Eublepharis macularius (Leopard gecko): 129334326
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Entry
129334326 CDS
T09084
Symbol
GNE
Name
(RefSeq) bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1
KO
K12409
bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:
3.2.1.183
2.7.1.60
]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc00520
Amino sugar and nucleotide sugar metabolism
emc00541
Biosynthesis of various nucleotide sugars
emc01100
Metabolic pathways
emc01250
Biosynthesis of nucleotide sugars
Module
emc_M00955
CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
129334326 (GNE)
00541 Biosynthesis of various nucleotide sugars
129334326 (GNE)
Enzymes [BR:
emc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.60 N-acylmannosamine kinase
129334326 (GNE)
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
129334326 (GNE)
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GFIT
Motif
Pfam:
Epimerase_2
ROK
Hexokinase_1
DRTGG
FGGY_N
Glucokinase
Motif
Other DBs
NCBI-GeneID:
129334326
NCBI-ProteinID:
XP_054842304
UniProt:
A0AA97JSV1
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Position
8:136688382..136747817
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AA seq
755 aa
AA seq
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MGSNAPLRWEQASPRGPHELYFKNLSKQKQKRVMEKHGNNRKLRVCVATCNRADYSKLAP
IMFGIKAEPQFFELDVVVLGSHLIDDYGNTYRMIEQDDFDIHTRLHTIVRGEDEAAMVES
VGLALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIR
HAITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSVIRMWIGE
DVKPKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKKTLVLFPNIDAGSKEMVRVMRK
KGVEHHPNFRAVKHVPFDQFIQLVAHAGCVIGNSSCGVREVGAFGTPVINLGTRQIGRET
GENVLHVRNADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLGEPLQKKF
CFPPVKENISQDIDHILETQSALAVDLGGTNLRVAIVSMKGEIVKKYSQLNPKTYEDRIK
LILKMCVEAASEAVNLNCRILGVGISTGGRVNPREGVVLHSTKLIQEWSAVDLRTPISDT
LHLPVWVDNDGNCAALAERKFGHGKGVENFVTLITGTGIGGGIIHQNELIHGSSFCAAEL
GHIMVALDGPECLCGSHGCIEAYASGIALQREAKKLHDEDSLFVEGMSVKKEETVTAAHL
IQAAKLGNPKADHIIRTAGTALGLGVVNILHTINPSLVILSGVLASHYVGVVKDMIHQRA
LFSVQTVDVVVSDLVDPALLGAASMVLDYTTRRIY
NT seq
2268 nt
NT seq
+upstream
nt +downstream
nt
atgggcagcaacgcgcctctgcgctgggagcaggcgagtccccgcggtccccacgagctt
tatttcaagaacctgtcgaaacagaaacaaaagcgagtaatggagaagcatgggaacaac
cggaagctccgggtttgtgttgctacttgcaatcgggctgattactccaagttggccccg
atcatgtttggcattaaagcggaaccgcagttctttgagctggatgttgtggttctggga
tctcacctaatagatgactacggtaacacttaccgtatgattgagcaagacgattttgac
atccacaccagactgcacacaatagtgcgaggagaagatgaggcagccatggtggagtct
gtgggtctggccttagtcaagctcccggatgtactcaaccgcctgaaacccgacatcatg
atcgtccacggtgacagatttgatgctctggcactggcgacatctgcagccctaatgaac
attcggattcttcacattgaaggtggagaagttagtgggaccattgatgactccattagg
cacgcgataaccaagttagctcattaccatgtgtgttgcacgagaagtgccgagcagcac
ttgatatccatgtgtgaagatcatgaccgtatcctcctggcaggctgtccttcgtacgat
aagctgctgtctgccaaaaataaggactacatgagcgttatccgcatgtggataggtgag
gatgtgaaaccaaaagattacatagttgctttacagcatcctgtgaccacagacattaaa
cattccataaagatgtttgaactgacattagatgcccttatctccttcaacaagaagacc
ttggttttattcccaaatattgatgctgggagcaaagaaatggttcgtgtaatgaggaag
aagggtgttgagcatcacccaaattttcgagcagtaaagcatgttccatttgaccagttc
attcagcttgtggctcatgctggttgtgtgattggaaacagcagttgtggtgtgcgagaa
gttggggcgtttggaacccctgtcatcaatctgggaacacgccagatagggagagaaaca
ggggaaaatgtccttcatgttcgtaatgctgacacccaagacaaaatactgcaagccttg
catctccagtttggcaaacaatatccttgttcaaagatatatggagatggaaatgctgtt
ccaagaatcctaaagttcctcaagtctattgaccttggagaacccctacagaagaaattc
tgcttccctcctgtcaaggaaaacatctcccaagatattgaccatatcttggaaacccag
agtgcgttggcagtggatctgggtggaacaaacctccgggtagcaatagtcagcatgaag
ggtgaaatagttaagaaatatagccaactgaaccccaaaacctatgaggacagaataaaa
ttgatccttaagatgtgtgtagaggctgcctcagaagcagtaaatctgaattgcagaatt
ctgggtgtgggcatttctacaggtggccgagtcaatccccgagaaggtgttgttcttcat
tccacaaaacttattcaggaatggagcgctgttgatctgcgaactccgatatcggacacc
ctgcacctgccagtatgggtggacaatgatggcaactgtgctgctttggcagagagaaaa
tttggacatggaaaaggagtggaaaactttgtaacactcatcactgggacaggtatcggt
ggaggaatcattcaccaaaatgaattgatccacggaagttctttttgtgctgctgaactt
gggcatatcatggtagctttggatggtcctgaatgtctttgtgggagccatggctgtata
gaggcatatgcttccggaatagccttgcagagagaagctaaaaaattgcatgatgaggat
tcattgttcgtggaagggatgtctgtaaagaaggaagagacagtaactgctgcacatctc
attcaggcagctaaactgggaaatccgaaagccgaccacatcattagaacagcgggaact
gctctgggccttggagttgtgaacattctgcacaccattaatccctcgcttgtgatcctt
tctggagtcttggcaagtcactacgtcggtgtggtcaaagatatgatccatcagcgggcc
ttgttctctgtgcagacagtggacgtggttgtctcagacctggtggatcctgccttgctt
ggggctgctagcatggtcctagattatactacacgcaggatatattag
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