Epinephelus lanceolatus (giant grouper): 117271943
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Entry
117271943 CDS
T07331
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
ely
Epinephelus lanceolatus (giant grouper)
Pathway
ely00562
Inositol phosphate metabolism
ely01100
Metabolic pathways
ely04012
ErbB signaling pathway
ely04068
FoxO signaling pathway
ely04070
Phosphatidylinositol signaling system
ely04081
Hormone signaling
ely04140
Autophagy - animal
ely04150
mTOR signaling pathway
ely04210
Apoptosis
ely04218
Cellular senescence
ely04370
VEGF signaling pathway
ely04510
Focal adhesion
ely04620
Toll-like receptor signaling pathway
ely04625
C-type lectin receptor signaling pathway
ely04810
Regulation of actin cytoskeleton
ely04910
Insulin signaling pathway
ely04914
Progesterone-mediated oocyte maturation
ely05100
Bacterial invasion of epithelial cells
ely05132
Salmonella infection
ely05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
ely00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
117271943
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
117271943
04370 VEGF signaling pathway
117271943
04068 FoxO signaling pathway
117271943
04070 Phosphatidylinositol signaling system
117271943
04150 mTOR signaling pathway
117271943
09133 Signaling molecules and interaction
04081 Hormone signaling
117271943
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
117271943
09143 Cell growth and death
04210 Apoptosis
117271943
04218 Cellular senescence
117271943
09144 Cellular community - eukaryotes
04510 Focal adhesion
117271943
09142 Cell motility
04810 Regulation of actin cytoskeleton
117271943
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
117271943
04625 C-type lectin receptor signaling pathway
117271943
09152 Endocrine system
04910 Insulin signaling pathway
117271943
04914 Progesterone-mediated oocyte maturation
117271943
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
117271943
09171 Infectious disease: bacterial
05132 Salmonella infection
117271943
05100 Bacterial invasion of epithelial cells
117271943
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ely04131
]
117271943
Enzymes [BR:
ely01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
117271943
Membrane trafficking [BR:
ely04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
117271943
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_C2
PI3K_rbd
PI3K_p85B
DUF2321
ABC1
Retrotran_gag_4
Ribosomal_S15
Colicin-DNase
Motif
Other DBs
NCBI-GeneID:
117271943
NCBI-ProteinID:
XP_033506401
LinkDB
All DBs
Position
19:14649458..14672753
Genome browser
AA seq
1037 aa
AA seq
DB search
MPPRPSSGELWGMHLMPPNILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
TFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMAIIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDSDNEQLRQVCNRDPL
SEITEQEKDFLWRHRQDCLNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALD
NT seq
3114 nt
NT seq
+upstream
nt +downstream
nt
atgcctcccaggccctcctcaggagaactatgggggatgcacttgatgccccccaacatc
ctagtggactgccttctgccaaatggcatgattctcacattggaatgcctccgggaggcc
