Escherichia coli W: ECW_m0072
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Entry
ECW_m0072 CDS
T02002
Symbol
leuC
Name
(GenBank) 3-isopropylmalate isomerase subunit, dehydratase component
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
elw
Escherichia coli W
Pathway
elw00290
Valine, leucine and isoleucine biosynthesis
elw00660
C5-Branched dibasic acid metabolism
elw01100
Metabolic pathways
elw01110
Biosynthesis of secondary metabolites
elw01210
2-Oxocarboxylic acid metabolism
elw01230
Biosynthesis of amino acids
Module
elw_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
elw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
ECW_m0072 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ECW_m0072 (leuC)
Enzymes [BR:
elw01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
ECW_m0072 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
ECW_m0072 (leuC)
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Motif
Pfam:
Aconitase
Spo0M
Motif
Other DBs
NCBI-ProteinID:
ADT73623
UniProt:
E0IYV5
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Position
complement(81139..82539)
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AA seq
466 aa
AA seq
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MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFAT
MDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITA
KDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTF
NYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISV
NDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAE
IAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNP
GERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atggctaaaacgttatacgaaaaattattcgacgctcacgtagtgtacgaagccgaaaac
gaaaccccgctgttatatatcgaccgccacctggtgcatgaagtgacctcaccgcaggcg
tttgatggtctgcgcgcccacggtcgcccggtacgtcagccgggcaaaaccttcgccact
atggatcacaacgtctctacccagaccaaagacattaatgcctgtggtgaaatggcgcgc
atccagatgcaggagctgattaaaaactgcaaagaatttggcgtcgagctgtatgacctg
aatcacccgtatcaggggatcgtccacgtaatggggccggaacagggcgtcaccttgccg
gggatgaccattgtctgcggcgactcgcataccgccacccacggcgcgtttggcgcactg
gcctttggtatcggcacttccgaagttgaacacgtactggcaacgcaaaccctgaaacag
ggccgcgcaaaaaccatgaaaattgaagtccagggcaaagccgcgccgggcattaccgca
aaagatatcgtgctggcaattatcggtaaaaccggtagcgcaggcggcaccgggcatgtg
gtggagttttgcggcgaagcaatccgtgatttaagcatggaaggtcgtatgaccctgtgc
aatatggcaatcgaaatgggcgcaaaagccggtctggttgcaccggacgaaaccaccttt
aactatgtcaaaggccgtttgcatgcgccgaaaggcaaagatttcgacgacgccgttgcc
tactggaaaaccctgcaaaccgacgaaggcgcaactttcgataccgttgtcactctgcaa
gcagaagaaatttcaccgcaggtcacctggggcaccaatccaggccaggtgatttccgtg
aacgacaatattcccgatccggcttcgtttgccgatccggttgaacgcgcgtcggcagaa
aaagcgctggcctatatggggctgaaaccgggcattccgctgaccgaagtggctatcgac
aaagtgtttatcggttcctgtaccaactcgcgcattgaagatttacgcgcggcagcggag
atcgccaaagggcgaaaagtcgcgccaggcgtgcaggcactggtggttcccggctctggc
ccggtaaaagcccaggcggaagcggaaggtctggataaaatctttattgaagccggtttt
gaatggcgcttgcctggctgctcaatgtgtctggcgatgaacaacgaccgtctgaatccg
ggcgaacgttgtgcatccaccagcaaccgtaactttgaaggccgccaggggcgcggcggg
cgcacgcatctggtcagcccggcaatggctgccgctgctgctgtgaccggacatttcgcc
gacattcgcaacattaaataa
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