKLLEDSVEHSVVGRLPVLQLTVQYRMHPDICLFPSGYVYN
KSLKTSRQTETSRCSSDWPFQPYLVFDVGDGSERRDNDSYVNVQEIKLVMEIIKLIKDKR
RDVTFRNIGIITHYKAQKMMIQKDLDKEFDRKGPAEVDTVDGFQGRQKDCVIVTCVRANT
AQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNHLIQDAQKRGAIIKTCDRN
YRHDAAKILKLKPVLQRSVTHPPAVVPEASRPPGGLPSSRLDSELAKTSFTSLYHTPSDS
KESAGTVTAKDPERPLIQDRLRDPRLLRRLGLDPEARGPCLRDPQPSSPQHPGATPPSGE
PGFPGSPQDLGGAQPSTARGAVLNNNKPQAHYEPPAAGTEVSASKRRCDWEEGLSSRRET
RAFSEGDQEKWSPESHHSKRNPGWDKRGLEKEDGSSKRRRLL
NT seq
8049 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacaccaggtggcatttccaccgttgacttcctgcagcgc
tatgcgtccaggacccactctggcgagtttcaaacagctgatgaagacctctgctactgc
ttagagtgtgtggccgaataccacagagcaagggacgatttaccattcctgcatgaggtt
ttatgggaattagaaaccttacgtctcataaatcattttgaaaaatccatgaaggcagaa
attggagacgatgatgaattgtatatagtagacaacaatggagaggcacagctgtttgac
tttactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccttatctgcttttacatgagcgtgttaatgaattatgcgttgaagcactttgtcggatg
gaacaagctaattgctcctttcaggtttttgacaagcatccgggcatctatttgtttctg
gtccatcccaacgaaatggttcggcgttgggctatcctgaccgcaagaaatttgggaaaa
gtggacagagatgattattatgacttgcaggaggttttgacttgcctttttaaagtcatt
gagttggggcttttggaaagtccagacatttatacttcttctatcctcgagaagggtaaa
ctgattcttctgccctcacacatgtatgataccaccaactacaaaaactattggttaggt
atatgcatgttgctgaccattctggaggagcaggccatggactcactgttgctgggctca
gacaaacagaatgatttcatgcagtcaatacttcacaccatggagaggcaatcagatgat
gatagtgtggatcctttctggccagcgttacactgtttcatggtgattctggatcgcctc
ggatccaaggtttggggtcagcgtatcgatcctattgaggcatttcagaccattatcaac
aatgtgagctacaataaggagatccagaatatacggaacagctccgtgaggaccaagtta
gaaccggagtcatattcgggtgatatggtgacttgcagccagattgtatacaattataat
cccgaaaagaccaaaaaggattcggggtggagatcagccatttgcccagattattgtcct
aacatgtatgaagagatggaaacattagccagtgtgcttcagtccgatattggtcaagac
atgcgtgttcataacagcacttttctgtggttcatcccttttgttcagtccctcatggac
cttaaggatttgggtgtggcgtatatagtggaggtcattcatcatctgcactccgaagtc
aaagatgtcctcaaccaaacagacgctgtgtgtgacaaagttactgaattttttcttcta
attttggtgtctgtgattgagctgcatagacataaaaaatgtctgcatctgctgtgggtt
agttcccagcaatgggtagaagccgttgtaaaatgtgccaagcttcctaccactgcattt
gcacggagttctgagaagtcatctggaaattgctccaaaggaacagcaatgatatcatct
ctgtcattgcattcaatgccatcgaattctgtacagctggcttgtgtccagctgattaga
agtctccttaaagaaggttatcagcttgggcagcaaactctatgtaagcgattctgggat
aagctcaacttatttctgcgtggaaatttatcgctaggttggcagttgactactcaggaa
acccatgaattacaaacttgtttaaagcaaattattaaaaacataaaagtcaaagtacct
caatataacacttttgtggatctgagtcctgcatgtaaaagctctcctgcatcttacagt
aaagaagaaaatgaacaaatagataggaagtctaataaagacctgccctgtctagaaagc
tccagcccaacatttcctaaagaaccaatgaaagcggagacctatcagatgcaagagaat
atattgatcaaagcaagtaacactatagaagaggataatgagcaaaattttataaaagac
tggaaactagaagatcatgtcccagccgagtcatgcataaagaagagtagtaaaaacctt
ttcactgaaaaaggtcaagatcaagttaaaagaagtacagggaagcagaagtctgtgaaa
gagaattgtacttcaaggaatgatccagaaaggggatgtgacagaggaataatcatgtca
acacgtttgttaaccagctctagcactgaatctctggagaaggcatccacatcaactgag
aatttctctttcaaggatgatgctcttggcaaaacctcaaaatcaaaaactaaggcacgt