acgctgatcacagtcaagcatgagcttttcaaagaggccaggaagtaccctctttaccat
ctgctgcaggaggagagctcctacatctttgtcagcgtcacccaagaggcagagcgggag
gagttttatgacgagaccaggaggttgtgcgatctcaggctctttcaggccttcctcaaa
gtcatcgagccagtgggcaacagagaggagaaaattcttaacagagaaataggttttgcc
attggaatgcctatatgtgagtttgatttggtgaaagactcagaagtgcaggacttcaga
aggaacattttaaatgtttgcaaagaggccgtggacctcagagacagtaacggaccccac
agcagagctttgtacgtgtatcctcccaatgtagaatcctccgcagaacttcccaggcac
atctataacaagctagataaaggtcaaatcattgtggtgatatgggttattgtgtcaccc
agcaatgacaagcagaagtacaccctgaagatcaaccacgactatgtgccggagcaggtg
attgccgaagccatccgtaagaagacacgtagcatgctgctctcccaggagcagttaaag
atgtgtgtgcaggagtatcagggaaagtacatcctcaaagtctgcggctgcgacgagtac
ttgctggagaaataccctctgagtcagtacaagtatgtgcgcagctgtatcatgctggga
aggatgcccaacttgatgctaatggcaaaagacagcctgtattcccagctgcccatggac
actttcaccatgccgtcatacgcgcggcgaatatccacagcaacgccctacatgaatggg
gaaacagccacaaagtctctctggactatcaacggaacgctgaggatcaggatactgtgt
gccacttacgtcaatgtcaacatcagagacattgacaagatctacgtcaggacggggata
taccacggtggagagcagctgtgtgacaatgtcaacactcagcgcgtgccctgctcgaac
cccaggtggaacgagtggctgaactacgacatgtacattccagacatcccccgtgctgcc
cggctctgcctctccatctgctctgtgaaaggaaggaaaggggcgaaagaggagcactgt
cctctggcctggggcaacatcaacctgtttgactacacccacacattagtatcagggaag
atggctctcaacctatggcctgtcccacacggcctggaagacctgctcaacccaatcggt
gtcactggctccaaccccaacaaggaaacaccttgtctggagctggagtttgaccatttc
agttgccccgtcaagtaccccgatatggccatcatcgaggaccacgcaaactggaatata
tccagagagcttggctttaattactgccacaccggtttgagtaacagactggcgcgtgac
aaccccctgactgacagcgacaatgagcagctacgccaggtgtgtaacagagacccgctg
tctgaaatcactgagcaggagaaagactttctgtggaggcacagacaagactgcctcaac
atgccagagatcctccccaagatcctcctggctgtgaaatggaactccagagatgagatt
gcacagatgtattgcctcctgaaggactggcctgctatcaagccagagcaagccatggag
ttgctggattgcaacttccctgaccctatgatcagagagtttgctgtaaagtgccttgag
aaatacctaactgatgacaaactctcacagtacctcattcagctggttcaggttctaaag
tatgagcagtaccttgacaacccgcttgcacgcttcctgctaaaaaaggcattaaccaat
caaaggataggacatttcttcttctggcatttaaagtcagagatgcacaacaagacagtc
agccagcggttcggcctgctgctcgagtcgtactgccgggcctgtggcatgtatctgaag
cacctgagcagacaggtggaggccatggagaaactcatcaatctcactgacctcctcaaa
caggagaagaaagatgaggcgcagaaggttcaaatgaagtttctggtggagcagatgaga
aggcctgattacatggacgccctgcagagcttcacctccccactgaatccagcacatcag
ctgggaaacctccgcctggaggaatgcaggatgatgtcgtcagccaagcggcctctatgg
cttaactgggaaaatccagatatgatgtcagaactgctctttcagaacaacgaaatcatc
ttcaaaaatggagatgatctgaggcaggacatgctgacgctgcagatcattaggataatg
gagaacatctggcagaaccaaggccttgatctcaggatgttgccatatggttgtctgtca
atcggcgactgtgtgggtttgattgaggtggtgaggaactctcacaccatcatgcagatc
cagtgtaaaggcggcctaaagggggcactgcagttcaacagccacacactgcatcagtgg
ctcaaggataagaacaagggagagatgtatgaccaggccatagatctgttcacacgttca
tgtgcaggctactgtgtagccacgtttatcctgggcataggggacagacacaacagcaac
atcatggtcaaagatgatggacagctgttccacatagacttcggccatttcctcgaccac
aaaaagaagaagtttgggtacaagagagagcgcgtgccctttgtgctcacacaggacttc
ttgatcgttattagcaaaggaactcaagagtgcaccaaaacaagggagtttgaaaggttc
caggagatgtgttacaaggcgtacctggcaatccggcagcatgccaacctcttcatcaac
ctcttctccatgatgctgggctcagggatgcctgagctgcagtcgttcgacgacatcgct
tacattagaaagacgctggctttggacaagacggagcaggaggccctggactaa
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