Esox lucius (northern pike): 105025897
Help
Entry
105025897 CDS
T04894
Symbol
pik3ca
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
els
Esox lucius (northern pike)
Pathway
els00562
Inositol phosphate metabolism
els01100
Metabolic pathways
els04012
ErbB signaling pathway
els04068
FoxO signaling pathway
els04070
Phosphatidylinositol signaling system
els04081
Hormone signaling
els04140
Autophagy - animal
els04150
mTOR signaling pathway
els04210
Apoptosis
els04218
Cellular senescence
els04370
VEGF signaling pathway
els04510
Focal adhesion
els04620
Toll-like receptor signaling pathway
els04625
C-type lectin receptor signaling pathway
els04810
Regulation of actin cytoskeleton
els04910
Insulin signaling pathway
els04914
Progesterone-mediated oocyte maturation
els05100
Bacterial invasion of epithelial cells
els05132
Salmonella infection
els05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
els00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
105025897 (pik3ca)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
105025897 (pik3ca)
04370 VEGF signaling pathway
105025897 (pik3ca)
04068 FoxO signaling pathway
105025897 (pik3ca)
04070 Phosphatidylinositol signaling system
105025897 (pik3ca)
04150 mTOR signaling pathway
105025897 (pik3ca)
09133 Signaling molecules and interaction
04081 Hormone signaling
105025897 (pik3ca)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
105025897 (pik3ca)
09143 Cell growth and death
04210 Apoptosis
105025897 (pik3ca)
04218 Cellular senescence
105025897 (pik3ca)
09144 Cellular community - eukaryotes
04510 Focal adhesion
105025897 (pik3ca)
09142 Cell motility
04810 Regulation of actin cytoskeleton
105025897 (pik3ca)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
105025897 (pik3ca)
04625 C-type lectin receptor signaling pathway
105025897 (pik3ca)
09152 Endocrine system
04910 Insulin signaling pathway
105025897 (pik3ca)
04914 Progesterone-mediated oocyte maturation
105025897 (pik3ca)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
105025897 (pik3ca)
09171 Infectious disease: bacterial
05132 Salmonella infection
105025897 (pik3ca)
05100 Bacterial invasion of epithelial cells
105025897 (pik3ca)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
els04131
]
105025897 (pik3ca)
Enzymes [BR:
els01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
105025897 (pik3ca)
Membrane trafficking [BR:
els04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
105025897 (pik3ca)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_rbd
PI3K_C2
PI3K_p85B
DUF2321
ABC1
Ribosomal_S15
Motif
Other DBs
NCBI-GeneID:
105025897
NCBI-ProteinID:
XP_010895234
UniProt:
A0A6Q2Y7B6
LinkDB
All DBs
Position
LG08:complement(16528008..16546635)
Genome browser
AA seq
1068 aa
AA seq
DB search
MPPRPSSGELWGIHLMPPRIFVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IHGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPTD
CFSMPSYARRISTATAYMNGETSTKSLWTINGTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLAYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSAVKFPDMATVEEHANRTISRELGFNYSQSGQSKRVARDHALTDIDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRHFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNIRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLLYGCMS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
NT seq
3207 nt
NT seq
