Eublepharis macularius (Leopard gecko): 129326725
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Entry
129326725 CDS
T09084
Symbol
PLCB1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
KO
K05858
phosphatidylinositol phospholipase C, beta [EC:
3.1.4.11
]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc00562
Inositol phosphate metabolism
emc01100
Metabolic pathways
emc04020
Calcium signaling pathway
emc04070
Phosphatidylinositol signaling system
emc04261
Adrenergic signaling in cardiomyocytes
emc04270
Vascular smooth muscle contraction
emc04310
Wnt signaling pathway
emc04371
Apelin signaling pathway
emc04540
Gap junction
emc04621
NOD-like receptor signaling pathway
emc04912
GnRH signaling pathway
emc04916
Melanogenesis
Module
emc_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
129326725 (PLCB1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
129326725 (PLCB1)
04371 Apelin signaling pathway
129326725 (PLCB1)
04020 Calcium signaling pathway
129326725 (PLCB1)
04070 Phosphatidylinositol signaling system
129326725 (PLCB1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04540 Gap junction
129326725 (PLCB1)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
129326725 (PLCB1)
09152 Endocrine system
04912 GnRH signaling pathway
129326725 (PLCB1)
04916 Melanogenesis
129326725 (PLCB1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
129326725 (PLCB1)
04270 Vascular smooth muscle contraction
129326725 (PLCB1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
emc04131
]
129326725 (PLCB1)
Enzymes [BR:
emc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
129326725 (PLCB1)
Membrane trafficking [BR:
emc04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
129326725 (PLCB1)
Endocytosis
Macropinocytosis
Phospholipase C
129326725 (PLCB1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PH_14
PI-PLC-Y
PLC-beta_C
EF-hand_like
DUF1154
Motif
Other DBs
NCBI-GeneID:
129326725
NCBI-ProteinID:
XP_054831010
UniProt:
A0AA97J3U6
LinkDB
All DBs
Position
1:complement(13702590..14401401)
Genome browser
AA seq
1218 aa
AA seq
DB search
MAGAQPGVHALQLRPVCVSASLKKGAAFAKWDDDSTSVTSVFLRTDPQGFFLYWTDQNKL
QETELLDVSIVKDARFGKHARAPKDPKLREHLEGGNVGGRLENRMLTIVYGPDLVNISYL
NLVAAQEDIAKVWAEEVFSLATNLLAQNMSREASLQKAYTKLKLQVTTEGRIPLKNIYRL
FSTDRKRVETALEACNLPSARNDSIPQEDFTPEVYREFLSNLCPRPEIDHIFVEYGAKTR
PYLTVDQMMEFINLKQRDPRLNEILYPPLKQEQVQQLTEKYEPNKSLAKKGQISVDGFMN
YLSGEENGVVPPEKLDLNEDMTQPLSHYLINSSHNTYLTAGQLAGNSSVEMYRQVLLSGC
RCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDS
PKQQAKMAEYCRLIFGDALLMEPLEKYPLERGIPLPSPADLMYKILVKNKKKSHKSADGS
AKKKLAEQASNACSDASSGFEPSSPGAGEAEIESDDDDDFDDDCKKSSMDEGTAGSEAMA
TEEMSNLVNYIQPVKFESFETSKKRNKSFEMSSFVETKALEQLTKSPVEFVEYNKMQLSR
IYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLSMQINMGMYEYNGKCGYRLKPEFMR
RPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYAEVDMFGLPVDTRRKALKTK
TSQGNAVNPVWEDEVIVFKKVVLPSLACLRIAVYEEGGKFIGHRILPVSAIRPGYHYISL
RNERNQPLMLPALFIYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRANQLAALTLEDEE
EVKKEADQGDLPSEAQNEPKPAPAENGVNYTTSLTPKPSTQVVPSQPAPSSVKVPAKTED
LIQSVLTEVEAQTIEELKQQKAFVKLQKKHYKEMKDLVKRHHKKTTDIIKEHTAKYNEIQ
NDYMRRRMVLEKAAKRDNKKKGETASPDHGSSTVEQELTALDSEMTQKLIELKEKQQQQL
LNLRQEQYYSEKYQKQAHIKLLIQKLTDVAEECQSSQLKKLKEICEREKKELKKKMDKKR
QEKITESKSKDKNQVDEEKTEMIRSYIQEVVQYIKRLEDAQSKRQERLVEKHKEIRQQIL
DEKPKLQAELEQEYQDKFKRLPLEILEFVQEAMKGKISEDGDHSSTPSLASDGGKQNHKP
LQNEEPEDNPGKEFDTPL
NT seq
3657 nt
NT seq
+upstream
nt +downstream
nt
atggccggggcgcagccaggggtccacgctctccagctgcggccggtctgcgtctccgcc
agcctcaagaagggcgccgccttcgccaagtgggacgatgactccacaagtgtgacatca
gtttttcttcgaacggacccacaaggatttttcttgtattggacagaccaaaataagttg
