Epinephelus lanceolatus (giant grouper): 117258233
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Entry
117258233 CDS
T07331
Symbol
raf1a
Name
(RefSeq) raf-1 proto-oncogene, serine/threonine kinase a isoform X1
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
ely
Epinephelus lanceolatus (giant grouper)
Pathway
ely04010
MAPK signaling pathway
ely04012
ErbB signaling pathway
ely04068
FoxO signaling pathway
ely04140
Autophagy - animal
ely04150
mTOR signaling pathway
ely04210
Apoptosis
ely04218
Cellular senescence
ely04270
Vascular smooth muscle contraction
ely04370
VEGF signaling pathway
ely04371
Apelin signaling pathway
ely04510
Focal adhesion
ely04540
Gap junction
ely04625
C-type lectin receptor signaling pathway
ely04810
Regulation of actin cytoskeleton
ely04910
Insulin signaling pathway
ely04912
GnRH signaling pathway
ely04914
Progesterone-mediated oocyte maturation
ely04916
Melanogenesis
ely05132
Salmonella infection
Brite
KEGG Orthology (KO) [BR:
ely00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
117258233 (raf1a)
04012 ErbB signaling pathway
117258233 (raf1a)
04370 VEGF signaling pathway
117258233 (raf1a)
04371 Apelin signaling pathway
117258233 (raf1a)
04068 FoxO signaling pathway
117258233 (raf1a)
04150 mTOR signaling pathway
117258233 (raf1a)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
117258233 (raf1a)
09143 Cell growth and death
04210 Apoptosis
117258233 (raf1a)
04218 Cellular senescence
117258233 (raf1a)
09144 Cellular community - eukaryotes
04510 Focal adhesion
117258233 (raf1a)
04540 Gap junction
117258233 (raf1a)
09142 Cell motility
04810 Regulation of actin cytoskeleton
117258233 (raf1a)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
117258233 (raf1a)
09152 Endocrine system
04910 Insulin signaling pathway
117258233 (raf1a)
04912 GnRH signaling pathway
117258233 (raf1a)
04914 Progesterone-mediated oocyte maturation
117258233 (raf1a)
04916 Melanogenesis
117258233 (raf1a)
09153 Circulatory system
04270 Vascular smooth muscle contraction
117258233 (raf1a)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
117258233 (raf1a)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ely01001
]
117258233 (raf1a)
Enzymes [BR:
ely01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
117258233 (raf1a)
Protein kinases [BR:
ely01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
117258233 (raf1a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
Pkinase_fungal
C1_2
Motif
Other DBs
NCBI-GeneID:
117258233
NCBI-ProteinID:
XP_033484792
LinkDB
All DBs
Position
8:18351079..18370018
Genome browser
AA seq
677 aa
AA seq
DB search
MEHLQGAWKTLSNGFGMKDSAFEGPCLSPTMVQGFPCQRRSSDDSKMPDSKTSSTIRVYL
PNQQRTVVNVRPGMTLHNCLIKALKVRGLQPQCCAVFRLHPGQRSKKFRMDWNTDSTSLI
GEELLVEVLDHVPLTTHNFVRKTYLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPT
MCVDWSNIRQLLLCPTPGESGAPSLPPLTSRRMRESLTRFPSSAHRYSTPHAFNYTAPYT
PTGGGLSQRQRSTSTPNVHMVSTTLPVDSSMIELDCLNTSPSSWCHRFWLKRKVGIVHFP
QSFVEASSESPEKDAMRDHDSAGSSPNQSPTGWTQHQPKAPAPAQRERAPSFNTQEKNKI
RPRDKRDSSYYWEIEASEVYLNSRIGSGSFGTVYKGKWHGDVAVKILKVTDPTPEQFQAF
RNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHIHVLETNFKIIQLIDIAR
QTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKARWSGSHQVEQPSGSIL
WMAPEVIRMQDNNPYSFQSDVYSYGIVLFELMTGELPYSQIATRDQIIFMVGRGYLSPDL
SKLYKNCPKAMKRLVADCIKKSKDERPLFPQILSSIELLQHALPKINRSASEPSLHRASH
TEDINACTLTSTRLPVF
NT seq
2034 nt
NT seq
+upstream
nt +downstream
nt
atggagcacctccagggagcgtggaagaccctgagcaacggcttcggaatgaaggactcc
gcgttcgagggcccgtgcctctccccgactatggtccaaggcttcccctgccagcgtcgc
tcctcagatgacagcaagatgcctgactccaagactagcagcactattcgtgtctacctc
ccgaaccagcagcgcactgtggtgaacgtgcgaccaggtatgactctgcacaattgcctg
attaaagcgttaaaggtgcgaggtctgcagcctcagtgctgcgctgtcttccggctgcac
ccaggacagaggagtaaaaaatttcggatggattggaacactgactccacctccctgatt
ggagaagagctactggttgaggttttagatcacgttcccttgacgacgcataattttgtc
cggaaaacatatctgaaactagcgttctgcgatatttgccagaagtttcttttgaatggt
ttccgttgccaaacttgcggctacaaattccatgagcattgtagcaccaaagtgcccaca
atgtgtgtggactggagcaatatcagacaactgctgttgtgtccaacacctggtgagagc
ggtgccccgtcactgcccccgctgacgtcccggcgaatgagagaatctttaacacggttt
ccaagctcagcccaccgatattccaccccccatgccttcaactacaccgcgccttacacg
cccacaggcggcgggctctcccagaggcagcgctccacttccacgcccaacgtccacatg
gttagcactaccctgcctgtagacagcagcatgatcgagctagactgcctgaatacgtcc
ccaagctcctggtgccatagattctggctgaagaggaaagtaggtattgtgcacttcccc
cagtcttttgttgaagcctcatccgagagtccagaaaaggatgcaatgcgtgatcatgac
tcggcggggagttcccccaatcagagccctactggctggacccagcaccagcccaaagcc
cctgcacctgcccagcgagagagggccccgtccttcaacactcaggagaaaaataaaatt
aggccccgggacaagcgggactcgagttactactgggagatcgaggccagcgaggtgtat
ctcaactcccgcatcggttcaggctcatttggaaccgtgtacaaagggaaatggcatggt
gatgtagcagtgaagattttaaaggtgaccgaccccacaccagagcagttccaggctttc
agaaatgaagtggcagtcctgaggaagacacgacatgtcaacatcctgttgttcatgggc
tacatgacgaaggacaacctggccattgtgacccagtggtgtgagggcagcagcctctac
aagcacattcacgtcctggagacaaactttaagataatccagctcatagacatcgccagg
cagacagcacagggcatggactatctgcatgcaaagaacatcatccatcgtgacatgaag
tccaacaacatctttttgcatgaaggactaacagtaaaaattggagactttggtctggca
acagtgaaggccagatggagcggctcacatcaggtggagcagccttctggatccattctc
tggatggctcctgaggttatccggatgcaggataacaacccgtacagtttccagtctgac
gtctattcctatggaattgttctctttgagctcatgacgggagagctcccatactcccag
atagcaactagagatcagataatcttcatggtgggaagaggctatttgtccccagacctc
agtaagctctacaagaactgccccaaagccatgaaaaggttggtggctgactgcatcaag
aagtccaaggatgagaggccgctcttcccgcagatcttgtcctcgattgagcttctccag
catgccctacctaagataaaccgcagtgcctcagaaccgtccctgcacagagcctctcac
actgaggatatcaatgcctgtactctgacctccaccagactgcctgttttctag
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