Epinephelus lanceolatus (giant grouper): 117259595
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Entry
117259595 CDS
T07331
Symbol
brca2
Name
(RefSeq) breast cancer type 2 susceptibility protein isoform X1
KO
K08775
breast cancer 2 susceptibility protein
Organism
ely
Epinephelus lanceolatus (giant grouper)
Pathway
ely03440
Homologous recombination
ely03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
ely00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
117259595 (brca2)
03460 Fanconi anemia pathway
117259595 (brca2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
ely04121
]
117259595 (brca2)
03036 Chromosome and associated proteins [BR:
ely03036
]
117259595 (brca2)
03400 DNA repair and recombination proteins [BR:
ely03400
]
117259595 (brca2)
Ubiquitin system [BR:
ely04121
]
Ubiquitin ligases (E3)
Multi subunit type E3
BRCC complex
117259595 (brca2)
Chromosome and associated proteins [BR:
ely03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Other centrosome duplication proteins
117259595 (brca2)
DNA repair and recombination proteins [BR:
ely03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA complex
117259595 (brca2)
FA (Fanconi anemia) pathway
Downstream FA components
117259595 (brca2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCA-2_helical
BRCA2
BRCA-2_OB3
BRCA-2_OB1
BRCA2DBD_OB2
Tower
BRCA2_TR2
Motif
Other DBs
NCBI-GeneID:
117259595
NCBI-ProteinID:
XP_033486911
LinkDB
All DBs
Position
9:15166244..15183783
Genome browser
AA seq
3042 aa
AA seq
DB search
MNFPSKNMYDTYKDEIWKELGPLDPNWFEALTAQTFTNEGNVSDQDDLCANQEGNFKTPL
DKAAVDSQLFSTPKVFRKSRVVSPETEDEHSFTAEQEKETLTWMATQSPCMFRVSKMGVP
GEKYGGFQPQSQSSFDLLHTPQKSPVSHAKHISESLGAQIHPDMSWTSSLNTPPAVPSTL
ILSKTDESPCPVRVSPDKNVVIVRKLFPSLSNASRIEVVSPKNNDIPTIHQGVVSPEASQ
NPETHNSPQSSLNQSDGVWKQKLPDAVEDGEICRTGPGVLDGAENVLSPFFTNSSSALRK
VKTDRVKRKQIIPTKEDADNNANGAASSEQRTDDQEPGRLPSSPQVKTGDIEITQWSPLS
LSEIPPCTVDSACYDSSPAQVENKMLTEQLQSDSVFSLPVRPPMKTPDSGWTKKKRKFVY
TVKTPEVQGKEAQSQRMDSSPGQEVHVKQSGKAQDEADSCSIGKKEMQKQGNVAEESLPP
FVQGKVQDLDMSQLCRDFAQDFSQMLDPSKPSKEAEYTPQDGFSPSACLSAVKQAKQKAV
QANLYHDCDGVSNRKHVSTTNPKNSISEGTVSDSGFQSAVADSTHVTASSFVLPSSEING
ESQQWTGFKTDMHRTTPFASSSKGNGKEHLDDISQGAETDAKLPSTIRGSQTLGLGRESE
LPIESTSAQLPSSTKGTVDNINCVPLNGQAHGSLPQKTTVSLPSVHTSGFKTASNKGIHI
SSANLKKAKRLFEEIEGERTVSEQPTICDHGTKEEISVSCESVKNPTTMSNQPLCSSEKN
