KEGG   Escherichia coli O44 H18 042 (EAEC): EC042_2508
Entry
EC042_2508        CDS       T02067                                 
Symbol
menD
Name
(GenBank) menaquinone biosynthesis protein [includes: 2-succinyl-6-hydroxy 2,4-cyclohexadiene-1-carboxylate synthase; 2-oxoglutarate decarboxylase]
  KO
K02551  2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:2.2.1.9]
Organism
elo  Escherichia coli O44:H18 042 (EAEC)
Pathway
elo00130  Ubiquinone and other terpenoid-quinone biosynthesis
elo01100  Metabolic pathways
elo01110  Biosynthesis of secondary metabolites
elo01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:elo00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00130 Ubiquinone and other terpenoid-quinone biosynthesis
    EC042_2508 (menD)
Enzymes [BR:elo01000]
 2. Transferases
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.9  2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
     EC042_2508 (menD)
SSDB
Motif
Pfam: TPP_enzyme_M_2 TPP_enzyme_N TPP_enzyme_C
Other DBs
NCBI-ProteinID: CBG35340
UniProt: D3H1D2
LinkDB
Position
complement(2651964..2653634)
AA seq 556 aa
MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGH
LALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAI
RQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDD
TGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALW
AQTLGWPLIGDVLSQTGQPLPCADLWLSNAKAISELQQAQIVVQLGSSLTGKRLLQWQAS
CEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLEQHPAEKRQPWCVEIPRLAEQAMQAV
IARRDAFGEALLAHRISDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDG
LLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPT
PKNERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETALADAWRTPTTTVIEMVVNDT
DGAQTLQQLLAQVSHL
NT seq 1671 nt   +upstreamnt  +downstreamnt
atgtcagtaagcgcatttaaccgacgctgggcggcggtcattctggaagcattaacgcgt
cacggcgtcagacacatctgtatcgcccctggctcgcgttctacaccgttaacgttagcg
gcggcggagaattccgcattcattcaccacacccatttcgatgagcgcggactagggcat
ctggcgctggggctggcgaaagtcagcaagcagccggtggcggtgattgtgacctccggc
acggcggtagcaaatctctatccggcactgatagaagccgggttaaccggagaaaaactg
atcctgttaaccgccgatcgcccgccggagctaattgactgcggcgcgaatcaggcgatt
cgtcagccgggaatgttcgcctctcaccctacgcacagtatttcactgccgcgcccgacc
caggatatccccgcacgttggctggtttctaccatcgaccacgctctcggtacgcttcat
gctggtggagtccatatcaactgcccgtttgctgaaccgctgtatggcgaaatggacgac
accgggcttagctggcaacagcggctgggcgactggtggcaggacgacaaaccgtggctg
cgtgaagcgcctcgtctggaaagtgaaaaacagcgcgactggttcttctggcggcaaaag
cgcggcgtggtggttgccgggcgcatgagtgcggaagagggcaaaaaagttgcactgtgg
gcgcaaactcttggctggccgctgatcggtgatgtgctgtcgcaaaccgggcagccgctg
ccgtgtgccgatctctggttaagcaatgccaaagcgatcagcgaactgcaacaggcgcaa
attgtggtgcaactgggaagcagcctgacgggcaaacggctcctgcaatggcaggcaagc
tgtgaacccgaagagtactggattgttgatgacattgaagggcgacttgatccggcacac
catcgcggacgtcgcttaattgccaatattgccgactggctggagcaacatccggcagaa
aaacgccagccctggtgcgttgaaatcccgcgcctggcggaacaggcaatgcaggcggtt
attgcccgtcgcgatgcgtttggcgaagccctactggcgcatcgcatcagcgactatcta
cctgaacaggggcaattgtttgtcggtaacagcctggtggtacgtctgattgatgcgctt
tcgcaacttccggcaggttacccggtgtacagcaaccgtggtgccagcggtatcgacggg
ctgctctcgaccgccgcaggcgttcagcgggcaagcggcaaaccgacgctggcgattgtg
ggcgatctctcagctctttacgatctcaacgcgctggcgttattacgtcaggtttccgcg
ccgctggtattaattgtggtgaacaacaacggcgggcaaattttctcgctgttgccaacg
ccgaaaaacgagcgcgagcgtttctatctgatgccgcaaaacgtccattttgagcacgcc
gccgcgatgttcgagctgaaatatcatcgtccgcaaaactggcaggaacttgaaactgca
cttgccgacgcctggcgcacgccgaccaccacggtaattgaaatggtggttaacgacacc
gatggtgcgcaaaccctccagcaactgctggcgcaggtaagccatttatga

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