Epinephelus lanceolatus (giant grouper): 117254186 Help Entry 117254186         CDS       T07331                                  Name (RefSeq) obscurin-like isoform X1   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism ely  Epinephelus lanceolatus (giant grouper) Pathway ely04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:ely00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     117254186  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ely01001]     117254186   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ely04131]     117254186 Enzymes [BR:ely01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      117254186 Protein kinases [BR:ely01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    117254186 Membrane trafficking [BR:ely04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     117254186 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase Ig_5 PK_Tyr_Ser-Thr Izumo-Ig Ig_4 Ig_CD22 SOS1_NGEF_PH Ig_6 C1-set RhoGEF C2-set_2 fn3 Kdo IQ PH IQ_SEC7_PH Pox_ser-thr_kin APH Lep_receptor_Ig Motif Other DBs NCBI-GeneID:  117254186 NCBI-ProteinID:  XP_033478156 LinkDB All DBs Position 5:26814338..26856944 Genome browser AA seq 6388 aa AA seqDB search MGDNIPGGIVAAAKNRLQVVKGLEDVQVSECESCSFDVTLNLAYIEGVWTRDGLRLKSKP TCRISTHGKKHSLILSRVALGDAGLFSFQAPGIQTSARLTVTARDIHIVTELEDVDTVER QPVNFVCEVNQVDLEGRWYRDDSRIRPGDNIKIRHQGKTHTLCFKSVRPEHAGEIRFTAE RVSSYATLTVKELPVQIVRPLRVKIAMYRHRGLLECQVSRPNAQVTWYKNRKELVPNKKY QMISQDVYRQLTIDDICSSDEDTYTCDAGDDNTSCQLLVEEQAISIVRGMSSVEVTEPEP ALFQVETSLKSGRPPRWTLNGEVLEPCAAVNIDRQGTLHSLCFTYTESSMSGPVLFVAGK SRSTAQLTVKERPLQVAHHLENAEAKENSSVTLSCAFVPSPRVVRWFKGRTALKTNNKYS MKREGKRAQLTIHGLSAMDAGQYRCMAGGAQSTAHVKVEVRTLKLVKHLEPVEIEEDSIA RFTCELNYVVANVEWLLNNVRLYCNAINRIQHMGTMHSLTIKNPRPQESRVTFKAGLLSE TTILKVKEHPAVFLRSLEDVVGEEQGEVCLQCEISKEKVTPVWRKDGEILTTDDKHELLQ SGKSMALIIHSLSKDDAGHYTCDLGTSQTKAKVTVHDLRITIVHRIKITSVQEGECCTFD CQLSHDLDDEPSWTINGQLVVTNSRIQVINNGRHYKMTIRDALLTDAGDVVFTIKDLSCR TMLFVKEKPVHIFRELLNTKAVPGEDAELSCEITKPEVLIRWLKNGRLIRPSPKYVMSVE KNLARLVIKNSTIRDSGEYCCEADGIASRAKLEIRELQHTFARELRDTRAEEKGKVTLEC ETRRPAKRVTWLKGMVELRSGRKYVIRQKGVVLSLTITCLDKSDTDIYICDVGTMQSRAQ LTVQGQRVLILDELEDVECLEGDTVTFKCRICPSDYIGVKWYLDETLLYTNELNEIQMVA GGYHTLTFRQLARKDTGTISFSAGDKRSYASLLVRERRPTIIKALEDCEAIEGGGLVLSC VASKPCHILWYKDGCLMWNSSRYFASRSGCEARLTIREVSNNDAGVYECSAGSVTTRAVV TVRAIPAEFIQALKSLEAKEGETVTLTCEYSLPGVQCHWKRGFESIRPGDRYLIKQRKTI NSLTIKALKPLDSGEYTCQCRDHHTTASLKVHAIPITFIQKLKNMQAEEGSNVLLRCELS KPGIPAEWRKEHELLKNGVKYQIRKRETTLELLIWKPVPEDSGVYSCACADQITSATVKI TALPVTFKQKLRNVLIEEGSTAALRCELSKPGYSVEWRKSGDELIRNGEKYHIRQRDGLI ELRILDVRPEDSDIYTCICGDIETTATLTVNALPITFKQKLKNVQVEEGHNITLYCEISK AGVPVEWRLGGDLLENGEKYQIKQRASALELIIRDAEPDDSGVYTCVCREQKTKATVKVI AVPTTFKVSLKGQEAEEGKSVTLRCELSKKGVQVQWQRDAQVLSEFTYRGKYLIKLEGKT AEMTIVNVQPEDAGKYSCITGDEKTTAEVKVKPLPVTFKREIQRMVVKEGDSGVFSCEIS KPGAPVEWRKGRTILKPGNKYEMKLEGPFAKLVINDVEESDGGKYTCKTKDSQSTAELIV QDLPASFKMPLVNQEATEGNSVVLRCELNKPAPSVEWRRGSELLKNGDKYQMRKKDLQVE MKITELSLDDAGDYTCICGEHSTQARITVNERPIKFLQELKNIQVQEGNGVTLCCELSKP DTPVQWKKGDKVLTNGEKYQMKQSGSKVELLIRKSQPEDSGSYSCVCEDVKTTATIIITG IPITFKQKLRNQEAVEEGNVTLRCELSKAGVPVEWRKDAQLLMEGEKYQMKQEGRTAEML IRNLTLKDLGEYSCFVGTVVTSADIKVRALPVIFKQELEKLEVKEGDSGVFSCELSKPGA