Epinephelus lanceolatus (giant grouper): 117247624
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Entry
117247624 CDS
T07331
Symbol
top2a
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
ely
Epinephelus lanceolatus (giant grouper)
Brite
KEGG Orthology (KO) [BR:
ely00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ely03032
]
117247624 (top2a)
03036 Chromosome and associated proteins [BR:
ely03036
]
117247624 (top2a)
Enzymes [BR:
ely01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
117247624 (top2a)
DNA replication proteins [BR:
ely03032
]
Eukaryotic type
DNA Topoisomerases
117247624 (top2a)
Chromosome and associated proteins [BR:
ely03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
117247624 (top2a)
Centrosome formation proteins
Centriole proteins
117247624 (top2a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Motif
Other DBs
NCBI-GeneID:
117247624
NCBI-ProteinID:
XP_033468100
LinkDB
All DBs
Position
21:complement(17083936..17097150)
Genome browser
AA seq
1580 aa
AA seq
DB search
MAEPLKSLFENKPVEKTKKDPKRLSVERIYQKKTQLEHILLRPDSYIGSVEPVTQQMWVY
DEDEGLNCRDVTFVPGLYKIFDEILVNAADNKQRDKNMNCIKINIDVENNTISVWNNGKG
IPVVEHKVEKVYVPALIFGQLLTSSNYNDDQKKVTGGRNGYGAKLCNIFSTKFTVETACK
ESKKTFKQTWYDNMGRAGDSNIKSFDGEEYTCITFKPDLVKFKMTILDKDTVALMTRRAY
DIAGSTKGVRVYFNGKKLPITGFRSYVDMYVKDKVDELGGALTVVHEIVNERWEVCLTMS
EKGFQQVSFVNSIATTKGGRHIDYVADQVVGKLIEVVKKKNKAGVAVKPFQVKNHLWVFV
NCLVENPTFDSQTKENMTLQQKSFGSTCPLSDKFIKQATSCGIVESIMNWVKFKAQTQLN
KKCSSVKHTKIKGVPKLDDANDAGGKNSIGCTLILTEGDSAKTLAVSGLGVVGRDRYGVF
PLRGKMLNVREASLKQIMENAEINNIIKILGLQYKKNYSDPESLKTLRYGKIMIMTDQDQ
DGSHIKGLLINFIHHNWPSLLRHNFLEEFITPIIKASHKKTQLSFYSIPEFNEWKENQPN
FKSWKIKYYKGLGTSTSQEAKEYFSDMQKHRIPFKYSGPEDDEAITLAFSKKKVEERKEW
LTNFMNNRRQRKAHNLPEEYLYGQTTKSLSYNDFVNKELVLFSNSDNERSIPCLVDGMKP
GQRKVLYCCFKRNDKREVKVAQLAGSVAEMSAYHHGEVSLMMTIVGLAQNFVGSNNLNLL
QPLGQFGTRLHGGKDSASPRYIFTMLSSLARLVFPSVDDNLLKYNYDDNQRVEPEWYMPI
IPIVLVNGSEGIGTGWASKLPNYDIREIVSNIHRMLNGDEPLPMLPNYKGFKGTIEQVMD
NQYINSGEVAIIDSTTIEISELPVKTWTQAYKENVLEPMLNGTEKAPPLITDYKEYHTDT
TVRFVIKMTAEKLSEAEAAGLHKVFKLQTALTCNSMVLFDHVGSLKKYESVQDILKDFFE
LRMKYYMLRKDWLVGMLGAESAKLTNQARFILEKIQGTLVIENKPKKELIRMLQQMGYDS
DPVKAWKEAQEKNQEEEVVEEEEEEETEKDTSGPDYNYLLSMPMWYLTKEKKDELCKQRD
AKMTELNTLKKKSPADLWKEDLAAFCEELENIEAKEKENASMPIVKKGAGRGKAVKVKQE
TLPTPQGRRVVPRVTSTMKAEANRKADLKKGEGKRGRKVKTEDVVMKMEFGEDAENTEPS
EEMGLAARLGKKTKTQTKEKAAASKTSKQGTLQFQPVAKKTKKNPWSDEESGSLSNSEIE
AEEVAAPRERVERKTKAAVKYNMSDSENEFDDWGKEGAPKRKAAISDDDDDSFVPEPMAD
SEVDSPAPPPKAPEPMKKTVKSKSTVKQAKTTSSSQSDDQVPAPKAPVQRKTKEAAPKKA
