Escherichia coli O44 H18 042 (EAEC): EC042_4149
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Entry
EC042_4149 CDS
T02067
Symbol
ilvD
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
elo
Escherichia coli O44:H18 042 (EAEC)
Pathway
elo00290
Valine, leucine and isoleucine biosynthesis
elo00770
Pantothenate and CoA biosynthesis
elo01100
Metabolic pathways
elo01110
Biosynthesis of secondary metabolites
elo01210
2-Oxocarboxylic acid metabolism
elo01230
Biosynthesis of amino acids
Module
elo_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
elo_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
elo00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
EC042_4149 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
EC042_4149 (ilvD)
Enzymes [BR:
elo01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
EC042_4149 (ilvD)
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Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
CBG36976
UniProt:
D3H3Y1
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Position
4419043..4420893
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AA seq
616 aa
AA seq
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MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLV
AEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCIS
NCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDSQ
SDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIV
ELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSD
IDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQT
LEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDSLDDDRANGCIRSLEHAYSKDG
GLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRY
EGPKGGPGMQEMLYPTSFLKSMGLGKVCALITDGRFSGGTSGLSIGHVSPEAASGGSIGL
IEDGDLIAIDIPNRGIQLQVSDAELAARREAQEARGDKAWTPKNRERQVSFALRAYASLA
TSADKGAVRDKSKLGG
NT seq
1851 nt
NT seq
+upstream
nt +downstream
nt
atgcctaagtaccgttccgccaccaccactcatggtcgtaatatggcgggtgctcgtgcg
ctgtggcgcgccaccggaatgaccgacgccgatttcggtaagccgattatcgcggttgtg
aactcgttcacccaatttgtaccgggtcacgtccatctgcgcgatctcggtaaactggtc
gccgaacaaattgaagcggctggcggcgttgccaaagagttcaacaccattgcggtggat
gatgggattgccatgggccacggggggatgctttattcgctgccatctcgcgaactgatc
gctgattccgttgagtatatggtcaacgctcactgcgccgacgccatggtctgcatctct
aactgcgacaaaatcaccccggggatgctgatggcttccctgcgcctgaatattccggtg
atctttgtttccggcggcccgatggaggccgggaaaaccaaactgtccgatcagatcatc
aagctcgatctggttgatgcgatgatccagggcgcagacccgaaagtttctgactcccag
agcgatcaggttgaacgttccgcgtgtccgacctgcggctcctgctccgggatgtttacc
gctaactcaatgaactgcctgaccgaagcgctgggcctgtcgcagccgggcaacggctcg
ctgctggcaactcacgccgatcgtaagcagctgttcctcaatgccggtaaacgcattgtt
gaattgaccaaacgttactacgagcaaaatgacgaaagtgcactgccgcgcaatattgct
agcaaagcggcgtttgaaaacgccatgacgttggatatcgcaatgggcggctctaccaac
accgtacttcacctgctggcggcggcgcaggaagcggaaatcgacttcaccatgagtgat
atcgacaaactttcgcgtaaagtcccgcagttatgtaaagttgcgccgagcacccagaaa
taccatatggaagatgttcaccgtgctggtggtgttatcggtattctcggcgaactggat
cgcgcggggttactgaaccgtgatgtgaaaaacgtacttggcctgacgttgccgcaaacg
ctggaacaatacgacgttatgctgacccaggatgacgcggtaaaaaatatgttccgcgca
ggcccggcaggcattcgtaccacacaggcattctcgcaggattgccgttgggattctctc
gatgacgatcgcgcaaacggctgtatccgctcgctggaacacgcctacagcaaagacggt
ggccttgcggtgctctacggtaatttcgcagaaaacggctgcatcgttaaaaccgcgggc
gtcgatgacagcatcctcaaattcaccggtccggcgaaagtgtacgaaagccaggatgac
gcggtagaagcgattctcggcggcaaagttgtcgctggcgatgtggtggtgatccggtac
gaaggtccgaaaggcggtccggggatgcaggaaatgctctacccaaccagcttcctgaaa
tcaatgggtctcggtaaagtctgcgcgctgatcaccgacggacgcttctccggcggcacc
tctggtctttccatcggccacgtctcgccggaagcggcaagcggcggcagcattggtctg
attgaagacggcgatcttatcgctatcgacattccgaatcgtggcattcagttacaggta
agcgatgccgaactggcggcgcgtcgtgaagcgcaggaagctcgtggcgacaaagcctgg
acgccgaaaaatcgcgaacgtcaggtctcctttgcattgcgcgcctacgccagcctggca
accagcgccgacaaaggtgcggtgcgcgataaatcgaaactggggggttaa
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