KEGG   Enhydra lutris kenyoni (northern sea otter): 111161210
Entry
111161210         CDS       T05871                                 
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4 isoform X1
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
elk  Enhydra lutris kenyoni (northern sea otter)
Pathway
elk04010  MAPK signaling pathway
elk04012  ErbB signaling pathway
elk04620  Toll-like receptor signaling pathway
elk04664  Fc epsilon RI signaling pathway
elk04668  TNF signaling pathway
elk04912  GnRH signaling pathway
elk04926  Relaxin signaling pathway
elk04935  Growth hormone synthesis, secretion and action
elk04936  Alcoholic liver disease
elk05132  Salmonella infection
elk05135  Yersinia infection
elk05142  Chagas disease
elk05161  Hepatitis B
elk05166  Human T-cell leukemia virus 1 infection
elk05167  Kaposi sarcoma-associated herpesvirus infection
elk05169  Epstein-Barr virus infection
elk05208  Chemical carcinogenesis - reactive oxygen species
elk05417  Lipid and atherosclerosis
elk05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:elk00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    111161210
   04012 ErbB signaling pathway
    111161210
   04668 TNF signaling pathway
    111161210
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    111161210
   04664 Fc epsilon RI signaling pathway
    111161210
  09152 Endocrine system
   04912 GnRH signaling pathway
    111161210
   04926 Relaxin signaling pathway
    111161210
   04935 Growth hormone synthesis, secretion and action
    111161210
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    111161210
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    111161210
   05161 Hepatitis B
    111161210
   05167 Kaposi sarcoma-associated herpesvirus infection
    111161210
   05169 Epstein-Barr virus infection
    111161210
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    111161210
   05135 Yersinia infection
    111161210
  09174 Infectious disease: parasitic
   05142 Chagas disease
    111161210
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    111161210
   05418 Fluid shear stress and atherosclerosis
    111161210
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    111161210
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:elk01001]
    111161210
Enzymes [BR:elk01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     111161210
Protein kinases [BR:elk01001]
 Serine/threonine kinases: STE group
  STE7 family
   111161210
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 111161210
NCBI-ProteinID: XP_022380497
UniProt: A0A2Y9L2M8
LinkDB
Position
Unknown
AA seq 400 aa
MAAPSPSGGGGGSGGGSGSGTPGPVGPPAPGHPAVSSMQGKRKALKLNFANPPFKSTARF
TLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKM
VHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICME
LMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDR
SGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYE
LATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYK
ELLKHPFILMYEERTVEVACYVCKILDQMPATPSSPMYVD
NT seq 1203 nt   +upstreamnt  +downstreamnt
atggcggctccgagcccgagcggcggcggcggcggctccgggggcggcagcggcagcggc
accccgggccccgtggggcccccggcgccgggccacccggccgtcagcagcatgcagggt
aaacgcaaagcactgaagttgaattttgcaaatccacctttcaaatctacagcaaggttt
actctgaatcccaaccctacaggagttcaaaacccacacatagagagactgagaacacac
agcattgaatcgtcaggaaaactgaagatctcccctgagcagcactgggatttcactgcg
gaggacttgaaagaccttggagaaattggacgaggagcttatggttctgtcaacaaaatg
gtccacaaaccaagtgggcaaataatggcagttaaaagaattcggtcaacagtggatgaa
aaagaacaaaaacaacttcttatggatttggatgtagtaatgcggagtagtgattgcccg
tacattgttcagttttatggtgcactcttcagagagggtgactgttggatctgtatggaa
ctcatgtctacctcgtttgataagttttacaaatatgtatatagtgtattagatgatgtt
attccagaagaaattttaggcaaaatcactttagcaactgtgaaagcactaaaccactta
aaagaaaacttgaaaatcattcacagagatatcaaaccttccaatattcttctggacagg
agtggaaatattaagctctgtgactttggcatcagcggacagctggtggactccattgcc
aagacaagagatgctgggtgtaggccttacatggcacctgaaagaatagacccgagcgcg
tcacgacaaggatatgacgtccgctctgatgtctggagtttggggatcacattgtacgag
ttagccacaggccggtttccttacccgaagtggaacagtgtgttcgatcagctcacgcaa
gtcgtgaaaggggaccctccgcagctgagcaactccgaagaacgcgagttctccccgagc
ttcatcaacttcgtcaacttgtgccttacgaaggatgaatccaaaaggccaaagtataaa
gaacttctgaaacatccctttattttgatgtatgaagaacgtaccgtcgaggtcgcctgc
tatgtttgtaagatcctggatcagatgccagcgactcccagctctcccatgtatgtcgac
tga

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