PVDWRKGRVILKPGYKYEMKQEGRFTKLIINNVEESDAGKYTCKTNDTQSTAELIVKAPP ITFKTKLRNQQVEEENSVTLNCELSKPGLPVEWRKGQELLKSNFKYQIKNRNSNMELTIK NAQLEDSGLYSCIYGDTKTTANITITPIPLTFKMGLKNQEAPEGGNVSLHCELSRAGVPV QWWKGEDQIYQGGRYQMTLKGKTAEMNIRNIQPEDVGEYSCIVGEQKTTAEVNVRAAASV FFEKELESQAVMEGKSVLLSCEVSSANVPVTWKKDNTVIEEGGRYILKKKGPTHSLEIKK LHLEDAGEYCCITRGKKTTAKLIVRASSSSTERVRIVTELQGITVTAGEDAVFVCELSHA DVSEGVWWLGSSPLQKNEMNQMMCHGREQRLVLTMTTPEETGIVAFVIGEERTSARLLVV PKARVLFEEKPKDVVIMEGETATLSCTISDFTSLVTWRRNHIPLRNGDKYEIRKEGKVNL LLIHDVDPLDTGTYCCDTGDVQSSAKLTVTELPPFFQEELQSVEVEEGGSAALYCELSKL GVPIQWKKKGLPLRASQKYEIRQDGCLLQLHIKDLKLEDSGSYSCQAGSAETTATVTVKE LPPFFKKELRSVEAEEGGTASLCCELSKAGVSVQWKKNRLPLKASRKYEIKQDGCLLQLH INELKPEDRGSYTCQAGSAETTATVSVKELPPFFKEELQSVKVNEGGTASLCCEVSKPGV SVQWKKIKLPLRASRKYEMKQDGCLLQLHIKELQPEDSGSYTCQAGHVETTATVTVKEVP PFFKEELQNVKVEEGATTSLCCELSKPGVSVQWKKNRLPLRASRNYEMKQDGCLLQLYIK DLKPEDSGSYSCQAGSAETTATVTVKELPPFFKEDLESLEVDEGGTATLCCELSKPGVSV QWSKNRLPLRANRKYEMKQDGCLLQLHIKDLKPEDSGSYSCQAGSAETTATVTVKELVPF FKEDLLSVEAVEGGSASLCCELSKPGLSVQWSKNKLPLRANRKYEMKQDGCLLQLHIKDL KPEDSGCYSCEAGRAETTATVTVKELAPFFKEDLVSVEAEEGGSASLCCELSKAGVFVQW SKNKLPLRANSKYEMKQDGCLLQLHIKELQPEDSGSYTCQAGRVETTATVTVKELPPYFM EDLQSVEAEEGATTSLCCQLSKPGVSVQWKKNRLPLRANRKYEMKQDGCLLQLHIKDLKP EDSGSYSCQAGSAETTATVTVKELPPFFKEGLQSVEAQEGGTASLCCELSKPGVSVQWKK NKLPLRANRKYEMKQDGCLLQLHIKDLKPEDSGSYTCQAGLVETTGTVAVKEKPPLFKKD LLSVEAEEGATASLCCELSKAGVSVQWKKNKLPLRANRKYEMKQDGCLLQLHIKDLKPED SGSYTCHAGSAETTAAVTVKELPAFFKEYLESVEVKEGDTASLCCELSKPGVSVQWKKNG IPLKAGNKYEIKQGGCLLQLYIKDLKVEDSGSYTCQAGSAETTATVTVKALEPAPPKAEP PTILPRAKGPVSKPTPAPESQKPGLPEAKPVPPEPKKRAHRKASIASLEKDVEPMFDLKQ GIQPARSMEKDLDVAQNIIQLERHVEKDNELNKKVDKTVRPLEKDNRVDREVEEPARPLE TEKDVLMERRQPGRITEKLVQVDHNASETDKVVGDTVFEQKKRKDEVEQILKQAVKPSER TSEVERNESHPEKVQWEKSEDEKPSVKPLEKFIGSKTIKDQEEKFIVKEGKVEEEEPFKP PVRSKGKVTGAKEPPQYVPKKTEEIIVQTVKPTVNEFEEDNRQRDHVKQQVSMEAENEIK PLKLVTSANKLDKQPLEKEAEFAPPKPPARVKSRAKGGMERQSSRDTETDQDDLQVTRVV VKTKEDQPVKLSITSLVKEVEEKPRSERKQSVTTDTETAEKIRQPVKAAEKDAITKQPIK QPVKPMRKEPEVDQEIKLAVEPMRREEEAQTVKMAEDIPLLYISEDETFSEALTEIPLNR NDVQPPGFFVEGSTQPATLPPVNVPQKAQPLNEAAPEIDIDIEDEPQLQEAAIKIQAAFK GYKTRKDMRPVFKEVFKNQSADLHGTITLVCVVEGKPSSVRWLKNGQQITNDYRCRIETT ENGMCTLVIKNLTTSDSGIYTCEVVNKFGVTSYNGNITVVQPQKPAPVVQKPIHPPLAAI TPLQLAPQKPEEETQTQDLPQTQTQTPPSAADAENYVENVSVSLWEAYNLTEQDAQARLQ ERRGSSLIAASSMSSPSDYETAPDIMEPVETGPTVQLRVETKAVDQVPPEDEEQPPQPTK TLLKVKAAHEGKMRTPSPKHHHAHTPLTSTVSGSESEGEEDRRETFEMYVARADCSPDSG NKDSFVLKEGQFVEVLDSVHPDKWLVRTKPTKTNPARQGWVCPAYFEKKRKETFPQLRAP QEDLDGIGSTGEEYRRALSQLIQGMIDGEEEFVKEMKMFTSHQLNYLESSHPVPINILNQ KEIIFRNIKDIVSLHERLILPGLKECATDDDVAMHLIKHTEDFEKYLHYLVGQAQAEACV TDKAVQQYFKELLESGKSDAPAMDVLTFLQRPVERIQTYQALLKEFIKNKAKSGQSCCLL EDTFSMVSCLPWRSDNLHQVSLIENYPAPLIALGEPVRQGVFTVWEESPEIKTASRGHQR QVFLFKECIVLCKLKRDTNMNSDTFSFKNKMKLMDVEIKETLGGDEKSWGLWHEHRGSVR RYTLQGRSTLVKLSWLKDLKELQQRISLPTNSPPVFASLLCDCTTKIGQTIKLTCKVTGS PKPMISWLKDGLPLEDDPRHIITEDRSGTCCLILDSLTAEDSGQYACYATSCMGSAGTLA KVVVHASPRFVSRLESACLIEGEDIQFTCSTLTAPLPRIRWLKDGRELTDQQKYLIQNDA RSGILCLTVTRATEADIGQYECELWNEFGCVKCKAGLCPAYVPPIEDDQPQDLPPKDADS EGWSTAFVKKWLQTDFSPTSIAKMLFPPEHPEQAVVGGTEEAVPVSTSMEQVAQQPPCYP EEEEEIYISEQMQEITDAPPSIQVPAEDLCVEPGQRATFTAIVTGRPAPNIQWYKDGEEL AANENVEIAQHGARCSLTIVCPEGEDSGIYTCLAYSDSGHDSCHAELTVEEGPLECQERE