KEGG   Esox lucius (northern pike): 105006978
Entry
105006978         CDS       T04894                                 
Symbol
map2k1
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 1
  KO
K04368  mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
Organism
els  Esox lucius (northern pike)
Pathway
els04010  MAPK signaling pathway
els04012  ErbB signaling pathway
els04068  FoxO signaling pathway
els04114  Oocyte meiosis
els04140  Autophagy - animal
els04148  Efferocytosis
els04150  mTOR signaling pathway
els04210  Apoptosis
els04218  Cellular senescence
els04270  Vascular smooth muscle contraction
els04370  VEGF signaling pathway
els04371  Apelin signaling pathway
els04510  Focal adhesion
els04517  IgSF CAM signaling
els04540  Gap junction
els04620  Toll-like receptor signaling pathway
els04810  Regulation of actin cytoskeleton
els04910  Insulin signaling pathway
els04912  GnRH signaling pathway
els04914  Progesterone-mediated oocyte maturation
els04916  Melanogenesis
els05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:els00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105006978 (map2k1)
   04012 ErbB signaling pathway
    105006978 (map2k1)
   04370 VEGF signaling pathway
    105006978 (map2k1)
   04371 Apelin signaling pathway
    105006978 (map2k1)
   04068 FoxO signaling pathway
    105006978 (map2k1)
   04150 mTOR signaling pathway
    105006978 (map2k1)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    105006978 (map2k1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105006978 (map2k1)
   04148 Efferocytosis
    105006978 (map2k1)
  09143 Cell growth and death
   04114 Oocyte meiosis
    105006978 (map2k1)
   04210 Apoptosis
    105006978 (map2k1)
   04218 Cellular senescence
    105006978 (map2k1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105006978 (map2k1)
   04540 Gap junction
    105006978 (map2k1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105006978 (map2k1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    105006978 (map2k1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    105006978 (map2k1)
   04912 GnRH signaling pathway
    105006978 (map2k1)
   04914 Progesterone-mediated oocyte maturation
    105006978 (map2k1)
   04916 Melanogenesis
    105006978 (map2k1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    105006978 (map2k1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105006978 (map2k1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:els01001]
    105006978 (map2k1)
Enzymes [BR:els01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     105006978 (map2k1)
Protein kinases [BR:els01001]
 Serine/threonine kinases: STE group
  STE7 family
   105006978 (map2k1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like Haspin_kinase Seadorna_VP7
Other DBs
NCBI-GeneID: 105006978
NCBI-ProteinID: XP_028970698
LinkDB
Position
LG19:1946231..1967748
AA seq 396 aa
MQKRRKPEPIQLNPIPDGNTINGTGATETNLEALQKKLEELELDEQQRKRLEAFFTQKQK
VGELKDDDMEKICELGAGNGGVVFKVSHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLH
ECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQSLKKAGKIPEQILGKVSIAVIKGLSY
LREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTH
YSVQSDIWSMGLSLVEMAIGRFPIPPPDAHQLELIFGLPVEGGASSSDNTSPKPRPPGRP
GSSYSSDSRPPMAIFELLDYIVNEPPPKLPGIFSLEFQDLVNKRLIKNPTDRADLKQLMV
HQFIKQSEAEEVDFAGWLCSTIGLNQPITPTHSLVM
NT seq 1191 nt   +upstreamnt  +downstreamnt
atgcagaagagaagaaagcccgaaccaattcaactcaacccgatcccggatggaaataca
atcaacggaaccggtgcgacagagaccaacctagaggcccttcagaagaagcttgaagag
ctggaattggacgaacagcagcgtaagcgtctggaggcctttttcactcagaagcagaag
gttggagagctgaaggatgacgacatggagaagatctgtgagctgggtgccggtaatgga
ggggtggtcttcaaggtgtcacacagaccatcaggcctcatcatggcccggaagttgatc
cacctggagatcaagccggccatcaggaaccaaataatcagagagctgcaggtgctgcat
gagtgtaactccccctacatagtgggcttctatggggccttttacagcgatggagagatc
agcatctgtatggaacacatggatgggggctctctggatcagtctctgaagaaagccgga
aagataccagaacagatcctggggaaagtcagcattgcagtaattaaaggactgtcctac
ctgagggagaaacacaagatcatgcatagagatgtaaaaccctctaacatccttgttaac
tcccgtggagagatcaagctgtgtgactttggagtgagtggtcagctcatagactccatg
gccaactcctttgtcggaacccgctcctacatgtctccggagcgtctacagggaacccac
tactcggtccagtcagacatctggagcatggggctgtctctggtggagatggccatcgga
cggttcccgattcctccccctgatgcccaccaactggaactgatctttggcctcccggtg
gaggggggagcctcttcgagtgacaacacctctccaaagccccgacctccgggacggcca
ggcagctcctacagctcagacagcaggcctcccatggctatctttgagctactggactac
atagtcaatgagcctcctcctaagctacctggtattttcagcttggaatttcaagacttg
gtgaacaaacgcttgatcaagaaccccacagacagggcagacctgaagcagttaatggtt
catcagttcatcaagcagtcggaggcagaggaggtggactttgctggctggctgtgtagt
accataggactcaaccagccaatcacccccactcacagtctagtcatgtga

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