Enhydra lutris kenyoni (northern sea otter): 111150409
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Entry
111150409 CDS
T05871
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk00010
Glycolysis / Gluconeogenesis
elk00020
Citrate cycle (TCA cycle)
elk00620
Pyruvate metabolism
elk00785
Lipoic acid metabolism
elk01100
Metabolic pathways
elk01200
Carbon metabolism
elk01210
2-Oxocarboxylic acid metabolism
elk04066
HIF-1 signaling pathway
elk04922
Glucagon signaling pathway
elk05230
Central carbon metabolism in cancer
elk05415
Diabetic cardiomyopathy
Module
elk_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
111150409
00020 Citrate cycle (TCA cycle)
111150409
00620 Pyruvate metabolism
111150409
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
111150409
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
111150409
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
111150409
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
111150409
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
111150409
Enzymes [BR:
elk01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
111150409
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
MIF4G_like
Motif
Other DBs
NCBI-GeneID:
111150409
NCBI-ProteinID:
XP_022363534
UniProt:
A0A2Y9JVK6
LinkDB
All DBs
Position
Unknown
AA seq
431 aa
AA seq
DB search
MRKMLAAVSRVLGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDG
LKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAH
GFTFTRGLSVREILTELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALAC
KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCVFICENNRYGMGTSVERAAASTD
YYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSY
RTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKVGSTSVSAPRKLPFLGELPRSVGKD
GLWCQQDMKQSYLLNLETQQHSSVFLKIDSRYPSVFPVGLQNIPVIIAIINTSSKIATVS
TSRPRRVLVPY
NT seq
1296 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgctgtctctcgcgtgttgggcgtcgcccagaagccggcaagc
agagtgctcgtggcctcccgtaattttgcaaatgatgctacatttgaaattaagaaatgc
gatcttcaccggctggaggagggccctcctgtcaccacagtgctcaccagggaggacggg
ctcaagtactacaggatgatgcagacggtccgccggatggagttaaaggcagatcagctg
tacaagcagaagattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgttgt
gtgggcctggaggccggcataaatcctacagaccatctcatcacagcctatcgggctcat
ggctttaccttcactcgtgggctttctgtccgagaaattctcacagagcttacaggacga
agaggaggctgtgctaaagggaaaggaggatcgatgcacatgtacgccaagaacttctac
ggaggcaacggcatcgtcggagctcaggtgcccttgggagcggggattgctctggcctgt
aagtataacggaaaggatgaggtctgtctgactttatatggtgacggtgctgctaatcag
ggtcagatatttgaagcttacaacatggcagctttgtggaaactaccatgtgttttcatc
tgtgagaataaccgctatggaatgggaacatctgttgagagagcagcggccagcacagac
tactacaagagaggcgacttcatccctgggctgagggtagatggaatggacatcttgtgt
gtccgggaggcaacaaggtttgcagctgcctactgtagatctggaaaggggcccatactg
atggagctacagacctaccgttaccacggacacagcatgagcgaccctggcgtcagttac
cgtacccgagaagagattcaggaagtaagaagtaagagtgaccctatcatgctgctcaag
gatagaatggtgaacagcaatctggccagcgttgaagaattaaaggtaggctcaaccagt
gtttctgcacccagaaagctgccgttcctgggggagctgcctcggtcagtgggaaaggat
ggattgtggtgtcagcaggatatgaagcagtcctatttgcttaaccttgagacccagcag
cacagttctgtgttcctaaaaatagactccaggtatccatcagtgttcccagtggggctc
caaaatattcctgtgatcattgccattataaacacgtcttcaaaaatagcaactgttagt
acttccaggcctagaagggttctggttccctactag
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