+upstream
nt +downstream
nt
atgcctcctagaccatcttctggtgagctatggggcatccatttgatgccccccaggatc
tttgttgattgcttgttaccaaacgggatgatcctgaccctggagtgcctccgtgaggct
acgctcatcaccatcaaacatgaactgttcaaggaggccaggaagtatcccctgcatcac
ctgttacaggaggagacatcctacatctttgtcagtgttactcaagaggcagagcgtgag
gagttctatgacgaaactcgaagactatgtgatctcagactctttcaaccttttctgaaa
gtcattgaacctgttggcaaccgggaggagaaaattctgaaccgagaaattggatttgct
attggtatgcctgtgtgtgagtttgacttagtaaaggaccccgaagtgcaggacttcagg
aggaatattcttaatgtctgtaaggattcggtagaactccgagatgccaacggacctcat
agtcgggctttgtatgtttaccctcccaacgtggaatcgacacaagaacttccaaagcac
atccatggcaaactcgacaaaggtcaaatcattgtggtgatctgggtgatcgtgtctccc
aacaacgacaagcagaagtacaccctgaagatcaaccatgattgtgtgccagagcaggtg
atagccgaggccatcaggaagaagactcggagcatgctgttgtccgcagaacagctcaag
atgtgtgtgcaggagtaccagggcaagtacatcctgaaggtgtgcggctgtgacgagtac
ctcttggaaaaataccccctgagtcaatataagtacgtgcggagttgcattatgcttggt
cggatgccaaaccttatgctgatggcaaaggatagcctttactcacagttgcccaccgac
tgcttctccatgccatcctacgcccggcgcatctccaccgccaccgcctacatgaatgga
gagacctccaccaagtccctgtggaccatcaatggcacgctgcgaatacgagtgctttgt
gccacctacgttaacgtcaatatccgggacatcgataagatttatgtacgaactggcatc
taccacggaggtgaacagatgtgtgacaatgtcaacacgcagcgagttccctgctctaat
cccaggtggaacgagtggctggcttacgacatgtacattcccgacatcccccgtgcggca
cgcctctgcctctccatctgctctgtgaaaggcaggaaaggggctaaggaggagcattgt
ccactggcgtgggggaatgtcaatctattcgactacactcacacgctggtttctgggaag
atggctctgaacctgtggcctgtgccgcatggcctggaggacctgctcaatcccatcgga
gtcacaggctccaaccccaacaaggaaacgccttgtttagagctggagtttgactacttt
agcagtgctgtcaagttcccagacatggccacggtggaggaacatgctaaccggaccata
tccagggaactgggcttcaactactcccagtcaggacagagtaaaagagtggcgcgagac
catgccttaacagacattgataatgagcagctgagacaggtctgcaacagagatcccctg
tctgaaatcacagaacaggagaaggacttcctatggaggcacaggcactactgtgtaaat
atacctgaaatcctgcccaagattctactggctgtgaagtggaactcaagagatgaagta
gcgcagatgtattgcctcctgaaggattggccagcaataaaacctgagcaggccatggag
ctgctggactgtaactatccagacccaatgatccgacactttgcggttcgctgccttgag
aagtacttgaccgacgacaaactctctcagtacctcattcagttggttcaggttctgaag
tacgagcaataccttgataaccccctagtacggtttttgctgaaacgggccctgacaaac
caaaggataggacacttctttttctggcacttaaagtcagagatgcacaacaagacagtg
agccagcgatttggccttctgctggagtcctactgccgggcctgcggcatgtacctgaag
cacttgagcaggcaggtggaggccatggagaaactcatcaatctcacagacatcctcaaa
caggagaagaaggatgagactcagaaggtgcagatgaagttcctggtggagcagatgagg
aggccggactacatggatgccctgcagaacttcacctcccccctcaaccccgcacaccag
ctgggaaacatacggcttgaggagtgcagaattatgtcgtctgctaaaagacccctgtgg
ctcaactgggaaaacccagacatcatgtccgagctcctcttccagaacaatgagatcata
ttcaaaaacggagacgacctgcggcaggacatgctaacactccagatcatcagaatcatg
gagaacatctggcagaaccagggtctggacctcaggatgttgctgtatggctgcatgtcc
atcggggactgtgtgggcttaatcgaggtggtgcgaagctctcacaccatcatgcagatc
caatgtaaaggaggcctgaagggggcgctgcagttcaacagctcaacactacaccagtgg
ctcaaagacaagaacaagggagagatgtacgacatggcggttgacttgtttacccggtca
tgtgctggttactgcgtggccaccttcattctggggattggggatcggcacaacagcaac
atcatggtcaaggacgatgggcagctgttccacatcgattttggacatttcctggaccac
aagaaaaagaaatttggctacaagcgagagcgagttccatttgtcctaacccaagacttc
ttgatagtgatcagcaaagggacccaggagtgcacaaagaccagagagtttgagaggttc
caggagatgtgctataaggcatacttggcaatccgtcagcatgccaacctcttcatcaac
ctgttttccatgatgctgggctccgggatgcccgagctgcagtcttttgacgacatcgcc
tacatccgtaagaccctggcgctggacaagacggagcaggaggccctggactacttcatg
aaacagatgaacgacgcccaccatgggggctggaccaccaagatggactggatcttccac
accatccgccagcacgcactcaactga
DBGET
integrated database retrieval system
