Escherichia coli O44 H18 042 (EAEC): EC042_2761
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Entry
EC042_2761 CDS
T02067
Symbol
purL
Name
(GenBank) Phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
elo
Escherichia coli O44:H18 042 (EAEC)
Pathway
elo00230
Purine metabolism
elo01100
Metabolic pathways
elo01110
Biosynthesis of secondary metabolites
Module
elo_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
elo00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
EC042_2761 (purL)
Enzymes [BR:
elo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
EC042_2761 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
CBG35594
UniProt:
D3H3R7
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All DBs
Position
complement(2946164..2950048)
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AA seq
1294 aa
AA seq
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MEILRGSPALSAFRINKLLARFQAARLPVHTIYAEYVHFADLNAPLNDDEHAQLERLLKY
GPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLTN
EQWQQVTAVLHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGLA
LAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFKMI
KNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPTA
ISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIVT
ALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNIR
ADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERRC
QEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPLE
IWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDLP
LDVLLGKTPKMTREVQTLKAKGDALVREGITIADAVKRVLHLPTVAEKTFLVTIGDRSVT
GMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEALT
NIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSM
KTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGAT
ALAQVYRQLGDKPADVRDVAQLKGFYDAVQALVAQRKLLAYHDRSDGGLLVTLAEMAFAG
HCGIDADIATLGDDRLAALFNEELGAVIQVRAADRKAVEAVLALHGLADCVHYVGQAVSG
DRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVKL
SFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRTG
LEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMM
SNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRV
EVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPHP
ERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3885 nt
NT seq
+upstream
nt +downstream
nt
atggaaattctgcgtggttcgcctgcattgtcggcattccgaatcaacaaactgctggca
cgttttcaggctgccaggctcccggttcacactatttacgccgagtatgtccattttgct
gacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaatat
ggcccggcactcgccagccacgccccgcaaggcaaactcctgctggtgaccccgcgtcct
ggcaccatctctccctggtcttcgaaagcgaccgatattgcccataactgcgggctgcaa
caggtaaaccgtcttgagcgcggcgtggcttactatatagaagccggtacgctgaccaat
gaacaatggcagcaagttaccgctgtactgcacgaccgcatgatggaaacggtctttttt
gctttagatgatgcagagcagctgtttgcacaccatcaaccgactccggtcaccagcgtt
gatttgctgggacagggccgtcaggcgctaatcgacgctaacctgcgtcttggcctggca
ctggcggaagatgaaatcgactatctgcaggatgctttcacaaagcttggtcgtaacccg
aacgacatcgagctgtatatgttcgctcaggcgaactctgagcactgccgccacaaaatt
tttaacgccgactggattatcgacggtgaacagcagccgaaatcgctgttcaagatgatc
aaaaataccttcgaaactacgccggatcacgttctctctgcttataaagataacgccgcc
gtcatggaagggtctgaagtgggccgctactttgctgaccacgaaacgggccgctacgat
