| Entry |
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| Name |
(RefSeq) canalicular multispecific organic anion transporter 2
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| KO |
| K05667 | ATP-binding cassette, subfamily C (CFTR/MRP), member 3 |
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| Organism |
elk Enhydra lutris kenyoni (northern sea otter)
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| Pathway |
| elk04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:elk00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
111151538
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
111151538
04981 Folate transport and metabolism
111151538
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
111151538
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:elk02000]
111151538
Transporters [BR:elk02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
111151538
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1524 aa
MDALCGSKFWDSNLSVHTDSPDLTPCFQNSLLAWAPCFYLWAALPGYLLYREYHCEGYIV
LSRLSRLKTVLGVLLWCVSWADLFYSFHGLVHGRAPAPIFFVTPLVVGITMLLATLLIQY
DRLRGVQSSGILIIFWFLCVVCAIVPFRSRILLAMAKGKISDPFRFTTFYIYFALVLFAL
ILSCFREKPPFFSPRNVNPNPCPELSAGFLSRLCFWWFTKMAILGYRRPLEQQDLWSLKE
EDCSQNVVHGLLEAWKKLQKTSARHKTAASSGKRVSGEDEMLLGGRRRPQQPSFLWALLV
TFRSSLLISTCLKVAQDLLSFVNPQLLSILISFISNPMAPTWWGFLVAGLMFACSMMQTL
ILEQFYHFVFTKALKLRLAIIGVIYRKALLISNSAKRESPVGEIVNLMSTDAQRFMDLAP
FLNLVVSVPLQIILAMYFLWQNLGPSILAGVALMVLLIPLNGAVAMKMRAFQAEQMKFKD
SRIKLMSEILAGIKVLKLYAWEPSFLEKVEGIREDELRLLCKSAYLQAISTFTWVCTPVL
VTLTTLGVYVSVDPNNVLDAEKAFVSVSLFNILKIPLNMLPQLISNLIQTSVSLKRIQHF
LSQDELDPQCVERKTITPGYAVTIHNGTFTWAQDLPPTLHSLDIQVPKGALVAVVGPVGC
GKSSLVSALLGEMEKLEGTVCVKGSVAYVPQQAWIQNCTLQENVLFGRALDPKKYHQALE
ACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSEADLFLLDDPLSAVDSHV
AKHIFDQVIGPEGVLAGKTRVLVTHSISFLPQMDIIIVLADGQVSEVGSYPDLLGRNGSF
ANFLCNYAPEEDKESLKKNSRTALENTEDEELLLIEDTLSNHTDLTDNEPVLYEVQKQFV
RQLSVMSSEGEGQGWPVPRRRLCSAGKAVQAAEAKAMGALIQEEKAAMGTVKLSVFWDYA
KAMGLYTTVAICVLYLCQTAAAIGASVWLSAWTNEAMVDSRQNNTSMRLGVYAALGVLQG
ILVILAAVTLTVGSVHAARSLHQALLHNKMRSPQSFFDTTPSGRILNRFSKDIYVIDEVL
APTILMLLNSFYNSLATLVVIVASTPLFTVVTLPLGVFYILMQRFYVATSLQLKRLESIS
RSPIYSHFSETVTGSSVIRAYGRSQDFQAISDAKVDANQRSCYAHIASNRWLGVQVEFVG
NCVVFFAALFAVIGRNSLSPGLVGLSVSYALQITLTLNWMIRMMSDLEANIVAVERVKEY
SKTETEAPWLVEGSRPPAGWPPKGEVEFRNYSVRYRPGLELVLKNLSVRVRGGEKVGIVG
RTGAGKSSMTLCLFRILEAAEGEILIDGLNVADIGLHDLRSQLTIIPQDPILFSASLRTN
LDPFGHYSEEDIWRALELSHLHTFVSSQPAGLEFQCSEGGENLSVGQRQLVCLARALLRK