VDISCHLTASQKADVTEICTLLEEADTQFEFTQFKTANLKQHSQDNATSPQKVDKELDPD
FLSGIDFDDSFSAEAEKHVAVTVSQDKITLASDGKTNCETSNVTSKSTGLSLSSAMKIEN
PSTEAVSSSSKQISEGSSRIMSAEPKNLDSTGHPETSKLENKNPVMLGVGFKTAGGNILR
VSKTCLSKARALFADLEDNLVTSQKSLDKQCSKTNAETQHKHSGDNHTGNVLLHKDDKSE
FIGNDTGGSIQGCFSKMKEYVSSYKQVTSIRDDVTGNLKNSKLDTTTCQSGFLMASGRNI
SISAKAMQEADAFFKDCDSMDTNTGMPVKHKKSMEPLPGSLSHKETLPKCKNVQGINVKV
SEEPINEFENGNAGPTARHTEVVQHNVEVPNFGFKNTPMLTNAVPSLTAKALSSLSCTTS
KNFGSSSGGFSTASGKKVSLSADAMKKAECLLNEIHTLEDTNQQLKQKGDAFRSSHLTSQ
IQIPPKNVGFQTASGKGFAISSAALKKAKLLLSECDVVEDEIGAKPTHSKMPVPPLPPKN
SGFLAASGKPVTFSSEALQKAKTLFTDISLSTEIPAASGSKTTDRKKANSENTEKIHCGF
TTAGGAKVHVSQKNLLKARNLLKEFDDGCISAKAMQETDVFFEDCDINDAISVKHKSVTP
VSGSGSEKKKPSEFKQDQRVTNIYREPGSGHTDFENVNVGPVVNHEKMLHPNAVENDKGV
LKGTLDSFKAASLHGNPSMAKPRSPVLCTTSKNISSSAINESSNIGRFCTAGGKKVTVSD
DAMTKAKSLLNKSATFEDTNKQLKQKEDTFPQNNGGFQTASGKGVAISSAALKKARILLS
ECEGADDEIGVKPTHSKTPVATSVPPKNRGFLAASGKPVAFSSEALQKAEALFSDISFST
EIPAMSDTRNTDKKHSNSEITEKMHCGFTTAGGAKVHVSQKNLLKARNLLKEFSDGQCHV
SNASSRGPDDTNKSDLSKVKDVNKASNSNLSIPCDKEIPSKFSAPQVVKPLQDTDHEKET
LQTPSVPGGVLAKDKALPDSYKSKRDKMTPSGSCISNSPGEGMSSLLDYEKNQTSSSDES
KVKRPQDSSVLNFQAFNLSGCTETQQMFFAQEALDCTKALLEDESLAGQSLSMTLETVPL
QDNPRSSCKSVEEQKGTGKRSIEDPDMTGQPPLKRRLLEEFDRTVDGPRGSTLHPEKSCP
NGVMKDRRVFKYHVSLHPNITRPDSNGKNYVETTLQKTTPTQHSTPGDSRSTQSNMPAFV
PPFLKNTKTESSMNTELKDMRPPSAFVPPFKKQRTLVQVNSSRPQEEEDKHHHLFVTPFN
SNTFVPPSKKTPTTTDITGDRNKEGIQTVALADTANDHMMNNQNLPIGCGSEDSAAEASH
VEDTLSTSQDMFQNLQNIDLARDMQDMRIRKKKRQTIRPLQGSLFLTKTSGVSRIQLKAA
VNGRPPARYTQKQLYGHGVHQHVYGITSETAESFRFSLQQFIKQEAFIDGGGDQLADGGW
LIPRRDGTAGKEEFHRALCDTPGVDPKLITEEWVYNHYRWIVWKQASMERSFPKTMGSLC
LTPEQVLLQLKYRYDVEVDHSCRPALRKIMEKDDTSAKTLVLCVCGVVSRGHSPNSFGDT
KTPQGADAKAENPFAVVWLTDGWYAIKAQLDEPLTAMLHKGRVCVGGKLIIHGAQLVGSQ
DACSPLEAPESLMLKICANSSRPARWDAKLGFHRDPRPFLLPISCLYSGGGPVGCVDIII
LRSYPIQWMERKPDGGTVFRSIRAEEKEARRYDSHKQKAMEILFAKIQAEFEKEDKGCNK
TQRRRRTISRQDIKSLQDGEELYEAVGDDPAYLEAHLSEQQLETLRTYRRTQMEKKQAEL
QDRYRQALENAENSEGSCPKRDVTPVWRLCIADSMEQPGNGVSLVYQLNLWRPSSDLQSL
LKEGCRYKVYNLTTSDGKKHGGSTTLQLTGTKKTQFQDLQASREWLSTHFHPRVSTDFVD
LQNPEFQPLCGEVDLTGYVITVIDGQGLSPAFYLTDGKLNFVKVRCFSSFAQSGLEDLVK
ARVLLALSNLQLRGQSMSPTPVVYAGDLTVFSTNPKEVHLRESLSQLRTLVQGQENFFTV
AEEKLSNVVKSDSLRSVSSPALQTRTPASATVRRQDTKTSVTPQQPVRSLGSFTPVSRKQ
PAANSSTEKEHSSLKRRRALDYLSRIPSPPPLSPLVPVASPCVKKTFNPPRRSGTLSTLK
TAPKTAQTPACKPVSSPLEDEWVNDEELAMIDTQALHVGDLL
NT seq
9129 nt
NT seq
+upstream
nt +downstream
nt
