Esox lucius (northern pike): 105014388
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Entry
105014388 CDS
T04894
Symbol
araf
Name
(RefSeq) serine/threonine-protein kinase A-Raf
KO
K08845
A-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
els
Esox lucius (northern pike)
Pathway
els04010
MAPK signaling pathway
els04012
ErbB signaling pathway
els04068
FoxO signaling pathway
els04270
Vascular smooth muscle contraction
els04810
Regulation of actin cytoskeleton
els04910
Insulin signaling pathway
els04914
Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:
els00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105014388 (araf)
04012 ErbB signaling pathway
105014388 (araf)
04068 FoxO signaling pathway
105014388 (araf)
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
105014388 (araf)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
105014388 (araf)
04914 Progesterone-mediated oocyte maturation
105014388 (araf)
09153 Circulatory system
04270 Vascular smooth muscle contraction
105014388 (araf)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
els01001
]
105014388 (araf)
Enzymes [BR:
els01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
105014388 (araf)
Protein kinases [BR:
els01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
105014388 (araf)
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Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
Pkinase_fungal
Kdo
TUG-UBL1
C1_2
Motif
Other DBs
NCBI-GeneID:
105014388
NCBI-ProteinID:
XP_010874967
UniProt:
A0AAY5KI24
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Position
LG13:13876652..13887145
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AA seq
610 aa
AA seq
DB search
MSSNSSSCSSSGETSPEDVPRGGGTIRVFLPNKQRTVVNVRPGQTVYDSLDKALKVRGLS
QDCCAVFRLLEGRKRLTDWNTDITPLVGEELLVEVLDDVPLTMHNFVRKTFFKLAYCDFC
HKFLFNGFRCQTCGYKFHQHCSSKVPTVCVDMDTMTKRFTPNPCTDEYPQISILPDNSIS
ESDLALTPDPSGHGLLSPTSAFRFPLPGGDGQSLQRHRSTSTPNVHMVSTVGPAGVSIIE
EALKIQNNTMGPEPSPKPSTSPPSLGSPGRRPPKSPSEHKERKPSSSDDKKKVHRGGYRD
SSYYWEVHSREVTIQKRIGAGSFGTVFKGKWHGDVAIKILKVTEPTPEQLQAFKNEMQVL
RKTRHVNILLFMGFMTKPNFAIITQWCEGSSLYRHLHVSETKFDTMRRIDVARQTAQGMD
YLHAKNIIHRDLKSNNIFLHEGWTVKIGDFGLATVKSRWSGSQQVEQPSGSILWMAPEVI
RMQDANPYTFQSDVYGYGVVLFELMSGTLPYSQINNRDQILFMVGRGYLSPDLSLLSSSS
PKSMKRLIIDCLKFKRDERPLFPQIMLGIEQVQDLLPKIERSASEPSLHRAVHAEELNPL
LFHTTRLMPL
NT seq
1833 nt
NT seq
+upstream
nt +downstream
nt
atgtcctcaaactcctcctcctgctcctcctcgggagagaccagtccagaggacgtgccc
cgaggtgggggcaccatccgcgtcttccttccaaataaacagaggaccgtggtaaatgtt
cgccctgggcagacggtttatgacagtttggacaaagcccttaaagtaaggggcctgagc
caggactgttgtgctgtgtttcgacttttagagggtcgcaagagactaactgactggaac
actgacatcacccccctggtgggagaagaactgctggtagaggtgttggatgatgtccct
ctcactatgcataactttgtacggaaaaccttcttcaagttggcctactgtgacttctgc
cacaagtttctgttcaacggcttcagatgtcaaacatgtggctacaagtttcaccagcac
tgcagcagcaaagtccccactgtgtgcgtggacatggacactatgacgaaacggttcacg
ccgaatccctgcacagatgagtaccctcagatatccatactgccagacaactctatatcc
gagagtgacttagccttaaccccagatccttctgggcatggactactgtccccgacctcg
gccttccgcttcccacttccaggtggtgatggtcagtctctacagaggcaccggtcaacc
tccacccccaacgtccacatggtcagcaccgtgggccctgccggcgtcagcatcatcgag
gaggcgttaaaaatacaaaacaacacaatgggtcccgaaccatcacccaaaccctctacc
agcccgccctccctgggctcccctggccggagacctccgaaatccccctcagagcacaag
gagcgcaagccctcgtcgtctgacgacaagaagaaagtgcaccgtggcggttatagagat
tcaagttactactgggaagtccactcacgagaggtcaccatccagaagagaataggcgca
ggctccttcgggactgtcttcaagggcaagtggcacggagatgtggccattaagatcctt
aaagtgaccgagccgacgcctgagcagttacaagcctttaaaaatgaaatgcaggtctta
cgaaagacacgccacgtcaacatcctgctgttcatgggcttcatgactaagcccaacttt
gccatcatcacacagtggtgtgaaggtagcagcctgtaccgccatctgcatgtctctgag
accaagtttgacaccatgcgacgcattgacgtggccaggcagacggcacagggcatggat
tatcttcatgccaaaaatataattcatcgagacctgaaatcaaacaatatcttcctccat
gaaggctggactgtgaagataggggatttcgggctggccactgtgaagtctcgctggagt
ggctctcagcaggttgaacagcccagcggctccattctctggatggctccagaggtgatc
cgtatgcaggacgccaacccatatacgttccagtcagatgtttatggttacggggtggtg
ctgtttgagctcatgtcagggactctgccttattcccaaatcaacaaccgagaccagata
ctctttatggttgggcgtggctacttgtctccagacctcagtttgctgtccagtagctcc
cccaagtcaatgaagaggcttatcattgactgcctgaagttcaagcgtgacgagaggccc
ctttttccacagatcatgttaggcattgagcaggtccaggacctgttgccaaaaatagag
cggagtgcctccgagccctccctccaccgggctgtccacgcagaggaactgaacccactg
ttgttccacaccactcggctgatgcccctgtga
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