Esox lucius (northern pike): 105011646
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Entry
105011646 CDS
T04894
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
els
Esox lucius (northern pike)
Pathway
els04270
Vascular smooth muscle contraction
els04625
C-type lectin receptor signaling pathway
els04810
Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:
els00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
105011646
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
105011646
09153 Circulatory system
04270 Vascular smooth muscle contraction
105011646
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
els04131
]
105011646
Membrane trafficking [BR:
els04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
105011646
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PDZ_2
SOS1_NGEF_PH
Motif
Other DBs
NCBI-GeneID:
105011646
NCBI-ProteinID:
XP_028970194
LinkDB
All DBs
Position
LG01:8515919..8570712
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AA seq
1466 aa
AA seq
DB search
MSDTQSTITDRLPKKANRSSSVLSKDHPPDKKPKSDKPAVPSSHEFDPTDVLVQKSGCVL
AEGKPESCGLVQRCVIIQKDENGFGLTVSGDNPVFVQLVKEDGAAERAGVQTGDRIIKVN
GTLVTHSNHVEVVKLIKSGSYVALTVLGRPPGLPQIPLSEGEAELGFLGGQAGFSVTSPS
SPGQTTGERPYSPLERVTSPLPIWENNSVHSQKVDILQKMLSKEQQDLQAMKDEYSRNPT
PRLLKDIQEAKKHIPQLQGQLSKATGGAQDPLLLGDGDDGSTVDLDHTSSSRGDSSNDLS
WSSSTLSPIFRGFALASPESMCQRDLLSCHSPKSTPRDSLNSCHSPDPEYTLDLESLSPS
TVSSPSSRIVSQIIGAEDDYFDSEQEQVNGQCSCFQSIELLKSRPAHLAAFLHHVVSQFD
PAPLLCYLYADLYKQTNPKETRRVFMDFHTFFIDRGANLKVAVPDSIPSDLDRRRTDLVP
EELNRQYIQMLQDTLLTDIQRNLEDFRQKRSMGLTVAEVELTRLDTERVRDRVALERERS
CAENIIAKIEEVLLTTQPTEEEKCTTMQFVILSYMKHLGVRVKEPRSLESKRVRINFLPK
IKKSIKTEKEGGEEKVKRTRFPSILGPQRRPSRVDPTSVGKAVDLNKPRPQKQLSQPCLG
ALEHLEAGRLRASQSSEGSELTHSSSINASLVPNSAANSHTSDGGSRDSECGGTPNSALS
RLNEVAGDLDSLPCSPNMQFDYSLDQLQEEDRESGILDGTPKAIRRLDALGSVEVQSEDD
QGGTDSEHDPLNWQQLVGREVLAGLRPHEIKRQEVINELFYTERAHLRMLKVLDNIFYQK
LTREAILPPADIKNIFTNLEDIVQLHVSISEQMAAIRKRNESSVIDQIGDDLLSWFSGGE
EEKIKQAVGTFCSNQPFALELIKSRQKKDSRFTSFMQEAESNRLCRRLQLKDIIPVEMQR
LTKYPLLLESIVKYTDDLAEKDKVKKAGDCCRRILNHVNQAVKESENKQRLEDYQRRLDL
SSLKQTENPMISELKNLDLTKKKMVHEGPLSWKVNKDKTIELYTLLLEDILVLLQKQDER
LILKCHSKNLSGTADTKHIFSPIIKLNTVLVRSVATDNKSFFVLSMSENGAQIYELMAQT
VSEQRMWQRHITQRADAMKVKPHSVIPLPQTDGERDGVETITERVGRLGKDPERVSSGSN
LSTDKDGSPASSGVLHTSLDSAGRFEGLKPEVEEEEASRDNGLYGEPVFVERLPFPVTVD
GFVESDALGFGPSRADDALKTLSALKQVLVTQLMSQEDSERAGRASSGGGRLLRTTSLRT