atgaattttccctcaaaaaacatgtacgacacgtataaagatgaaatctggaaagagctg
ggaccactggaccccaactggtttgaggcattgacagctcaaacattcacgaatgaggga
aatgtctctgatcaagatgacctgtgtgctaaccaagaggggaattttaaaacacccctt
gacaaagctgcagtagacagtcagctgttttcaacccccaaagttttcagaaaaagtcga
gttgtgtcacctgaaactgaggatgagcactcgttcaccgctgaacaagaaaaagagaca
ttgacatggatggcaacacaaagtccgtgtatgtttcgggtgtcaaaaatgggggtccca
ggtgagaaatatggaggttttcagcctcagagtcagagcagctttgatctgcttcatacg
ccacaaaaatccccagtcagccacgccaagcatatatctgaaagtctcggtgcacagatt
catcctgatatgtcatggaccagttctctgaataccccaccagcagtaccatccaccttg
attttatctaaaactgatgagagtccctgtccagtgagagtttctccagataaaaatgtt
gttattgtgcggaagcttttcccttcactttcaaatgcttccagaattgaagtggtgtca
cccaaaaacaatgacatacctaccattcaccaaggtgttgtttcccctgaggcaagtcag
aatccagagacccacaactccccccagagttctctgaatcagagtgatggtgtttggaaa
cagaagctaccggatgctgttgaggatggagaaatttgcagaacaggaccaggtgttctt
gatggagctgaaaatgttctctctccatttttcaccaacagtagttcagcactaagaaaa
gtgaagactgacagagtcaaaagaaagcaaatcattccaacaaaagaggatgcagacaac
aatgcaaatggtgctgcatccagtgaacagagaacagatgaccaggaacctggcagactt
ccttcatccccacaagtgaaaactggagatattgaaatcacccagtggtctccgttgagt
ttatctgaaattccaccttgtactgtggatagcgcttgctatgatagtagtcctgctcaa
gtggaaaacaaaatgttaacagaacaactgcagagtgactctgtttttagcctgccagtc
agaccacccatgaaaaccccagattctggatggaccaagaaaaagagaaaatttgtttac
actgtaaagactccagaagttcaaggaaaagaagcacagtctcagaggatggactcgtca
ccaggacaagaagttcacgtgaagcagtctgggaaagcccaagatgaagcggactcttgc
agtatcgggaagaaagagatgcaaaaacaaggaaatgtagcagaagaaagtttacctcct
ttcgtacaaggaaaagtccaggatcttgacatgtcgcagctttgcagagattttgcacaa
gacttcagtcaaatgttagaccccagtaaaccaagtaaagaagcagagtatactcctcaa
gacggcttctctccatcagcttgtctgtcagccgtgaaacaagctaaacagaaagcagtg
caagcaaacctttaccatgactgtgatggcgtcagtaacagaaagcatgtttctaccact
aatccaaaaaactccatcagtgagggcacagtaagtgacagtggattccagtctgctgtt
gcagatagcacccacgtgacagcatcatcatttgttcttcccagctcagagatcaatggt
gaaagtcaacagtggactggctttaaaacagacatgcacagaacaactcctttcgcatct
tcaagtaaaggaaatggaaaagaacatttggatgatatttcacaaggagctgaaacagat
gccaagctgcccagtacaatcaggggaagccagacactgggccttggcagagagagtgag
ttgcccatagaaagcacatcggcacaactacccagcagtacaaaaggaactgtcgataac
attaattgcgttccacttaatggtcaagctcatggcagtctgccacagaaaacaacagtt
tctcttccttccgtccatacatcaggattcaaaacagcttcaaataagggtatacacatt
tcctcagccaatctgaagaaagccaagcgtctctttgaagagattgagggggaaagaact
gtaagtgagcagcccaccatatgtgaccatggcactaaagaagaaattagcgtgagttgt