AAAKKPAAPKKKATDAKQPSILDALSKSKPASNTAAKKVPSFDSSDSEGEVKAPVTKAKP
IVKRKQIASDDSDSSSDNLMSRIKGKTTANKKIKKWDDDESFQVSDQEEAAPVSKAPRDK
PSRARKPVTYNLDSDSDEDF
NT seq
4743 nt
NT seq
+upstream
nt +downstream
nt
atggctgaaccactgaagtccctctttgaaaacaagccggtggagaagacgaagaaagat
ccgaagcggctgtcagtggagaggatctatcagaagaagacgcagttggagcacattttg
ctccgaccggactcctacataggctctgtagagcctgtcacccaacaaatgtgggtgtat
gatgaggatgaaggactgaactgccgtgatgtgacatttgtgcctgggctttacaagatt
tttgatgagatccttgtaaatgcagctgacaataagcagagggataagaacatgaactgt
atcaagatcaacattgatgttgaaaacaacaccatcagtgtgtggaataatgggaagggt
attcctgtagtggagcacaaggtggagaaggtctatgtgcctgctctcatctttggacag
ctccttacctccagtaactacaatgatgaccagaagaaagtcactggtggacgcaatgga
tatggtgctaagctttgcaacatctttagcacaaagttcaccgtagagactgcctgtaaa
gaatcaaagaagaccttcaagcagacttggtatgacaacatgggcagggcaggtgatagt
aacatcaaatcctttgacggagaggaatacacctgcatcaccttcaagccggacctcgtc
aagtttaaaatgaccatcctggacaaagatacggtggctctgatgaccaggagggcatac
gacatcgctggatccaccaaaggtgtccgtgtgtacttcaacggcaagaagctgccaatt
acaggtttccgtagctacgtggacatgtatgtaaaggacaaggtggacgagcttggcggt
gccctcactgtagtccacgagattgtcaacgagcgctgggaggtctgcctcaccatgagt
gagaaaggtttccagcaagtcagctttgtcaacagcatcgccacgaccaagggagggagg
cacatcgactacgtggccgaccaggtggttggcaagctcattgaagtggtaaagaagaag
aataaagctggggtggctgtcaagcctttccaggtgaagaaccacctgtgggtgtttgtc
aattgcctggttgagaaccccacctttgactctcagaccaaagagaacatgactctgcag
cagaagagctttggatcaacttgtcctctcagtgacaagttcattaagcaggctacatcc
tgtgggattgtggaaagtatcatgaactgggtgaagttcaaggctcagacccagctaaac
aagaaatgctcaagtgttaaacacacaaaaatcaaaggagtgcccaaactggatgatgcc
aacgatgcaggtgggaagaactccatcggctgcacactgatcctcactgagggagactcg
gccaagacacttgctgtgtctgggctgggagtggtcggcagggaccgctatggcgtcttc
cctctcaggggaaaaatgctcaatgttcgggaggcctcactcaaacagatcatggagaat
gctgaaatcaacaacatcatcaagatcctcggccttcagtacaagaagaactacagtgac
ccagaatccctcaagaccctgcgttatggcaagatcatgattatgacagatcaggatcaa
gatggctcccacattaagggccttctgatcaacttcatccaccataactggccatcactg
ctgcgacacaacttcctggaagagttcatcacccccatcatcaaggcatctcacaagaaa
actcagctgtctttctacagtatccctgaattcaacgagtggaaggaaaaccagcccaat
ttcaaatcttggaaaataaaatactacaaaggtttgggaaccagcacatcgcaagaagca
aaggagtacttctctgatatgcagaaacaccgtatcccattcaagtactctggacctgaa
gacgatgaagctatcacccttgcctttagcaagaagaaagtggaagagcgtaaagagtgg
ctgaccaacttcatgaacaacagacgccagcgcaaggctcacaacctgcctgaggagtac
ctgtacggtcagaccaccaaatctctttcgtacaatgactttgtcaacaaggagctggtc
cttttctccaactctgacaatgagaggtcaatcccctgcctggtggatggtatgaaacca
ggccagaggaaggtgctgtactgttgcttcaagaggaatgacaagcgggaggtgaaggtg
gcccagttggccggctcggtggctgagatgtcagcctaccaccatggagaggtctctctg
atgatgaccattgttggtttggcccagaactttgtcggaagcaacaacttgaacctgctg
