Epinephelus lanceolatus (giant grouper): 117272055 Help Entry 117272055         CDS       T07331                                  Symbol egfra Name (RefSeq) epidermal growth factor receptor   KO K04361   epidermal growth factor receptor [EC:2.7.10.1] Organism ely  Epinephelus lanceolatus (giant grouper) Pathway ely03272   Virion - Hepatitis viruses ely04010   MAPK signaling pathway ely04012   ErbB signaling pathway ely04020   Calcium signaling pathway ely04068   FoxO signaling pathway ely04144   Endocytosis ely04510   Focal adhesion ely04520   Adherens junction ely04540   Gap junction ely04810   Regulation of actin cytoskeleton ely04912   GnRH signaling pathway Brite KEGG Orthology (KO) [BR:ely00001]  09120 Genetic Information Processing   09125 Information processing in viruses    03272 Virion - Hepatitis viruses     117272055 (egfra)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     117272055 (egfra)    04012 ErbB signaling pathway     117272055 (egfra)    04068 FoxO signaling pathway     117272055 (egfra)    04020 Calcium signaling pathway     117272055 (egfra)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     117272055 (egfra)   09144 Cellular community - eukaryotes    04510 Focal adhesion     117272055 (egfra)    04520 Adherens junction     117272055 (egfra)    04540 Gap junction     117272055 (egfra)   09142 Cell motility    04810 Regulation of actin cytoskeleton     117272055 (egfra)  09150 Organismal Systems   09152 Endocrine system    04912 GnRH signaling pathway     117272055 (egfra)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ely01001]     117272055 (egfra)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:ely04147]     117272055 (egfra) Enzymes [BR:ely01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      117272055 (egfra) Protein kinases [BR:ely01001]  Receptor tyrosine kinases (RTK)   EGFR family [OT]    117272055 (egfra) Exosome [BR:ely04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    117272055 (egfra)   Exosomal proteins of pancreatic cancer cells    117272055 (egfra)   Exosomal proteins of bladder cancer cells    117272055 (egfra) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr GF_recep_IV Recep_L_domain Pkinase Furin-like TM_ErbB1 ABC1 Haspin_kinase Kinase-like Motif Other DBs NCBI-GeneID:  117272055 NCBI-ProteinID:  XP_033506664 LinkDB All DBs Position 19:4074137..4137240 Genome browser AA seq 1196 aa AA seqDB search MATRLVKWISLTSLLCLGCSVLAEGKVCQGIANRLNLLGSREDHYLNMVKTYSNCTVVLE NLEVTYMEEHHDLSFLSSIEEVGGYVLIALNTASRIPLQNLRIIRGHKLYEGLYGLAVLT NYNKHTGQDTDELLLTSLTEILKGGVKFGTNQPCNVETIQWYDIVNAESKPKMVLPSPNS PRRCKKCDPSCFNGSCWAPGPENCQILTKLNCAQQCSKRCKGPSPSDCCNEHCAAGCTGP RPTDCLACRDFQDDGVCKDSCPGLMRYDPNLHQLVPNPHGKYNFGATCVKSCPHNYVVTD HGACVRTCSGNTYEVDEGGVRKCAKCDGLCPKVCDGLGSGNLTHTLSVNATNIDSFKNCT KINGNIAIIRTSIHGDPYTKTPKMEPAQLEVFKTVKEITGYLLIQMWPESLSSLSPFENL EIVRGRTKRGSRSLMMAQLGISYLGLRSLREISDGDVVIMKNPNLCYTDKSHWKGLFKSE SQSATIEENADAATCALRNNTCDRKCSTDSCWGPGPDMCFACRDYSRDGSCVDSCNILEG DLRETVVNKTCVECHPECQRMNGTATCSAPGPGNCTKCANFQDGLFCVSRCPQGVPGEDD TLVWKYADTMQVCKPCHKNCTQGCMGPGLEGCQGKGPSGLSMIAAGVVGGLLAVLIAGLS VFVLLRRRHIKRKRTMRRLLQERELVEPLTPSGEAPNQALLRILKEPEFKKIKVLGSGAF GTVYKGLWVPEGEDVKIPVAIKVLREATSPKANKEILDEAYVMASVEHPHVCRLLGICLT STVQLVTQLMPYGCLLDYVKENKDNIGSQYLLNWCVQIAKGMNYLEERHLVHRDLAARNV LVKTPQHVKITDFGLAKLLSADEKEYHADGGKVPIKWMALESILNRTYTHQSDVWSYGVT VWELMTFGTKPYDGIPASDIAGVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPRFRE LIAEFTKMARDPSRYLVIQGDDRMHLPSPTDTKLYRSLISGEDMVDAVDADEYLVPQHGF FSSQSTSHTPLLHSTSLNSSIGTCHSRAGLLNGFPSRDGSMVLRYIPDPTDKLLDEAFLP SPDYMNQNGVSDMMNPIYQHPGPPRTVLPTISSEDTETEYLNCFKNGTDGPEYLNEIPSP AILPLTSNGTVPSIQKYQPQNSIDNPDYQQDFSPTFKSHANGHIPAAENTEYLGPD NT seq 3591 nt NT seq  +upstreamnt  +downstreamnt