ttccatcaggaaccggcgcatattctgatgaaagtcgaaactcacaaccacccgacggcg
atttctccgtggccgggcgcggcgaccggttccggcggtgaaatccgcgatgaaggtgcc
accgggcgtggcgcaaagccgaaagctggtctggtaggtttctccgtttccaacctgcga
attccaggcttcgaacagccgtgggaagaagatttcggtaagcctgagcgcattgtcacc
gcgctggacatcatgaccgaaggcccgctgggcggcgcggcatttaacaacgaatttggt
cgtccggcactgaacggctacttccgtacttatgaagaaaaagtgaacagccacaatggc
gaagagctgcgcggttatcacaaaccgatcatgctggcgggcgggatcggcaatattcgt
gccgatcacgtacaaaaaggcgagatcaacgttggtgcgaagctggtcgttctcggcggc
ccggcaatgaacatcggtcttggcggcggcgcggcgtcttccatggcgtctggtcagtct
gatgccgacctcgacttcgcttccgtacagcgcgacaacccggagatggagcgtcgctgc
caggaagtgatcgaccgttgctggcagcttggtgatgccaacccaatcctgtttatccac
gacgttggcgcaggcggtctttctaacgccatgccggaactggtgagcgacggcgggcgc
ggcggtaaattcgaactgcgcgatatcctgagcgacgaaccgggcatgagcccgctggaa
atctggtgtaacgaatcccaggaacgctacgtgctggcggttgctgccgatcagttaccg
ctgtttgacgaactgtgtaagcgtgagcgcgcgccatacgcggtgattggtgaagcgacc
gaagaactgcatctttctttgcacgatcgtcattttgataatcagccgatcgatctgccg
ctggacgtactgcttggtaaaacgccgaagatgacccgcgaagtacaaacgctgaaagcg
aagggtgatgcgctggttcgtgaagggattaccattgctgacgcggtgaaacgcgtgctg
cacctgccgaccgtggcggagaaaactttcctggtgaccattggtgaccgcagcgtaacc
ggcatggtagcgcgcgatcagatggtgggtccgtggcaggtgccggtcgctaactgcgcg
gtcactaccgccagccttgacagctactatggtgaagcgatggcgattggcgagcgtgcg
ccggttgcgctgctggatttcgccgcctctgcccgtctggcggtcggtgaagcgttaacc
aatattgccgcaacacagattggcgatatcaaacgcattaaactttccgccaactggatg
gcggcggcaggccaccctggtgaagatgcgggcctgtatgaagccgttaaagctgtgggc
gaagaactttgtccggcgctgggcctgacgatcccggtgggtaaagactctatgtcgatg
aaaacccgctggcaggaaggtaacgaagagcgcgaaatgacgtcgccgctgtcgctggtg
atttctgcatttgcccgtgtggaagatgtgcgtcacaccatcacgccgcagctttctacc
gaagataacgcattactgctgattgatctgggcaaaggcaataacgcgctgggcgcaacg
gcgctggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgacgtcgcg
caactgaaaggtttctatgacgcggttcaggcgctggtagcacagcgtaagctgctcgcg
taccacgaccgctctgatggcggcctgctggtaacgctggcggaaatggcctttgctggt
cattgcggcattgacgcggatatcgccactctgggtgacgatcgcctggcggcgttgttt
aacgaagaactgggtgcggtgattcaggttcgagccgctgaccgtaaagcagttgaagcg
gtactggcactgcatggccttgctgattgcgtccattatgttggccaggcggtttccggt
gaccgttttgtgattaccgccaacgggcagactgtattcagcgaaagccgcaccacgttg
cgtgtctggtgggcagaaactacctggcagatgcagcgcctgcgtgacaaccctgaatgt
gccgatcaggaacatcaggcgaaatccaacgacgccgatccgggcctgaatgtgaaactg
tcgttcgatatcaacgaagatgtggcagcaccgtatattgctactggcgcacgtccgaaa
gttgccgtactgcgtgagcagggcgtgaactcgcatgttgaaatggcggctgctttccac
cgtgcaggcttcgatgcaatcgatgtgcatatgagtgacctgctggctggacgcacgggc
ctggaggatttccacgccctggtcgcgtgcggtggtttctcctacggtgatgtgctgggt
gccggtgaaggttgggcgaagtctatcctgttcaatgaccgtgtacgcgatgagtttgca
accttcttccaccgtccgcaaacgctggcgctgggggtatgtaacggttgccagatgatg
tctaatctgcgcgaactgatcccaggtagtgagttgtggccacgttttgtgcgcaatacc
tccgatcgctttgaagcgcgtttcagcctggttgaagtaacccaaagcccgtctctgctg
ttgcaggggatggtgggctcgcaaatgccgattgctgtatctcatggtgaagggcgcgtg
gaagtgcgtgatgcggcgcatctggcggcactggaaagcaaagggctggtggcactgcgc
tatgtcgataacttcggcaaagtcactgaaacctacccggctaacccgaacggttctccg
aatggtattacggcagtcacgactgaaagtggtcgagtcaccattatgatgccgcacccg
gaacgtgttttccgtactgtcagcaactcctggcatccggaaaactggggcgaggatggc
ccatggatgcgcattttccgcaatgcgcgtaagcagttggggtaa
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