Eublepharis macularius (Leopard gecko): 129324816
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Entry
129324816 CDS
T09084
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
KO
K05858
phosphatidylinositol phospholipase C, beta [EC:
3.1.4.11
]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc00562
Inositol phosphate metabolism
emc01100
Metabolic pathways
emc04020
Calcium signaling pathway
emc04070
Phosphatidylinositol signaling system
emc04081
Hormone signaling
emc04082
Neuroactive ligand signaling
emc04261
Adrenergic signaling in cardiomyocytes
emc04270
Vascular smooth muscle contraction
emc04310
Wnt signaling pathway
emc04371
Apelin signaling pathway
emc04540
Gap junction
emc04621
NOD-like receptor signaling pathway
emc04912
GnRH signaling pathway
emc04916
Melanogenesis
Module
emc_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
129324816 (PLCB2)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
129324816 (PLCB2)
04371 Apelin signaling pathway
129324816 (PLCB2)
04020 Calcium signaling pathway
129324816 (PLCB2)
04070 Phosphatidylinositol signaling system
129324816 (PLCB2)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
129324816 (PLCB2)
04081 Hormone signaling
129324816 (PLCB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04540 Gap junction
129324816 (PLCB2)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
129324816 (PLCB2)
09152 Endocrine system
04912 GnRH signaling pathway
129324816 (PLCB2)
04916 Melanogenesis
129324816 (PLCB2)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
129324816 (PLCB2)
04270 Vascular smooth muscle contraction
129324816 (PLCB2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
emc04131
]
129324816 (PLCB2)
Enzymes [BR:
emc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
129324816 (PLCB2)
Membrane trafficking [BR:
emc04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
129324816 (PLCB2)
Endocytosis
Macropinocytosis
Phospholipase C
129324816 (PLCB2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PLC-beta_C
PI-PLC-X
PH_14
PI-PLC-Y
PLCB1-4-like_EFh
C2
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
129324816
NCBI-ProteinID:
XP_054828198
UniProt:
A0AA97KSG9
LinkDB
All DBs
Position
2:complement(64539075..64632489)
Genome browser
AA seq
1232 aa
AA seq
DB search
MSVLSPILMPPEVKEYLTKGERFIKWDDDTTNASPVILRVDPKGFYLYWTFQSKETDFLD
ITSIRDTRVGKFAKIPKSQKLREVFNLDFPDNNFLLKTLTVVAGPDMVDLTFHNFVSYKE
NVGKSWADDILAIARNPFTYNASRYSFLEKILLKLKLQLNADGKIPVKNIFQMFPADRKR
VEAALSACHLPKGKNDGINPEDFPETVYKSFLMSLCPRPEINEIFTSHHSKAKPYMTKEH
LTKFINKKQRDSHLNDVLFPPAKPEQVQGLIEKYESSGMNVQRGQLSPEGMVWFLCGPEN
SVILQDKLLLYQDMNQPLSHYFINSSHNTYLTAGQFSGISSPEMYRQTLLAGCRCVELDC
WKGKPPDEEPIITHGFTMTTEILFKDAIEAIAESAFKTSPYPVILSFENHVDSPKQQAKM
AEYCRTIFGDMLLTDPLEKFPLKPGVPLPSPQDLLGKILIKNKKNQFPPGENQDTLKKGR
GPEEEAAEQLTTVDRDSTARADEATEEVPKVEEDLQNLNEEEIKKLQSDEGTAGLEVTAY
EEMSSLVNYIQPIKFDTFEISAQKNRSYVISSFTETKAYELLSKSSIQFVDYNKRQMSRI
YPKGTRMDSSNYMPQMFWNVGCQMAALNFQTTDAAMQQNLALFEFNGQSGYLLKHDFMRR
PDKQFDPYSVDRIDVVVASTLSITIISGQFLSERSVRSYVEVELFGLPGDPKRRYRTKLT
PTANSINPVWKEEAFVFEKIMMPELASLRIVVLEEGGKFIGQRIIPITAVCSGYHHICLR
SEANMPLNLPSLFVYVEMKDYVPDSWADMTMALCNPIKFFSAQDKKSTKTQEADMEKPGL
QKGLSTTQLNTNGLPNASGTISIPPSNGSAGKIDTVASCQLFFLQGTSARGKEETTKEPA
KNPTVPQTASIEELQQMKMFGKLLKKQEKELKELERKASKRREDLLQKYTFLFTELAVQA
GKKKTLCPTKSQKKKSCRSLTLDEMTAGRNTAERAESPGHRVLALKEKLEEELLQLGEEH
YDGIRKKKEQHAAEQIAKMIELAKEKQACELKALKDSSESYNKELKKKLEVKRIDRIQAV
AKNASDRSAQERLKREINCTHIQEVVQQIKQLNEKQAKYQQVLETKQTDCLEKIKGRETQ
LHQEALGEYEEKVKALNAEVQDLVKNCIKVCFPLEAEVAKEEVLNAADEGDERLKPQLQE
NDLVLESVQLKTQTAENYLEFEESTDTQCSRL
NT seq
3699 nt
NT seq
+upstream
nt +downstream
nt
atgtcggtgctcagccctatcctgatgccccctgaggtgaaggagtacctgaccaaggga
gaacgctttatcaagtgggatgatgataccacaaatgcttctcctgtgattctgcgggtt
