Esox lucius (northern pike): 105023553 Help Entry 105023553         CDS       T04894                                  Symbol jak2 Name (RefSeq) tyrosine-protein kinase JAK2   KO K04447   Janus kinase 2 [EC:2.7.10.2] Organism els  Esox lucius (northern pike) Pathway els04081   Hormone signaling els04148   Efferocytosis els04217   Necroptosis els04920   Adipocytokine signaling pathway els05168   Herpes simplex virus 1 infection Brite KEGG Orthology (KO) [BR:els00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04081 Hormone signaling     105023553 (jak2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     105023553 (jak2)   09143 Cell growth and death    04217 Necroptosis     105023553 (jak2)  09150 Organismal Systems   09152 Endocrine system    04920 Adipocytokine signaling pathway     105023553 (jak2)  09160 Human Diseases   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     105023553 (jak2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:els01001]     105023553 (jak2) Enzymes [BR:els01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      105023553 (jak2) Protein kinases [BR:els01001]  Non-receptor tyrosine kinases   JAK family [OT]    105023553 (jak2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 SH2_1 FERM_F1 Jak1_Phl SH2 FERM_C_FAK1 ABC1 RIO1 Kinase-like Motif Other DBs NCBI-GeneID:  105023553 NCBI-ProteinID:  XP_012992461 LinkDB All DBs Position LG14:31919967..31973915 Genome browser AA seq 1124 aa AA seqDB search MACIAVMDMDSPVCPSSNQNDCVLDPLPFSDVKQELEVVPNCLRIHLYYLGKGEANCLEL TYQPGDYVIEELCIDAAKACGFSPMYCNLFGLMRESDHMWLPPNHVLNLDKSANESLLFR VRFYFSEWYYSGRSDSHRYGVNKGLESPIIDDTVMFYLFAQWRSDFVNGWVSIPMTHETQ EECLGMAVLDMMRVAKESSQSPVDIYYDTSYKLFLPKDMRTCIQKYHYVTRKRIRHRFKK FIQQFSQCKATVRDLKLKYLVNLESLQPAFYSESFQVTEPSAGEVTIVVTGNNGIQWSKG NSVETDEGLQAYCDFPEVIDISIKQANKDGSIESRIVTINRQDNQTLELEFHSLSEALSF VSLVDGYYRLTADAHHYLCKETAPPRLLEAIQSYCHGPVSMDFAINKLRRSGNHKGLYIL RSSPKDYNKYFLSFVVGSDSQVEYKHCQVVMTDQGEYILSGAKKSFGSLRELLHRYQKEA LRSDGHIFHFTKCCPPKANEKSNLLVCRGNRGAEVPQTPSLHRHISQMVFHKIRKEDLII KDSLGQGTFTKIFCGVRKELGDYGEIHQMDVIVKILERAHRNYSESFFEAASMMSQLSHK HLLLNYGVCVCGEENMMVQEYGKFGSLDMYLKKNKSSVNITWKLEVAKQLAWAMHYLEDK SIIHGNVCAKNVLLIREEDRKGGNPPFIKLSDPGISITVLPKDVLVERIPWVPPECIEEP RDLTLATDKWAFGTTLWEICSGGDKPLCTLDCSKKRLFYEDRHQLPAPKWTELANLINSC MDYEPTNRPCFKAVIRDLNSLFTPDYELLVESDMVPNRTRGFGFPGAFENQDPTVFEERH LIFLKQLGKGNFGSVEMCRYDPQQDNTGEVVAVKKLQHSTAEHLRDFEREIEILKSLQHD NIVKYKGVCYSAGRRNLRLIMEYLPHGSLRDYLIKNKDCFDYKKLLHYASQICKGMDYLA NKRYIHRDLATRNILVESEFRVKIGDFGLTKVLPQDKEYYTVREPGESPIFWYAPESLTE SKFSVASDVWSFGVVLYELFTHSDKNCSPPAVFMDQMGSDRQGQMIVYHLIDLLKRGYRL PSPKDCTEEIYKMMTECWNVDPGQRPTFKMLAQSVDRFRDSKEG NT seq 3375 nt NT seq  +upstreamnt  +downstreamnt atggcctgcattgcagtgatggacatggattctccagtatgtccctcatccaatcagaac gactgtgtcctggacccacttcctttctccgatgtcaaacaggaactagaagtcgttcca aattgtttgaggatacacctgtactatctgggcaagggcgaggccaactgtctagagctc acctaccagcccggcgactacgtgattgaggagctgtgcattgatgccgccaaggcctgt ggcttttcaccaatgtattgcaacttatttggcctgatgagggagagcgaccacatgtgg cttccacccaatcacgtcctcaacctggacaaatcggccaatgagagtctcctcttcaga gtgaggttttacttctctgaatggtattacagtggacgctccgatagccaccgctatggg