Epinephelus lanceolatus (giant grouper): 117253448
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Entry
117253448 CDS
T07331
Symbol
pik3ca
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
ely
Epinephelus lanceolatus (giant grouper)
Pathway
ely00562
Inositol phosphate metabolism
ely01100
Metabolic pathways
ely04012
ErbB signaling pathway
ely04068
FoxO signaling pathway
ely04070
Phosphatidylinositol signaling system
ely04081
Hormone signaling
ely04140
Autophagy - animal
ely04145
Phagocytosis
ely04150
mTOR signaling pathway
ely04210
Apoptosis
ely04218
Cellular senescence
ely04370
VEGF signaling pathway
ely04510
Focal adhesion
ely04517
IgSF CAM signaling
ely04518
Integrin signaling
ely04620
Toll-like receptor signaling pathway
ely04625
C-type lectin receptor signaling pathway
ely04810
Regulation of actin cytoskeleton
ely04910
Insulin signaling pathway
ely04914
Progesterone-mediated oocyte maturation
ely05100
Bacterial invasion of epithelial cells
ely05132
Salmonella infection
ely05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
ely00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
117253448 (pik3ca)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
117253448 (pik3ca)
04370 VEGF signaling pathway
117253448 (pik3ca)
04068 FoxO signaling pathway
117253448 (pik3ca)
04070 Phosphatidylinositol signaling system
117253448 (pik3ca)
04150 mTOR signaling pathway
117253448 (pik3ca)
09133 Signaling molecules and interaction
04081 Hormone signaling
117253448 (pik3ca)
04517 IgSF CAM signaling
117253448 (pik3ca)
04518 Integrin signaling
117253448 (pik3ca)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagocytosis
117253448 (pik3ca)
04140 Autophagy - animal
117253448 (pik3ca)
09143 Cell growth and death
04210 Apoptosis
117253448 (pik3ca)
04218 Cellular senescence
117253448 (pik3ca)
09144 Cellular community - eukaryotes
04510 Focal adhesion
117253448 (pik3ca)
09142 Cell motility
04810 Regulation of actin cytoskeleton
117253448 (pik3ca)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
117253448 (pik3ca)
04625 C-type lectin receptor signaling pathway
117253448 (pik3ca)
09152 Endocrine system
04910 Insulin signaling pathway
117253448 (pik3ca)
04914 Progesterone-mediated oocyte maturation
117253448 (pik3ca)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
117253448 (pik3ca)
09171 Infectious disease: bacterial
05132 Salmonella infection
117253448 (pik3ca)
05100 Bacterial invasion of epithelial cells
117253448 (pik3ca)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ely04131
]
117253448 (pik3ca)
Enzymes [BR:
ely01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
117253448 (pik3ca)
Membrane trafficking [BR:
ely04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
117253448 (pik3ca)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_rbd
PI3K_C2
PI3K_p85B
ABC1
Ribosomal_S15
Motif
Other DBs
NCBI-GeneID:
117253448
NCBI-ProteinID:
XP_033476785
LinkDB
All DBs
Position
6:33752631..33787375
Genome browser
AA seq
1068 aa
AA seq
DB search
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDANGPHSRALYVYPPNVESTQELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYIRSCIMLGRMPNLMLMAKDSLYTQLPTD
NFVMPSYSRRISTATSYMNGEAAAKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVANKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SSSVKYPEMNAVEDHANWTISRELGFNYNLSGQSNRSARDHALTESDTEQIRQLSNRDPL
SEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAME
LLDCNYPDPMVRQFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMRFLVDQMKRPDYMDALQNYTSPLNPAHQLGNLRLDECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLS
LGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNKGEMYDMAVDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGSQECAKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALEKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHALN
NT seq
3207 nt
NT seq
+upstream
nt +downstream
nt
atgcctcccaggccgtcctcaggggagctatggggcatccacttgatgcctcccaggatc
ctggtggactgcctgctgcccaatgggatgattcttaccctggagtgtctccgtgaggcc
acgctcatcaccatcaaacatgagctgttcaaagaggccaggaaatatcccctccatcac
ctcctacaggaagagacgtcctatatcttcgtcagtgttacacaggaagcagagcgggaa
gagttctatgatgagacccgaaggctgtgtgatctccgactcttccagcccttcctcaag
gtcatcgaaccagttggcaacagggaggaaaagatcctcaacagagagattggttttgcc
attggtatgcctgtgtgtgaatttgaccttgtgaaggacccagaggttcaggacttcagg
agaaacatcctgaatgtttgtaaagactctgtggagctgagagatgccaacgggccccac
agtagagcactgtatgtttacccacccaatgtggaatccacacaggaacttccaaaacac
atctataacaaactggacaaaggtcaaattattgttgtgatttgggtgattgtttctcca
aacaacgacaaacaaaagtacacattgaagatcaaccacgactgtgtgcctgaacaggtg
attgctgaggccattcgtaagaagacacgcagcatgctgttgtccccagagcagctaaag
atgtgtgttcaggaatatcagggtaaatacatcctcaaagtttgtggctgtgatgagtac
ctgctggaaaagtaccccatcagccaatataagtatatccgtagttgcatcatgctgggc
aggatgcctaacctgatgctaatggccaaggacagcctatacactcagttgcctacagat
aactttgtcatgccatcgtactctcgacgcatctccacggcaacatcctatatgaatggt
gaggcagctgccaagtcgctgtggaccatcaacggaacgctgcgaatccggatcctatgt
gccacctatgttaacgtcaatatacgggacatagacaagatatatgtgaggacaggtatt
taccatggaggtgaacagatgtgtgacaatgtcaacactcagagagtaccctgctctaac
cccaggtggaatgagtggctcacgtatgatatgtacatcccagacataccccgtgctgcc
agactctgcctgtccatctgctctgtcaagggcaggaagggagccaaggaggagcactgt
ccactggcgtggggtaatatcaacttgtttgactatactcacactctggtggccaacaag
atggctctgaacctctggcctgtccctcatggccttgaagacctcctcaaccccatagga
gtcactggatccaaccctaataaggaaaccccatgtctggagctggagtttgaccacttc
agtagttcagtcaaatacccagaaatgaatgcagtcgaggatcatgcaaactggaccatc
tcaagggaactgggctttaactacaacctctctggacagagcaaccggtcggccagagat
cacgccctgacagagagcgacactgagcagataagacagctgagtaacagagaccctctt
tcagaaatcactgagcaggagaaagacttcctctggagacacaggcactactgcatgaat
atccctgagatccttcctaagatccttctcgctgtcaaatggaactccagagatgaagta
gcacagatgtactgtctgttaaaggaatggccatctatccgtcctgagcaggccatggag
ctgctggactgtaactatcccgaccccatggtcaggcaatttgctgtgcgctgtcttgaa
aaatacctgactgatgacaaactgtctcagtacctcatccagcttgtacaggtattaaaa
tatgagcagtatcttgacaatccgctggcccgtttcctcctcaaaaaggccctgaccaat
caaaggataggtcatttcttcttctggcatctcaagtcagaaatgcacaataaaacagtg
agccagaggtttgggctgctgctagaggcttactgcagggcatgtggcatgtacctcaaa
cacctgagcaggcaggtagaagccatggagaagctcattaacctcactgacatccttaaa
caggagaaaaaggatgagacacaaaaggtccagatgcggtttcttgtggaccagatgaag
agaccggactacatggatgctctgcagaactacacttctcctctcaaccctgcacaccaa
ctgggaaacttgaggttagatgaatgcaggatcatgtcatcagcaaagaggccattgtgg
ctgaactgggagaatcctgacatcatgtccgagctgctctttcagaacaatgagatcatc
ttcaaaaatggagatgacctgcggcaggatatgctgacgttgcagattattaaaatcatg
gagaatatttggcagaatcagggacttgacctcaggatgcttccgtatggctgtctgtca
ttaggagactgtgtgggtctcatcgaggtggttcgcagctcccacaccatcatgcagatt
cagtgtaaaggaggcttgaaaggagccctgcagttcaactcaaacactctgcatcagtgg
ctcaaggacaagaacaagggcgagatgtacgacatggctgttgatctttttacgaggtcc
tgtgctggctactgtgtagctacatttattcttgggataggagacagacacaacagcaac
attatggtcaaagatgatggacagttgtttcatatagatttcggccatttcctggatcat
aagaagaagaaatttggctacaagagagagcgagttccttttgtactgacacaagacttc
ctcatcgtcatcagcaagggatcccaggagtgcgcaaagaccaaagagtttgagaggttc
caggagatgtgttataaagcctacctggccatccgacagcatgctaacctcttcattaac
ctgttctccatgatgctgggctctggcatgcctgagctgcagtcatttgatgacattgcc
tacattaggaagacgctggccctggagaaaactgaacaggaggctttggactactttatg
aaacagatgaatgatgctcaccatggaggatggaccaccaagatggactggatattccat
acaattagacagcatgcactaaactga
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