cagcctctgggtcagtttggaaccaggttgcatggtggcaaggactccgccagccctcga
tacatcttcaccatgctcagctccctggcccgcctcgttttcccatctgtggacgacaac
ctgctcaagtacaactatgatgacaaccagcgcgtagagccggagtggtacatgcccatc
atccccattgtgctggtgaacggctccgaaggtattggcacaggctgggccagcaagctc
cccaactacgacatccgagagatcgtcagcaacatccaccgcatgctcaacggtgatgag
cctctgcccatgcttccaaactacaaaggcttcaaagggacaattgagcaggtgatggac
aaccagtacatcaacagtggagaggtggccatcattgattcaaccaccattgagatctct
gaattgccagtcaaaacctggacgcaggcctacaaggagaacgtgctggagccaatgttg
aatggcacagagaaggcccctcctctgatcacagactacaaggaataccacactgacacc
actgtgcgctttgtgattaagatgaccgcagagaagctgagtgaagcagaggctgctggt
ctccacaaagtcttcaaactacagaccgccctcacctgcaactctatggttctgtttgac
catgtgggcagcctgaagaagtatgagtctgtgcaggatattctcaaagacttctttgag
ttgaggatgaagtactacatgctgagaaaggactggttggtcggcatgctgggggcagag
agtgctaaactcaccaatcaggcccgcttcatcctggagaaaatccagggcaccttggtc
attgagaacaagccaaagaaggaactcattcgcatgctgcagcagatgggctacgactct
gacccagtcaaggcttggaaagaggctcaagagaagaaccaggaagaagaggtggtggag
gaagaggaagaggaggaaacggagaaggacaccagcgggccagactacaactacctgctg
agcatgcccatgtggtacttgaccaaagagaagaaagatgagctgtgcaagcagagggat
gctaagatgacagagctgaacacgctgaagaagaagtctccagccgacctgtggaaggaa
gacctcgctgctttctgcgaggaactggagaacattgaggccaaagagaaggagaacgcc
agcatgcccatcgttaaaaagggggctggaagaggcaaagcagtgaaggtgaagcaagag
actctgcccacaccacagggtcgccgcgtcgtcccgcgtgtcaccagcaccatgaaagct
gaagctaacaggaaggctgatctcaagaaaggagaaggcaagaggggcaggaaagtcaag
actgaagacgtcgtgatgaagatggagtttggagaagatgctgagaacacagagccaagt
gaagagatgggcttggctgcacgacttggcaagaaaactaaaacccagacaaaggaaaaa
gcagcagcatcgaagaccagcaagcagggcactcttcagtttcaacccgttgccaagaag
accaagaagaatccgtggtcagatgaggagtctggcagtctgtccaacagtgaaatcgag
gcagaggaagtggctgcccccagagagcgagtcgaacgcaaaactaaagctgcggtgaag
tacaacatgtccgacagtgaaaatgaatttgatgactggggaaaggagggcgctccaaag
cggaaagctgccatcagcgacgatgatgatgacagctttgtccccgagcccatggctgac
agcgaagttgactctccagcccctccccccaaagctccagaacccatgaagaaaacagta
aagagcaaatctacagtgaaacaagctaaaaccacttcaagctctcaatcagatgatcag
gtgcctgcacccaaggctccagttcaacgtaaaacaaaggaggcagcacccaagaaggct
gctgctgctaagaaaccagctgcacccaagaagaaggctacagacgcaaagcagccatcc
atcctggatgctctgtccaagtccaaacctgcgtccaacacagctgccaagaaggtccct
tcatttgactccagtgactcagagggtgaagtcaaagctccagttacaaaggccaagcct
attgtgaaacggaaacagatcgccagcgacgactccgacagcagctcagacaacctcatg
tcacgcatcaagggcaaaacaactgccaacaagaaaatcaagaagtgggacgatgatgaa
agcttccaggtttcggaccaggaagaagcagctcctgtatccaaggcaccgcgagacaag
ccctcacgtgcccgcaaacctgtaacctacaacctggactcagattcagatgaagacttt
taa
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