VELGKRRKLFSVYDVHEEIGRGTFGVVKRVIHRRTGEVFAAKFLPLRSSIRTRAFQERDL LSRLAHPRVACLLDFFCTRRTLVLITEICCCHGLLDHLLLKGSVPEREVQSYIQQILEGV GHIHCMNILHLDIKPDNILMVYPPRDEIKICDFGFCQEIDTSRHQYSMFGTPEFIAPEIV HQEPVTVATDIWSVGVIAYLCLMCRCPFVGETDRATLLRVGEGTLNWDAPDVMRRSPEAQ NFLHMLLQPDPEKRPSAFECLSHEWLQDEHAGEDTDEINTKTLKIFISKRKWQRSLTCIG SVLTLRHIPELLDAPLRETAVTVPREPQEHSSTSPSSGSSSEYDEADSWDFFQHYSPTEE EEEETEEDYDPLMERAQIPDSFAKLRLDAEEEEEVTLGEEEDGEMVGRRSVLERSVSRQS VASSDVSSQQTPQRERRFSKDSNQSLYLSDGDEGSGSDGGRIPRGSVIRSTFYSTSHQLS PMSARHMTLRDKFQAKKQERGRKPLRRSFSGRLNEPLIEYVEDETETNRGQRRVSVQPTM QKSCSFDSGVSLAHTNAPPHRRSRSLDEYSRRSPSSPERTKSGEEEGSQSLKEDFTDDEV AGRNLLAIPSPRRPTRRGGSVSPTLPSGSSAPTNVLAGDRMSPRLDQEQAAGDTFAGSQG SLAESSILEHEGSELSSRPGSYEELSHGHLRGRYRSGESEGYDDQGEPLISPSPCSFQEV KPRSSFPQAPPRNRTRSNPNLSTNSRGQLGTPLTASPSPSLSSLQAPERPPRAKDKKGGG GLQRHASAPALEARPPTGRSPKLGLLRIFRRQSWTGHSYSQLDEAELGPTLGEIMKPDTP TMSLRKKMRASASSLTKLFSKSFSKEDVSKGGPIVKGAPPIPPERHRSSGLESPKKRTSK LLPSLKIPAFRKSKDLLVRPNKAEVFQLDGGGVLLVWKPVQSSDPVTYCVQYCTDGGEWT VLSEEVTDSSYVVKDLPRGASYVFRIGCITKTGAGPFSDASAPVVMATHPEETHIPLIQT ESLGSKVTGSEQQTAHKNFNFLSEINRGRFSVITLCRDVETSQVFAAKITPYQAEQRQLV LREYQLLKRLHHTHLVQLHAAFFTSRYLVLVEELCPGKELLHSLAMRDLYAECHVGELLV QILSAVDYLHSRRVIHLDLKSDNMLVDDCNHLKIVDLGSALSYTPGQPLIVEHIHGLSES KDRCSKVYIVLPKAPEILEGQGVGPETDIWAIGVLSFIMLSADSPFHAEHSWEQDKNIKK GKIQFGRCYPGLSEGALNFMKSSLNNKSWGRPTAAECLQNPWLRAHRAPHKARHSKVCFS TDKLKDYLKQKEEKRDQVSTKLQGPFFQ NT seq 19167 nt NT seq  +upstreamnt  +downstreamnt atgggtgacaacatacctggaggaatagtagctgctgcaaagaaccgtctgcaggtggtg aagggtttggaggatgtgcaggtgtctgagtgtgagagctgctcctttgacgtaaccttg aatctggcctatattgagggcgtgtggaccagagatgggctgcggctcaagtccaagccc acctgtcgcatcagcactcatgggaagaaacactccctcatactgagcagggtggctttg ggagacgcaggcctgttctcttttcaggcccccggcattcagacgtcagccagactcact gtcacagctagggacatccacatagtgacagagctggaggatgttgacacggtggagcgc caacctgtaaacttcgtctgtgaggtcaaccaagtggatttggagggtcggtggtacaga gatgacagccgaattcgacctggggacaacatcaagatcagacaccagggtaaaactcac accctgtgcttcaagtcagtcaggccagagcacgctggagagatcagattcactgcagag cgtgtctcatcttatgcaactctcacagtaaaagagctcccagtccaaatagtgcgtcct ctgagggtcaaaatagccatgtatcgccaccggggtctgctggagtgccaggtgtctcgg cctaatgctcaggtcacgtggtacaagaacaggaaggagctcgtgcccaataagaagtac cagatgatcagccaagatgtctacaggcagctgaccatcgatgacatctgctcctcagat gaggacacctacacctgtgatgcaggagatgacaacacctcctgtcagcttttggtggag gagcaggctatcagcatagtgcgggggatgagctcagtggaggtgacagagccagagcca gcgctgtttcaagtggagaccagcctgaaatcagggaggcccccccgctggaccctgaac ggtgaggtgctggagccttgcgcagcagtgaacatcgacaggcagggcaccctccacagc ctctgcttcacctacacagaaagctccatgtctggccctgtgctctttgtagctgggaag agtcgttccactgctcagcttactgtcaaagagcggcctcttcaagttgcccaccacttg gaaaatgcagaggcgaaggagaacagctctgtgactctgagctgtgcgtttgtgccctcg cccagagtggtgaggtggtttaaaggtcgtacggctctgaagaccaacaacaagtacagc atgaagagagaagggaaacgagcacagctgaccattcatggtttgtcagccatggatgca ggacagtatcgctgcatggctgggggtgcacagagcacagcacatgttaaggtagaagtg cggacgctgaagctggtaaaacacttagagccagtggaaattgaggaggatagcattgcc aggttcacgtgtgagctcaactacgtggttgccaatgtggagtggcttctcaacaatgtt cgcctctattgcaatgccatcaacaggatccagcacatgggcactatgcacagcctcaca attaagaatccgcgaccacaggagagcagggtcaccttcaaagccggccttctctctgag acaaccatcttaaaagtcaaagagcatccagcagtgttcctgaggtctctggaggatgta gtgggagaagagcaaggggaggtctgcctgcagtgtgagatttccaaagagaaagtgacc