KEGG   Eublepharis macularius (Leopard gecko): 129335861
Entry
129335861         CDS       T09084                                 
Symbol
MET
Name
(RefSeq) hepatocyte growth factor receptor
  KO
K05099  proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
Organism
emc  Eublepharis macularius (Leopard gecko)
Pathway
emc04010  MAPK signaling pathway
emc04020  Calcium signaling pathway
emc04510  Focal adhesion
emc04520  Adherens junction
emc05100  Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:emc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129335861 (MET)
   04020 Calcium signaling pathway
    129335861 (MET)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    129335861 (MET)
   04520 Adherens junction
    129335861 (MET)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    129335861 (MET)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:emc01001]
    129335861 (MET)
Enzymes [BR:emc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     129335861 (MET)
Protein kinases [BR:emc01001]
 Receptor tyrosine kinases (RTK)
  MET family
   129335861 (MET)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase TIG Sema PSI Kinase-like Pkinase_fungal SHLD1_C
Other DBs
NCBI-GeneID: 129335861
NCBI-ProteinID: XP_054844670
UniProt: A0AA97L6L1
LinkDB
Position
9:77936629..78060229
AA seq 1378 aa
MKPSASGIIVFLLALVPWSDGKCKEAGSRPEMNLNIKYQLPNFTAETPVQNIVLYQHHIY
VGAVNKIYVLNESLHNVFVYKTGPVLENPGCAPCEDCKHKANQSNSTWNDNHNMALLLET
YYEDQLISCGSVAKGTCLRHVIHADNPADIGRDVECMYSNHDESGQCPDCVVSPAGTKVL
VMEKDRFVHFYVGNTVVNLSQPDHLLHSISVRRLKESLDGFKFLTVDSYIDVLPQFRNSY
PIKYIHAFEKDHFVYFLTVQKESLDSQAFHTRIIRFCSFDSELRSYMEMPLECMYTEKRR
KRSTKQSNEVFNILQAAYIGKPGAALAREMGLDMNEDILYGAFAQSKPDSSEPSHKSAVC
LVSIKTINEFFSKIVDRQNMKCLQHLHRKNSKYCLDRSFSRNASYCGAQDDEYLLEVTMA
LPRIDLFAKQFGTVLLTSISVFTKGDLTIANLGTSAGRFMQIVISRSAHTTPYVNFQLDF
HPVSPEVIIENSPGDNGYILAVTGNRITKIPLNGPGCSHFNTCSQCLLSPAFMKCGWCGD
RCTRSGECNVGEWTQETCLPRLNEILPRNVPFDGATRLTLCGWDFGFSKTNKFSLQTMSV
LIGGQRCILDVKASDKNKLECTVGAVRNPSFNVSSTVSNGHANISFNTFSYVNPIIRSIS
PSYGPRFGGTLLTLTGEYLSSGNSQEVFVGEKQCNLTRVSDTTIECYTPKQGDQSECLVR
MKIDAVFRFAGQFIYRENPAVYKIYPAKSFLSGGSTITAQGINLNSAFSPKMVVTVPKLH
RNFTVACSHRSNYEIICCTTPSLKPYKLTLPFVTKVFFVFDGINSSHFNFDYVNDPSFTF
SEKPVVISQGNQNIVIKGNNIDSEAVKGEVLKVGNKSCENITLKFQSVSCTVPTELLKSN
SQLNIEWKKEVSSVLIGKVMVLPDENFNGLIAGAVSVSVFLLLVFSGLFLWRKKRKQIKD
LGREIVRYDGRVHTPHLDRLVSARSVSPTTEMVSSESVDYRSTFLEDQFPALSQNGSCRP
AQYPHSDLSPILSTGDSDLASPLLQTHVHIDIGALNPDLVKEVEHVVIGADSLIVHFSEV
IGRGHFGCVYHGTLLDTDDKKIHCAVKSLNRITDLDEVAQFLKEGIIMKDFTHPNVLSLL
GICLPNEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHR
DLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTK
SDVWSFGVLLWELMTRGAPPYPDVNSFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPK
PELRPAFSELVSDISTIFTTFVGEHYVHVNATYVNVKCVAPYPSLLSSQDNIDRDSDT
NT seq 4137 nt   +upstreamnt  +downstreamnt
atgaagccttccgcctctgggattattgtatttctgttggccttggtaccatggagtgat
gggaaatgtaaagaagcaggttcaaggccagagatgaatctgaacatcaaatatcagctt
cccaacttcactgcagaaactccagtgcaaaatatagttctgtaccagcaccatatctac
gttggagcagtcaacaaaatctacgtcttaaacgaaagccttcacaatgtctttgtgtac
aagactggacctgtgctggagaatcctggctgtgccccttgtgaagattgtaaacataaa
gcaaaccaatccaatagcacttggaacgataaccacaacatggcactacttttagaaaca
tactatgaagatcagctcattagctgcggtagtgttgcaaaaggaacttgcctgcgccat
gtcattcatgctgataaccctgctgacattggcagggatgtggagtgtatgtactcaaac
catgatgagtcaggccagtgtccggattgtgttgtaagccctgcagggactaaagtccta
gtcatggaaaaggacaggtttgtgcatttctatgttggaaacacagtagtgaatttatcc
cagccagaccatttactgcattcaatatcagttcgaagattaaaagaaagcctagatgga
tttaagtttctcaccgttgactcgtatattgatgtccttccacaattcaggaattcctac