gacccaaagggtttttatctatattggaccttccagagtaaggaaacagattttttggat
ataacaagtattcgagatactagagtagggaaatttgccaagattcctaagagccagaag
ctccgggaggttttcaatctggattttccagacaacaacttcttgctcaagacattgact
gtggttgctggtcctgatatggtggacctcacctttcataattttgtctcctataaagaa
aatgtcggaaagagttgggcagatgatatcttagccattgctaggaacccatttacatat
aatgcttctcgttacagcttcctggaaaaaatactgctgaaactgaagttgcagttgaat
gctgatgggaaaattccagtcaagaatatttttcagatgtttcctgcagacagaaaaagg
gtagaagctgcattaagtgcgtgtcatcttccaaaggggaagaatgatggcatcaatcct
gaggacttccctgagactgtgtacaaatcattcttgatgagcctgtgtcctcggccagag
attaatgaaatattcacctcacaccattcaaaagccaagccctacatgaccaaagaacac
ttgacaaaatttatcaacaagaaacagcgagattcccacctcaatgatgtgcttttcccc
cctgccaagccagagcaagtgcagggtctcatagaaaaatacgagtccagtgggatgaat
gttcagagagggcagctatctccagaggggatggtttggttcttgtgtggtcctgaaaac
agtgtgatattacaggacaaactactgctgtaccaggatatgaaccagccactctctcac
tattttatcaactcatcccataacacctatctaacagctgggcagttttcgggaatctca
tctccagagatgtatcgccagacccttttggctggttgccgctgtgtggaacttgactgc
tggaaagggaagcctccagatgaggagcccatcatcacacatgggttcacaatgaccact
gaaatactgttcaaggatgcaattgaagctattgcagaaagtgctttcaaaacctccccc
taccctgtgatcttatcctttgagaatcatgtggactcgcccaagcagcaggctaagatg
gcggaatactgcagaaccatatttggggatatgctgctgacagatccactggaaaaattc
ccactcaaaccaggggttccactgccaagcccccaggatctcttggggaaaatcttgatt
aagaacaagaagaaccagttcccacctggggagaaccaagacaccttgaagaaagggagg
ggtccagaggaggaagctgctgaacagctcacaacagtggacagagatagcacagccagg
gcagatgaggcaactgaagaggtgcccaaagtggaggaggacctgcagaacctgaatgaa
gaagagattaaaaagctgcagtctgatgagggtactgcaggtctggaagtgaccgcttat
gaagaaatgtccagcttggttaattatattcagcccatcaaatttgacacgtttgaaatc
tcagcacagaagaatagaagttatgtcatttcctctttcactgagacgaaggcttatgaa
ctattgtccaaatcttccatccagtttgtagattataacaagaggcagatgagccgaatt
tatcccaagggcacccgtatggattcttcaaactacatgcctcagatgttctggaatgtt
ggctgccaaatggcggccttaaacttccagacaacagatgccgccatgcaacagaacctg
gccctctttgaattcaatgggcagagtggctacctcctcaaacatgacttcatgcgccgg
ccagataagcaatttgacccttactctgtggaccgcattgatgtagtggtggcaagcaca
ttgtcaataacgataatttctggccagtttctctcagagcgcagtgtgaggtcctatgta
gaagtggagttgtttggcctgccaggtgatcccaaacgccgatacagaaccaagctgaca
ccaactgcaaactcaattaatcctgtatggaaggaggaggcttttgtatttgaaaagatt
atgatgccagagttggcgtctctcagaattgtggttttggaggaaggcggaaagttcatt
ggtcagcgcatcattcccatcactgctgtatgttcaggctatcaccacatttgccttcgt
agtgaggccaacatgccacttaatctgccttctctcttcgtttatgtggagatgaaagac
tatgttcctgactcatgggcagatatgaccatggccctctgcaacccaatcaaatttttt
agtgcacaggacaaaaagtcaaccaagacccaagaggctgatatggagaagcccggctta
caaaaaggcctttctactactcagctcaataccaatggactacccaatgcctctggcacc
ataagtatccctccttcaaatggatctgcaggcaaaatagatacagtagcatcatgtcag
ttgtttttcctccaaggaacttcagcaagaggaaaagaagaaaccacaaaggaacctgca
aaaaaccctacagtgccccagacagctagcatcgaggagctgcagcagatgaagatgttt
ggaaaactgttgaagaagcaagagaaagagctgaaggagctggagcggaaggcaagcaag
cgaagggaagatctgcttcaaaaatacaccttccttttcactgaactggctgtccaggct
ggcaagaagaaaacactgtgcccaacaaaatctcagaaaaagaaaagttgcaggagctta
accttagatgagatgactgcaggaaggaacactgcagagagggccgagagccctggccac
agagtcttggcgctgaaggaaaagctggaggaagagctgctgcagctgggagaagaacac
tatgacgggattcggaagaagaaggagcagcatgctgcagagcaaattgctaaaatgata
gaacttgcaaaagaaaagcaagcatgtgagctgaaggcactgaaggattcttctgaaagt
tacaataaagagttgaagaagaaactggaggtcaagagaatagaccgaatccaagccgtg
gctaagaatgccagtgacaggagtgctcaggaaaggttaaagagagaaatcaactgcaca
catattcaagaagtggtacagcagatcaaacagttgaatgaaaagcaggccaagtatcaa
caagtcctggaaacaaagcagacagactgccttgagaaaattaaaggaagagaaacccag
ctccaccaggaagctttgggagagtatgaggagaaggtgaaagccctcaatgcagaggtg
caggacttagtgaagaactgcatcaaagtctgtttccctctagaagctgaagtggccaaa
gaagaggtcctcaatgctgctgacgagggagacgagaggctgaagccacaactgcaagaa
aacgacctggtgctcgagtctgtacagcttaaaactcagacggcagagaattatttagaa
tttgaggaatccactgatactcagtgcagcagattgtaa
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integrated database retrieval system
