| Entry |
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| Symbol |
top2a
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| Name |
(RefSeq) DNA topoisomerase 2-alpha
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| KO |
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| Organism |
emac Eleginops maclovinus (Patagonian blennie)
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| Brite |
KEGG Orthology (KO) [BR:emac00001]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:emac03032]
134871268 (top2a)
03036 Chromosome and associated proteins [BR:emac03036]
134871268 (top2a)
Enzymes [BR:emac01000]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
134871268 (top2a)
DNA replication proteins [BR:emac03032]
Eukaryotic type
DNA Topoisomerases
134871268 (top2a)
Chromosome and associated proteins [BR:emac03036]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
134871268 (top2a)
Centrosome formation proteins
Centriole proteins
134871268 (top2a)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
10:complement(5457504..5470421)
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| AA seq |
1583 aa
MAQPLKSFLENKPLAKTTKDPKRMSVERIYQKKTQLEHILLRPDTYIGSVEPVNQQMWVY
DEEVGLNCRDVTFVPGLYKIFDEILVNAADNKQRDKSMNCIKINIDVENNTISVWNNGKG
IPVVEHKVEKVFVPALIFGQLLTSSNYDDEQKKVTGGRNGYGAKLCNIFSTKFTVETACK
ESKKNFKQTWYDNMGRTGDSIIKPFEGEEFTCISFRPDLAKFKMTTLDRDTVALMTRRAY
DIAGASKGVRVFYNGKKIQISGFRSYVDMYLKDKLDEIGNPLTVVHEIVNDRWEVCLTMS
EKGFQQVSFTNSIATTKGGRHVDYVADQVVAKLIEVVKKKNKAGVVVKPFQVKNHMWLFV
NCLIENPTFDSQTKENMTLQQKAFGSNCPLSEKFIKMATSCGIVESIMNWVKFKAQSQLN
KKCSSVKHTKIKGVPKLDDANDAGGKNSISCTLILTEGDSAKTLAVSGLGVVGRDRYGVF
PLRGKMLNVREATLKQVMENIEINNVIKILGLQYKKNYSDPESLKSLRYGKIMIMTDQDQ
DGSHIKGLLINFIHHNWPSLLRHNFLEEFITPIIKVSHKKETISFYSIPEYNAWKDNQAN
IKSWKTKYYKGLGTSTSQEAKEYFSDMQKHRIPFKYIGPEDDEAITLAFSKKKVEERKEW
LTNFMVDRRQRRAHNLPEEFLYGQHTKSLSYNDFVNKELVLFSNSDNERSLPCLVDGLKP
GQRKVLFCCFKRNDKREVKVAQLAGSVAEMSAYHHGEVSLMMTIVGLAQNFVGSNNLHLL
QPLGQFGTRLHGGKDSASPRYIFTMLSTLTRLLFPTTDDNLLKYNVDDNQRVEPEWYIPI
IPLVLVNGSEGIGTGWASRIPNFNVQEIVNNIYRMIGGEEPLPMLPSYKGFNGTIDSLVD
NAYFVSGEVAIIDSTTIEISELPVKTWTQTYKENVLEPMMNGTEKVPPLITDYKEYHTDT
TVRFVIKMTPEKLSEAEAAGLHKVFKLQTNLTCNSMVLFDHMGSLKKYDSVIEILKDFFE
LRIKYYGLRKDWLVGMLGAEGAKLSNQARFILEKIQGTLVIENKPKKELIRMLQEMGFDS
DPVKAWKQAQEKNVEIVDEEQSEEAAEEDTSGPDFNYLLSMPMWYLSKEKKDELCKQRDT
KLAELNTLKKKSPADLWKEDLVAFCEELERVEKKEKDDAEMPVVKKGSSKAKVVKVKQET
LPTPQGRRVVPRITSTMKAEANKKADLRKGGKKVKSEDVVMKMEFGDDAENTEPSENIGL
AARLGKKTKTQAKEKGEKAASKTSKQRTLQFKAAEQKPKKNPWSDDEGADDMFDNMSDNE
MDADEAVAPRVKVERKTKVAVKYSLSDSEDEFDDLGKKSAPKRRGVISDEDSFVPEPLTD
SDMDSRAPPPKAPEPAKKTAKSKPAAKNAKAKSSSQSDDEAPAPKAPVQRKTKAAVAPKK