gaatcagtgaaaaatccaaccacaatgtcaaaccagccactttgttcaagtgaaaaaaat
gtggatattagttgccacttaacagcttcacaaaaagctgatgtgactgagatttgcact
ctcttggaagaagcagatactcagtttgaatttacacagtttaaaactgcaaacctaaaa
caacatagtcaagataatgctacctctccccaaaaagttgacaaagaacttgaccctgat
tttctttcaggtatagattttgatgacagttttagtgcagaggctgaaaagcacgtggca
gtaactgtatcgcaggacaaaataaccttagcttcagatggtaaaacaaattgtgaaaca
tcgaacgtcacaagtaaatctacaggtttgtcattgtcaagtgcaatgaaaatagaaaat
ccctctacggaagctgtttcttcctcttcaaagcagatctctgaaggcagtagcagaatt
atgtcagctgaacccaaaaatctagacagcactgggcaccctgaaacaagcaagctggag
aacaaaaatcctgtaatgcttggtgtgggatttaagactgcaggaggaaacattttgaga
gtttcaaaaacatgtctaagcaaagccagagctttgtttgcagatttagaggataatctt
gtgacaagtcaaaaatcactggacaagcagtgtagcaaaactaacgctgaaacacagcat
aagcacagtggggataatcacactggtaatgttttgcttcataaagatgacaaatcagag
ttcataggtaatgatacaggagggagcattcagggctgtttttccaaaatgaaggagtat
gtctcttcatacaaacaggtcacaagcattagagatgatgtgacaggaaatttgaaaaat
agcaaactggacacaaccacatgtcaaagtgggttcctgatggccagtgggagaaatatt
tctatttcagcaaaagctatgcaagaggcagatgctttcttcaaagactgtgactccatg
gacactaacactggcatgccagtgaaacataaaaagagcatggaacccttgcctggaagt
ttgagtcataaggaaacccttccaaaatgtaaaaatgttcaggggataaatgtcaaagtc
tctgaagagccaatcaatgagtttgaaaatggaaatgctggaccaactgcacgccataca
gaggttgtacaacataatgtggaggttcccaattttggctttaagaatacaccaatgtta
acaaatgcggtcccctctttgactgcaaaggcactttcatctctctcgtgcacaacatca
aagaattttggctcctcaagtggtggattttccacagccagtgggaagaaagtatccctg
tcagctgatgcaatgaaaaaagcagaatgcctactgaatgaaattcatacacttgaggac
actaaccaacaactgaagcaaaagggagatgctttcagatcaagtcatctcaccagtcag
attcagataccacctaaaaatgttggctttcagacagccagtggcaaaggatttgccatt
tcatctgcagctctcaagaaagcaaaattgctgttgagtgaatgtgatgtagttgaggac
gaaattggtgcgaaaccaacacattcaaagatgccagttcctccactaccaccaaagaat
agcggatttcttgcagccagtggcaaaccagtgacattttcatctgaggccctccagaag
gcaaaaactctcttcactgacatcagtttaagtacagagatcccagctgcttcaggctca
aagaccactgacaggaaaaaagccaattctgaaaacacggagaaaatacattgtggtttc
acaactgcagggggagctaaagtccatgtgtcacagaaaaatctgttgaaagcaagaaac
cttttgaaagaatttgatgatggttgtatttcagcaaaagcaatgcaagaaacagatgtt
ttctttgaagactgtgacattaatgatgctatttcagtaaaacataaaagtgtaacacct
gtgagtggaagtggaagtgagaagaaaaaaccctcagaatttaaacaagatcaaagggtg
acaaacatttacagagaacctggaagtggacacactgactttgaaaatgttaacgtggga
ccagttgtaaaccatgagaagatgctgcatcccaatgctgtggagaacgacaaaggtgtt
ttaaagggcacattggattctttcaaagcagcttctttacatggaaacccatcgatggca
