| Entry |
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| Name |
(RefSeq) multidrug resistance-associated protein 1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
elk Enhydra lutris kenyoni (northern sea otter)
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| Pathway |
| elk04977 | Vitamin digestion and absorption |
| elk04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:elk00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
111156238
09132 Signal transduction
04071 Sphingolipid signaling pathway
111156238
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
111156238
04981 Folate transport and metabolism
111156238
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
111156238
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
111156238
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:elk02000]
111156238
Enzymes [BR:elk01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
111156238
Transporters [BR:elk02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
111156238
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1531 aa
MELRGFCSADGSDPFWAWDVTWNTSNPDFTKCFQNTFLVWVPCSYLWVCFPFYFLYLSRH
DRGYIQMTYLNKTKTALGFLLWIVCWADLFYSFWERSWGKFLAPVFLVSPTLLGITMLLA
TFLIQLERRKGVQSSGIMLTFWVVALLCALAIFRSKIMAALKEDAEIDVFRDVTFYIYFS
LVLMQLVLSCFSDRPPLFSETIHDPNPCPESSASFLSRVTFWWITGLMVRGYRQPLESTD
LWSLNKEDTSEQVVPVLVKNWKKECAKSKRQQAKMAYSSKDPAKPKGGSQVDVSEEAEVL
IVKSPQKEREPSLFKVLYKTFGPYFLMSFLFKAVHDLMMFAGPEILKLLINFVNDQEAPD
WQGYFYTVLLFVSACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTV
GEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSILAGVAVMILMVPVN
AVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDQVLAIRQEELKVLK
KSAYLAAVGTFTWVCTPFLVALSTFAVYVTIDKNNILDAQKAFVSLALFNILRFPLNILP
MVISSIVQASVSLKRLRIFLSHEELEPDSIERRTVKDGGGTNSITVKNATFTWARSDPPT
LSGITFSIPEGSLVAVVGQVGCGKSSLLSALLAEMDKMEGYVAVKGSVAYVPQQAWIQND
SLRENILFGRQLQERYYKAVIEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLAR
AVYCDSDIYLFDDPLSAVDAHVGKHIFENVIGPKGMLRNKTRLLVTHSISYLPQVDVIIV
MTGGKISEMGSYQELLARDGAFAEFLRTYASSEQEQTEQDEGLTSVSSPGKEGKQMENGM
LVTDVAGKQLQRQLSNSSSYSGDISHHHTSTAELQKAGAKNEDAWKLVEADKAQTGQVKL
SVYWDYMKAIGLFISFLSIFLFLCNHVAALASNYWLSLWTDDPIVNGTQEHTKVRLSVYG
ALGISQGISVFSYSMVVSIGGIFASRRLHLDLLHNVLRSPMSFFERTPSGNLVNRFSKEL
DTVDSMIPQVIKMFMGSLFNVIGACIIILLATPIASIIIPPLGLIYFFVQRFYVASSRQL
KRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLA
VRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVA
VERLKEYSETEKEAPWRVPEMTPPSTWPQVGRVEFRDYGLRYRENLDLVLRNINITIDGG
EKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDDINIAKIGLHDLRFKITIIPQDPVLF
SGSLRMNLDPFTQYSDEEVWTSLELAHLKDFVSALPDKLNHECAEGGENLSVGQRQLVCL
ARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVL
DKGEIRECGQPSDLLQQRGLFYSMAKDAGLV |
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| NT seq |
4596 nt +upstreamnt +downstreamnt
atggagctccgcggcttctgcagcgccgatggctccgaccccttctgggcgtgggatgtc
acgtggaacaccagcaaccctgacttcaccaagtgctttcagaacacgttcctcgtgtgg
gtgccttgctcctacctctgggtctgcttccccttctacttcctctatctctcacgccat
gaccggggctacattcagatgacctatctcaacaaaaccaaaactgccttgggatttttg
ctgtggattgtctgctgggcagacctcttctactctttctgggaaagaagttggggcaaa
ttcctggccccagtgtttctggtcagcccaaccctcttgggcatcactatgctgcttgct
acctttttaattcaactcgagagaagaaaaggagtccagtcctcggggatcatgctaact
ttctgggttgtagccctactgtgtgcccttgccatcttcagatccaaaatcatggctgcc
ttaaaagaggatgctgaaatcgacgtgtttcgcgatgtcactttctacatttacttttcc
ctcgtgctgatgcagctcgtgctgtcctgcttctcagaccgaccacccctgttctctgaa
accatccacgaccccaatccctgcccggagtccagcgcctccttcctttccagagtcacc
ttctggtggattacagggctgatggtccgcggctaccgccagccgctggagagcactgac
ctctggtccctgaataaggaggacacgtcagagcaagttgtgcccgttttggtaaagaac
tggaagaaggagtgtgccaaatccaaaaggcagcaggcgaagatggcgtactcctccaag
gatcccgccaagccaaaagggggctcgcaggtggatgtgagtgaggaggctgaggttttg
atcgtcaagtccccccagaaggagcgggagccgtctctgttcaaggtgttatacaagacc
