Eublepharis macularius (Leopard gecko): 129331860
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Entry
129331860 CDS
T09084
Symbol
PIK3CA
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1
KO
K00922
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:
2.7.1.153
]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc00562
Inositol phosphate metabolism
emc01100
Metabolic pathways
emc04012
ErbB signaling pathway
emc04068
FoxO signaling pathway
emc04070
Phosphatidylinositol signaling system
emc04081
Hormone signaling
emc04140
Autophagy - animal
emc04150
mTOR signaling pathway
emc04210
Apoptosis
emc04218
Cellular senescence
emc04370
VEGF signaling pathway
emc04510
Focal adhesion
emc04620
Toll-like receptor signaling pathway
emc04625
C-type lectin receptor signaling pathway
emc04810
Regulation of actin cytoskeleton
emc04910
Insulin signaling pathway
emc04914
Progesterone-mediated oocyte maturation
emc05100
Bacterial invasion of epithelial cells
emc05132
Salmonella infection
emc05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
129331860 (PIK3CA)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
129331860 (PIK3CA)
04370 VEGF signaling pathway
129331860 (PIK3CA)
04068 FoxO signaling pathway
129331860 (PIK3CA)
04070 Phosphatidylinositol signaling system
129331860 (PIK3CA)
04150 mTOR signaling pathway
129331860 (PIK3CA)
09133 Signaling molecules and interaction
04081 Hormone signaling
129331860 (PIK3CA)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
129331860 (PIK3CA)
09143 Cell growth and death
04210 Apoptosis
129331860 (PIK3CA)
04218 Cellular senescence
129331860 (PIK3CA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
129331860 (PIK3CA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
129331860 (PIK3CA)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
129331860 (PIK3CA)
04625 C-type lectin receptor signaling pathway
129331860 (PIK3CA)
09152 Endocrine system
04910 Insulin signaling pathway
129331860 (PIK3CA)
04914 Progesterone-mediated oocyte maturation
129331860 (PIK3CA)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
129331860 (PIK3CA)
09171 Infectious disease: bacterial
05132 Salmonella infection
129331860 (PIK3CA)
05100 Bacterial invasion of epithelial cells
129331860 (PIK3CA)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
emc04131
]
129331860 (PIK3CA)
Enzymes [BR:
emc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
129331860 (PIK3CA)
Membrane trafficking [BR:
emc04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
129331860 (PIK3CA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3Ka
PI3_PI4_kinase
PI3K_rbd
PI3K_C2
PI3K_p85B
DUF2321
ABC1
Retrotran_gag_4
Ribosomal_S15
Motif
Other DBs
NCBI-GeneID:
129331860
NCBI-ProteinID:
XP_054838454
UniProt:
A0AA97JJN8
LinkDB
All DBs
Position
6:complement(16815676..16868324)
Genome browser
AA seq
1068 aa
AA seq
DB search
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNIESSPELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
NFTMPSYSRRISTATPYMNGEASAKSLWVINSNLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLQYEMHILDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMSVIEEHANWTISRELGYNYSPAGQSSRIARDNELSESDKEQLHAICTRDPL
SEITEQEKDFLWRHRHYCLNTPEILPKLLLSVKWNSRDEVAQMYCLIKDWPAIKPELAME
LLDCNYPDRMVRAFAVRCLEIYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHALHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
