Enhydra lutris kenyoni (northern sea otter): 111154402
Help
Entry
111154402 CDS
T05871
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk00220
Arginine biosynthesis
elk00330
Arginine and proline metabolism
elk01100
Metabolic pathways
elk04020
Calcium signaling pathway
elk04022
cGMP-PKG signaling pathway
elk04066
HIF-1 signaling pathway
elk04071
Sphingolipid signaling pathway
elk04151
PI3K-Akt signaling pathway
elk04370
VEGF signaling pathway
elk04371
Apelin signaling pathway
elk04611
Platelet activation
elk04915
Estrogen signaling pathway
elk04921
Oxytocin signaling pathway
elk04926
Relaxin signaling pathway
elk04931
Insulin resistance
elk04933
AGE-RAGE signaling pathway in diabetic complications
elk05415
Diabetic cardiomyopathy
elk05417
Lipid and atherosclerosis
elk05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
111154402
00330 Arginine and proline metabolism
111154402
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
111154402
04371 Apelin signaling pathway
111154402
04066 HIF-1 signaling pathway
111154402
04020 Calcium signaling pathway
111154402
04071 Sphingolipid signaling pathway
111154402
04022 cGMP-PKG signaling pathway
111154402
04151 PI3K-Akt signaling pathway
111154402
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
111154402
09152 Endocrine system
04915 Estrogen signaling pathway
111154402
04921 Oxytocin signaling pathway
111154402
04926 Relaxin signaling pathway
111154402
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
111154402
05418 Fluid shear stress and atherosclerosis
111154402
05415 Diabetic cardiomyopathy
111154402
09167 Endocrine and metabolic disease
04931 Insulin resistance
111154402
04933 AGE-RAGE signaling pathway in diabetic complications
111154402
Enzymes [BR:
elk01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
111154402
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
111154402
NCBI-ProteinID:
XP_022369666
UniProt:
A0A2Y9K8A1
LinkDB
All DBs
Position
Unknown
AA seq
1211 aa
AA seq
DB search
MGNLKSVGREPGPPCGLGLGLGLGLCGKQGPASPTSSEPSRAPAPAPPPAPDHSSPPLTR
PPDGPKFPRVKNWEVGSITYDTLSAQSQQDGPCTPRRCLGSLVFPRKLQSRPSQDPQPAE
QLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNA
PRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGDF
RIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPE
LFALPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTE
IGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVDHH
AATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPAFRYQPDPWK
GSGSKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRL
FRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSP
RPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFC
AFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKAAAR
DIFSPKRSWKRQRYRLSTQAEGLQLLPGLIHVHRRKMFQATVLSVENLQSSKSTRATILV
RLDTGGQEALQYQPGDHIGICPPNRPGLVEALLSRVEDPPPPGEPVAVEQLEKGSPDLPC
TSHPSGGPPPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEESSEQQELES
LSQDPRQYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSAHPGE
IHLTVAVLAYRTQDGLGPLHYGVCSTWLSQLKAGDPVPCFIRGAPSFRLPPDPTLPCILV
GPGTGIAPFRGFWQERLHDIDSKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQERGVFGR
VLTAFSREPDSPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILA
TEGDMELDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHLRGAVPWA
FDPPGPDTPSP
NT seq
3636 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagtgtgggccgggagcccgggcccccatgtggcctggggctgggc
ctgggcctggggctgtgtggcaagcagggcccggcctcccccacctcctctgagcccagc
agggcgcccgcacccgcgcccccacccgcaccagaccacagcagccccccactcacccgg