aagccacgttctccagtgttgtgcacaacatcaaaaaacattagttcttctgccattaat
gaatcaagcaacattggtagattctgtacagccggcgggaaaaaagtaaccgtgtcagat
gatgcaatgacaaaagcaaagtctctattgaacaaaagtgctacatttgaggacacaaac
aaacaactgaaacaaaaggaagatacttttccacaaaacaatggggggtttcagacagcc
agtggcaaaggagtagctatttcatctgcagccctaaagaaagcaagaattctgttaagt
gaatgtgaaggagctgatgatgaaattggtgtaaaacctacacattccaagactccagtt
gccactagtgtgccacccaagaatagaggatttcttgcagcgagtggtaagccagtggca
ttttcatctgaggccctccaaaaggcagaagctctcttcagtgacatcagtttcagtaca
gagattcctgctatgtcagacacaaggaacactgacaagaaacacagcaattctgaaatt
acagagaaaatgcattgtggtttcacaactgcagggggagcaaaagtccatgtgtcacag
aaaaatctgttgaaagcaagaaaccttttgaaagaattttctgatggacagtgtcatgtc
tcaaacgcatcgtcaagagggccagacgacaccaataagtcagatctatcaaaagtgaaa
gatgtgaacaaagcttcaaattctaatctcagcataccctgtgacaaggaaatcccttct
aagtttagtgcccctcaggtagttaaacctttgcaagacactgaccatgaaaaggaaaca
cttcaaactccaagtgtacctggtggtgttttagccaaagacaaggcacttccagattca
tataagtctaaaagagacaaaatgaccccatcagggtcgtgcatcagtaacagtcctgga
gagggaatgtcaagtctattggactacgaaaaaaatcagacaagcagcagcgacgaatct
aaggtcaaaaggccacaagactcttcagtcctaaactttcaggcatttaacctcagtggt
tgcactgaaacccagcagatgtttttcgcccaggaagctctggactgcactaaggctttg
ttagaggatgaaagtctggctggccaaagtctctcaatgactttagaaactgtgccactg
caagataaccctaggtccagctgcaaatctgtagaggagcaaaagggaacagggaaaaga
tcaatagaggacccagatatgactggtcagcctcccctgaaaagacgattactggaagaa
tttgacaggacggttgatggtccgagaggttcaacactccatccagagaaaagttgtcca
aatggtgtaatgaaagacaggagagtttttaagtaccatgtctctctccatccaaacatc
acaaggccagacagcaatggaaaaaactatgtggaaaccacattgcaaaagacaacacca
acacaacactcaaccccaggagacagtagatcaacacagtccaacatgccagcgtttgtt
cctccattcctcaagaatacaaagacagagagttccatgaatacagagctcaaggacatg
agaccaccttctgcattcgtacctccattcaagaaacaaagaactcttgtccaagtgaac
tcctctagaccacaggaggaggaggataaacaccaccatctgtttgttacaccctttaac
agcaatacttttgtaccacccagtaaaaaaacaccaaccacaacagatataacaggtgat
agaaacaaagaaggcattcagacagtggccttggctgacactgcaaatgatcatatgatg
aataatcaaaaccttcctattggctgtggatcagaggactctgctgcagaagcttcacat
gtagaggacacattgtccacaagccaagacatgtttcagaatcttcaaaacatagacctg
gcacgagatatgcaagatatgaggatcaggaagaagaagcgccagaccattcgacctttg
cagggcagtttgtttctaaccaaaacctcaggagtatcgaggatacagttaaaagctgca
gtaaatggaaggccacctgcaagatacacccaaaaacagctgtatggacatggagttcat
cagcacgtgtatgggataaccagtgagacggcagaatcttttcgcttcagtttacagcag
ttcatcaaacaggaggcatttatagatggaggtggtgatcagcttgctgatgggggatgg
ctgatccccaggagggatgggactgcagggaaagaggagtttcatagagcattatgtgac
