Esox lucius (northern pike): 105019025 Help Entry 105019025         CDS       T04894                                  Symbol sacs Name (RefSeq) sacsin isoform X2   KO K17592   sacsin Organism els  Esox lucius (northern pike) Brite KEGG Orthology (KO) [BR:els00001]  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:els01009]     105019025 (sacs) Protein phosphatases and associated proteins [BR:els01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      105019025 (sacs) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  HEPN ubiquitin DnaJ Motif Other DBs NCBI-GeneID:  105019025 NCBI-ProteinID:  XP_010883246 LinkDB All DBs Position LG01:23312767..23368587 Genome browser AA seq 4585 aa AA seqDB search MANCRDPWLPWVTVRHEYIGHRAYQVPYSVAVWDIKQLIFEETDFPVTEQQLVHNGRVLD DRVQIGTLVPTGSPEIRITLEAKGLKGGGRFGQTTPPLVEFLKDILRRYPEGGQILKELI QNAEDAGATEVRFMYDETEYGVESLWSPDMAQYQGAALYVYNDAVFTTEDWNGIQEIARS RKREDPLKVGRFGIGFNSVYHITDVPSIFSGEQIGMLDPHQTLFGTNETGQCWNLKTDMK EITELIDQFAPYIGLFGSTGKTIKDGSFSGTLFRFPLRIRPSQLSYNIYNKEKVLELFES FKADADTVLLFLKSVQKVSLHLRESDGTERMLFQVTAGENPDDKLERPNSLKTLGQATDS YNNGVPSSTVTCATYQVNIETQDETTKETQRTTWLVCNGVGGRGLCSDLDSLADDLKFIP TIGIALPLTLIDEGKEATSGFSGRAFCFLPLPPGEESLTGLPVHVSGFFGLTDNRRSIKW REVDQWRDPAALWNELLIVTVIPRAYFTLIMEAIKRIQNKTDQDFTLSPRGTYGAWPDPN RIKPRWKPILEPLFHDLLQQKVINTLTNSWIQVDEAVFSELDTDADTTETVISYLQSSGM QVARVPATVDVVLNSYMTGPACVNKVNPSLVRQVIRKAKHKVSSQEKLLLLEFVLSDRGY SELIGLELLPLQDETFAAFSSSVNDKDAIYIPSEEFPRSLYPGLEGRFIMEGIKPSIMSS LKDAAKSRGRPCTQVQMLTPERSARLIKEILSKAWPTREFTVQWDPGNREKKHPTLSWLK MIWKHLYINFADDLSTFEDMPLIPNVPLEESAGLIELHRLKTPSPIIIADEDTPLSESLL EIMKKLGVVMMKKLDLCLQHPLLKNYIHPSSPSMLLQIMDKSSTQRVASLVSSFSSKQKV ALRDFLAGLSDITEKEKRILLELTIFEKIGPLSEKSIPTYTSLRGARALHHTAKYPPDVR LSINLVGCSDEASIRLIKMLNVEQVKTTDCLKLVIQDIERGFYSKEEITKIMLWVLKHMS FLKNENKSVIGWLSSLKFIYTSAGKSVAATDLFDPELEILQTLFYMEKNRFPTSTYTASP DILHSLRQLGLKNEVQLIEKDVLQVARKIEELQGGNEPEWEPIIQKAKTLLQILNRQTKL VKSSEAQISLQKLKWVPVCKDRPVNYPKSLAWMGDTHNICSFSEMCDISHAVLVGSSVAL VERTSAGMKKALKLSTEPLIDQVLQHLKAVNDWHRSQAFTTEDWYQFQQILIEIYDFMQA HLEDAREAMKSLPFDWVWTGKTFSSPCHTVLKPIPDLDLQPYLYSLPKTIAKFHRLFKFC GSVEEVIPNHVFDVIKTIRKRCDEKMTKEESKHDLLLMINILRWLYNSQISVDIDMHVPI LCYKDPNKLAMKPIHECTYCDIKVEDLHDLLDDTSEPIILIHDDIPMKTAEWLNVPCLST RLINPENLGFEQSGQREPLTVRIKNILEEYPSVADIFKELLQNADDASATECSFLIDMRK NIEIRENLLDPGMIICHGPSLWSFNNSTFSDTDFLNITRLGGSMKRCEADKVGKFGLGFN SVYHITDIPIIMSREFMIMFDPNINHISKHIRDRSNPGIKINWSKQQKRLRKFPNQFKPF INVFNCQLPLAQECPYKYDGTLFRLPFRTEQEASVSEISSIYYNTTDIYSLVDEFSMCGH