SRILVLDEATAAIDLETDDFIQAIIRTQFESCTVLTIAHRLNTIMDYTRVLVLDKGTIAE
FDSPANLIAARGIFYGMARDAGLA |
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| NT seq |
4575 nt +upstreamnt +downstreamnt
atggacgccctgtgcggctccaagttctgggactccaatctgtccgtgcacactgacagc
ccggacctcactccctgcttccagaactctctgctggcctgggcgccctgcttctacctg
tgggccgccctgcccggctacctgctctatcgggaataccactgcgaaggctacatcgtc
ctctcccgcctctccaggctcaagacggtcttgggtgtcctgctgtggtgtgtctcctgg
gctgacctcttctactccttccatggcctggttcacggcagggcccccgccccaatcttc
tttgtcacccccttggtggtggggatcaccatgctgctggccaccctgctaatccagtat
gaccggctgcggggggtacagtcctcggggatcctcatcatcttctggtttctgtgtgtg
gtctgtgccatcgtccccttccgctccaggatcttgttggccatggcaaagggaaagatc
tcggaccccttccgcttcaccactttctacatctacttcgccctggtgctctttgctctc
atcctgtcctgcttcagggagaagccgccatttttctccccaaggaatgtcaaccctaat
ccctgcccggaactcagtgctggcttcctctcccgcctgtgtttctggtggttcacaaag
atggccatccttggctaccggcgcccactggagcagcaggacctctggtccctgaaggag
gaggactgttcacagaacgtggtgcacgggctgctggaggcctggaagaagcttcagaag
acctctgcgcgacacaagactgcggcgtcatccgggaagagagtgtccggtgaggacgag
atgctgctggggggccggcgcaggccccagcagccctccttcctgtgggccctgctggtc
accttccgttccagcctcctcatcagcacatgcctcaaggtggcccaggacctgctctcc
ttcgtcaatccacagctgctcagcatcctgatcagttttatctccaaccccatggccccc
acctggtggggcttcctggtggccgggctgatgtttgcgtgctccatgatgcagaccctg
attttagagcagttttatcacttcgtcttcacgaaggcgctgaaacttcgtttggcgatc
attggtgtcatctataggaaggctctgcttatcagcaattcagccaaacgggagtcccca
gtgggagaaattgtcaacctcatgtctacagatgcccagcgcttcatggatctcgctccc
ttcctcaacctggtggtgtccgtacccctgcagatcattctggcaatgtacttcctctgg
cagaacctgggtccctccatcctggctggggtcgctctcatggtcttgctgatcccgctc
aacggagccgtggccatgaagatgcgtgctttccaggcagagcaaatgaagttcaaggac
tcacgtatcaagctgatgagtgagatcctggctggcatcaaggtgctaaagctgtatgcc
tgggagccgagtttcttggagaaggtagaaggcatccgggaggacgagctccggctgctg
tgcaagtccgcctacctccaagccatctccaccttcacctgggtctgcacccctgtcctg
gtgaccctgaccacgcttggggtgtatgtgtctgtggacccaaacaatgtgctggacgct
gagaaggcctttgtgtctgtgtccctgttcaatattttaaagattcccctcaacatgttg
cctcagttaatcagcaacctgatccagaccagtgtgtctctgaaacggatccagcatttc
ctgagccaagatgaacttgacccccagtgtgtggaaagaaagaccatcaccccaggatat
gctgtcaccatacacaatggcaccttcacctgggcccaggacctgccccctacactgcac
agcctagacatccaggtgccaaaaggggcactggtggccgtggtggggcccgtgggctgt
gggaagtcttccctggtttctgccctgctgggagagatggagaaactggaaggcacggtg
tgtgtgaagggctccgtggcctacgtgccccagcaggcatggatccagaattgcacgctt
caggaaaacgtactgttcggccgagccctggaccccaagaagtaccatcaggctctggaa
gcctgtgccttgctagctgacctggagatgctgcctggcggggaccagacagagatcgga