cctgtttggaggaaggatggcgagatcctgaccactgatgataaacatgagttactccag tctgggaagtccatggcactgatcatccattccctgagcaaagatgatgctggacattac acctgtgacctgggcaccagccagaccaaggctaaagttactgtgcatgacttacgcatc actattgttcatcgtataaagataacatcagtccaagaaggcgaatgctgcacttttgat tgtcaactctctcacgatctcgatgacgagccttcctggaccatcaatggccagctggtt gtcaccaatagccgtatccaggttatcaacaatggccgccactataagatgaccattaga gatgctttactgactgacgctggagatgtggtcttcacaattaaagacctaagctgtagg accatgctctttgttaaagagaagccggtgcacatcttcagggagctgctgaacactaag gcagtgccaggcgaagacgcagagctgagctgtgagatcaccaaaccagaggtcctgatc cgttggctgaaaaatggccgtttgatcaggccgagccccaagtatgtgatgagtgtagag aagaacctggcgcgactggtgatcaagaattccaccatcagagactctggagagtactgc tgtgaggccgatggcattgcctcgcgtgccaagctggagatcagagagctccagcacaca tttgcgagggagttaagggacacgcgggcagaggaaaagggtaaagtgaccctggagtgt gagaccaggcggccagccaagcgagtgacctggctgaagggcatggtggagctgaggtcc ggtaggaagtatgtcatcaggcagaagggtgtggtgctgtccctgaccatcacctgtctg gacaagtcggacacagatatttacatttgtgatgtcggtaccatgcagagccgggcacag ctgacggtgcagggtcagagggttttgatcctggatgaattagaggatgtcgagtgtcta gagggcgacacggtcacattcaagtgtcgaatttgtcccagtgactacattggggtaaaa tggtatctggacgagactttgctgtacacaaatgagctcaatgagatccagatggtggcc ggaggctaccacaccctcacatttagacaactcgcccgcaaagacactggcactatctca ttttcagcgggggacaaaagatcgtacgcctcactgttggttagagagaggcgtcccacc atcattaaagcactggaagactgcgaggctattgaagggggtggtttggttttgtcttgc gtggcctccaagccatgtcacatcctgtggtacaaagatggctgcttgatgtggaactcc tcgaggtattttgccagtcgttccggctgtgaggcccggctgacgattcgggaggtcagc aacaacgatgctggagtgtatgagtgcagtgctggatctgttaccacgagggccgttgtg actgtcagagccatcccagcagagttcatccaggctcttaagtccttggaggccaaagag ggggagaccgtcaccctgacctgtgaatactctctgcctggggtccagtgccactggaag agaggtttcgagagtatcaggcctggagacagatacctgattaaacagaggaagacgatc aattctctgaccatcaaagcactgaagcctcttgactcaggagaatatacctgccagtgc agagatcaccacactacagcaagcctcaaagtacacgctattcccataacatttatacag aagttaaagaacatgcaagcagaggagggaagcaatgtcctactgcgctgtgagctgtct aaacctggaattccagctgaatggaggaaggaacatgagctgttgaagaatggagtgaaa taccagataaggaaaagagagaccactctggagcttctgatctggaagcctgttccagag gacagtggggtctacagctgtgcctgtgctgatcagataacatctgccactgtcaaaatc actgctctcccagtcaccttcaagcagaagctgaggaatgtgctcattgaggaaggcagc actgcggctctacgctgcgagctgtcgaagcctgggtacagtgtggagtggaggaagagc ggggatgaactcatcaggaatggagagaaatatcacatacgacaaagagacgggctgatt gaactgaggatccttgatgttagacctgaggacagcgacatctacacatgcatctgtgga gacatagagaccactgcaactctgactgttaatgctcttcccatcaccttcaagcaaaag ctgaagaatgtccaagtggaggaaggacacaacatcacactgtactgtgagatctctaaa gcgggtgtccctgtggagtggaggcttggaggagatctgctggagaatggagagaaatac cagattaagcaaagggcctcagccctggagttgatcatcagagatgctgaaccagacgac agcggggtctacacctgtgtgtgtagagagcagaagacaaaggccactgttaaagttatc gctgttcccaccacatttaaagttagcctgaagggccaggaggctgaagaagggaagagt gtgactttacgctgtgagctgtcaaagaagggagtccaggtgcagtggcagagagacgct caggtgctgtctgagtttacgtaccgagggaagtatctgatcaaactagaaggaaagaca gctgagatgaccattgtcaacgtccaacctgaggatgctgggaagtacagctgcatcaca ggagatgagaaaaccacagccgaagttaaagtgaaaccacttcctgtgacattcaaacga gagatccagcgcatggtggtgaaggaaggggacagtggcgttttcagctgcgagatctcc aaacctggagctcctgtggagtggaggaaaggcaggacgatcctgaagcctggaaacaaa tacgagatgaagctggagggacctttcgctaaacttgtcatcaacgacgtggaggagagt gatggtggcaaatatacctgcaagaccaaagacagccaatcaactgctgagctcattgtc