KEGG   Escherichia coli O44 H18 042 (EAEC): EC042_0572
Entry
EC042_0572        CDS       T02067                                 
Symbol
folD
Name
(GenBank) bifunctional protein FolD [includes: methylenetetrahydrofolat dehydrogenase; methenyltetrahydrofolate cyclohydrolase]
  KO
K01491  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
Organism
elo  Escherichia coli O44:H18 042 (EAEC)
Pathway
elo00670  One carbon pool by folate
elo00720  Other carbon fixation pathways
elo01100  Metabolic pathways
elo01120  Microbial metabolism in diverse environments
elo01200  Carbon metabolism
elo01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:elo00001]
 09100 Metabolism
  09102 Energy metabolism
   00720 Other carbon fixation pathways
    EC042_0572 (folD)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    EC042_0572 (folD)
Enzymes [BR:elo01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     EC042_0572 (folD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     EC042_0572 (folD)
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-ProteinID: CBG33399
UniProt: D3GW77
LinkDB
Position
complement(644892..645758)
AA seq 288 aa
MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEE
VGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDV
DGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELL
LAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKV
VGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQGE
NT seq 867 nt   +upstreamnt  +downstreamnt
atggcagcaaagattattgacggtaaaacgattgcgcagcaggtgcgctctgaagttgct
caaaaagttcaggcgcgtattgcagccggactgcgggcaccaggactggccgttgtgctg
gtgggtagtaaccctgcatcgcaaatttatgtcgcaagcaaacgcaaggcttgtgaagaa
gtcgggttcgtctcccgctcttacgacctcccggaaaccaccagcgaagcggagctgctg
gagcttatcgatacgctgaatgccgacaacaccatcgatggcattctggttcaactgccg
ttaccggcgggtattgataacgtcaaagtgctggaacgaattcacccggacaaagacgta
gacggtttccatccttataacgtcggtcgcctgtgccagcgcgcgccgcgtctgcgtccc
tgcaccccgcgcggtattgtcacgctgcttgagcgttacaacattgataccttcggcctc
aacgccgtggtgattggcgcatcgaatatcgttggccgcccgatgagcatggaactgcta
ctggcaggttgcaccaccaccgtgactcaccgtttcactaaaaatctgcgtcaccacgta
gaaaatgccgatctattgatcgttgccgtcggtaagccaggctttattcccggtgactgg
atcaaagaaggcgcaattgtgattgatgtcggcatcaaccgtctggaaaatggcaaagtt
gtgggcgacgtcgtgtttgaagacgcggctaaacgcgcctcatacattacgcctgttccc
ggcggcgttggcccgatgacggttgccacgctaattgaaaacacgctacaggcgtgcgtt
gaatatcatgatccacagggtgagtaa

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