RLILFTQHVGSMVLKYLKYEEPNPAAAQDVVTINKSVWSSKAAYGPLSILKSAAKVMKKV AATNRVPADTPKSGCIIRIVVEEFHNVFKRIVDLQSPLFRGSEEDPSSYFEMAAKDGKNR RLTDEMPQKAVELTNWLICSCMDVTEALKFSLGESGKRLGLVPCGGVAVLLSEEENRKWT VKANTNHTNPIGEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIWKTDTKGHWNSVFMRNV IVQAYLAALSMLRSMAESGELLDYSYYVAWPDPSVVHNDFTVISQGVYQEIAKGGDCEHA KVFSDGKIWVSIKYVRFLDDSLLCRPDIGPAAFQIFLKYLKKSGSQDLCAVELPDWVKEG FEDAGCKGKLMENTLTEKQFFSDVFFPHIHDIDKELRDPLMHYVLNDKLDEFASILKETP CIPCSAQNQQLVLPSRLIHPEGRVAKLYNTDDGRFPEGTSKDYMNPVCLVKLVQLGMVKD DLSWEDLIERAESVFDLNENDHTAACLRSSIILSLIDEKLKMTDSGAGQLLEKLQDIKFL PFLTKPAGFSLPWHGNTFPPSTMFSAKELFTTDHQDTVCLMKPILNENSPSFKGCGTITL AVKDYLGLLRKPTVGLVVSQLKELAKSFDGVTLYQENITNACYKYLHEEMLQDAKAKTQI NEELKTFCSILVENTYVEPFKVAFYQNFDAAPYLYQLPNKYRNSCRELFENVGVQSSFTV ENFSAVLELVKQECGRKALSEDKFQLCRRIISEGIWSLIREKTQEFCQAAYREILLPDTH LTLQPSKSLCYNDCPWIKVRDTTVKYCHSDIPREVAVKLGAIPKRHKALERYASNVCFTT LGSEFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEIYFVFDPRTHPTDRIFD DKWLPMQGPSLCVYNNQPFTEDDVRGIQNLGRGTKEANPGKTGQYGIGFNSVYHITDCPS FLSNNDILCIFDPHARYAPGSTSISPGRMFRDLDSDFRSQFSDVLNLYLGTHFKLEHSTM FRFPIRSTEMAKISEISSVAASDRMVQNLLDKLKNDGAELLMFLNHMEKISICEIEKPTG DLKVLYSVTAKITDGDRLKRKQFHASVVDSVTKKKQLTQIPVQQITYSMDIENTDGNLTT WMVCNRSGFSCIEKVSKSVISAHKNEDITLFPRGGVAACVSHNYKKPHRAFCFLPLSLET GLPFHVNGHFALDSARRNLWRDDNGVGVRSDWNNNLMTFLIAPAYVELMTQMKRRYFPGP DPTMTVLQGTPIHIVKDTLRKFLFFFPVNRLDIQPDWYCLVKAVYTCIHADQKRLLPVVR APQIDNTDLHSAVYISWVNTSSSSNKGKAFFDNLLQDELQHLKNTEYNISSRKSVAENVF RLKALLLDVGFNLVHSCDETASLYFCLDDAGIPVSYVTPRDVRNFLLTFSSQDTSCQVGK LPCRLQQSNYKLFHSLKLLVDYCFKDVEEDEIDIVGLPLLITMDNILQVFDTKRPRFLTT HHELISSRKELFMNTLYMRYNNILMKAGVAKIFDISSFGELLSSVLPREYRTRIPVKWRD NYASESWLKGAWHFISENIAVKEEQAGAKPNFETVLDILKDWALLPGIKYMVSSTKLVVP DHDMLLPLGLISTAIFPNGQNDKVFHTLMKGGCIQVAVNKICVKENPVLTLMAQHTANID NPSSILRALEYMIQTSTFKTGSLTDKDFEALLLYFNCNLINLTEEDAQTLKLLPCFKSVS GRYMSIANIGSCYVLAKSIPSADMEKWAHTTHFAFLADNPQLKELYSFLRCSLIDDLEVY LKHLLPKFDSLSYDAKIDHLVYLKDRLMDIEESCGIKDQLYEKLEGLSIIYDYTNRLKST KMFYDQTVKVFEMMLPPKAFIPNDFFKKIEQVSKPKNGTAFHTSWITFLRNIGLRHIVSQ QQILQYAKEVSIKAQTESWSKEKTQMIVDVLLNHIFNERTDLFVGSFLKELSMIPFLCPE RAPTELIRLHAQFQEMNGTLPLIRFSGSQVNPKFKQTDIIQLLWTSCPILPEKATPAAIK DQEGSTLTGQEQLDLVLTMLSVNLEPPLDKVISNCKNICNISNPDDDMVKTRNKVLRSTY EFLNADKRDFRFQLRGVSFVMVEEGWKLLKPEEVVINLDNESDFKPYLYKLPLPLGTFHQ LFKLLGTEDVVSTKQYVEVMCRIHRNSEGKQLDPNEMRTVKRAVSGLFKSLQNDPVQIRK DLESLRDLIFYLPSHDGRLAKSNSLVFDDAPHYKSRIQGNVGVQMLVDMSQCYLGKDHSF HTKLIMLLPPKLRPRLLSSILEEQLDEESPKMCQFGALCSLQGRLQLLLSSEQFITGLIR IMKHENDNAFLVNEEKAIRLCKALCEGLKVSCFEKLQTTLRVKGCSPIPLSRSETLAFLK