acaccgggggtggatcctaaactgatcactgaggagtgggtgtacaatcactaccgatgg
attgtgtggaaacaggcctccatggaaagatcatttccgaaaacaatgggcagcctctgt
ctcactccagagcaggttctccttcaactcaagtacagatatgatgtagaggtggaccac
agctgcaggccggctctgagaaagatcatggaaaaggacgacacatcagccaaaaccttg
gtcctctgtgtttgcggcgtcgtctccaggggtcactccccaaacagtttcggtgacaca
aagactccacaaggtgctgatgccaaggctgaaaacccctttgcagttgtctggctgaca
gatggatggtatgccattaaagcccagcttgacgaacctttgactgccatgcttcacaaa
ggtcgagtgtgtgttggtgggaagttgatcatccatggggctcagctggtgggatcacaa
gatgcttgctcccctctggaggcacctgaatctctcatgttaaagatttgcgccaatagc
agcagaccggcacgatgggatgctaaactgggatttcacagagatccacggccattcctg
ctgcccatttcctgtttgtacagcggtggaggaccggtaggatgtgtggacattatcata
ctgagaagctaccccatacaatggatggagaggaaaccagatggaggcactgtgtttcgc
tctattcgtgcagaagagaaagaggcgagacgatacgacagccacaaacaaaaagctatg
gagatcctatttgccaagattcaagctgaatttgagaaagaagacaaaggttgtaacaag
actcagcgtagaagacggacaatcagccgtcaggatattaaaagtcttcaagatggagag
gagctctatgaagcagtgggggatgatccagcctaccttgaggcacatttgagtgaacag
cagttggagactctacgtacctacaggcgcactcagatggagaagaagcaggctgaactg
caggatcgttaccggcaagctttagaaaatgcagagaacagtgaaggtagctgtcccaag
cgagacgttacacctgtgtggagactctgcattgctgactccatggagcaacctggcaat
ggtgtgtctttagtttaccagctgaacctttggcgaccttcgtcagatcttcagtcttta
cttaaggaaggctgtcgatacaaagtctacaacctcaccacttctgatggaaagaaacat
ggtggtagcacaactcttcagctgactggaacaaagaaaacacagtttcaggacctgcag
gcttctcgagaatggttatcgacacattttcatccgagggtctctaccgattttgtggat
cttcaaaacccagaattccagccgctatgtggagaggttgatctcacaggatatgtcatc
actgtcatagatggacagggtttgtctcctgcattttatttgaccgatgggaaactgaac
ttcgttaaagtgcgctgtttcagcagctttgctcagtctggcttggaagacctggtaaaa
gcacgtgtcctgctggctctgagcaacctgcagctgagaggccagtccatgtctcccact
cctgttgtgtacgctggagatctgaccgtcttctcaacaaaccccaaggaagttcaccta
cgggaatccctcagccaactcagaaccctggtccagggtcaggagaacttctttacagtt
gctgaggagaagctttcaaatgtagtcaaatctgacagcctgaggtccgtctcctctcct
gctctgcaaacacgaaccccagcttctgcaacagtcagaagacaagacacaaaaacaagt
gtgacacctcagcagccagtcagaagcctcggatccttcactccggtcagcaggaaacaa
cctgcagcaaacagttcgacagagaaggagcacagcagcctgaagcggaggagagctctg
gactatctgtctcgtatcccatctccaccacctctctccccgctggtgccagtggcttct
ccgtgtgtaaaaaaaacattcaacccccctcggaggtccgggacactcagcactttaaaa
actgcaccaaaaactgcacagactccagcttgcaaacctgtcagttcaccgctggaggat
gaatgggtgaatgacgaggagttggcaatgattgatactcaggcattgcatgttggtgat
ttactgtag
DBGET
integrated database retrieval system