caggagacagagctgttagatgtcagcattgttaaagatgccaggtttgggaaacatgcc
agagctcctaaggacccgaaactacgtgaacatctggaaggagggaatgttggaggaaga
ctggagaaccgaatgcttacaattgtgtatggccctgacctagtcaatatatcatacttg
aatttagtagctgctcaagaagacatagcaaaggtatgggcagaagaagtcttcagtttg
gctaccaacttgctggcacagaacatgtcgagagaagcttctctgcaaaaagcttacaca
aagctcaagctgcaagtcacaacggagggacgtatccctttgaagaacatttatcgcttg
ttctccacggacagaaagcgtgttgagacggcgctggaagcttgcaaccttccttctgcc
aggaatgattcaattcctcaagaggacttcaccccggaagtatacagagagttcttgagc
aacctgtgtcctcggcctgaaattgatcacatcttcgtagagtatggtgccaagaccaga
ccgtatcttactgttgaccagatgatggaatttataaacttgaagcaacgagacccacgc
ttaaatgaaattctctatccacctttgaagcaagaacaggttcaacagctgactgagaaa
tatgaacccaataagagtctggctaagaaagggcagatatcagtggatggatttatgaat
tacttgagtggagaggagaatggagtggttcctcctgaaaaactggatttgaacgaagat
atgacccagcctctgtcgcactatttgatcaactcctcgcataacacctacctcacagct
ggacagctagctggtaactcttccgtggagatgtatcgccaagtgctattgtccggctgc
cgctgtgttgagttggactgctggaaaggccgaacggctgaagaggagccagtcatcaca
cacgggtttaccatgacaactgaaatatcgtttaaggaagtcatagaagctattgctgaa
tgtgcatttaagacatcgccttttcccatcctcctttcatttgaaaatcacgttgattct
cctaaacagcaggcaaaaatggcagaatattgcagattaatatttggcgatgctttgctg
atggagccactggaaaaatatccacttgaacgtggcattccccttccaagtccggctgac
ctgatgtacaaaatcctggtgaagaataaaaaaaagtcccacaagtctgcagatggtagt
gctaagaagaagctcgcagaacaggcttcaaatgcatgcagcgatgcctcgagtgggttt
gagccctcatctcctggagcaggggaagcagagatagagagcgacgatgatgatgacttc
gatgatgactgcaaaaaatcatcaatggacgaaggaacagctggaagtgaggccatggct
actgaagaaatgtccaacttggtgaattatatacagcctgtgaagtttgaatcatttgag
acatctaaaaaacggaacaagagttttgaaatgtcttcctttgtggaaaccaaagcactg
gagcagctcacaaaatcccctgttgagtttgtggagtataacaaaatgcagctgagtcga
atttatccaaaagggacgcgtgtggattcatcaaattacatgccccagctgttttggaat
gcaggctgtcagatggttgctctgaatttccaaactgttgatttgtctatgcaaataaat
atgggcatgtatgaatataatggcaaatgtgggtacagactaaaaccagagttcatgaga
agaccagacaaacatttcgacccctttactgaaggcattgtggatggaatcgtagcaaac
actttgtccgtgaagattatttctggacagttcctttctgataaaaaagttgggacttac
gcagaggtggacatgttcggtctgcctgtggatacaaggcggaaagctctcaagaccaag
acctcccaaggcaatgctgtaaatcctgtatgggaagatgaagtcatagtgtttaagaag
gtggttttgccttccctagcatgcctgaggatagcagtatatgaagaaggagggaaattc
attggtcatcggatattgccggtttcagcgattcgaccaggttatcactacatctccctg
aggaatgagaggaatcagcccttgatgctgccagccttattcatatacatagaggttaaa
gactatgtacccgatacttatgcagatgttatcgaagcattatccaacccaatccgatat
gtgaacttaatggagcagagagcaaaccagttggcagctttgactctggaggatgaagag
gaagtcaaaaaagaggctgatcagggagatttgccttcagaagcccagaacgaaccgaag
cctgcaccagctgaaaatggagtaaactacaccacttccctcacccctaaaccatccact
caggttgttcccagccaaccagcaccaagttctgtgaaagtgccagcaaaaacggaagat
cttattcagagcgtcctgacagaagttgaagcacaaacaattgaggagctgaaacagcag
aaagcctttgtgaaacttcagaagaagcactacaaagaaatgaaggatcttgtgaagaga
caccacaaaaaaaccactgatatcataaaagagcatactgcaaaatacaatgaaatccaa
aatgattacatgcgacggagaatggttttggagaaagcagctaaaagggacaataagaaa
aaaggtgagacggccagtcctgaccacggctcttcgaccgttgagcaagagttgactgct
ctggattcagaaatgacccagaagttgatagaacttaaggaaaagcaacagcaacagctt
ctgaatctgcgacaagaacagtattacagcgaaaagtaccagaagcaggcgcacattaaa
ctgctcattcaaaagctgacagatgttgccgaggagtgccaaagcagtcagttaaagaaa
ctgaaagagatctgtgaaagagaaaagaaagagttgaaaaaaaagatggacaagaagagg
caagagaaaatcacagaatctaaatcaaaggataaaaatcaggtggacgaggagaagaca
gaaatgattcgatcatatattcaggaggtcgtacagtacattaaaaggcttgaagatgct
cagagtaaaaggcaggaaagacttgtggagaagcacaaggagatccgccagcaaatactg
gacgaaaaacccaagttacaggctgaacttgagcaagaataccaagacaaattcaaaaga
ctcccgctggaaattctggaatttgtacaggaagcaatgaaaggcaaaattagcgaagat
ggagaccacagctctaccccttctttggcatctgatggtgggaagcagaaccataaacca
ttgcaaaacgaagagccggaagataatccagggaaagaatttgatacccctctctaa
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