gtcaacaaaggactggagagccccatcatcgatgacactgtcatgttctacctctttgcc caatggcggagtgactttgtgaatggttgggtgagtatcccaatgacccacgagacccag gaggagtgtcttggcatggcagtgttggatatgatgagggtggccaaggagagcagccag tcccctgtggacatctactacgacaccagttataagttgttcttgcccaaggacatgcgt acttgtatccagaagtaccactatgtgacacgaaagaggatccgccatcgcttcaagaag ttcatccaacagttcagccagtgtaaagccaccgttcgcgacctcaagctcaaatatctg gtaaacctggagtcacttcagccggctttctactccgagagcttccaagtcacagagccc tctgccggagaggtcaccatcgtcgtcacgggcaacaacggaatccagtggtcaaagggg aattctgtagaaaccgacgagggtttacaggcgtactgtgatttccctgaggttatagat atcagcatcaagcaggccaacaaggacggctctattgagagtcgcatcgtcaccatcaac cgtcaggacaatcagactctggagctggagttccattccctgtcagaagcgttgtctttt gtgtcactggtggatggatactaccgcttaacagcagatgcccaccactacctttgtaaa gaaactgcgccccctaggctgctggaggctattcagagctactgtcacggcccagtctcg atggactttgctatcaataaactgcggcggtctgggaatcataagggcctgtacatcctg cgcagcagccctaaggactacaacaaatacttcctgtcgtttgtagtgggttctgacagc caggtggagtataagcactgtcaggtagtgatgacggaccagggagagtacatcctctct ggggccaagaagagttttggctcgctgagggaactgctacaccgctaccagaaggaggcg ctgcgctctgatggacacatcttccacttcaccaagtgctgtccacctaaggctaacgaa aagtcaaacctgttggtatgcagagggaaccgaggggctgaggtaccccaaaccccctcc ctccacagacacatcagccagatggtcttccacaaaattcgcaaggaggacctcatcatc aaagacagcctgggtcagggaacgttcacaaagatcttctgtggtgtgaggaaggagctt ggagactacggagaaatccaccagatggacgtcatcgtcaagattctggaaagggctcat cgtaactactccgagtcgttctttgaggctgccagcatgatgagtcagctgtcccataag cacctactgctcaactatggcgtgtgtgtctgtggagaggagaacatgatggtgcaggaa tatgggaagtttgggtccctggatatgtacctgaagaagaataaaagctctgtgaacatc acttggaagctggaagttgccaaacagctggcctgggctatgcattacctggaagataag agtattatccatgggaatgtgtgtgccaagaatgtgctgttgatccgagaagaggacagg aagggggggaaccctccgttcatcaaactgagtgaccctggaatcagcatcacagtgttg cccaaagatgtcttggtggagcgtatcccctgggtgcctcctgagtgtatagaagagccc agagatctgaccctggccacggataagtgggcctttggaacaacactgtgggagatttgt agtggaggggacaaaccactctgtacattggactgctccaagaaacgcctgttttatgag gaccgccatcagctgcctgcccctaagtggacagagctggccaatctgatcaacagctgt atggattatgagcccaccaacagaccctgctttaaagccgtcatcagagacctcaacagc ctcttcactcctgactatgagctgctggtggagagtgacatggtgcccaataggacaaga gggtttgggttcccaggggcttttgagaatcaggatcctactgtgtttgaggagagacat ctcattttcctcaaacaactgggcaagggaaattttggcagtgtggagatgtgtcggtat gatcctcagcaggacaacacgggggaggtcgtcgccgtcaagaaactgcagcacagcacg gctgaacacctcagagactttgaacgggagatcgagattctcaagtcccttcagcacgac aatattgtcaagtacaagggcgtgtgctacagcgctggtcgaaggaacctgcgcctgata atggagtacctccctcacggcagtctgagagactacctcatcaagaacaaggactgcttc gactacaagaagctccttcactatgcctcacagatctgcaaaggcatggactacctggct aacaagcgttacatacacagagacctggccacccgtaacattcttgtggagagcgagttc agggttaagataggggactttggcctcactaaggtcctgcctcaggataaggagtactac acggtcagagagccaggagagagccccatcttctggtatgccccagagtcgctgacagag agcaagttctcggtggcctcagacgtgtggagctttggagtggtcctgtacgagctgttc acccacagtgataagaactgcagtcctcccgctgtgttcatggatcagatgggcagtgac aggcagggccagatgattgtgtatcacctcattgatttgctgaaaagaggatatagactc ccttctcccaaggactgtactgaggagatttacaaaatgatgactgagtgctggaatgtt gacccaggccagcgtcccaccttcaaaatgttagcccagagtgtggacaggtttcgggac agtaaagagggctga

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