caagatttgccagcaagtttcaagatgccactagttaaccaggaggcaacggagggcaac agtgtggttctgcgctgtgagctcaacaaacctgccccttcggttgagtggaggagagga tcagagctgctgaaaaatggagacaaataccagatgaggaagaaggacctgcaggtggag atgaagattactgagctcagtctggacgatgctggagattatacctgtatatgtggagaa cacagtacacaagctaggatcactgtgaatgagcggcccatcaaattccttcaagaactg aagaatattcaggtccaagagggcaacggagtgacactctgctgtgagctctccaaacct gacactccagtgcagtggaagaagggagacaaagtgttgaccaacggagagaaataccag atgaagcagagcggctccaaggtggagctcctcatcaggaaaagccagcctgaggacagt ggctcatacagctgtgtatgtgaggacgtaaaaactactgccaccatcatcatcactggg atcccaataactttcaagcaaaagttgaggaaccaggaagctgtggaggaaggcaacgtg acgctgcgctgtgagctttctaaagcaggagtcccagtggagtggaggaaagatgctcaa cttctgatggagggagaaaaatatcagatgaagcaagaaggcaggacagctgagatgctg atcagaaatttaactcttaaagatttgggggagtacagctgttttgttggcactgttgtg acttcagctgacatcaaagtaagagcacttcctgttatatttaaacaagagctggagaaa ttggaggtgaaggaaggggacagtggagttttctcctgcgagctctccaaacctggagct ccagtggactggaggaaaggcagagtcatcctcaaacctggatacaaatatgagatgaaa caggagggacgtttcactaaactgatcatcaacaacgtagaggagagtgacgcagggaaa tacacctgcaagacgaatgacacccagtcaaccgctgagctcatcgtcaaagctcctccc atcacattcaagacaaagttaaggaaccagcaggtggaggaggagaacagtgtgacgttg aactgtgagctgtctaaacccggcctccctgtggagtggaggaaaggacaagagctgctg aagagtaatttcaaataccagattaaaaatcgaaacagcaacatggagctcaccatcaag aacgcacagctggaggacagcggactgtacagctgtatctacggtgacaccaaaacaaca gccaacatcaccattacacctatccccctcacctttaaaatgggtctgaagaaccaggag gcccctgagggaggcaatgtgtcccttcactgcgagctgtccagggccggggtgcccgtg cagtggtggaagggggaggaccagatctatcaggggggacggtatcagatgacgctgaag gggaaaacagctgagatgaacataagaaacatccagcctgaggatgtcggggagtacagc tgcatcgtgggagagcagaagacgacggctgaggtcaacgtcagagcggcagcatctgtg ttctttgagaaggaactggaaagccaagcggtgatggagggcaaatctgtgctgctgtcg tgtgaagtctccagtgctaatgtccctgtcacctggaagaaggacaacactgtgattgaa gaaggagggcggtacattttaaagaagaaaggcccaacacacagcctggagatcaagaaa ctgcacctggaggatgctggagagtactgctgtatcaccagaggcaagaagaccacggcc aagctgatcgtgagggcttcctcttcctccacagagcgcgtgcggatcgttacagagcta cagggtataacggtgacagcgggtgaggacgcggtgtttgtgtgtgaactgagccacgca gacgtgagtgagggtgtttggtggcttggctccagccctctgcagaagaacgagatgaac cagatgatgtgccacggtcgcgaacagcggctggtcctcaccatgacaacacctgaggag accggcatcgtggcatttgtgattggggaggagaggacctctgcacgtctgctagttgtt cctaaggccagagttttatttgaggagaagcctaaagacgttgtgatcatggaaggagag acagccactctgtcctgcacaatctctgattttacctccctggttacctggaggcgcaac cacatccccctccgaaatggtgataaatatgagatacgtaaggagggaaaagtcaaccta ttgctaatacatgatgtggatcccttggatactggcacatactgctgtgatacaggagac gtgcagagcagtgccaaacttactgtaacagagctccctccattcttccaagaagaactg caaagcgtggaagttgaggagggaggttcagctgctctgtactgtgagctgtctaaactt ggagtgccgattcaatggaagaagaaagggctgccactaagagccagccaaaagtacgag atcaggcaagatggctgtctcctccagctgcacatcaaggatctcaaacttgaggacagc ggcagctactcgtgtcaagcagggagtgcagagaccactgctactgtgacagtgaaagag ctcccaccattcttcaagaaagaattacgaagtgtggaggctgaggagggaggtacagcc tctctgtgctgtgagctgtctaaagctggagtgtcggtgcaatggaagaagaacagacta cctctaaaagccagcagaaagtatgagataaaacaagatggctgcctcctgcagctccac atcaacgagctcaaacctgaggacagggggagctacacatgtcaagcaggaagtgcggag accactgcaactgtgtcagtgaaagagctcccaccatttttcaaagaagaactgcaaagc gtgaaagttaatgaaggaggtacagcctccctgtgttgtgaggtgtctaagcctggagtg tcagtgcaatggaagaagatcaagctgccacttagagccagtaggaagtatgagatgaag caagatggctgcctcctccagctgcacatcaaggagctccagcctgaggacagtggcagc