PVDSRARVAVQNGSGRTGHACHPEDPSQDLASGDTGFFESSEDYAGYLVLEGYGGSRESS
TDDDLQGKQLSASRGCGAGDSGISLRFSSTSQAGSVSGFSPQVLSYLRNLQTNLNHLKEV
EAKYYSLLRQRPARSSTDTDDNKDKR
NT seq
4401 nt
NT seq
+upstream
nt +downstream
nt
atgagcgacacacagtccactatcactgacaggttacccaagaaagcaaacagaagcagc
agcgttctcagtaaagaccatccccctgacaagaaacccaaaagcgataaaccggcagtc
ccctcttcacatgagtttgaccctacagacgttttggtgcagaagagtggctgtgttctg
gctgaggggaagcctgaatcctgtgggcttgtccagcgatgtgtgattattcagaaagat
gagaatggctttgggctgacagtgagtggcgacaaccctgtttttgtgcagcttgttaaa
gaagatggcgctgccgagcgtgcaggtgtacagacgggtgacaggataatcaaggtgaac
gggacgctagtaacgcattcgaaccatgtggaagtagtaaagctcatcaaatctggctcc
tatgtggccctcacggtgttgggaagacccccagggttaccccagatccctttgtcggag
ggcgaggctgagctggggttcctggggggccaggcagggttctccgtcacctcccccagt
tcccctggacagacgacgggggagcgcccctacagccccctggagcgcgtcacgtctcct
ctgccaatatgggagaacaacagcgtacacagccaaaaggttgacatcctgcagaagatg
ctgtccaaggagcaacaagatttgcaggcaatgaaggatgagtacagcaggaacccgacg
cccagactgctgaaggacatccaggaagccaagaagcacattccacagctgcagggccag
ctcagcaaggccactgggggtgcccaggaccccctgctgttgggcgacggagacgacggc
agcacggtggacctggaccacacatcgtcctccaggggggacagtagcaacgacctgtcg
tggagcagcagcactctgtcccctattttccgcggttttgccctcgcctccccggagagc
atgtgccagagggacttgttgtcgtgccacagcccaaagagcacgcctcgagacagcttg
aactcctgccactcccctgacccggaatatactctagacctggagtccctgtccccctcc
actgtcagcagcccctcctcgcgcatcgtctcccagatcatcggagccgaggacgattat
tttgactctgagcaggagcaggtcaacggccagtgcagctgtttccaaagcatagagctg
ctcaagtccagacctgcccacctggcggcgttcctgcatcacgtcgtctcccagtttgat
cccgcgccgctgctgtgctacctctacgctgacctgtacaagcagaccaaccctaaagag
accaggcgggtgttcatggatttccacacgttcttcatcgaccggggcgctaatttaaaa
gtagctgttcccgattctatcccttctgaccttgaccggcggaggacagacctggtcccc
gaggagctcaatcgccagtatatccagatgctacaggacaccctgctcactgacattcag
aggaatctggaggacttcaggcagaagcgcagtatgggtttgaccgtggcagaggtggaa
ctgacccggctggacacagagcgtgtcagagaccgggtagccttggagagagaacgctcc
tgtgctgaaaacataattgccaagattgaggaagtcttattgacaactcagcctacagag
gaagagaaatgcactactatgcagttcgtcatcctcagctacatgaagcacctcggagtc
agggtcaaagagccacgcagcctggagtcgaaacgggtccgcatcaactttctccccaag
atcaagaagagcatcaagaccgagaaggagggtggcgaggagaaggtgaaacggaccaga
tttcccagcatccttgggcctcaacgccggcccagccgagtggaccccacatctgttggc
aaggcggtggacctcaacaagccgcggccccaaaagcagctctcccagccctgcctgggg
gccctggagcacctggaggcggggcggctgagggccagtcagtccagcgagggctctgag
ctcacacattcctcctcaatcaacgccagtttggtccccaacagtgccgccaacagtcac