TAAARKPAASKKKPPVPDVSQPSILDSLTKSKPASTTAAKNFPSFDSSDSEAESKAPVTK
ARSVVKRKNAVSNSDSDSSSDLMSRLKAKATVSKKTKRWNEDESFNLSDKEAAAPVAAAA
REKPTRARKPVAYIQDSDSEDEP |
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| NT seq |
4752 nt +upstreamnt +downstreamnt
atggcccaaccactgaagagcttcctcgaaaacaagccgcttgccaagacaacaaaagat
ccgaagcggatgtctgtggagaggatctatcaaaagaagacccagttggagcacattttg
cttcgaccggacacctacatcggctctgtggagcctgtcaaccaacaaatgtgggtgtat
gatgaggaggtaggactgaactgccgcgatgtgacatttgtgcctgggctttacaagatt
tttgatgagatccttgtaaatgcagctgacaataagcagagggacaagagtatgaactgc
atcaagatcaacattgatgttgaaaacaacaccatcagtgtgtggaataatgggaagggt
attcctgtggtggagcacaaggtggagaaggtctttgtgcctgctctcatctttggacag
ctcctcacctccagtaactatgatgatgagcagaagaaagtcactggtggacgcaatgga
tatggtgctaagctttgcaacatctttagcaccaagttcactgtggagacagcctgcaaa
gagtcaaagaagaatttcaagcagacttggtatgacaacatgggcaggacaggggattct
atcatcaaaccctttgagggagaggagttcacttgcatctccttccggccggacctggcc
aagtttaaaatgaccaccctggacagagacacggtggctctgatgaccaggagggcgtac
gacatcgctggagcctccaaaggtgtccgtgtattctacaatggcaagaagatccaaatt
tcaggcttccgtagctacgtggacatgtatctgaaggacaagctggacgagatcggcaat
cccctaaccgtggtccacgagatcgtcaacgaccgctgggaggtctgcctcaccatgagt
gagaaaggtttccagcaagtcagctttaccaacagcattgccaccaccaagggagggagg
cacgtcgactatgtggctgaccaggtggtcgccaagctgattgaagtggtgaagaagaag
aataaagccggggtggtcgtcaagcctttccaggtgaagaaccacatgtggctgtttgtc
aattgcctgattgagaaccccacctttgactctcagaccaaagagaacatgaccctgcag
cagaaggcctttggatccaactgtcctctcagcgagaagttcattaaaatggccacatcc
tgtgggattgtggagagtatcatgaactgggtgaagttcaaggctcagtctcagctcaac
aagaaatgctcaagtgttaaacacaccaaaatcaaaggggtgcccaaactggacgacgcc
aacgacgcaggtgggaagaactccatcagctgcaccctgatcctcacagagggagactca
gccaagactttggctgtgtccgggctgggtgtggtcggcagggaccgatacggcgtcttc
cctctcagaggaaaaatgctcaacgtccgggaggccacgctcaaacaggtcatggagaac
atagagatcaacaacgtcattaagatcctcggccttcagtacaagaagaactacagcgac
ccggaatccctcaagtctctgcgctacggcaagatcatgatcatgacagatcaggatcaa
gatggctcccacattaagggccttttaatcaacttcatccaccataactggccatctctg
ctgcgccacaacttcctggaggagttcatcacccccatcatcaaggtgtcccacaagaag
gagacgatctccttctacagtatccctgaatacaatgcatggaaggacaaccaggccaac
atcaaatcttggaaaacaaaatactacaaaggtttgggtaccagcacatcgcaggaagcc
aaggagtacttctcggatatgcagaaacaccgcatcccgttcaagtacatcggacctgaa
gacgatgaagctatcacccttgcctttagcaagaagaaagtcgaggagaggaaagagtgg
ctgaccaacttcatggtggaccggcgccagcgcagagctcacaacctgcccgaggaattc
ctgtacggtcaacacaccaagtccctctcttacaacgactttgtcaacaaggagctggtg
cttttctccaactccgacaacgagaggtccctcccctgcctggtggacggtctgaaaccc
ggccagaggaaggtgctgttctgctgcttcaagaggaacgacaagcgcgaggtgaaggtg
gcgcagttggccggctcggtggccgagatgtcagcctatcaccatggagaggtctctctg