RYGTAVIHLYIQHSDSKDINFLLALAMTLKSATDNLISDTSYLIAMLGCNDIYRITEKLD NLGVKYDSTEPSKLELPLPGTPIPAEIHHILLMDPMNVFYPGEYVGYLVDSEGGDFYGGY QPTYTYAIIVQEVEKEEDDNPSFLGKCFQIDIGYSEYKIVSSLDLYKFSRQEESSHIRDS SAPSTPTSPSECHSPGPGPRLVPPHFTGKENHKVPPTKQSPKKIRLSALPDILKEVSLVI EQAWKLSEMERKKIIRRLYLKWHPDKNAENLDIATEVFKHLQNEINRMEKHTLTDQHNTD RASRRTFSTSSTRFQSEKFSFQRFYTSWNQEATSHKSEKQQFREQFTTYAGSSHSNRFFV PPTFKSVGNPVEARRWLRQARANFSAARNDLHKNANEWVCFKCYLATKLALIAADYSVRG KSDKDVKPTALAQKVEEYNPQLAGLAKDVNILEGYGVDSLRTRYPDLLPFPQIPNDRYTS EVAMRVMECTARIIIKLETFVQQKI NT seq 13758 nt NT seq  +upstreamnt  +downstreamnt atggcaaactgtcgagacccatggttgccttgggtgacagtccgtcatgagtatattggc cacagagcctaccaggtcccttattctgttgctgtctgggacataaagcaacttatcttt gaagaaacagactttcctgtcacggagcagcagctggttcacaatgggagagtgctggat gacagagtgcagattgggacgcttgtgcccacaggaagccctgaaatacgcataacactg gaagcaaagggcctgaaagggggagggcggtttggacagacgacaccaccattggttgag tttttgaaagatattctaagaagatatcctgaaggtggacagattctaaaagagctgata cagaatgctgaggatgctggagccacggaggtcaggtttatgtacgatgagacagagtat ggagtggagtcactttggtcacctgacatggctcagtatcaaggagctgccttgtatgtg tacaatgatgcagtgttcacaactgaagattggaatgggattcaggagatagcaaggagc agaaagagagaggatccattgaaagttggacggttcggtattgggttcaattctgtgtac cacataacagatgtgcccagcatattcagtggagaacaaattggaatgctggaccctcac cagacactgtttgggaccaatgagactggtcagtgttggaacttgaagacagacatgaag gagatcacagagctcattgaccagtttgcaccctacataggcttatttgggagtacagga aaaaccattaaggatggcagcttctctggaaccctcttccgctttcccctccgcattaga ccctcccagctgagttacaacatctataacaaagagaaggtcctggagctctttgagtct ttcaaagctgatgctgacacagtgctcctcttcctcaagagtgttcaaaaggtctctctg catctgcgtgaatcagatggtacagaacgtatgctctttcaggttacggctggagagaac ccagacgacaagctggagcggcccaactcattgaagaccctgggccaggccacagacagc tacaacaatggagtgcccagcagtactgttacttgcgcaacctaccaggtcaacattgaa acccaggacgagacaaccaaggagacccaaaggaccacatggctagtctgtaacggtgtg gggggcagaggattgtgcagtgatttggactccctggcagatgatctgaagttcattcca accatcggcattgccttgcctcttactctcattgacgagggaaaggaagccacatctggt ttctctggtcgagccttctgtttcctgcctcttccccctggggaagaaagcttgactgga ctgccagtccacgtcagtggcttttttggcctaacagacaaccgcagaagcatcaaatgg cgggaggtggaccagtggagggaccctgcagctctctggaacgagctcctcatcgtgaca gtcatccccagggcctacttcacccttatcatggaggccatcaagaggatccaaaacaag acagaccaagacttcacactctctcccagaggcacctacggggcctggcctgaccccaac cggatcaagcctcgctggaagcctatactggagcctctctttcatgacttgttacagcaa aaggtcatcaacactcttactaacagctggatccaggtggacgaggctgtgttttcagag ctggacacagatgcagacaccacagagactgtgatcagctaccttcaaagctcagggatg