Enhydra lutris kenyoni (northern sea otter): 111155166
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Entry
111155166 CDS
T05871
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
111155166
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
elk03032
]
111155166
03036 Chromosome and associated proteins [BR:
elk03036
]
111155166
Enzymes [BR:
elk01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
111155166
DNA replication proteins [BR:
elk03032
]
Eukaryotic type
DNA Topoisomerases
111155166
Chromosome and associated proteins [BR:
elk03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
111155166
Centrosome formation proteins
Centriole proteins
111155166
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
111155166
NCBI-ProteinID:
XP_022370951
UniProt:
A0A2Y9KBV5
LinkDB
All DBs
Position
Unknown
AA seq
1621 aa
AA seq
DB search
MAKAGGGGGAGAGGNGALTWVTLFDQNNASKKEESETANKNDSSKKLSVERVYQKKTQLE
HILLRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKN
MTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGG
RNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQP
DLSKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDE
TGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVV
KKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKA
ASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTE
GDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKS
YDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKAS
KNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYA
GPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINK
ELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGE
QALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLSRLLFPAV
DDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLD
GLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLE
PMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMV
LFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQG
KITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGPD
FNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQ
EREDILAGMAGKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASKKLLKKKK
GDLDTTAVKVEFDEEFSGTPVEGTGEEALISSAPVNKGPKPKREKKEPGTRVRKTPTSSG
KSSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDA
DDDDDNNDLEELKVKASPVTNDGEDEFIPSDGLDKDEYTFSPGKSKATPEKSSHDKKSQD
FGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDT
TAKPKRAPKQKKVEPINSDSDSEFGIPKKTTPLKGKGRGAKKRKASGSENEGDYNPGRKT
SKTTSKKLKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFAESDEEEDVDFAMF
N
NT seq
4866 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggcgggcggcggcggcggcgcgggagccggcggcaacggggcactgacctgg
gtgactctttttgatcagaacaatgcctcaaaaaaggaagagtcagaaaccgcaaacaaa
aatgattcttcaaagaagttgtctgttgagagagtgtatcagaaaaagacacaacttgaa
catattctccttcgtcctgatacgtatattgggtcagtggaaccattgacacagctaatg
tgggtatatgatgaagatgtcggaatgaattgcagagaggttacctttgtgccaggttta
tacaagatctttgatgaaattttggttaatgcagctgacaataaacagagggacaagaat
atgacttgtattaaagtttctattgatcctgaatcaaatattataagcatttggaataat
gggaaaggcattccagtagtagaacacaaagtagagaaagtttatgttcctgcattaatt
tttggacagcttttaacatccagtaactatgatgatgatgagaaaaaagtaacaggtggt
cgcaatggttatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaaact
gcttgcaaagaatacaaacacagttttaagcagacatggatgaataacatgatgaagact
tctgaagccaaaattaaacattttgatggtgaagattacacatgcataacattccaacca
gatctgtctaaatttaagatggaaaaacttgacaaggatattgtggcccttatgaccaga
agagcttatgatttggctggttcatgcaagggggtcaaggtcatgtttaatggaaagaaa
ttgcctgtaaatggatttcgcagttatgtagatctttatgtgaaagacaagttggatgaa
actggagtggccctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgtctc
acactgagtgaaaagggattccagcaaatcagctttgtaaatagtattgcaacaacaaaa
ggtggacgtcatgtggattacgtagtagatcaagttgttggtaaactgattgaagtagtt
aagaaaaagaacaaagccggtgtatcagtaaaaccatttcaagtaaaaaaccatatatgg
gtttttattaactgccttatcgaaaatccaacttttgattctcaaactaaggaaaacatg