ttcgggccctacttcctcatgagcttcttattcaaggccgtccacgacctgatgatgttt
gccggcccagagatcttaaaattgctcatcaacttcgtgaacgatcaggaggccccggac
tggcagggctacttctacaccgtgctgctgttcgtcagcgcctgcctccagaccctcgtg
ctgcaccagtacttccacatctgtttcgtcagcggcatgaggatcaagacagccgtcatt
ggtgctgtctaccggaaggccttggtgattaccaactcagccagaaagtcctccactgtc
ggggagattgtcaacctcatgtctgtggacgcccagaggttcatggacttggccacgtac
attaacatgatctggtcagctcctctgcaagtcatccttgctctctacctcctgtggctg
aacctgggcccgtccatcctggctggggtggctgtgatgatccttatggttcctgtcaat
gccgtgatggccatgaagaccaagacttaccaggtggcccacatgaagagcaaagacaat
cggattaagctgatgaatgagattctcaacgggatcaaagtgctcaagctttacgcctgg
gaacttgccttcaaggaccaggtgctggccatcaggcaggaggagctgaaggtgctcaag
aaatcggcctacctggcagccgtgggaaccttcacctgggtctgcacacctttcctggtg
gccctgtctacatttgccgtctacgtgaccatcgacaagaacaacatcctggatgcccag
aaagctttcgtgtccttggccttgttcaacatccttcgatttcccctgaatattctcccc
atggtcatcagcagcatcgtgcaggcgagtgtctccctcaaacgccttaggatcttcctg
tctcatgaggagctggagcccgacagtatcgagcgaaggacggtcaaagatggcgggggc
acaaacagcatcaccgtgaagaatgccacgttcacttgggccaggagtgaccctccgacg
ctaagtggcatcaccttctccattccggaaggttccttggtggccgtggtgggccaggtg
ggctgtggaaagtcgtctctgctctcagcactcctggccgagatggacaagatggaggga
tacgtggctgtcaagggctcagtggcctacgtcccccagcaggcctggattcagaatgat
tctctccgagaaaacatccttttcggccgccagctacaggaacggtattataaggccgtc
attgaagcctgtgccctcctcccagatctggaaatcctgcccagcggggaccggacagag
attggtgagaagggtgtgaacctgtctgggggccagaagcagcgagtgagcctggcccgg
gccgtgtactgtgactccgacatctacctctttgacgaccccctgtcagcagtggatgct
catgtgggaaaacacatatttgaaaacgtgattggtcctaaggggatgctgaggaacaag
acacggctcctggtcacgcacagcatcagctacctgccccaggtggatgtcatcatcgtc
atgaccggcggcaagatctcggagatgggctcctaccaggagctactggcccgggacggc
gccttcgccgagttcctgcgcacgtacgccagcagcgagcaggagcagactgagcaggat
gaagggttgacgagtgtcagcagtccagggaaggaggggaagcagatggagaatggcatg
ctggtgacggatgtcgcaggaaaacagctgcagagacagctcagcaactcctcctcctac
agcggggacattagccaccaccacaccagcacagctgagctgcagaaagccggggccaag
aacgaggacgcgtggaagctggtggaggcagacaaggcacaaacaggacaggtcaagctg
tctgtgtactgggactacatgaaggcgatcggacttttcatctcctttctgagcatcttc
cttttcctgtgtaaccatgttgctgctctggcctctaactattggctcagcctctggacc
gatgaccccatcgtcaacgggacccaggagcacactaaagtccggctgagcgtctacgga
gccctgggcatttcgcaaggtatctcagtgttcagctactccatggtggtgtccatcggg
ggcatcttcgcttcccgccgcctgcacctggacctgctacacaacgtcctccggtccccc
atgagcttcttcgagcgcacccccagcgggaacctggtgaaccgcttctccaaggagctg
gacacggtggactcgatgatcccgcaggtcatcaagatgttcatgggctccctgttcaac
gtcatcggcgcctgcatcatcatcctgctggccacacccatcgcctccatcatcatcccg
ccgctgggcctcatctacttcttcgtccagaggttctacgtggcctcgtcgcggcagctg
aagcgcctggagtcggtgagccgctccccggtgtactcccacttcaacgagaccctgctg
ggcgtcagcgtcatccgcgccttcgaggagcaggagcgcttcatccgccagagtgacctg
aaagtggacgagaaccagaaggcctattaccccagcatcgtggccaacaggtggctggct
gtgcggctggagtgtgtaggcaactgtatcgtcctgttcgctgccctgttcgccgtgatc
tccaggcatagtctcagcgccggcttggtgggcctgtctgtgtcatactcattgcaggtc
accacgtacttgaactggctggtccgcatgtcgtccgagatggagaccaacatcgtggcg
gtggagaggctgaaggagtattcagagacggagaaggaggctccctggcgagtcccggag
atgactccacccagcacctggcctcaggtgggccgagtggaattccgagactatggcctg
cgctaccgagaaaacctggacttggttctcaggaacatcaatatcaccatcgatggaggg
gaaaaggttggcatcgtggggcggacgggagccgggaagtcgtccctgaccctgggcttg
tttcgaatcaacgaatccgcagagggggagatcattatcgacgacatcaacattgccaag
atcggcctgcacgatctgcgcttcaagatcaccatcatcccacaggaccctgttttgttc
tcgggttccctccgcatgaacctggacccgttcacccagtactcagatgaggaagtgtgg
acgtccctggagctggctcacctgaaggacttcgtgtccgcccttcccgacaagctgaac
cacgagtgtgcggaaggcggggagaacctgagcgtcgggcagcgccagcttgtgtgcctg
gcccgggctctgctgaggaagaccaagatcctcgtgttggacgaggccacggcggccgtg
gacctcgaaacagacaacctcattcagtcgaccatccggacgcagtttgaagactgcacg
gtgctcactattgcacaccggctgaacaccatcatggactacacgagggtcatcgtcctg
gacaagggagagatccgggagtgcggccagccctccgacctcctacagcagagaggtctt
ttctacagcatggccaaagatgctggcctggtgtga |
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