caggtggctagagtgcctgccactgtggatgtagtcctgaactcttacatgactgggcct gcatgtgtgaacaaggtgaacccttccctggtgcgccaggtcatcaggaaggccaaacac aaagtttcctctcaggaaaagctgcttctgctcgagtttgtccttagtgacaggggttac agtgaactcattggactggagctgctgcctttgcaagatgagacatttgcagcattctcc tcctctgtcaatgataaggatgctatttacatcccttctgaagagttccccaggtctctc taccctggactggagggaagattcataatggagggcattaagccgtccattatgagcagc ctgaaggacgctgccaaaagcagaggaagaccctgcactcaggttcaaatgttaacacca gaacggtctgctcgactcataaaagagatcctctcaaaagcctggcctaccagagaattc acagtccaatgggaccctgggaaccgagagaaaaagcatcctacactgtcttggttgaag atgatttggaagcatctttatattaactttgctgatgaccttagtacctttgaagatatg cctttgatcccaaatgtgccactggaggaaagtgcaggcttaatcgagctccatcgtctt aaaactccatcccctattatcattgcagatgaggacaccccactttccgaaagccttctt gaaatcatgaaaaaacttggagtagtaatgatgaaaaagttggatctttgtttgcagcac cctctactgaagaactacattcatccttcatcacccagtatgctattgcaaatcatggac aagtcgtcaacccagagagtggccagcctggtctcatccttctctagcaaacaaaaagtt gcactgagagacttcctggcagggctgtctgacattacagaaaaagagaagcgtatcctg ttggagcttaccatctttgagaaaatagggccactttcagaaaaaagcatcccaacatat acctctctgagaggagcaagggcattacaccatacagccaagtatccaccagatgtcagg ctatctattaaccttgtgggctgtagtgatgaggcatcaattcgtctcattaagatgctg aacgtggagcaggtgaaaactactgactgtttgaaattggtcattcaagatatagagaga ggattttactcaaaagaagagatcacaaaaattatgctttgggtccttaagcatatgtca ttcctaaagaatgaaaacaaatctgtgattggatggctttcttctctgaaattcatttat acatctgcaggaaaatctgttgcggctaccgacctttttgaccctgagctggagattttg cagactctgttctatatggagaagaataggtttcccacaagtacatatacggcatctcct gatatccttcattcactgagacaacttggactgaaaaatgaagtccaactcattgaaaag gatgtacttcaggtggcacgaaagatagaggaattacagggtggcaatgagccagaatgg gaaccaattatacagaaagcgaaaacactgctgcaaatactcaacagacaaaccaagctg gtaaagtcttcggaagctcagatatccttgcaaaaactgaaatgggttccagtctgcaag gacagacctgtaaattacccaaagtcccttgcctggatgggagacacccataacatttgt tcattctcagaaatgtgtgatatatcccatgcagttcttgtaggatcttcagttgcactt gttgaacgcacttcagctggtatgaagaaggccctgaagttatccacagagccactgatt gatcaagtgttacagcacttaaaggctgtgaatgactggcacagatcgcaagcatttacc acagaagactggtatcaattccaacaaatccttattgagatttatgacttcatgcaagca caccttgaagatgcaagagaggcaatgaagtcattgccatttgattgggtgtggactggc aagacattttcatcaccctgccacacagttctaaaacccattcctgaccttgatttgcag ccctacctgtactctttgccaaagaccattgcaaagtttcacagactttttaaattctgt ggttcagttgaagaggttatcccaaaccatgtttttgatgtgatcaaaacaataagaaaa aggtgtgatgaaaaaatgactaaagaggaaagtaagcatgatcttcttcttatgataaat attttacgatggctgtataacagtcaaatttctgtggacattgacatgcatgtaccaatc ctttgctacaaggacccaaacaaacttgccatgaaaccaattcatgaatgcacctactgt