Enhydra lutris kenyoni (northern sea otter): 111155699
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Entry
111155699 CDS
T05871
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
elk
Enhydra lutris kenyoni (northern sea otter)
Pathway
elk00230
Purine metabolism
elk00670
One carbon pool by folate
elk01100
Metabolic pathways
elk01523
Antifolate resistance
Module
elk_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
elk00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
111155699
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
111155699
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
111155699
Enzymes [BR:
elk01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
111155699
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
111155699
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
111155699
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
ATP-grasp_3
ATP-grasp_4
Dala_Dala_lig_C
RimK
Sacchrp_dh_NADP
ATP-grasp_5
Motif
Other DBs
NCBI-GeneID:
111155699
NCBI-ProteinID:
XP_022371717
UniProt:
A0A2Y9KD61
LinkDB
All DBs
Position
Unknown
AA seq
1009 aa
AA seq
DB search
MAARVLVIGSGGREHALAWKLAQSNHVKHVLVAPGNAGTSSLEKISNTAISINDHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGNLTSAGVQCFGPTAEAAQLESSKRFAKEFMDRHGIP
TARWRAFTKPEEACSFIMSADFPALVVKASGLAAGKGVIVAKSKEEACRAVQEIMQDKAY
GAAGETIVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDHGPNTGGMGAYCPAP
QVSKDLFLKIKNTILQRTVDGMQQEGMPYTGVLYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSILDGLLCTYLPVWFENCTAVTVVMASKGYPGDYTKGVEITGFPAA
QALGLEVFHAGTALKDGRVVTNGGRVLTVTAIRENLILALEEAKKGLATIKFEGAIYRKD
IGYRAIAFLQQPRGLTYKESGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLNTTEAVVAGIARACGKAGCALLGGETAEMPDMYPPGEYDVAGFAVGAMERDQKLP
HLERITEGDVVVGVASSGLHSNGFSLVRKIVAKSSLQYSSPAPEGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDAQTWRVPRIFSWLQQEG
HLSEEEMARTFNCGIGAALVVSKDLAEQILRDIKQHKEEAWVIGKVVACPEGSPRVKVKN
LIETMQINGSVLENGTVKNNFSVQSKKARVAVLISGTGSNLQALIDSTREPSSCAHIVVV
ISNKAAVAGLDKAETAGIPTRVINHKLYKSRVEFDTAIDQVLEEYSTDIVCLAGFMRILS
GPFVRKWDGKMLNIHPSLLPSFKGSNAHEQALEAGVTVTGCTVHFVAEDVDAGQIILQEP
VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGAVRLGENGKICWVTE
NT seq
3030 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttgtaattggcagcggtggaagggaacacgcactggcctggaaa
cttgcacagtctaatcatgtcaaacatgtgttggttgccccaggaaatgcaggcacttcc
tccttggaaaagatttcaaatactgccatctcgatcaatgaccacacagcccttgctcag
ttctgcaaagatgagaaaattgaattcgtagttgttggaccagaggcacctctggctgct
ggaattgttgggaacctgacatctgcaggagtccaatgctttggtcccactgcagaagca
gctcagttagagtccagcaagagattcgccaaagagtttatggaccgacatggaatccca
actgcacggtggagagctttcaccaaacctgaagaagcctgcagctttataatgagtgca
gacttccctgctttggttgtgaaggccagtggtcttgcggctggaaaaggagtgattgtt
gccaagagcaaagaagaggcctgcagggctgtacaggagatcatgcaggataaagcttat
ggagcagctggagaaacaattgtcattgaagaacttctggaaggagaagaggtgtcttgt
ctgtgcttcactgatggaaggactgtggctcccatgcccccagcacaagaccataagcga
ttgctggagggagatcacggccccaacacaggggggatgggagcctattgtccagcacct
caggtttctaaggatttgttcctgaaaataaaaaataccattcttcagaggacagtggat
ggcatgcagcaagagggtatgccatacacaggtgttctctatgctggtataatgctgacc
aaggatggcccaaaagttctggagttcaattgccgtttcggtgatccagagtgccaagtg
atcctcccgcttcttaaaagtgatctttatgaagtgattcagtctatcttggatggcctg
ctctgtacatatctgcctgtttggtttgaaaactgcactgcagtaactgtcgtgatggca
agtaaaggctatccgggagattacaccaagggtgtggagataacagggtttcctgcggct
caagctttaggactggaggtgttccacgcaggcactgccctgaaagatggcagagtggtg
actaacgggggtagagtccttacggtcacagcgatccgggaaaatctcatcttggccctt
gaagaagccaaaaaaggactagctactataaagtttgagggagccatttacaggaaggac
ataggctatcgcgccatagcttttctccagcagcccaggggcctgacttacaaggaatct
ggggtagacattgcagctggaaatatgctggtcaagaaaattaaacctttagcaaaagct
acctccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctcttctggcaagtggaacagatggtgttggaactaaactg
aagattgcccagcagtgtaacaaacatgatacaattggtcaagatctggttgcaatgtgt
gtcaatgacattctggcccaaggggcagagccccttttcttcctcgattacttttcctgt
ggaaaacttgaccttaatacaactgaagctgttgtcgctggaatcgccagagcctgtgga
aaagctggatgtgctctccttggaggtgaaactgcagaaatgcctgacatgtatcctccg
ggagaatatgacgtagctggttttgctgttggtgccatggagcgggatcagaaactccct
cacctggaaagaatcactgaaggggatgttgttgttggagtagcttcatctggtcttcac
agcaatggatttagccttgtaaggaaaattgtagcaaaatcttccctccagtactcatct
ccagcacctgaaggctgtggtgatcagaccttaggggacttacttcttactccaaccaga
atctacagccattcactgctacctgtcctacgttcaggacacgtcaaggcctttgcccat
attaccggtggaggattgctagaaaacatccccagagtccttcctcagaagtttggggtg
gatttagatgcccagacctggagggtccccaggatcttctcatggttacagcaggaagga
cacctctctgaggaagaaatggccagaacatttaactgtgggattggggctgccctcgtg
gtgtcaaaggatctggcagagcagattctgagagatattaagcagcacaaggaagaagcc
tgggtgattggcaaggtggtggcatgtcctgaaggttctcctcgtgtgaaagtcaagaat
ttgatagaaaccatgcaaataaatggatcagtattagaaaatggcaccgtgaaaaataat
ttctctgtccaatcaaaaaaggcaagagtggctgtcttaatatctggaacaggatcaaac
ctgcaagctctcatagacagtactagggagccaagtagctgtgcgcacattgttgtcgtt
atctccaacaaagccgcagtggctggcttagataaagcggagacagctggaattcccacc
agagtaattaatcataaattatataaaagtcgggtagaatttgacactgcaattgaccaa
gtccttgaagagtactccacagacatagtctgtcttgcaggattcatgagaattttatct
ggcccctttgtcaggaaatgggatgggaagatgctcaacatccacccatccttgctcccg
tcttttaagggttcaaatgcccacgagcaagccctagaagccggcgtcacagtcaccggg
tgtactgtgcactttgtagctgaagatgtagatgctggacagattattttacaagaacct
gtgccagtgaagagaggtgacactgttgcaactctgtctgaaagagtgaaattagcagag
cacaaaatattccccgcagccctccagctggtagccagtggagctgtacggcttggagaa
aatggcaagatttgttgggtcacagagtga
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