tacacatgtcaagcaggacatgtagagaccactgctactgtgacagtgaaagaagtccca ccatttttcaaagaagaattgcagaatgtgaaggtggaggagggagcaacaacctctctt tgctgtgagctgtctaagcctggagtgtcagtacaatggaagaagaacaggctgccactc agagcgagcaggaattatgagatgaaacaagatggctgcctcctccagctgtacatcaag gatctcaaacctgaggacagtggcagctactcgtgtcaagcaggaagtgctgagaccact gcaactgtgacagtgaaagagcttcctccattcttcaaggaagacttggaaagtctggag gttgatgagggaggtacagccaccctgtgctgtgagctgtctaagcctggagtgtcagta caatggagtaagaacaggctgccactgagagctaacaggaagtatgagatgaagcaagat ggctgcctcctccagctgcacatcaaggatctcaaaccagaggacagcggcagctactcg tgtcaagcaggaagtgcggagaccactgcaacagtgacagtgaaagaactcgtaccattc ttcaaggaagacctactaagtgtggaggctgtggagggaggttcagcctctctgtgctgt gagctttctaagcctggactgtcagttcaatggagtaagaacaaactgccactgagagct aacaggaagtatgagatgaagcaagatggctgcctccttcagctgcacatcaaggatctc aaaccagaggacagtggctgctactcgtgtgaagcaggaagagcagagaccactgcaact gtgacagtgaaagagcttgcaccattcttcaaggaggacttagtaagtgtggaggccgag gagggaggttcagcctctctgtgctgcgagctgtctaaagctggagtgttcgtgcaatgg agtaagaacaagctaccactgagagctaacagtaagtatgagatgaagcaagatggctgc 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gcttctctgtgctgtgagctgtctaagcctggagtgtcagtgcaatggaagaagaacggg attccactaaaagcaggcaacaagtacgagataaagcagggtggctgcctgcttcagctc tacatcaaggatctcaaagtggaggacagcggcagctacacatgtcaggctggaagtgca gagaccactgctactgtgacagtgaaagcactagaaccagctccaccaaaggcagagcct cccacgattctgcctcgggcaaagggccccgtctccaaaccaactcctgcgccagaaagc cagaagcctggactcccagaagccaaacctgttcctccagagcccaaaaagagagctcac aggaaagcatcaattgcaagtttagaaaaagatgtggagccaatgtttgacctaaaacag ggcatccaacctgcgagatctatggagaaagaccttgatgttgcacagaacataatacaa ctggaaaggcatgtggagaaagacaatgagttgaacaagaaagttgacaagacagtgaga ccactggagaaagataatagggttgacagggaggtggaagagccagcaagacctttggaa acagagaaagatgttctcatggagaggagacaaccaggaaggattacagagaaattagtc caggttgaccataatgcaagtgaaacagacaaagttgttggagacactgtgtttgaacaa aagaaaaggaaggatgaagttgaacagatattaaaacaagcagtgaaaccttcagagaga acaagtgaagttgagaggaatgaaagccatccagaaaaagtccagtgggagaagagtgag gatgaaaaaccgtctgtgaaaccattagaaaagtttatcgggagtaaaacaataaaggac caagaagagaagtttatagtaaaggaaggcaaagtagaggaagaagaaccttttaaacca 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gcagatcttcatggtacaataacactagtgtgtgttgttgaaggaaaacccagctcagtg cgctggctgaaaaacggccaacaaatcacaaatgactatcgatgccgtatcgagactaca gagaacggcatgtgcacactggtgatcaaaaacctgaccaccagtgacagtggaatctat acctgcgaggtggtgaataagtttggtgttacctcctacaatggaaacataacagtagta cagcctcagaagcctgctccagtggtccagaagcctatacacccacctcttgctgccatt actcctctgcaactcgccccacaaaagcctgaggaagaaacacagacccaggatctgcct cagactcaaacccagacacctccttcagctgcagatgctgagaactatgtagaaaatgtg agtgtctctctatgggaggcctacaacctgacggagcaggacgctcaggcgaggctgcaa gagaggagagggtcttcactcattgctgccagctccatgtcgagtccctcggattatgaa acagctcctgacattatggaacctgttgagactggtccaactgtacaactgagggtagag acaaaagcagtggaccaagttcctccagaagatgaagaacaacctccacagccaactaag acactactgaaggtcaaagcagctcatgaaggtaaaatgaggacaccatctcccaagcac caccacgctcacacacccttaacgagtaccgtctctggatcagagtcagagggagaggag gatagacgagagacatttgaaatgtatgtggctcgagctgattgcagtccggacagcgga aacaaggacagttttgttctgaaggagggccagtttgtagaggtcctggactcggttcat cctgacaaatggctggtgaggaccaaacccaccaaaaccaaccctgctcgacagggatgg gtgtgtccagcctactttgagaagaagaggaaggagaccttccctcaactgagagcacct