gacattaaagtagaggatctacatgacttacttgatgacacgtctgagcccattatctta atccatgatgacatccccatgaaaacagcagaatggctgaatgtgccatgtttgagtacc aggctgataaacccagaaaaccttggctttgaacaatcaggccaacgggaacctctgaca gtgagaataaaaaatattttagaagaatatccatctgttgcagatattttcaaagaactt cttcagaatgctgatgatgctagtgctacagagtgtagcttcctgatagacatgcgaaag aatattgaaattcgagagaacttgcttgaccctggaatgattatatgccatggcccgtct ttgtggtcattcaacaattctacattctctgacactgattttctgaacataacaagatta ggtgggtcaatgaagagatgtgaagcagacaaagttggcaaatttggccttggattcaac tctgtttaccacatcactgacatcccaatcataatgagcagagaattcatgatcatgttt gatccaaacatcaaccacatcagcaagcatattagagaccggtcaaacccgggaatcaag atcaactggagcaaacaacagaaacgcctgcgaaagttccccaatcaattcaaacccttc atcaatgtcttcaactgccaacttcctcttgcccaagagtgtccatacaagtatgatgga acgctgttcagacttcccttccgaacagagcaagaagcatccgtaagtgaaatcagcagc atctactacaacaccacagatatctactcccttgttgatgagttcagcatgtgtggccac aggctaatcctcttcacacagcatgtcggctcaatggtactgaagtacttgaaatatgaa gagcccaatccagcagcagcacaggatgttgttactatcaacaaaagtgtttggtcatcc aaagctgcatatggaccgctaagcatcctgaaatctgcagcaaaagtaatgaaaaaggta gctgccaccaacagggtaccggctgacactcccaagtctggctgcattatacgcattgtg gtggaggagtttcacaatgtgtttaagcgcatagttgatctccagtcccccctcttcaga ggttcagaagaggatccgtcatcatactttgaaatggctgccaaagatggaaaaaacaga cgactcacagatgaaatgccacaaaaagctgttgagttaacaaactggctcatttgttca tgtatggatgtgactgaagcacttaaattttcccttggtgagagcggaaaacgacttgga ctagtcccttgtgggggtgtagctgttctgctttcagaagaggagaatcgaaaatggaca gtaaaggcaaataccaaccacaccaatccaataggagaagtgttttgctatttgcctctc agaatcaaaacaggcttgccagtccatataaatggttgttttgctgtgacatctaaccgt aaagaaatctggaagacagacaccaaaggacactggaattcagtgttcatgagaaatgtg attgttcaggcatacttagcagcactcagtatgctccgttcaatggcagaaagtggagaa ctgcttgactatagctactacgtagcatggcctgatccaagtgtagtacacaatgacttc acagtgatcagccaaggagtctatcaagaaattgcgaaaggcggtgactgtgaacatgca aaagttttttctgatggcaaaatctgggtatcaatcaaatatgtccgattcctagacgac tccctgctctgcagaccagacattggtcctgcagccttccagatatttttgaagtacctc aaaaaaagcggctcccaagacctatgtgcggttgagctgcctgactgggtcaaggaaggt ttcgaagatgctggatgcaaaggaaagctaatggagaacactctgacagaaaagcagttt ttctcagatgtttttttccctcatatccatgacattgacaaagaactccgtgatccccta atgcattatgtcttaaatgacaaactggacgaatttgcatcaatacttaaagagactcca tgtatcccatgctctgcccagaatcagcaattagtgttaccatccagactaatccaccca gaaggaagagtggccaaactatacaacactgatgatggaagatttccagaaggaacctca aaagactacatgaatccagtatgcttggtcaagctagtacagctggggatggttaaggat gacctttcttgggaggatttgattgaacgtgctgaatctgtgtttgatctaaatgaaaat gatcataccgctgcatgtcttcggagcagcattattctgagtctcattgatgagaagctt