Escherichia coli W: ECW_m4070
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Entry
ECW_m4070 CDS
T02002
Symbol
ilvD
Name
(GenBank) dihydroxyacid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
elw
Escherichia coli W
Pathway
elw00290
Valine, leucine and isoleucine biosynthesis
elw00770
Pantothenate and CoA biosynthesis
elw01100
Metabolic pathways
elw01110
Biosynthesis of secondary metabolites
elw01210
2-Oxocarboxylic acid metabolism
elw01230
Biosynthesis of amino acids
Module
elw_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
elw_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
elw00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ECW_m4070 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
ECW_m4070 (ilvD)
Enzymes [BR:
elw01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
ECW_m4070 (ilvD)
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Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
ADT77396
UniProt:
E0J420
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Position
4177912..4179762
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AA seq
616 aa
AA seq
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MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLV
AEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCIS
NCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDSQ
SDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIV
ELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSD
IDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQT
LEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDSLDDDRANGCIRSLEHAYSKDG
GLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRY
EGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGL
IEDGDLIAIDIPNRGIQLQVSDAELAARREAQEARGDKAWTPKNRERQVSFALRAYASLA
TSADKGAVRDKSKLGG
NT seq
1851 nt
NT seq
+upstream
nt +downstream
nt
atgcctaagtaccgttccgccaccaccactcatggtcgtaatatggcgggtgctcgtgcg
ctgtggcgcgccaccggaatgaccgacgccgattttggcaagccgattatcgcggttgtg
aactcgttcacccaatttgtaccgggtcacgtccatctgcgcgatctcggtaaactggtc
gccgaacaaattgaagcggctggcggcgttgccaaagagttcaacaccattgcggtggat
gatgggattgccatgggccacggggggatgctttattcactgccatctcgcgaactgatc
gctgattccgttgagtatatggtcaacgcccactgcgccgacgccatggtctgcatctct
aactgcgacaaaatcaccccggggatgctgatggcttccctgcgcctgaatattccggtg
atctttgtttccggcggcccgatggaggccgggaaaaccaaactttccgatcagatcatc
aagctcgatctggttgatgcgatgatccagggcgcagacccgaaagtatctgactcccag
agcgatcaggttgaacgttccgcgtgtccgacctgcggttcctgctccgggatgtttacc
gctaactcaatgaactgcctgaccgaagcgctgggcctgtcgcagccgggcaacggctcg
ctgctggcaacccacgccgaccgtaagcagctgttccttaatgctggtaaacgcattgtt
gaattgaccaaacgttattacgagcaaaacgacgaaagtgcactgccgcgtaatatcgcc
agtaaggcggcgtttgaaaacgccatgacgctggatatcgcgatgggtggatcgactaac
acagtacttcacctgctggcggcggcgcaggaagcggaaatcgacttcaccatgagtgat
atcgataagctttcccgcaaggttccacagctgtgtaaagttgcgccgagcacccagaaa
taccatatggaagatgttcaccgtgctggtggtgttatcggtattctcggcgaactggat
cgcgcggggttactgaaccgtgatgtgaaaaacgtacttggcctgacgttgccgcaaacg
ctggaacaatacgacgttatgctgacccaggatgacgcggtaaaaaatatgttccgcgcc
ggccctgcgggtattcgtaccacacaggcattctcgcaggattgccgttgggattctctc
gatgacgatcgcgccaatggctgtatccgctcgctggaacacgcctacagcaaagacggc
ggcctggcggtgctctacggtaatttcgcagaaaacggctgcatcgttaaaaccgcgggc
gtcgatgacagcatcctcaaattcaccggcccggcgaaagtgtacgaaagccaggacgac
gcggtagaagcgatcctcggtggcaaagttgtcgcgggcgatgtggtggtgatccgctat
gaaggcccgaaaggcggccctggcatgcaggaaatgctctacccaaccagcttcctgaaa
tcaatgggtctcggtaaagcctgtgcgctgatcaccgacggtcgtttctctggcggcacc
tctggtctttccatcggccacgtctcaccggaagcggcaagcggcggcagcattggcctg
attgaagatggtgacctgatcgctatcgacatcccgaaccgtggcattcagttacaggta
agcgatgccgaactggcggcgcgtcgtgaagcgcaggaagctcggggtgacaaagcctgg
acgccgaaaaaccgtgaacgtcaggtttcctttgccctgcgtgcctacgccagcctggcg
accagcgccgacaaaggtgcggtgcgcgataaatcgaaactggggggttaa
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