atgatgaccatcgttgggttggcccagaactttgtggggagcaacaacttgcacctgctg
cagcctctgggtcagtttggaaccaggttgcacggaggcaaggactctgccagccctcga
tacatcttcaccatgctcagcactctgactcgccttctcttcccaacgacggacgacaac
cttctcaagtacaacgttgacgacaaccagcgcgtagagccggagtggtacattcccatc
atccccttggtgctggtgaacggctccgaaggcatcggcaccggttgggcaagcaggatc
cccaacttcaacgtccaagagatcgtcaacaacatctaccgcatgatcggtggagaagag
cctctgcccatgcttccgagctacaaaggcttcaatggcacaattgacagcctggtggac
aacgcgtacttcgtcagtggggaggtggccatcatcgacagcaccaccatcgagatctct
gaacttcctgtcaaaacctggacgcagacctacaaggagaacgttctggagcccatgatg
aacggcacagagaaagtccctcctctgatcaccgactacaaggaataccacaccgacacc
accgtgcgctttgtgatcaagatgacccccgagaagctgagcgaggcggaggctgccggc
ctccacaaagtcttcaaactccagaccaacctcacctgcaactctatggttctgtttgac
cacatgggcagcctgaagaagtacgactctgttatagaaatactcaaggacttcttcgag
ttgaggataaagtactatggtctcagaaaggactggttggtgggcatgctgggagcagag
ggtgctaaactctccaaccaggcccgcttcatcctggagaaaatccagggcaccttggtc
atcgagaacaagccaaagaaggagctgatccgcatgctgcaggagatgggcttcgactcg
gacccagtgaaggcttggaaacaggctcaggagaagaatgtggaaattgtggatgaggag
caaagcgaggaagcagcggaggaggacaccagcgggccggacttcaactacctgctgagc
atgcccatgtggtacctgagcaaagagaagaaggatgagctttgcaaacagagggacacc
aagttggcagagctcaacaccctgaagaaaaagagtccagcagacctgtggaaggaagac
ctggttgctttctgcgaggaactggagagggtcgagaaaaaggaaaaggacgatgccgaa
atgcccgtggttaaaaaggggagcagcaaagcgaaggtggtgaaggtgaaacaggagact
ctgcccacgccgcagggccgccgcgtggtcccgcgcatcaccagcaccatgaaagctgaa
gccaacaagaaggccgatctgaggaaggggggcaaaaaagtcaagagcgaggacgtcgtg
atgaagatggagttcggagacgatgcagagaacaccgagccaagcgagaacatcggcttg
gctgcacgactgggcaagaaaaccaaaacccaggcaaaggaaaagggggagaaagctgca
tcaaagaccagcaagcagcgcactcttcagttcaaggctgctgagcagaagcccaagaag
aacccgtggtcggatgatgagggggcggacgacatgtttgacaacatgtccgacaacgaa
atggatgcggatgaagcggtcgcccccagggtgaaggtcgaacgcaaaaccaaagttgcg
gtgaagtacagcttgtccgacagtgaagatgagtttgatgacttgggaaagaagagcgct
cctaaacgcagaggcgttatcagtgatgaggatagctttgtcccggagccactgaccgac
agcgacatggactctcgagccccgcctccaaaagctccagagcctgcgaagaaaacggcc
aaaagcaaaccggcagctaaaaatgctaaagccaagtccagctctcagtcagatgatgag
gcacctgctcccaaagctccggttcaacgtaaaaccaaggcagccgtcgcgcccaagaaa
actgctgctgccagaaagccggccgcatccaagaagaagcctccagtgccagatgtgagt
cagccatccatcctggattctctcaccaaatccaaacctgcatcgaccaccgccgccaag
aacttcccgtcatttgactccagtgactcggaggctgagtccaaagctccagttacaaag
gcaaggtccgttgtcaagaggaaaaacgccgttagcaacagcgactccgacagctcgagc
gacctcatgtcccgtctgaaggctaaagcaaccgtcagcaagaaaaccaaaaggtggaat
gaggacgagagcttcaatctttcagacaaggaagcagcggctccagtcgccgcggcagca
cgagagaagcccacgcgtgcccgcaagcctgtcgcctacatacaggactcggactcagag
gacgagccttaa |
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