NT seq
3207 nt
NT seq
+upstream
nt +downstream
nt
atgcctccaagaccatcatctggtgaattgtggggcatccacttgatgccccctagaatc
ctagtggaatgtcttctacctaacggtatgatcgtgactttagaatgcctccgtgaggcc
acattgttaaatattaaacatgaactctttaaagaagctagaaagtatcctctctaccag
ctccttcaagatgagtcatcttacattttcgtaagtgttacccaagaagcagaaagagaa
gaatttttcgatgaaactcggagactatgtgacctacggctctttcagccttttctaaaa
gtcatagaaccagtaggcaacagagaagagaaaattctgaatcgtgaaattggttttgct
attggcatgcctgtctgtgaatttgacttggttaaagatccggaagttcaggacttcaga
agaaatattctcaatgtctgtaaagaagcagttgatcttcgagatgctaatgcaccccat
agtagagcattatatgtctgcccccccaacatagaatcgtcgcccgaattgcccaagcat
atatacaataaactagataaagggcaaataatagtagtaatctgggtaatagtctctcct
aataatgacaagcagaaatacaccttaaaaatcaatcatgactatgtgccagagcaagta
atcgcagaagcaatcaggaaaaaaactcgaagcatgttactatcatcggaacagctaaag
ttatgtgttttggagtatcaaggaaagtatattttaaaagtatgtggttgtgatgaatac
ttgctagaaaaacatcccctcagtcagtataagtacatccgaagttgtatcatgcttggt
cgaatgcccaacctcatgctgatggcaaaggaaagtctttacactcagctgccattggat
aactttacgatgccatcttattccaggcgcatctctacagctacgccatacatgaatggt
gaagcttcagccaaatctctctgggttattaacagtaatctcagaataagaatcctctgt
gctacctatgtaaatgtaaatattcgtgatattgacaagatctatgtccgaactggtatt
taccatggaggagaaccattgtgtgataatgtgaatactcagcgagtaccttgctccaat
cccagatggaatgaatggctgcagtatgaaatgcatattcttgatcttccacgtgctgct
cggctttgtctttctatctgctcagttaaggggagaaagggtgcgaaggaggagcactgc
ccattggcgtgggggaatattaatatgtttgattacacagacactcttgtttctggcaaa
atggctttgaatttgtggcctgtacctcatggtctggaagacctgctaaatcccattgga
gtcaccggatcaaatccaaataaggaaactccctgtttagagctggaatttgattggttt
agcagtcctgtaaagttccctgacatgtcagtgattgaagaacatgctaattggactatc
tctcgagaactagggtataactacagtcctgctgggcagagcagtagaatagctagagac
aacgaactaagcgaaagtgacaaagagcagctccatgcaatttgcactcgagatcccttg
tctgaaataactgaacaggaaaaggatttcctttggagacacaggcattattgtttaaat
acaccagaaattctgcctaagctccttttgtctgttaagtggaactctagagatgaagta
gcccagatgtactgcttgatcaaagactggcctgccatcaaacccgaactggcaatggaa
cttttggactgcaactaccctgaccggatggtgcgcgcttttgcagtgcggtgtctggaa
atatacttgacagatgacaagctgtctcagtatttgattcagctggtgcaggttctaaaa
tatgagcagtacttggataatctgttggtaagatttttactgaagaaggcactgaccaat
cagagaataggacatttcttcttttggcatctaaagtctgaaatgcacaataaaaatgtg
agccagaggtttggcctgcttttggaatcctattgccgagcatgtgggatgtacctaaaa
catctgagcaggcaggtagaagctatggaaaaactgattaacctcacagacatcctcaaa
caggagaaaaaggatgaaacgcaaaaggtacagatgaagttccttgtggagcaaatgagg
cggccagacttcatggatgcattgcaaggttttatatctcctctcaatcctgctcatcag
cttggaactcttaggctcgaggagtgcaggattatgtcatctgcaaaaaggccactgtgg
cttaattgggaaaacccagatattatgtctgagctgctatttcagaacaatgagatcatc
ttcaaaaacggggatgatctgcgccaggatatgctcacacttcagatcattcgaattatg
gaaaacatctggcaaaatcaaggccttgatctcaggatgcttccttatggttgtttatct
attggtgactgtgtgggactcattgaggttgtgagaaattcacacacaatcatgcaaatc
cagtgcaaaggtggccttaaaggcgcactgcagttcaacagtcatgcattacatcagtgg
ctcaaagacaagaacaaaggagaaatgtatgatgcagctattgatttgtttacacgctct
tgtgctggttattgcgtagcgactttcatactgggaattggcgatcgccacaatagcaat
atcatggtgaaagatgacgggcagctgtttcacatagattttggacatttcttggatcac
aagaaaaagaagtttggatacaaacgtgagcgggtcccctttgtcttaacgcaagatttc
ttgatagtgattagtaaaggagcccaagaatgtactaaaactagggaatttgaaaggttt
caagaaatgtgttacaaggcttatttagcaatccggcagcatgccaatctcttcataaac
ctcttctccatgatgcttggttcaggaatgccagagctacagtcttttgatgacattgca
tatattcggaagacacttgcattggacaaaacagagcaggaagcacttgagtatttcatg
aagcagatgaacgatgctcatcatggcggatggacgacaaaaatggactggatcttccat
acaatcaagcaacatgctttgaactga
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