aaagatgaaatctgtgctaagttatcacatgtaataaagaagcaacacaggaaaggtact
ttggtcagtaatactggcaatttagaggaaaacctggctgtgtctaacattgaccgtttc
tattcaaggaaagattcaggaggtcagaaaggggacggcttcatgcacaatctctcttta
gatcctaatggcattctggatgataaaaatggggaacaaaaatctcaaaacagtttactg
ctgaaaaagaagccactgaagagtgaagagttagatgttttctcttctcatgaaaacagc
tatcaaatgcaggaatgtcacattgatgataaagatttggtctcatttacggaagtgacc
aacacttttgtgaagaaaacttctcccttcaaagatcctgtgactgtttttgaatcaaga
gataaggaaagtagcaagaacagtagtccgttgtcttctcacttgagagaacaggctctt
ggcctaagtcctcagtctgacaccttaacagattctcaggtagacagagacctccacaag
ttatctttactagctcaggccagtgttattaagttcccatcagattcaactcaaaaaagc
tcatgccagctacaaagaagagtgaaggatgacagaaggtgtttcctggctgaccagaat
aatactggggaagcctgccggggccagattattattatttcagattctgatgatgatgac
gatgatgatgaaattctgggttttgagagacctattaagcaagataaaataggcatcaag
aatgaatgtccggagcagcatacttcaatagctagtgcgaatgtggaaaagaagctaata
aaggaagaggagacaaagtccctcttgcagtttgaggaatcggattctcagttttttgag
tttgaaagtccatgtgaagtgttttctgtttggcaagatcaggaaccagacaagaattca
gttcaagagaatgagaaaaattctttttcagctgacatagctgatatcacaaatgattgg
ggttatgagacagattatgtatctgaagaggttattaagaaagtagcagaaggcattgaa
aaacacacagaaccgcagagcagtatttctgttggggaaattcgtgaaattgaagtaaaa
aaacgtaagcgaaaacgatttgaaaaacctatggctgaagatcgtccaagaccttcacct
tctgatagaaatgaggaccagcctgatattcttaatgagaggagtctgactaaaaatgat
tttaaaagtatggacctaaggacaagtcccagttcaagtgttcagagagacaaagacact
acggttgcactaaagaagtcttctccaaaacttcgtacttattccagacccattaggaga
gtcccactttctaaaactcctaagaaagcgcattcagataccaagaaagggcagaataaa
agttcaaattacataagttgtaggacaactcctgctatagttccaccaaagaaattgcgc
cagtgccctgaaccaacttcaaaggttgagaaacttggtctaaagaaggctcctcgtagg
gcatttgagttgtctcagcgatctctagattatttagttaagttacgccgccatggcaca
agtgttggagtggttgatactagaaaaaagactaagttaatttcccctcagactctctct
gtcaaaaataataagaaactgctgacaagtcaagatcttcagttgcgaaggcagatgaga
tccaaatcacaaaaaaatagacaaggactttcggattatgaaagtaaagatactacaaga
gcagggccgtgtgcagcacagaattctgacatacttgtcccagaatcagatggttcagat
tacagttataaaggaggaactgaggcggttgctaacaccactgggaaacaatcaataaaa
cgtgtgtcttcagaaccagaacccatgaaaacaaaatatgtctctcaagtgacagatgat
acttgcctcttgagcccctgtgcttctgttgtgttaaatggaagaataccaacaaatgaa
ataaatgtctctgcttcagccgaccccttaggtggaagtgacccaacagtacatcgttta
gagttggcaactttgaaagacggagagctggactcgaacagtgatacagaagatgagaat
atatttctgacacagcacaatcctgaagatatggatttgtgttcacagatggagaacgga
aatgagaaactcattgaagtaattcgtggcaaagatacagcacaggtggaagaagattct
ctaagtcggcatcagttggaatcttggagtagcacaaaatgtaagtacaaagattgtgtt
gaaacaccgaaaaaccagggtgaatactgcgcaaaacactgtgaagccaaagcggccgat
gaagatgtatttcgtaaacctggtttgcctctttctgcatctaagccttcgagaccttcc
actgctaagatttttagctcaagtagtacttcacgaattgctaatctttccaagtctttg
gaaagtacccctgcacttccaccagctctaaaaaataagtcaagtgggacacaggctgtt
ttgaaagtcccacagccagcctctgtgttgtctccaaagccggtgggtgaagtgaagagt
ttgtgcaatattctccatcctcagactccaaataattccaacaggcaaggttacaaacta
acgtttggtgaaagcaaatccttctcagcttccactccagtcaacattctcttgtcatca
cagtccatctctgacacctttgtcaaagaggttttaaaatggaaatatgaaatgtttgtg
aactttgatcagtgcgggcccccagcaagcctttgtcagtccatctcaagacctgtgcct