cccccggacgggcccaagttccctcgagtgaagaactgggaggtggggagcatcacctac
gataccctgagtgcccagtcacagcaggatgggccctgcaccccccgacgctgcctgggc
tcgctggtgttcccgaggaaactgcagagccggccatctcaggacccccaaccagctgag
cagctgctgagtcaggccagggacttcattaaccagtactacagctccatcaagaggagc
ggctcccaggcccatgagcagaggcttcaggaggtggaagccgaggtggcagccacgggc
acctaccagctccgggagagtgagctggtgttcggggccaagcaggcctggcgtaacgca
ccccgctgcgtgggccggatccagtgggggaagctgcaggtgttcgatgcccgggattgc
agctcagcccaggagatgttcacctacatctgcaaccacatcaagtatgccaccaaccgg
ggcaacctccgctcagccatcacagtgttcccccagcgcgccccaggccgtggagacttc
cgaatctggaacagccagctggtgcgctacgcggggtacaggcagcaggatggctcagtg
cgcggggaccccgccaacgtggagatcaccgagctctgcatccagcatggctggacccca
ggaaacggccgctttgacgtgctgccactcctgctccaggccccagatgaacccccagag
ctctttgctctgccccccgagctggtcctcgaggtgcccctggagcaccccacgctggag
tggtttgcggccctgggcctgcgctggtatgccctcccggcggtgagcaacatgctgctg
gaaattgggggcctggagttccccgcggcccctttcagcggctggtacatgagcactgag
attggcacgcggaacctgtgtgaccctcaccgatataacatcctggaggatgtggcagtc
tgcatggacttggacaccaggacaacctcatccctgtggaaagacaaggcagcggtggaa
atcaacttggccgtgctgcacagttaccagctggccaaagtgaccatcgtggaccaccac
gctgccaccgcctccttcatgaagcacctggagaacgagcagaaggctagggggggctgc
cctgccgattgggcctggatcgtgccccccatctctggcagcctcacccctgtcttccat
caggagatggtcaactacgtcctgtcccccgccttccgctatcagccagacccatggaag
gggagtggatccaagggtaccggcatcaccaggaagaagacctttaaggaagtggccaat
gcggtgaagatctcagcctcgctcatgggcaccgtgatggcaaagcgagtgaaggcgacc
atcctgtatggctccgagaccggccgggcccagagctacgcacagcaactggggagactc
ttccggaaggctttcgacccccgggtcctgtgcatggatgagtacgatgtggtgtccctt
gagcatgagacgctggtgttggtggtgaccagtacatttgggaatggtgaccccccagag
aatggagagagttttgcagcggccctgatggagatgtccggcccctacaacagctctcct
cggccagaacagcacaagagttacaaaatccgcttcaacagcgtctcctgctcagacccg
ttggtgtcctcttggaggcgaaagagaaaggagtccagtaacacagacagcgcaggggcc
ctggggaccctcaggttctgtgtgttcgggctgggctcccgggcatacccccacttctgc
gcctttgctcgtgcggtggacacacggctggaagagctgggcggggagcggctactgcag
ctgggccagggagatgagctgtgtggccaggaggaggccttccgtggctgggcccaggcc
gcattccaggcctcctgtgagactttctgcgtgggagaggatgccaaggccgctgcccgg
gacatattcagccccaaacggagctggaagcgccagcgataccggctgagcacccaggcc
gagggcctccagttgctgccaggcctgatccacgtgcacaggagaaagatgttccaggct
acggtcctctcagtggaaaacctgcaaagcagcaagtccacccgggccaccatcctagtg
cgcctagacactggaggccaggaggccctacagtaccagcccggggatcacataggcatc
tgcccgcccaaccggcccggcctcgtggaggcgctgctgagccgcgtcgaggatccgcct
ccaccgggcgagcccgtggctgtggagcagctggagaagggtagcccggacctcccctgt
acatcacacccctcaggtggcccgccccctggctgggttcgggacccccggctgccccca
tgcacgctgcgccaggctctcaccttcttcctggacatcacttccccgcccagtcctcaa
ctccttcgactgctcagcaccctggccgaagagtccagcgaacagcaggagctcgagagc
ctcagccaggacccgcggcagtacgaggagtggaagtggttccgctgccccacgctgctg
gaggtgctggagcagttcccatctgtggccctgcccgcaccgctgctcctcacccagctg
cccctgctccagccccggtactactcagtcagctcggcacccagcgcccacccaggagag
atccacctcacagtagctgtgctagcatacaggacacaggacggactgggcccccttcat
tatggagtctgctccacgtggctgagccagctgaaggccggggatcctgtaccctgcttc
atcaggggggctccctccttccggctgccgcctgaccccaccttgccctgcatcctagtg
ggccctggcacaggtattgcccccttcaggggattttggcaggagcggctgcatgacatt
gacagcaaaggcctgcagcccgcccccatgactttggtgttcggctgccgatgctcccag
ctcgaccacctttaccgcgacgaggtgcaggatgcccaggagcgcggagttttcgggcgc
gtcctcaccgccttctcccgggagcccgacagccctaagacctacgtgcaggacatcctg
cggacggagctggctgctgaggtgcaccgcgtgctgtgcctcgagcggggccacatgttt
gtgtgcggcgacgtcaccatggcaaccagcgttctgcagacggtgcagcgtatcctagcg
acggagggcgacatggagctcgacgaggccggcgacgtcatcggcgtgctgcgggatcag
caacgctatcacgaggacattttcgggctcacactgcgcacccaggaggtgacaagccgc
atacgcacccagagcttttccttgcaggagcgacatctgcggggcgcagtgccctgggcg
ttcgacccgcccgggccagacacccccagcccctga
DBGET
integrated database retrieval system
