Eubacterium callanderi: ELI_2530
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Entry
ELI_2530 CDS
T01336
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
elm
Eubacterium callanderi
Pathway
elm00300
Lysine biosynthesis
elm00550
Peptidoglycan biosynthesis
elm01100
Metabolic pathways
elm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
elm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ELI_2530
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ELI_2530
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ELI_2530
Enzymes [BR:
elm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ELI_2530
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ADO37512
UniProt:
E3GE17
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All DBs
Position
complement(2347469..2348830)
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AA seq
453 aa
AA seq
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MEKISLEQLVKITEGRLIQTGTTDWISGAAIDSRKIEENDLFIPIKGEKADGHCFIKIAA
EKGCSTSFTETEALDFPEGISVVLVESCLEAMKALAKYNRERYDIPVIAVTGSSGKTTTK
DLIASVLSQKYKTLKTQGNFNNEYGIPQTLFNLQPEHEIAVIEMGMDHLDDIRKSIGEVR
PHISVITNIGTAHIEILKTQDNILAAKKEIFETMGPGDIALLNGDDVYLNKIKEDEEPFS
VVRVGIKGEDLSLKAEQVDSSAQGIRFVADGEHFHFAYPGIHNVYNCLTAIWLGRYYQMT
HEEIQRGLDAFKPSGNRMDIVRVREATVINDSYNANPDAMKAALDMLWDMGKSCRRLAVL
GDMLEMGEMAESGHLEIGAYAAEKADVLIAVGPESKAYIKGAGASLADERCFWTADAEGA
GKLLRKLMAPGDVILIKASRGVHLEKTLKMIQE
NT seq
1362 nt
NT seq
+upstream
nt +downstream
nt
atggaaaaaatttcacttgaacaactggtgaaaatcacagaaggccggctcatccagaca
ggaacaaccgactggatcagcggcgcggccatcgatagccgtaaaatcgaagaaaatgat
ctttttatccccattaagggtgaaaaggcagatggacactgtttcatcaaaatcgcagct
gaaaaaggctgttcaacaagctttacagagacagaagctctggattttccagaggggatc
agcgtcgttctggtcgaatcttgcctggaagccatgaaggccctggcgaagtacaaccgg
gagcgctatgatataccggtcatcgccgttaccggcagcagcggaaagaccacaaccaag
gacctcatcgcttcagtgttgtcccagaaatacaagaccctgaaaacccaggggaatttc
aataatgaatacggcatcccccagacactctttaacttacagccagagcacgaaatcgcc
gtgatcgagatgggcatggaccatctcgatgatatccgtaaatccatcggtgaggtcaga
ccccatatcagcgtcattaccaatatcggcacagcccatatcgaaatcctgaaaacccag
gacaacatcctggccgccaaaaaagagatcttcgagaccatgggtcccggcgacattgcg
ctgctcaacggggatgatgtgtatttaaataagatcaaagaggatgaagaacccttctcg
gttgtccgggtggggattaaaggtgaggatctgtcacttaaggcagaacaggtcgattcc
tccgctcagggcatccgctttgtagcagatggcgaacacttccacttcgcttatcctggc
attcacaatgtttacaactgcctgaccgccatctggctcggcagatattatcagatgacc
catgaagagattcagcgcgggctcgacgcctttaaaccaagcggcaaccgcatggatatc
gtcagggtaagagaggccacggtcattaacgattcctataacgccaaccccgacgccatg
aaggcagctctcgatatgctgtgggatatggggaaaagctgccgcaggctcgcggtgctc
ggcgatatgctggaaatgggcgagatggctgaaagcgggcacctcgagatcggtgcttac
gcggcagagaaggccgatgtgctcattgcggtgggaccggaatcaaaagcctacatcaag
ggggcaggcgccagcctggcagatgaacgatgcttctggactgccgacgcagagggcgct
ggaaagctgctgagaaagcttatggcgccgggagacgtgattctcatcaaggcctccagg
ggcgtgcatctggaaaaaacactaaaaatgattcaggagtaa
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