caagaggatcttgatggcattgggtctacaggagaagaatacaggagagctctgagccaa ctgatccaaggcatgattgatggagaggaggagtttgtaaaggagatgaagatgttcacc tctcaccagctgaattatttggagtctagccaccctgtccccatcaacatcctcaaccag aaggagatcattttcaggaatatcaaggacattgtgtctctgcatgagaggttgatcctt cccgggctgaaagagtgtgcaacagacgacgatgtggctatgcatctgatcaagcacact gaggactttgagaagtatcttcactacttggtgggacaagcacaagcagaggcctgcgtc actgacaaggctgtccagcagtatttcaaagagttactagagtctggtaaatctgatgct cctgccatggatgtccttactttcctccagcgcccagtggagagaattcaaacctaccag gctttactgaaggagttcatcaagaacaaagccaaaagtggacagagctgctgtcttttg gaggataccttctccatggtgtcctgtctaccctggaggtctgacaacctgcaccaggtg tccctcatcgagaattatccagctcctctgattgccctgggtgaaccagtgcgacaggga gtcttcacagtctgggaggaatcgccagaaattaaaacggcctctagagggcatcagaga caagtctttctcttcaaggaatgtattgtactgtgtaaactgaaaagagacaccaatatg aacagtgacaccttcagcttcaagaacaaaatgaagctgatggatgtggaaataaaggag actctgggtggagatgagaagtcttgggggttgtggcatgagcacaggggctcagtacgg aggtacacactgcagggacgctccaccctggtgaaactgtcctggctcaaggatctgaag gagctacagcaacgtatcagcctgcccaccaacagcccaccggtgtttgcgtcactgttg tgtgactgcacaacaaagattggacagacgatcaaattgacctgtaaggtcacaggatca ccaaaaccaatgatcagctggctcaaagacggccttcctttagaagacgatcctcgtcac atcatcacagaggaccggtcaggcacctgctgtctcatcctagacagcctcactgcagag gactctggacagtatgcttgttatgctaccagctgtatgggcagtgctggtactctggcg aaggttgtggtgcacgcttcgcccagatttgtgagtcggctggagagtgcctgtctgata gaaggcgaggatatacagttcacctgctccacacttactgctcctttaccacgtatcagg tggttgaaagatggcagagagctgactgaccagcagaaatacctaatccaaaatgatgct cggagtggcatcttgtgtctgacggtcaccagggcaacagaggcagatattggacagtat gagtgtgagctttggaatgagtttggctgcgtcaagtgcaaggccgggctgtgccctgct tacgtgccaccaatcgaagacgaccagccacaggacttacctcctaaagatgcagactca gagggctggtccactgcctttgtgaagaaatggctacagactgatttcagccccacctct attgctaagatgctcttcccccctgaacaccctgaacaagctgtagtgggtggtactgaa gaagccgttcctgtctcgacatccatggagcaggtggcacagcagcctccgtgctaccca gaggaagaggaggagatctacatctcagagcaaatgcaggaaattacagatgctcctcca tccatccaggtacctgctgaggacctgtgtgtagagcccggccaacgagctacatttacc gccatcgtcacaggacgacctgctcccaacatacagtggtataaggatggagaggagctt gcagccaatgagaatgtggagattgcgcagcatggtgcccgctgttcactgacaatagtg tgcccagagggtgaggacagcggcatatacacctgtttagcctacagcgactctggccat gactcatgccacgctgagctgacagtggaggaaggtcctctggagtgtcaggagagagag gtggagctggggaagagaaggaagttattctccgtctatgatgtccatgaggaaattgga aggggaaccttcggggtggtgaagcgtgtaatccacagacgaacaggtgaagtgtttgct gccaagtttctgcctctgcggagcagcattcggaccagggccttccaggagagggacctg ctgtcccgtctggctcaccccagagtagcttgtttgctggactttttttgtaccagacgc actctggtgctgatcacagagatctgctgttgtcatggacttctggaccatttattactg aaaggatccgtcccagagagagaggttcagtcatacatccagcagatccttgaaggagtc ggtcacattcactgcatgaacattctgcatctggacattaaacctgataatatcctgatg gtgtatccacccagagatgagatcaagatctgtgactttggcttctgccaagaaatagac acatctagacaccagtacagcatgttcggtacaccagagtttattgcccctgaaatcgtt caccaagaaccagtcactgtggccactgatatttggtctgtaggtgttatagcctattta tgtctcatgtgccgatgcccttttgtgggagagacggaccgtgctacactgctgagggtg ggagaggggaccctgaactgggatgcccctgatgtgatgcgcaggagccctgaggcccag aactttctccacatgctcctgcagccagatccagagaaacgaccatctgcctttgagtgc ttgagccatgaatggctccaggacgaacatgcaggagaagatactgatgaaatcaacaca aagactttgaaaatcttcatctcgaaaaggaaatggcagcgctctttgacctgcattggg tcagtcctcacattgaggcatatccctgagctgctggacgctcctctcagagaaaccgca