aaaatgacagattcaggagcgggtcaactgctggaaaagttacaagacataaagtttctt ccatttctgacaaagcctgcaggattttcactaccatggcatgggaatactttcccccca tccacaatgttttcagccaaagagctctttacaacagaccaccaggacacagtgtgcttg atgaaacctatcctaaatgagaattctccatcattcaaagggtgtggcacaataactttg gctgttaaagattatcttggattgctaagaaagccaacagttggattagttgtcagtcaa cttaaggaacttgccaagtcatttgatggagttactctgtatcaagaaaatatcaccaac gcctgctacaaatatcttcatgaagaaatgctccaggatgccaaggcaaagacacagatc aatgaggagctgaaaaccttctgctccattcttgtggagaacacttacgttgagcctttc aaagttgcattctaccagaactttgatgcagcaccatatctctaccagcttcccaacaag tacagaaacagttgccgtgagctatttgaaaatgttggggttcagtcgagcttcactgtt gagaacttttcagcagtacttgaattagtgaaacaggaatgtggcagaaaagcactctct gaagataaatttcagctctgtcgtagaatcattagtgaaggaatatggagtttaatcaga gagaagacacaggaattctgccaagctgcctacagggaaattcttcttcctgatacccat cttacactccagccttcaaagtctctgtgttacaatgactgcccatggatcaaagtcaga gatacaactgtgaaatattgtcattcagatattccaagagaggttgctgtgaaacttggt gcaattcccaaacgtcacaaagccttggaaaggtatgcatcaaatgtctgcttcactacg cttggtagtgagtttggacaaaaagagaaactcacaagtagaattaaaagtattctcaat gcttacccatcagaaaaagaaatgctgaaggagctcctgcagaatgcagatgatgctaaa gccacagaaatctattttgtttttgatccaagaacccaccctacagacagaatatttgat gacaaatggttgccaatgcaaggcccatccctttgtgtctacaacaatcagcccttcact gaggatgatgtcagaggaatccagaacctaggaagaggaacaaaagaagcaaacccaggc aaaactggacaatatggcataggattcaactctgtgtatcatatcacagactgcccatca ttcctttcaaacaatgacattctgtgcatcttcgatccacacgcacgatatgcacctggg tcaacatctattagtcctggaagaatgtttagggacttggactctgactttagatctcaa ttctctgatgtgcttaatctttacctgggaactcatttcaagcttgaacattctacaatg ttcagattccccatacgctcaacagaaatggcaaaaatatcagagatcagctctgttgct gcctcagacagaatggtgcaaaaccttctggataaattaaaaaatgatggagcagaactc ctcatgttcctcaaccacatggagaaaatttccatctgtgaaatagaaaaacctacaggt gacctgaaggtgctatactctgtgactgctaaaattacagatggtgaccgtctgaaacgt aagcaatttcatgcctcagtggtggatagtgtgacaaaaaagaagcaactcactcaaatc ccagtccaacagataacttactcaatggatatagagaacactgatggcaatttgacaact tggatggtctgcaatcgatctggattctcctgcattgagaaagtctcaaagagtgtaata tcagcccacaaaaatgaagacattactctctttccacgtggaggggtagctgcatgtgta agccacaactacaagaagccccatagagcattctgctttttgcccttgtcattggaaact ggcttgccctttcatgttaatgggcattttgccttagattcagccaggagaaacctatgg agagatgacaatggagtaggagtaagaagtgactggaataataacttgatgacctttttg atagctcctgcctatgtggagctgatgactcaaatgaaacgacgctactttccaggacct gatcctaccatgactgtgttacaaggaacaccaatccacattgtcaaagacactttaagg aaatttctgttcttcttcccagtcaacaggcttgacatccagccagattggtactgtctt gtcaaagcagtgtacacctgcattcatgctgaccaaaaacgtctccttcctgttgttagg