atcagatttcaagattgtggcgattattttaatgtttttttccctttgatgatactgaat
acttttgaaacagtggcacaggagtggatcagctctccaaacaaagagaaattctatcag
ctgcacttacgaaaatttcctgctgattataaaaaatactgggagtttgtggttcatctt
gaggaatgcgaactcgcaaaacaacttcatccaaaggaaaatgatttggtgtttttgatt
cccgaacgacaaaacggagagaataaagatacagagagagatcacatggaagatctccgt
gattaccactgcgcgtatgttcataagtttcgccgcacttccgtcatgcgcaacgggaaa
tctgagtgttccctttccatccagattcaagataatttgccagtcaatttaaatgagctt
gtgaaatgcattgtaatcagttctctggtaactacacaaaggaagttgaaagccatgtct
ttgttgagtggacggaaccaactggccagagctgttctgaatccaaaccctatggacttc
tgtacgaaagatttactaactacaacgtctgagagaattatcacctacttaagagatttc
aacgaagaccagaagaaagcgatagaaactgcatatgccatggtcaagcactctccgtct
gttgccaagatctgtctgatacatggaccacctggaacaggaaaatcaaaaactattgtt
ggcctcctgtaccgcctcctgacagagaaccagaggaaggggcattcagatgaaaactcc
aatgccaaaatcaaacaaaaccgtgtccttgtgtgtgcgccttccaacgcggctgttgat
gaacttatgaaaaaaatcatcctcgaatttaaagaaaaatgtaaagacaagaagaatcct
ttgggaaactgtggagatataaatttagtacgtctcggtccagaaaagtctattaataat
gaggtcctaaaattcagtttggatagccaagttaaccacagaatgaaaaaagacttacct
tctcatgttcaggaaatgcatagaagaaaggaatttctagatcgtcaactagatgagctt
tcccgccagcgtgctttatgccgaggtggaagggaaatgcagaggcaagaattagatgaa
gaaattgcaaaagtttcaaaagagaggcaagaactagcttctaaaattaaagaggttcaa
gggcgcccacaaaaaacacagagcatcatcatcttggagtcccatgtcatctgctgcaca
ctgagcacgagtggtggcttactgctcgagtctgcttttcgtgggcaagggggtgtcccc
ttcagctgtgtcattgtggatgaggccgggcagtcttgtgaggttgagactctcactcca
ctcatccatcgttgtaacaagctcatcctcgtgggagatccgaaacagctccctcccacg
gtcatttctatgaaagctcaggagtatggctatgaccagtcaatgatggcgcgcttctac
aagctgctggaagacagcgtggagcacagcgtggtcggccggctgccagtcctgcagctc
accgttcagtaccggatgcacccggacatctgtctcttcccctccggctacgtttacaac
aaaagcttgaagacgagtagacaaactgaaaccagtcggtgttcatcagactggccattt
caaccttacctggtgttcgatgttggagacggttcagaaagacgggataatgactcatat
gtaaatgttcaagaaataaaactggtaatggaaataattaaacttattaaagacaaaaga
agggatgttactttccggaacattggcataataacccattacaaggctcagaagatgatg
attcagaaggatttggacaaagaatttgatagaaaagggccggcagaagtcgataccgtg
gacgggttccagggccggcagaaggactgcgtcattgtcacgtgcgtcagggcgaacacc
gcgcagggctcaatcgggtttctggcgagtttgcagagactgaacgtcaccatcacacga
gccaagtacagcctcttcatcctcggacacttaaggaccctcatggagaaccagcactgg
aaccacctgatccaggacgcccagaagcggggcgccatcatcaagacgtgtgacaggaac
tacaggcacgacgccgccaagatcctgaagctgaagccggtgctgcagagaagcgtgacg
cacccccccgctgtcgtcccggaggcgtccagacccccgggcggcttgcccagcagcagg
ctggacagcgagctcgccaagacgtccttcacgtccctctaccacacgccctcggactcc
aaggagtctgctggtaccgtcacggcaaaggaccctgaaaggccccttattcaggaccgg
cttcgggacccacgactgcttaggaggctgggcctggaccctgaagccagagggccgtgc
ctcagggatccgcagccctcgagcccccagcatcccggggcgacaccgccctcgggggag
ccgggcttccccgggagtccccaggatctgggaggcgcacagccgtccactgccaggggg
gccgttctgaacaacaacaaacctcaggcgcactatgaacctccagctgctgggaccgag
gtctctgcaagtaaaagaagatgtgactgggaagaagggctcagctccaggagagagacg
cgggctttcagtgagggggaccaggagaagtggagcccggagagccaccactcgaagagg
aaccctggctgggacaagaggggactggagaaggaggatggcagctcaaagagaagaagg
cttttatag
DBGET
integrated database retrieval system