acctccgacggaggcagtagagattcagagtgtggtggaacccccaactctgccctctcc
cggctgaacgaggtggccggagacctggatagtctgccctgctctcctaacatgcagttt
gactacagcctggaccagctgcaggaggaggaccgggagagcggaattcttgatggaaca
ccaaaggcgatcagaaggttggatgcccttggctccgtggaggtgcagagtgaagatgac
cagggaggtaccgactctgagcacgaccccctcaactggcagcagctggtgggacgagag
gtcctggccgggctgaggccccacgagatcaagaggcaggaagtcatcaatgagctgttc
tacactgagagagcccacctgcggatgctcaaagtgctggacaacattttctaccagaag
ctcaccagagaggccatactgccgcctgctgacatcaagaacatcttcaccaacctagag
gacatcgttcaactacatgtttcgatatcggagcaaatggcagcaattcggaaaaggaat
gagtcatccgtaatcgaccaaataggagacgacttgctttcttggttcagtggcggcgag
gaggagaaaatcaagcaggctgtgggcactttctgcagcaaccagccctttgctctggag
cttatcaagagccgacagaagaaggactcgcgcttcacctcctttatgcaggaagctgag
agtaacagactgtgtcgaagactccagctaaaggacatcattcctgtggagatgcagagg
ctcaccaagtatccactgctactggagagcattgtcaaatacactgacgacttggcagag
aaggacaaggtaaagaaggcaggcgactgctgcaggaggatcctcaaccatgttaaccaa
gctgtgaaggagtctgaaaacaaacagaggctggaggactaccagcgacgtttagacctc
tcgtctctgaagcagacagagaaccccatgatttcagagctcaagaacctggacctgacc
aagaagaagatggtccatgaaggaccactgtcatggaaggtcaacaaggataagaccatt
gagctgtacacgctgctcctggaggacatcctggtgctgctgcagaagcaggacgagcgt
ctcatccttaagtgccacagtaagaacctgtcgggcaccgcggacaccaagcacatcttc
agccccatcatcaagctcaacactgtgctggtgcgctccgtagccactgacaacaagtcg
ttctttgtgctctccatgtcggaaaacggtgcccagatctacgagctgatggcccagacg
gtgtcagagcaaagaatgtggcagcgccatatcacccagagagcggacgccatgaaagta
aagccgcacagcgtcatccccttaccccagactgatggcgagagggacggcgtggagacc
atcaccgaacgcgtaggccgacttggcaaggacccggaacgcgtctccagcggaagcaac
ctgtcaacagataaagatggtagccccgcctccagcggtgtgttgcacacgtctctggac
agcgccggccgcttcgaaggactcaagcccgaggtggaagaggaggaggccagcagggac
aacgggctttacggggagccggtcttcgtggaaaggctacccttcccggtgaccgtagac
gggtttgtcgaatcggacgccctgggcttcggtccttccagagccgacgacgccttgaag
acgttgtcggcgctcaagcaggtcctggtgacccagttgatgtcgcaggaggacagcgaa
cgagccgggcgcgcctcctcgggcggcgggcgcctcctccggaccacgtccctgagaacc
cccgtggacagtcgggcccgggtggcggtgcagaacggctccggtaggacgggccacgcc
tgccacccggaagacccgtcacaggacctggcgtctggggacacgggcttcttcgagtct
tctgaggattacgcaggttacctggttctggagggctacgggggctcaagggaaagcagc
acggacgatgacctccaggggaagcagctgagcgcctcgcgggggtgtggggcaggggac
tctgggatcagcctgaggttctcctccacctcgcaggcaggcagcgtctcaggcttcagc
ccgcaggtcttgtcctacctccgtaatctgcagaccaacctcaaccacctcaaggaggtg
gaggccaagtattacagcctactacgccaaaggccagccaggtcctccacagacacggac
gataacaaagataagagatag
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