acgctgcaacccaaaagttttgggtccaaatgccaactgtcagaaaaattttttaaagca
gcttctaactgtggcattgtagaaagtattctgaattgggtgaaatttaaggcccagact
cagctgaacaagaagtgttcatcagtaaagtatagtaaaatcaaaggtattcccaaactg
gatgatgctaatgatgctggtggcaaacattccctggagtgtacactgatactaaccgag
ggagactctgccaaatcattggctgtgtcgggattaggtgtgattgggcgagacagatat
ggagtctttccacttaggggaaaaattcttaacgtacgggaagcttctcataaacagatc
atggaaaatgcagaaataaacaatattatcaaaatagttggtctacaatacaagaaaagt
tatgatgatgcagaatctctgaaaactttacgctatgggaagattatgattatgactgat
caggatcaagatggttctcacataaaaggtctgcttattaatttcatccatcacaattgg
ccatcacttttgaagcatggttttcttgaagagttcattactcctattgtaaaggctagc
aaaaataaacaggaactttccttctatagtattcctgaatttgacgagtggaaaaaacat
atagaaaaccagaaagcctggaaaataaaatactacaaagggttgggtaccagtacagct
aaagaagcaaaggaatattttgctgatatggaaaggcaccgcatcttatttagatatgct
ggtcctgaagacgatgctgccattaccttggcattcagtaaaaagaagattgatgacaga
aaagaatggttaacaaattttatggaagaccggagacagcgtaggttacatggcttacca
gagcaatttttgtatggtacagcaacaaagcatttgacttacaatgatttcatcaacaag
gaattgattctcttctcaaattcagacaatgaaagatctataccatctcttgttgatggc
tttaaaccaggacaacgaaaagttttatttacctgtttcaagaggaatgataaacgtgaa
gtaaaagttgcccagttggctggatctgttgctgagatgtctgcttatcatcatggagaa
caagcattgatgatgactattgtgaatttggctcagaactttgtgggaagcaacaacatt
aatttgcttcagcctattggtcagtttggaactcggcttcatggtggcaaagatgctgca
agccctcgttatattttcacaatgttaagctctttatcaagactgctttttcctgctgtg
gacgacaacctgcttaaattcctttatgatgataatcaacgcgttgagcctgagtggtat
attcctataattcccatggttttaataaatggtgctgagggcattggtactggatgggct
tgtaaactacccaactatgatgctagggaaattgtgaacaatgtcagacgaatgctagat
ggcttggatcctcatcctatgcttccaaactacaaaaactttaaaggaaccatccaagag
cttggtcaaaaccagtatgcagtcagtggtgaaatatttgtggtggatagaaacacagta
gagattacagaacttccagttagaacttggacacaggtatacaaagaacaggttttagaa
ccaatgctcaatggaacagataaaacaccagcattaatttctgattataaagaatatcat
actgatacaactgtgaaatttgtggtgaaaatgactgaagagaagcttgcacaagcagaa
gctgctggattgcacaaagtttttaaacttcaaactactcttacttgtaattccatggta
ctctttgatcatatgggatgtctcaagaagtatgaaaccgtgcaagacatcttgaaagaa
ttctttgatttacgattaagttactatggtttacgtaaggaatggcttgtaggaatgttg
ggagcagagtccacaaagcttaacaatcaagcccgtttcattttagagaagatacaagga
aaaattactatagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggt
tatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcggcagaagaggaa
gaaacacaaaaccagcatgatgatagttcctctgattcaggaactccttcaggccccgat
tttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaactg
attaaacagagagatgcaaaagggcgagaggtcaatgatcttaaaagaaaatctccttca
gatctttggaaagaagacttagcagcatttgttgaagaactggataaagtggaagcgcaa
gaacgggaggatattctggctggaatggcaggaaaagcaataaaaggtaaagttggcaaa
cctaaggtgaagaaacttcaattggaagagacaatgccctcaccttatgggagaagaata
gttcctgaaattactgctatgaaggcagatgccagcaaaaagttgctgaagaagaaaaag
ggtgatcttgataccacagcagtaaaagtagaatttgatgaagaatttagtggaacgccg
gtagagggtactggagaagaggcattgatctcgtcagctcctgtaaataaaggtcccaaa
cccaaaagggaaaaaaaggaacctggtaccagggtgagaaaaacacctacatcgtctggt
aaatccagtgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaagtca
gaaagtgacttggaagaaacagaacctgtggttattccaagagattctttgcttaggaga
gcagctgcggaaaggcccaagtacacatttgatttctcagaagaagaggatgatgatgct
gatgatgatgatgataataatgatttagaggaattgaaagtcaaagcatctcctgtaaca
aatgatggggaagatgaatttattccttcagatggcctagataaagatgaatatacattt
tcaccaggcaaatcaaaagctactccagaaaaatcttcacatgacaaaaaaagtcaagat
tttgggaatctcttctcatttccttcatattctcagaagtcagaagatgattcagctaaa
tttgacagtaatgaagaagattctgcctctgtattttcaccatcatttggtctgaaacaa
acagataaggttccaagtaaaactgtagctgctaaaaagggaaaaccatcttcagataca
actgctaagcccaagagagcccctaaacagaagaaagtagagcctatcaactctgattca
gattcagaatttggcattccaaagaagactacacccctaaaaggtaaaggccgaggggca
aagaaaaggaaagcatctggctctgaaaatgaaggtgattataaccctggcaggaaaaca
tccaaaacaacaagcaagaaactgaagaaaacctcttttgatcaggattcagatgtggac
atcttcccatcagacttcacttctgaaccaccttctctgccacggactggtagggctagg
aaagaagtaaaatattttgcagagtctgatgaagaagaagatgttgattttgcaatgttt
aattaa
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