atggcaacccgtttagtgaagtggatcagtctcacctctctgctgtgcctgggctgctct gtcctggcggaagggaaagtatgccaaggcatcgccaaccgtttaaacctgctgggttcc agagaggatcactaccttaacatggtgaagacctacagcaactgcactgtggtcctggag aacctggaggtcacctacatggaggagcaccacgatctgtccttcctctcgtctattgaa gaagtgggcggctatgtgctgatcgccctcaacacagcctccaggattcctctgcagaat ctgcgcatcattcgaggtcataagctctatgagggactgtatggcctcgctgtgcttacc aattataacaaacatacaggtcaggacaccgatgagcttcttctgaccagcctgacagaa attcttaaaggaggtgtaaagtttgggaccaaccagccatgcaatgtggaaacaatacag tggtatgacattgtcaatgctgagagcaaacccaaaatggtgcttccatcacccaacagt cctcgacgttgtaaaaaatgtgacccaagctgcttcaatggttcatgctgggcacctggt cctgaaaactgccagatcttaacaaagctgaactgtgcacagcagtgctcaaagagatgc aaagggccttcacccagtgactgttgtaatgagcactgtgctgcgggctgcacaggaccg cggcccaccgactgtctggcctgtcgggacttccaggacgacggggtgtgtaaggactcc tgccccggcctcatgcgctatgaccccaacctgcaccagctggttcctaacccacatgga aagtacaacttcggggccacgtgtgtgaagagctgcccacataactatgttgttactgat cacggagcgtgtgtgcggacgtgcagtgggaacacatacgaggtggacgagggaggagtc aggaagtgcgccaagtgtgacggactgtgtccaaaagtgtgtgatggacttggatcagga aacctgactcacactctgtctgtcaatgccaccaacattgactctttcaaaaactgcacg aaaatcaatgggaacattgctatcatccgcacatcgattcatggggatccgtataccaaa acaccaaagatggagcctgcccagcttgaggtgtttaagacagttaaggaaattactgga tacttgttgattcagatgtggccagagagcctgagctcactcagtcctttcgagaatctg gagatcgttcgaggacgaactaaacgtggtagccgcagtttgatgatggctcagctcggc atcagctacttgggcctccgctccctgagagaaatcagcgatggagatgtggtcatcatg aagaacccgaacctgtgctacactgacaaaagccactggaagggcctcttcaaatcagaa agccagagtgctaccatagaggaaaatgctgatgctgccacatgtgccctgaggaacaac acttgtgacaggaagtgttccacggacagctgctggggccctggcccggacatgtgtttc gcctgccgtgactacagccgtgatgggagctgtgttgactcctgcaacatcctggagggg gatctgcgggagactgtcgtgaataaaacctgcgtggagtgtcaccccgagtgtcaacgc atgaatgggaccgcaacctgcagtgcgcctggtcctggaaactgcactaagtgtgccaac ttccaagacggcctgttctgtgtgtcccggtgtcctcaaggcgtgccaggcgaggacgac acgctggtgtggaaatacgcagatacgatgcaagtgtgcaagccctgccacaaaaactgc actcaaggttgcatgggtcctggtcttgaaggctgccaaggtaaaggcccctctggcctt tccatgattgcggctggtgtagtcgggggtctgctggctgttcttattgctggcctgtct gtgtttgtgttgctgcgccgacgccacatcaagaggaagagaaccatgcgtcgacttctc caagagagagagttggttgaacctctgactccaagtggcgaggctccaaaccaggctctg ctgcggatcctgaaggaacctgaatttaagaaaatcaaagtgctgggatcaggagctttt ggtactgtttacaagggcctgtgggttccagagggagaggatgtgaagatcccagtcgcc atcaaggttttgagggaggccacatcgccaaaagcaaacaaagagatcttggacgaggct tatgtgatggccagcgtggaacacccccacgtgtgtcgtctgctcggcatctgcctgacg tccacagtgcagctcgtcacccagctgatgccctatggctgcctgctggactatgtcaaa gagaacaaggacaatatcggctcccagtacctgctcaactggtgtgtgcagatagccaag ggtatgaactacctggaggagcgccacttagtgcaccgtgacttggcagcgagaaatgtc ctggtgaagactcctcaacatgtcaagatcactgactttggtctggcaaaactcctcagt gcagatgagaaagagtaccacgccgatgggggaaaggtgccaataaaatggatggctctt gaatctatcctgaacagaacatacacacaccagagtgacgtgtggagttatggcgtaaca gtttgggagctgatgacatttgggaccaaaccgtacgatgggattccagccagtgatatc gccggggttctggagaaaggggagcgactgcctcaaccaccaatctgtaccatagacgtc tacatgatcatggtgaaatgctggatgattgatgcagacagccgacctcgtttccgagaa ctaatagctgaattcacaaaaatggcccgggatccttctcgatatcttgtcattcaggga gatgaccgcatgcacctgccgagtcccacagacactaaactgtaccgcagcctgatcagt ggggaggacatggtggatgctgtggatgcagacgagtacctggtgccgcaacacggcttc ttcagcagccagagcacctcccacacaccactgcttcactccacgagcctcaacagcagc attggaacgtgccacagcagagctggcttactgaatggattcccgagcagagatggaagc atggtgctccggtatattcctgaccccacagacaaacttctagacgaggccttcctgccg tctccagactacatgaaccagaatggagtctcagatatgatgaatcccatctaccagcac ccgggtccacctcgcaccgtgcttcccaccatctcttcagaggacacagagacggagtac ctgaactgctttaaaaacgggacagacggaccagagtacctcaacgagatcccgtccccc gccatcctcccgctcacctccaacggcacggttcccagcatccagaaataccagccccag aacagcatagacaaccctgattaccaacaggatttcagtcccaccttcaaaagccacgcc aacggacacatcccagcggcggagaacacagagtacctgggcccggactga

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