gtgacggtgccccgcgagcctcaggaacacagcagcacctctccgagcagtggctcctcg tctgagtatgacgaagctgactcttgggactttttccagcactacagcccgactgaggag gaggaggaggaaaccgaggaggactatgatcctttaatggagagagcgcagatccctgac tctttcgccaaactccgcctggatgcagaggaggaggaggaagtgacattaggggaggaa gaggatggagagatggtaggaagaaggagtgtactagagcggagtgtgagcaggcagtca gttgcgtcatcggatgtgtcgtcccaacagactcctcagagggagcgaaggttcagcaag gacagtaatcaatctctctacctgtctgatggggacgagggttcagggagtgatggaggt cgtattcctcgtggcagcgtcatccgaagcactttctacagcacctcccatcagctttca cccatgtctgccagacacatgacattacgggacaaattccaggccaaaaagcaggagaga ggccgcaaaccactccgcagaagcttttcaggacgtctcaatgagcctcttattgaatat gtggaggatgagacggagacaaatcgtggccagagacgagtatctgtccagcccacgatg cagaagtcctgctcctttgacagtggtgttagcctcgcccacaccaatgccccccctcac aggaggagcaggtctcttgatgagtattctagacgatctcccagctcacccgagcgcaca aagtcaggggaagaagaaggctctcaaagtctgaaggaagatttcacagacgatgaagtg gctggaagaaacctgttggccatcccgagccctcggcgacccacaagaagaggaggttcc gtctctccaacactgccgagtggatcttctgctcccacaaacgtccttgctggagacaga atgagccccaggctggatcaggagcaggcagcgggtgacacctttgctggctcccagggg tctctggctgagtcgtctattttggagcatgagggctctgagttgtcaagtcgacctggc tcctacgaggagctgagtcatggccatctcagagggagatacagatcaggagagagtgaa gggtatgatgatcagggggagcctctgatttcaccatccccatgttcattccaagaagtc aaacccagaagctcatttccccaagcaccgccgcgtaaccgcacccgctccaaccccaac ctgtccaccaacagcagaggtcagctggggaccccactaacagcgagccccagtcccagc ctctcctctctgcaagctccagagaggcctcccagagccaaggacaagaagggcggtggt ggcctccagaggcacgcatcagctccagccctcgaagctcggccacccacaggaaggtca cccaagctgggactgctgaggatcttccgcaggcagtcctggaccggccactcgtactcc cagctggacgaggcagagttaggacccacactgggggagatcatgaagccagatactccc accatgtctctgaggaagaaaatgagagcttcagcctccagcctgaccaagctgttctca aagtcttttagtaaggaggacgtgagtaaaggagggccaatagtaaagggagcacctccc atcccacctgaaaggcatcgcagcagtggtcttgagagcccaaaaaagaggacgtccaaa ctgttgccttctcttaaaatacctgcgttcagaaagtcaaaagatctgctagttcgtccc aacaaggctgaagttttccagttagatggaggtggagtcctactggtttggaaaccagtc cagtccagtgaccctgtcacctattgtgtgcagtactgtacagatggtggggagtggacg gtcctgtcagaggaggtgactgacagcagctatgtggtgaaggacttacccagaggagct tcttatgtgttcaggatcggctgcatcactaagacaggagcaggacctttcagtgatgct tcagcacctgttgttatggctactcatcctgaggagactcacattcctctgatccagact gagtcactggggtcaaaggtcactgggtcagaacaacagacagctcataagaacttcaat ttcctctctgagatcaacaggggtcgtttcagcgtaattaccctgtgcagggatgttgag accagccaggtgtttgctgccaagatcaccccttaccaggcagagcagagacagttggtg ctgagggaataccagctgctgaagaggcttcatcacactcacctggtgcagctgcacgct gcctttttcacctcccgctacctggtgttggtggaggagctctgtcccggcaaggagctg ctccatagtctggcaatgagggatctgtacgcagagtgtcatgttggcgagctgctggtt cagattctgagcgcagtcgactacctccacagccgtcgagtcatccacctggacctgaag tctgacaacatgctggtggatgactgtaaccacctgaagatagttgacttgggctcggct ctgtcctacacacccggtcagcctctcatcgtcgagcacatccacggcctgtcagagagc aaagaccgctgcagcaaagtttatattgtccttcctaaagctccggaaatcctggaaggt caaggtgtcgggcctgaaactgatatctgggctattggagttctgtcctttatcatgttg agtgctgacagcccgttccatgcagagcacagctgggagcaggacaaaaacatcaagaaa gggaagatccagtttggacgctgttaccctggtctgtcagagggagccttgaacttcatg aagagcagcctgaataacaaatcctggggaagacccactgcggccgagtgtctccagaac ccatggctgcgtgcccatcgtgccccacacaaagcccggcactccaaagtgtgtttctct acagacaagctcaaagattacctcaaacagaaggaggagaaacgagaccaggtcagcact aagcttcagggtcccttcttccagtaa

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