Escherichia coli O83 H1 NRG 857C (AIEC): NRG857_00380
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Entry
NRG857_00380 CDS
T02068
Name
(GenBank) isopropylmalate isomerase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
eln
Escherichia coli O83:H1 NRG 857C (AIEC)
Pathway
eln00290
Valine, leucine and isoleucine biosynthesis
eln00660
C5-Branched dibasic acid metabolism
eln01100
Metabolic pathways
eln01110
Biosynthesis of secondary metabolites
eln01210
2-Oxocarboxylic acid metabolism
eln01230
Biosynthesis of amino acids
Module
eln_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
eln00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
NRG857_00380
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NRG857_00380
Enzymes [BR:
eln01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
NRG857_00380
4.2.1.35 (R)-2-methylmalate dehydratase
NRG857_00380
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Gene cluster
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Motif
Pfam:
Aconitase
Spo0M
Motif
Other DBs
NCBI-ProteinID:
ADR25507
UniProt:
A0A0H3EEX8
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Position
complement(81017..82417)
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AA seq
466 aa
AA seq
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MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFAT
MDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITA
KDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTF
NYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISV
NDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAE
IAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNP
GERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atggctaagacgttatacgaaaaattattcgacgctcacgtagtgtacgaagccgaaaac
gaaaccccgctgttatatatcgaccgccacctggtgcatgaagtgacctcaccgcaggcg
ttcgatggtctgcgcgcccacggtcgcccggtacgtcagccgggcaaaaccttcgccacc
atggatcacaacgtctctactcagacgaaagacattaatgcctgcggtgaaatggcgcgc
atccagatgcaggagctgatcaaaaactgcaaagaatttggcgtcgagctgtatgacctg
aatcacccgtatcaggggatcgtccacgtaatggggccggaacagggcgtgaccttgccg
gggatgaccattgtctgcggcgactcacataccgccacccacggcgcgtttggcgcactg
gcctttggtatcggcacttccgaagttgaacacgtactggcaacgcaaaccctgaaacag
ggccgggcgaagaccatgaaaattgaagtccagggcaaagccgcgccgggcattaccgca
aaagatatcgtgctggcaattattggtaaaaccggcagcgcaggcggtaccgggcatgtg
gtggaattttgcggcgaagcaatccgtgatttaagcatggaaggtcgtatgaccctgtgc
aatatggcaatcgaaatgggcgcaaaagccggtctggttgcaccggacgaaaccaccttt
aactatgttaaaggccgtctgcatgcgccgaaaggcaaagatttcgacgacgccgttgcc
tactggaaaaccctgcaaaccgacgaaggagcaactttcgataccgttgtcactctgcaa
gcagaagagatttcgccgcaggtcacctggggcaccaatccaggccaggtgatttctgtg
aacgacaatattcccgatccggcttcgtttgccgatccggttgaacgcgcgtcggcagaa
aaagcgctggcctatatggggctgaaaccgggtattccgctgacagaagtggctatcgac
aaagtgtttattggttcctgtactaactcgcgtattgaagatttacgcgcggcagcggaa
atcgccaaaggccggaaagtcgcgccaggcgtacaagcgctggtggttcccggctccggt
ccggttaaagcccaggcggaagcggaaggtctggacaaaatttttatcgaagctggtttt
gaatggcgcttgccaggttgttcaatgtgcctggcgatgaacaacgaccgcctgaatccg
ggcgaacgttgcgcctccaccagcaaccgtaactttgaaggccgccaggggcgcggcggg
cgcacgcatctggtcagtccggcaatggctgccgccgcggctgtgaccggacatttcgcc
gacattcgcaacattaaataa
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