gcaccccagattgacaacacagacttgcattctgctgtatatatctcctgggtgaacact tcctcttcttcaaacaaaggcaaagcattctttgacaatctactacaggatgaacttcaa catctgaagaatacagaatacaacatttcctcacgtaagtctgttgcagaaaatgtcttc cgactcaaagccttgcttttggatgtgggctttaacttggttcatagttgtgatgaaaca gccagtctttacttctgtttggatgatgcaggaattccagtgagctatgttaccccaagg gatgtacgaaactttctactcacattctcttcccaagatacatcctgccaagttgggaaa cttccctgtcgactccagcagtcaaattacaagctattccacagcctgaagcttctggtt gactactgctttaaagatgttgaagaggatgaaatcgacatagtggggctaccactgctg ataacaatggacaacatactccaggtgtttgataccaagagacctagatttctgaccaca caccatgaactgatctcatcaagaaaagagctgttcatgaacacactgtacatgaggtac aacaacatcctaatgaaagcaggtgttgcaaagatctttgacatcagcagttttggggaa ctgttaagttctgttctaccacgtgaatacagaacaaggatccctgtgaaatggagagac aactacgctagtgagtcttggctaaaaggtgcatggcacttcatcagtgagaacatcgca gttaaggaagagcaggcaggtgccaaacccaattttgagactgtacttgacatactcaaa gactgggctttgctgccaggaatcaaatacatggtttcaagcaccaagctggttgtccct gatcatgacatgctgctacctttgggtttgataagcacggcaatctttccaaatgggcaa aatgacaaagtattccacactctcatgaaggggggatgcattcaggttgcagtcaacaaa atatgcgtcaaagagaatcctgtcctcactcttatggcacagcatacagcaaacattgac aatccctccagcatcctgagagcactggagtacatgattcagacatcaactttcaaaaca ggaagcttaactgacaaagactttgaggctctcctgttgtactttaactgcaatttgatc aatctcaccgaagaggatgcacaaactctgaaactgctcccatgtttcaaatcagtcagt ggcagatatatgagcattgcaaacattgggtcatgctatgttctggcaaaaagtattcct tcagcagatatggaaaaatgggcccacacaacacactttgcatttctcgctgacaatcct cagctgaaggaactctacagtttccttagatgttcactgattgatgatctggaggtctac ctgaagcatcttctaccaaagtttgacagcctgtcttatgatgccaaaattgatcacctt gtctatctgaaagacagacttatggatatagaggagtcttgtgggataaaggatcagctg tatgagaaactggaaggtctgtcaataatctatgattacaccaacagactaaaatctacc aaaatgttctatgatcaaacagtaaaggtgttcgaaatgatgctccctccaaaagcattc attcccaatgattttttcaaaaagattgaacaagtgtcaaagccaaaaaatgggacagca tttcacacctcatggatcacattcctaagaaatataggtctcagacacattgtttctcag cagcaaattctccagtatgcaaaagaggtaagcatcaaagctcaaactgagagctggtca aaagaaaaaacccaaatgattgttgatgttctccttaaccacatattcaatgagaggaca gacctatttgttggctccttccttaaggaactttccatgataccattcctgtgtcctgag cgcgcaccaactgaactcatccggctccatgctcaattccaagagatgaatggcactctc cctctaatacgtttcagtgggtctcaagtcaatccaaaattcaagcaaaccgatataatt caactgctatggacatcatgtcccattctcccagaaaaggccacaccagcagccattaaa gaccaagaaggaagcacactgactggccaagaacaactggacttagtgctgaccatgtta agtgtaaacttggaaccccccttggacaaagtgataagcaattgtaaaaatatctgtaat atatccaatcctgatgatgacatggtgaaaacaagaaacaaagtcttgagatccacctat gaatttctcaatgcagataaaagagactttcgcttccagctacgaggggtaagttttgtc