Eublepharis macularius (Leopard gecko): 129334461
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Entry
129334461 CDS
T09084
Symbol
GBA2
Name
(RefSeq) non-lysosomal glucosylceramidase
KO
K17108
non-lysosomal glucosylceramidase [EC:
3.2.1.45
]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc00511
Other glycan degradation
emc00600
Sphingolipid metabolism
emc01100
Metabolic pathways
emc04382
Cornified envelope formation
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09100 Metabolism
09103 Lipid metabolism
00600 Sphingolipid metabolism
129334461 (GBA2)
09107 Glycan biosynthesis and metabolism
00511 Other glycan degradation
129334461 (GBA2)
09150 Organismal Systems
09158 Development and regeneration
04382 Cornified envelope formation
129334461 (GBA2)
Enzymes [BR:
emc01000
]
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.45 glucosylceramidase
129334461 (GBA2)
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Paralog
GFIT
Motif
Pfam:
GH116_catalytic
Glyco_hydr_116N
Bac_rhamnosid6H
DUF5127
Glyco_hydro_94
Motif
Other DBs
NCBI-GeneID:
129334461
NCBI-ProteinID:
XP_054842573
UniProt:
A0AA97JQD9
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Position
8:complement(430486..450996)
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AA seq
840 aa
AA seq
DB search
MGRFEGRAGGRGVPRWGWRLCLAHQFSERRKPYQAGDVSPGNALRHLGMALRYCRWWYRT
TRVEKKRPVIDLFNSQPLRQIYGCPLGGFGGGTVTRGWRGDFCRWQLSPGLYHYKAVTAD
QFTVCLRRKGQTVYQQVLSVERPGSLQGWNWGFCGHYAFYHALYPRAWTVYQLPGQDVVL
TCRQVAPIIPHDYQDTSLPVGVFVWEVENNSGEELDVSIMFTFRNGMETKDDRAGGHWNE
PFSLERGGHCVRGVMLHHCLPVNAYTLAISAREKAGTTVTHLTAFNPAGTGQEVWHDLLA
DGKLTSLPGKSKPTEKGEACAAAVCASCTVSANGHGTLELGLAWDMPRIRFGSQEREHHR
RYTRFFGSDGNACPALSHYMLTHYEQWEEKIEAWQRPILENSELPPWYKSALFNELYFLA
DGGTLWLELLPEDAASLGSRPGLSQHLPLLQEYGRFAYLEGQEYLMYNTYDVHFYASFAL
IMLWPKLELSLQYDMAAAVLNEDLRPRLYLMNGQTAQVKLCNVVPHDIGEPGDEPWQRVN
AYLIHDTANWKDLNLKFVLQVYRNYYLVEDSAYLRDMWPICQAVMESELKFDRDGDGLIE
NSGFADQTYDAWVVTGASAYCGGLWLAAVCTMCRMAEILGEDEIQQKYSAILAKGSEAFE
RLLWNGKYYNYDSGRSASSNSIMSDQLAGQWFLRACGLGEGRFEVFPQDHVQTALKTIFE
LNVMGFSEGTMGAVNGMRPSGTPDTSSVQSNEVWVGVVYALAATMIQEGLVEEGFRTAEG
CYRTVWEHLGMAFQTPEAYCQKRVFRSLAYMRPLSIWSMQLAWERRAARVPPAPVNSVGS
NT seq
2523 nt
NT seq
+upstream
nt +downstream
nt
atggggcgcttcgaggggcgcgcgggcgggcggggggtgccgcgctggggctggcggctc
tgcctggcccaccagttctccgagcggcggaagccctaccaggccggcgacgtctccccc
ggcaacgccctgcggcacctgggcatggccctgcggtactgccgctggtggtaccgcacg
acgcgcgtggagaagaagcggccggtcatcgacctcttcaactcgcagccgctgcgccag
atctacggttgcccgctggggggcttcgggggcggcaccgtgacgcgcggctggcggggg
gacttctgccgctggcagctcagcccgggcctctaccactacaaggcggtgacggcggac
cagttcaccgtctgcctgcgccggaagggccagaccgtgtaccaacaggtgctgtcggtg
gagcggccgggcagcctgcagggctggaactggggcttctgcggccactacgccttctac
cacgcgctctacccgcgggcctggaccgtctaccagctccccgggcaggacgtggtgctg
acctgccggcaggtggcccccatcatcccacatgattatcaggataccagcttgcctgtg
ggggtctttgtctgggaggtggagaataacagcggtgaagagctcgatgtctccatcatg
ttcacctttcggaacggcatggagaccaaagacgaccgtgcaggaggtcactggaacgag
cccttcagcctggagagaggcggccactgtgtccggggggtgatgctgcaccactgcctc
cccgtgaatgcctacacgctggcgatctccgcccgggagaaggcaggcaccacagttacc
cacttgacggcgttcaaccctgcgggcaccgggcaagaagtgtggcatgacctcctagct
gatggcaagttgacatccctgccagggaaaagcaagcctacggaaaagggggaggcatgt
gcggcagctgtgtgcgccagctgcacggtgtcggccaacgggcatgggacgctggagctc
ggcctggcctgggatatgcctcggattcgttttggatcccaagagcgggagcatcacagg
cggtacacgcgcttctttggcagcgatgggaatgcgtgccctgccctctcccactacatg
ctcacgcactatgaacaatgggaggagaagatcgaggcctggcagagacccatcttggag
aacagtgagctgcccccttggtacaagtcagccctcttcaacgagctgtacttcctcgcc
gacggagggacgctgtggctggagctgctgccagaggacgcagcctccctgggcagcagg
cctggcctctcccagcaccttccgctcctgcaagagtatggcagatttgcttatttggaa
ggccaggagtacctcatgtacaacacctacgacgtccacttctacgcctccttcgctctg
atcatgctgtggcccaaactagagctcagcctgcagtatgacatggctgctgctgtcctg
aacgaggaccttcggccccggctgtacctgatgaacgggcaaacggcccaggtcaagctc
tgcaatgtggtgccacatgacatcggagagccaggcgatgagccgtggcagcgagtcaat
gcttacctcatccacgatacggcgaactggaaggatttgaacctgaagtttgtgctgcaa
gtctaccgaaactactacctggtggaggactctgcctacctgcgggacatgtggcccatc
tgccaggccgtgatggagtcagaactcaagttcgacagggacggagacggcctgatagag
aactccggctttgctgaccagacgtacgatgcctgggtggtgacgggtgccagtgcctat
tgtggtggcctgtggctagctgccgtctgcacgatgtgccggatggccgagatcttgggc
gaggacgagatccagcagaaatactcggccatcctggccaagggctcggaggcctttgag
aggctgctctggaacggaaaatattacaactatgacagcggccggagtgcttcctccaac
agcatcatgtcggaccagctggcagggcagtggtttctccgggcatgcggcctgggcgag
ggaaggtttgaggttttcccccaggaccacgtgcagactgctttgaagaccatctttgag
ctgaacgtgatgggcttctcagaggggacaatgggggcggtgaatggcatgcggccttct
gggacaccagacacctccagcgtgcagtccaatgaagtgtgggtcggggtggtgtatgca
ctggctgccaccatgatccaggagggcctagtggaggaaggcttccgcaccgcagagggc
tgctaccgcaccgtgtgggagcacctgggcatggccttccagacgcctgaggcctactgc
cagaaaagggtgttccgctcactggcctacatgcgtcccctcagcatctggagcatgcag
ctggcgtgggagcgcagggctgcacgagtgccccctgcccctgtcaactctgttgggtct
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