KEGG   Enhydra lutris kenyoni (northern sea otter): 111156353
Entry
111156353         CDS       T05871                                 
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1
  KO
K05853  P-type Ca2+ transporter type 2A [EC:7.2.2.10]
Organism
elk  Enhydra lutris kenyoni (northern sea otter)
Pathway
elk04020  Calcium signaling pathway
elk04022  cGMP-PKG signaling pathway
elk04024  cAMP signaling pathway
elk04148  Efferocytosis
elk04260  Cardiac muscle contraction
elk04261  Adrenergic signaling in cardiomyocytes
elk04380  Osteoclast differentiation
elk04919  Thyroid hormone signaling pathway
elk04972  Pancreatic secretion
elk05010  Alzheimer disease
elk05017  Spinocerebellar ataxia
elk05022  Pathways of neurodegeneration - multiple diseases
elk05410  Hypertrophic cardiomyopathy
elk05412  Arrhythmogenic right ventricular cardiomyopathy
elk05414  Dilated cardiomyopathy
elk05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:elk00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    111156353
   04024 cAMP signaling pathway
    111156353
   04022 cGMP-PKG signaling pathway
    111156353
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    111156353
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    111156353
  09153 Circulatory system
   04260 Cardiac muscle contraction
    111156353
   04261 Adrenergic signaling in cardiomyocytes
    111156353
  09154 Digestive system
   04972 Pancreatic secretion
    111156353
  09158 Development and regeneration
   04380 Osteoclast differentiation
    111156353
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    111156353
   05017 Spinocerebellar ataxia
    111156353
   05022 Pathways of neurodegeneration - multiple diseases
    111156353
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    111156353
   05412 Arrhythmogenic right ventricular cardiomyopathy
    111156353
   05414 Dilated cardiomyopathy
    111156353
   05415 Diabetic cardiomyopathy
    111156353
Enzymes [BR:elk01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.10  P-type Ca2+ transporter
     111156353
SSDB
Motif
Pfam: Cation_ATPase Cation_ATPase_C E1-E2_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD
Other DBs
NCBI-GeneID: 111156353
NCBI-ProteinID: XP_022372849
UniProt: A0A2Y9KND7
LinkDB
Position
Unknown
AA seq 1042 aa
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKEKWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSIQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDSCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKDDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATTSCSLSACTDGISWPFVL
LIMPLVIWVYSTDTNFSDMFWS
NT seq 3129 nt   +upstreamnt  +downstreamnt
atggagaacgcgcacacaaagacggtggaggaggtgctgggccacttcggcgtcaacgag
agcacggggctgagcctggagcaggtcaagaagctcaaggagaaatggggttccaacgag
ttaccggctgaagaaggaaaaaccttgctggaacttgtgattgagcagtttgaagactta
ctagttagaattttattgctggcagcttgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaataacagcctttgtagaaccctttgtaattttacttatattagtagcc
aatgcaattgtgggtgtgtggcaggaaagaaatgctgagaatgcaatcgaagcccttaag
gaatatgagcctgaaatgggcaaagtataccgacaggacagaaagagtatccagcggatt
aaagctaaagacatagttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gctgatataagattaacttccatcaaatctactactctaagagttgaccagtctattctc
acaggcgagtctgtgtcggtcatcaagcacacggaccccgtcccggacccgcgggccgtc
aaccaagataagaagaacatgctcttttctggtacaaacattgctgctggcaaagccatg
ggagtggtggtggcaactggagtgaacacagaaattggcaagatccgggatgaaatggtg
gcaacagagcaggagagaaccccactccagcagaaactagatgaatttggggaacagctt
tccaaagtcatctccctgatttgcattgctgtctggatcataaacattgggcacttcaac
gacccagttcatggaggctcctggatcaggggtgctatttactacttcaaaattgcggtg
gctctggctgtggcagccattcctgaaggtctgcccgcggtcatcaccacctgcctggct
cttggaactcgcagaatggcaaagaaaaatgccattgttcgaagcctcccttctgtagaa
acccttggttgtacttctgttatctgctcggacaagactggtacgctgacaacgaaccag
atgtctgtgtgcaggatgttcattctggacaaagttgaaggtgatagctgttcccttaat
gagtttaccattactggatcaacttacgcacctattggagaagtgcataaagacgataag
ccggttaagtgtcatcagtatgacggtctcgtggaactggccacaatttgcgctctttgt
aacgattccgccttggattacaatgaggcaaagggtgtgtatgaaaaagttggagaagct
acagagactgctctcacttgcctagtggagaagatgaatgtatttgataccgaattgaag
ggtctttctaaaatagagcgagcaaatgcctgcaactcggtcatcaagcagttgatgaaa
aaggaatttactctggagttttcacgtgatagaaagtcgatgtcagtttattgtacacca
aacaaaccaagccggacatcgatgagcaaaatgtttgtgaagggtgctcccgaaggcgtc
atcgacaggtgcacccacattcgagttggaagtacgaaagttcctatgaccccgggagtc
aaacagaagatcatgtctgtcattcgggaatggggtagtggcagcgacacactgcggtgc
ctggctctggccactcacgacaacccactgagaagagaagaaatgaacctggaggactct
gccaactttattaaatacgagaccaatctgactttcgttggctgcgtgggcatgctggac
cctccaagaattgaagtggcctcttctgtgaagctgtgccggcaagcaggcatccgggtc
atcatgatcacgggggacaacaagggcactgcagtggccatctgtcggcgcattggcatc
ttcgggcaggacgaggatgtgacttcaaaggcttttacgggtcgagagtttgatgagctc
aatccttcagcccagagagatgcctgtttgaatgctcgctgttttgctcgagttgaacct
tcccacaagtcaaaaattgtagaatttcttcagtcttttgatgagattacagctatgact
ggggacggcgtgaatgatgctcccgccctgaagaaatctgagatcggcattgccatgggc
tctggcacggcagtggctaaaacggcctcagagatggtgctggccgacgacaacttttcc
accatcgtggctgcggtggaggaggggcgcgccatctacaacaacatgaagcagttcatc
cgctatctcatctcctccaatgtgggggaagtggtctgtatcttcctgacagcagccctt
ggctttcctgaggctttaattcctgtccagctgctctgggtcaatctggtgacagacggc
ctgcctgccactgccctggggttcaacccacccgacctggacatcatgaacaaaccaccc
cggaacccgaaggaacccctgatcagtggatggctctttttccgttacctggccattggc
tgttacgttggcgcagctaccgtgggtgctgccgcgtggtggttcattgctgccgacgga
gggccaagggtgtccttctaccagctgagccacttcctacagtgtaaagatgacaacccg
gactttgaaggagtggattgtgcaatctttgagtccccatacccgatgacaatggcgctg
tctgttctagtaaccatagagatgtgtaacgccctcaacagcttgtccgaaaaccagtcc
ctgctgaggatgcccccctgggagaacatctggctcgtgggctccatctgcctgtccatg
tcgctccacttcctcatcctctacgtggaacctttgccacttattttccagatcacaccg
ctgaatctgacccagtggctgatggtgctgaaaatctccttgcctgtgattctgatggac
gagacgctcaagtttgtggcccgcaactacctggaacctggtaaagagtgtgtgcagcct
gccaccacgtcctgctcgctctcggcatgcaccgacgggatttcctggccgtttgtgctg
ctcataatgcccctggtgatctgggtctatagcacagacactaactttagtgatatgttc
tggtcttga

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