gaaaagggcattaacctgtctgggggccagcgacagcgggtcagtctggcccgagctgtt
tacagtgaagctgatctttttttgctggatgacccactgtcagccgtggactctcatgtg
gccaagcatatctttgaccaagtcatcgggccagaaggtgttctggcaggcaagacacgg
gtgctggtgacacacagcatcagcttcctgccccagatggacatcatcatagtgctggct
gatgggcaggtgtccgaggtgggctcctatccagacctgctgggacgcaatggctccttt
gccaactttctctgcaactacgcgcccgaggaggacaaggagagcctgaagaagaacagc
aggaccgccttggagaacacagaggatgaggagctgctgctgattgaagacacgctgagc
aatcacacagacctgacagacaacgagccggtcctctatgaggtccagaagcagtttgtg
agacagctgagtgtcatgtcctcggaaggcgagggccagggctggcctgtgccccggaga
cgcctgtgttcagcagggaaggcagtgcaggcagcagaggcgaaggcgatgggggcgctg
atccaggaggagaaggcggcaatgggcactgtgaagctgagtgtgttctgggattatgcc
aaggccatggggctctataccacagtggctatctgtgtcctatacctgtgtcaaactgcg
gctgccattggggccagcgtatggctcagtgcctggaccaatgaggctatggtggacagc
cgacagaataacacctccatgaggctgggtgtctatgctgccttgggagttctgcaagga
atcctggtgattctggcagccgtcacgctgacggtgggcagcgtccacgcggcacgctca
cttcaccaagcgctgctgcacaacaagatgcgctcgccacagtccttcttcgacacgacg
ccctccggccgtatcctcaatcgcttctccaaagatatctacgtcatcgatgaggttctg
gcccccactatcctcatgctgctgaattccttctacaactccctcgccaccctcgtggtc
atcgtggccagcacgccgctcttcaccgtggtcaccctgcccctgggggtcttctatatc
ttgatgcagcgcttctatgtggcgacgtcgctgcagctaaagaggctggagtccatcagc
cgctcgcccatttactcccacttttcggagacagtgaccggctccagcgtcatccgggcc
tatggccgcagccaagacttccaggctatcagtgacgctaaggtggacgccaaccagagg
agctgctatgcccacattgcctccaacaggtggctgggagtccaagtggagttcgtaggc
aactgtgttgtgttctttgctgcactctttgctgtgatcggcagaaacagcctgagtccg
gggctggtgggcctatccgtgtcctatgccctacagataacattgactctgaattggatg
atccgaatgatgtccgacttggaagctaacattgtggctgtagagagagtcaaggagtac
tccaagacggagactgaggccccctggttggtggagggcagccgtcctcctgcaggctgg
cccccgaagggcgaggtggagttccgcaattactccgtgcgctaccggcctggcctggag
ctggtgctgaagaacctgagtgtgcgcgtgcgcggcggcgagaaggtggggatcgtgggc
cgcacgggggccggcaaatcatccatgaccttgtgcctgttccgcatcttggaggcggca
gagggtgaaatcctcatcgacggcctcaacgtggcagacatcggcctccacgacctccgc
tctcagctgaccatcattccccaggaccccattctgttctccgcatccctgcgtacgaac
ctggacccctttgggcattactccgaggaagatatatggcgagccttggagctgtcccac
ctgcacaccttcgtgagctcacagccagcaggcctggaattccagtgctccgagggaggg
gagaatctcagcgtgggccagcgccagcttgtgtgcctggcccgagccctgctccgcaag
agccgaatcctggttttagacgaggccacagcagccatcgacctggagacggacgacttc
atccaggccatcatccgcacccagtttgagagctgcacggtgctgaccatcgcccaccgg
ctcaacaccatcatggactacaccagggtcctggtcctggacaaagggacgatagcagaa
tttgactctccggccaacctcattgcagccagaggcatcttctatgggatggccagagac
gctggacttgcttag |
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