Epinephelus lanceolatus (giant grouper): 117259641
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Entry
117259641 CDS
T07331
Symbol
bckdha
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
ely
Epinephelus lanceolatus (giant grouper)
Pathway
ely00280
Valine, leucine and isoleucine degradation
ely00640
Propanoate metabolism
ely00785
Lipoic acid metabolism
ely01100
Metabolic pathways
ely01210
2-Oxocarboxylic acid metabolism
Module
ely_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ely00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
117259641 (bckdha)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
117259641 (bckdha)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
117259641 (bckdha)
Enzymes [BR:
ely01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
117259641 (bckdha)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
117259641
NCBI-ProteinID:
XP_033487041
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Position
9:complement(18101307..18106461)
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AA seq
446 aa
AA seq
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MAAVRSMNKMYGLCFHAVRQTAGLKASRLLQHRAFRVGAVHRQQPFDSSLEKPQFPGASA
EFVDQLEFIQPNVISGIPVYRVMDRQGNIINPSQDPQLSKETVLNFYQKMTMLNTMDRIL
YESQRQGRISFYMTNYGEEGTHIGSAAALDPSDLVFGQYREAGVLMYRGFPLEMFMAQCY
GNADDLGKGRQMPVHYGSKDLNFVTISSPLATQIPQAAGAAYAVKRENLNRVVICYFGEG
AASEGDAHAGFNFSATLECPLIFFCRNNGYAISTPTNEQYRGDGIAARGPGYGMLSIRVD
GNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH
PISRLRHYMAARGWWSEDDERSWRKKSRKTVMEAFEGAEKRLKPNPELLFTDVYQEMTSQ
LSKQRESMRRHVSQYKEHYPLDLYDK
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atggcggctgtgaggagtatgaacaaaatgtatggactctgtttccatgctgttcgtcag
acggcaggactgaaggcgtcgaggctgcttcaacacagagccttcagagtcggtgctgtg
caccgacagcagccctttgactcatctctggaaaagccacagttccctggagcctcggcc
gagtttgtggatcagcttgagttcatccagcccaatgtcatctctgggatcccagtgtac
cgggtgatggacaggcagggcaacatcattaacccctctcaagaccctcagctctccaaa
gagacagttttaaacttttatcagaagatgactatgctaaacacaatggatcgcattctt
tatgagtctcagagacagggtcggatctctttttacatgaccaactatggtgaggagggg
acacatattggtagtgctgctgctctggacccaagcgacttggtctttggtcaatacaga
gaagctggagtgctgatgtaccgtggttttcctctggagatgttcatggctcagtgctac
ggcaacgcagatgaccttggcaagggccggcagatgcctgtccactacggctccaaagat
ctgaactttgtcaccatctcctctcccttggccactcagattcctcaggcggctggagct
gcatacgcagtcaagcgagaaaacctcaaccgtgttgtaatctgttacttcggagaggga
gccgccagcgaaggggatgcacacgctggcttcaacttttccgccacccttgagtgccca
ctgatattcttctgtcgtaataacggctatgccatctctacccccaccaatgagcagtat
aggggagatggcattgctgctcgtggtccgggttatggcatgctgtccatccgtgttgat
ggtaatgatgtgtttgctgtgtacaatgctacaaaagaggcacgccgcagggctgtggct
gagaaccagcccttccttattgaggcaatgacctacagaattggacaccacagcaccagt
gacgacagctcagcttaccgttcggtggatgaagtgaactactgggacaagcaggaccat
cccatctcgaggctgagacattacatggcggcccgaggttggtggagcgaggacgatgag
aggagctggcggaagaaatctcgcaagacggtgatggaggcgttcgagggggccgagaaa
cgccttaaaccgaatcctgagctgctgtttactgatgtgtaccaggagatgacatcccaa
ctgagcaagcagagagaatccatgcggaggcacgtgagccaatacaaagagcactaccca
cttgacctttatgataaataa
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