atggttgaggagggttggaaacttctaaaaccagaggaagttgtcatcaacttggacaat gaatctgacttcaagccatacctatataaactaccactaccacttggcacctttcatcag ctgtttaagctcttgggaacagaagatgttgtatcaacaaaacaatatgttgaagtgatg tgccgtattcacagaaattctgagggaaaacagcttgaccctaatgaaatgagaactgtg aaaagagctgtctcagggctgttcaaaagcttacaaaatgacccagttcagatacgcaaa gaccttgagagcctgagggatttgatattttacctgccaagtcacgatggcagattagcc aaatccaacagtttagtttttgatgatgccccacactataagagcagaattcagggaaat gtaggtgttcaaatgcttgtggacatgagtcagtgttatcttggcaaggaccattccttc cacacaaagttgatcatgctgctcccaccaaagctaaggccaagactcctgagtagtatt cttgaggagcaactggacgaagagtctccaaaaatgtgccagtttggagctctctgttca cttcagggtcgccttcagcttcttctgtcttcagaacagttcatcacaggactgataaga ataatgaaacatgaaaatgacaatgcattccttgtgaatgaggaaaaagccatacgattg tgcaaagcactttgtgaaggattgaaggtgtcttgttttgagaaactacagacaacctta agagtcaaaggctgcagccctatcccgcttagccggagcgaaacacttgctttcctaaaa agatatggcacagctgttattcacctctatatccagcactcagacagcaaagacataaat tttctcttagcactggcaatgacgctgaaatctgcaacggacaacttgatatctgacaca tcatatctaattgctatgctcggctgtaacgacatctacagaattacagagaagctggac aatcttggtgtcaagtatgactccacagaaccctcaaaacttgagcttcctcttcctgga acacccataccagctgagatacaccatatactcctcatggatccaatgaatgtgttttac cctggagaatatgttggttaccttgtagactctgaaggaggagatttttatggtggatat cagcccacatacacatatgccatcattgttcaagaagtggaaaaagaagaggatgacaat ccaagcttccttggaaaatgcttccaaattgacattggatatagtgagtacaaaatagtc agttcgcttgatttgtacaaattctctagacaagaagaaagttctcatattcgagacagc agtgccccatcaactccaacaagcccctcagaatgtcactctccaggtcctggcccacga ttggtgcctccccattttactggaaaggaaaatcataaagtccctcctacaaaacaatct ccgaaaaagataagacttagcgcattgccagacatcctaaaagaagttagtttagttatt gagcaagcttggaagctctctgaaatggaaaggaagaagattattcgtcggttgtatctg aagtggcatccagacaagaatgcagagaatctagacatagctacagaggtctttaagcac ttacagaatgaaatcaacaggatggagaagcatactctgacagatcaacataacacagac agagcatccaggagaaccttctcaacatcctccacccgctttcagtcagagaagttttca tttcaaaggttttacacttcatggaaccaggaggccacaagccacaaatctgagaaacag cagttccgggagcagttcactacctatgcaggttcatcacattctaatcgcttctttgta cccccaaccttcaaatctgtgggaaatcctgtggaagcacgtaggtggcttaggcaagca agagccaatttctctgctgcacggaatgaccttcacaaaaatgccaatgagtgggtgtgt ttcaaatgctacctggctacaaaattagccttgatagctgctgattattctgtcagagga aaatccgacaaggatgtgaaacccacagcactggcacagaaagtggaggaatacaacccg cagctagcaggacttgctaaggatgttaacatactggagggatacggcgtggacagtcta agaactcgttatcctgacctgttgccctttccccagatccccaatgacagatacacatct gaggtggcaatgagagtgatggaatgtacagcacggatcatcatcaaacttgaaacgttt gtgcagcaaaaaatctaa

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