KEGG   Escherichia coli W: WFL_19950
Entry
WFL_19950         CDS       T02101                                 
Symbol
rffG
Name
(GenBank) dTDP-glucose 4,6-dehydratase
  KO
K01710  dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
Organism
ell  Escherichia coli W
Pathway
ell00521  Streptomycin biosynthesis
ell00523  Polyketide sugar unit biosynthesis
ell00525  Acarbose and validamycin biosynthesis
ell00541  Biosynthesis of various nucleotide sugars
ell01100  Metabolic pathways
ell01110  Biosynthesis of secondary metabolites
ell01250  Biosynthesis of nucleotide sugars
Module
ell_M01025  dTDP-D-Fuc4NAc biosynthesis, Glc-1P => dTDP-D-Fuc4NAc
Brite
KEGG Orthology (KO) [BR:ell00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 Biosynthesis of various nucleotide sugars
    WFL_19950 (rffG)
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    WFL_19950 (rffG)
   01055 Biosynthesis of vancomycin group antibiotics
    WFL_19950 (rffG)
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    WFL_19950 (rffG)
   00525 Acarbose and validamycin biosynthesis
    WFL_19950 (rffG)
Enzymes [BR:ell01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.46  dTDP-glucose 4,6-dehydratase
     WFL_19950 (rffG)
SSDB
Motif
Pfam: GDP_Man_Dehyd Epimerase Polysacc_synt_2 3Beta_HSD RmlD_sub_bind NAD_binding_4 adh_short Sacchrp_dh_NADP KR
Other DBs
NCBI-ProteinID: AFH13634
UniProt: E0J404
LinkDB
Position
4193435..4194502
AA seq 355 aa
MRKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKVDI
CDRAELARVFTEHQPDCVMHLAAESHVDRSIDGPAAFIETNIVGTYTLLEAARAYWNALT
EDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLVRAWLRTYGL
PTLITNCSNNYGPYHFPEKLIPLMILNALAGKSLPVYGNGQQIRDWLYVEDHARALYCVA
TTGKVGETYNIGGHNERKNLDVVETICELLEELAPNKPHGVAHYRDLITFVADRPGHDLR
YAIDASKIARELGWLPQETFESGMRKTVQWYLANESWWKQVQDGSYQGERLGLKG
NT seq 1068 nt   +upstreamnt  +downstreamnt
atgagaaagattctgataacaggtggtgccgggtttattggctcggcgctggtgcgttat
atcatcaacgaaacgagcgatgcggtggtagtggtcgataagctgacctacgccggaaac
ctgatgtcgctggcaccggtcgcgcaaagcgagcgctttgcctttgagaaagttgatatc
tgcgatcgggcagaactggcgcgcgtattcactgagcatcagccagactgtgtcatgcat
ctggcagccgaaagccatgttgaccgttctattgacggcccggcagcgtttattgaaacc
aacattgtcgggacttatacattgcttgaagcggcgcgggcttactggaatgcgctaacg
gaagataaaaaatcagcgttccgttttcatcatatctccactgacgaagtatatggtgac
ctgcactcgacggatgatttcttcaccgaaaccacgccgtatgcgccgagcagcccttat
tccgcgtcaaaagccagcagcgaccatctggtgcgcgcctggctgcggacctatggtctg
ccgacgcttatcaccaactgctcgaataactacggcccttaccactttccggaaaaactg
atcccgctgatgatcctcaacgcgctggcgggtaaatcgctgccggtatatggcaacggg
cagcaaatccgtgactggctgtatgtggaagatcacgcccgcgcgctgtattgcgtggcg
accaccgggaaagtcggtgaaacctataatattggtggtcacaacgagcgtaagaatctc
gatgttgtggaaaccatttgcgagctgctggaagaactggctccgaacaagccgcacggc
gtggcgcactatcgtgacctgatcacctttgtcgctgaccgtccggggcatgatctgcgc
tatgccattgatgcttcgaaaattgcccgtgaacttggctggctgccgcaggaaaccttt
gaaagtggaatgcgtaaaacggtgcagtggtatctggctaatgaaagctggtggaagcag
gtgcaggacggcagctatcagggcgagcgtttaggtctgaaaggctaa

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