cccattaagtatattcatgcctttgaaaaggaccacttcgtatactttctcactgtccag
aaagaatctcttgattcccaggcttttcacacaaggatcatacggttctgctcttttgat
tctgagttgcgttcatatatggaaatgccgcttgagtgcatgtacactgaaaaacgtagg
aagaggtcaaccaagcagtccaatgaggtctttaatattttgcaggctgcatatattggt
aagccaggagcagccttagcccgggaaatgggccttgatatgaacgaggatattttatat
ggtgcctttgcccaaagtaaaccagactcttcagaaccgtctcataaatctgctgtctgc
ttagtctctattaaaaccatcaatgaattcttcagcaagattgtagacagacaaaacatg
aaatgtcttcagcatctccataggaagaacagcaaatactgcttggacaggtctttttca
agaaatgcgtcttactgcggagcgcaagatgacgagtatctactggaggttacaatggct
ttgccacggattgacttatttgcaaagcagttcggcactgtcctcttaacgtccatatct
gtcttcactaaaggggatcttaccatagcgaatcttgggacatctgcaggccgtttcatg
cagatagtgatttctcgttcagcacacacaacaccatatgtgaatttccagctagatttt
catcctgtttctccagaagttataattgaaaattcgcccggcgataatggatatatcttg
gcagtcactgggaataggataacaaagattcccctaaacggaccaggttgttctcatttc
aatacctgcagtcagtgtcttttgtcacctgccttcatgaagtgtggttggtgtggtgat
cgatgtacgcgatctggggagtgcaatgttggagagtggacacaagagacatgtctaccc
agactcaatgagattcttccaagaaatgtaccttttgacggtgcaactcgactgacatta
tgtgggtgggacttcggattcagcaaaactaacaaattcagtttacaaaccatgtcggtt
cttatcggtggacaacgatgcattctggatgtcaaagcaagtgacaaaaacaaactggaa
tgtactgttggtgctgtcaggaatccaagctttaacgtttcaagcactgtttcaaatgga
catgctaatatttccttcaatacgttctcttatgtgaatccgataataagaagtatctca
cccagctatggcccaagatttggtgggacattgctgacattaaccggggaatacctcagc
agtgggaattctcaagaggtttttgttggtgaaaagcagtgcaatttaacaagagtgtct
gacaccaccatagagtgttacacccctaaacaaggagaccagtcagagtgtcttgtgaga
atgaaaattgatgcagtctttcgttttgcgggtcaatttatatacagagaaaaccctgct
gtttataaaatttatccagccaaatcctttctgagtggtggaagcacaattacagcccag
ggaatcaacctgaattcagcattctccccaaagatggttgtaacagtccctaaactgcac
aggaactttactgtggcctgtagccatcgctccaattatgagataatttgctgtacaact
ccttcgctaaaaccctataaactgacattgccttttgtgacaaaagtgtttttcgttttt
gatggtatcaactcatcacattttaattttgattatgtgaatgaccccagctttacattt
tctgaaaaaccagtggtgatttctcaaggaaaccaaaatatagtcattaagggaaataat
atcgactcagaagctgttaaaggtgaagtgctaaaggttggaaacaagagctgtgaaaac
atcaccttgaagtttcaatctgtttcttgtactgttcccacagaactgctgaaatccaat
agtcaactgaatatagagtggaaaaaggaagtttcttcagtacttattgggaaagtaatg
gttctgccagatgagaatttcaatgggctcattgcaggagctgtgtcagtatctgttttt
ctattgttggtgttttcggggcttttcctctggagaaaaaagagaaagcaaatcaaagac
ttaggcagagagattgttcgctacgatggaagagtgcacactcctcacctggacaggctt
gtaagcgcaagaagtgtgagtcccacaacggaaatggtgtcgagtgaatctgttgattac
agatccacttttctagaagatcagtttccagctttgtctcagaatggatcgtgcaggcca
gctcagtatcctcactcagatttatctcccattttgtctactggagactctgatttagcc
agcccattgttgcagacgcacgtccacattgacattggtgccttaaatccggatttggtc
aaagaagttgagcacgtggttattggcgccgatagcctgatagtgcattttagtgaagta
ataggaaggggtcactttgggtgtgtctatcatgggactttgctggatactgacgacaag
aaaatccattgtgctgtgaagtccttgaataggattacagacttggatgaagtagctcag
tttctgaaagaggggatcataatgaaagatttcactcatcccaatgtcctgtctctgctt
ggaatttgcttgcccaatgaggggtctcccttggtggtgcttccatacatgaaacatgga
gatcttcggaacttcattaggaacgagactcacaatccgacggtaaaagatttgattggt
tttggcctgcaagtagcaaaggggatgaagtaccttgcaagcaagaagtttgtccataga
gacttagcagcaagaaattgtatgctggatgaaaaattcactgttaaggttgctgatttt
ggccttgctcgagatgtctacgataaggagtactacagtgtacacaataaaacaggagcc
aaactgccagtaaaatggatggctttagaaagtttgcaaactcagaagttcactacaaag
tcagatgtgtggtcctttggagtgttactttgggagctgatgacgagaggagcaccacct
tatccagacgtaaactcttttgatatcactgtttacttactgcaaggaagaaggctcttg
cagcctgagtattgcccagacccactatatgaagtcatgcttaaatgttggcatcccaaa
cctgaactacggccagcattctctgagctagtttcagatatatcaaccatcttcaccact
ttcgttggggaacattatgttcacgtgaacgcaacctatgtcaatgtgaaatgtgtggca
ccttatccatctcttctgtcgtcccaagacaacatagatagggattcagatacatga

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